المؤلفون: Roy M. Pemberton, Timothy Cox, Rachel Tuffin, Guido A. Drago, John Griffiths, Robin Pittson, Graham Johnson, Jinsheng Xu, Ian C. Sage, Rhodri Davies, Simon K. Jackson, Gerry Kenna, Richard Luxton, John P. Hart

المصدر: Sensors, Vol 14, Iss 11, Pp 20519-20532 (2014)

مصطلحات موضوعية: microbiosensor, screen-printing, MEMS, 96-well plate, metabolism, amperometry, cell monitoring, toxicity testing, Chemical technology, TP1-1185

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1424-8220/14/11/20519; https://doaj.org/toc/1424-8220

URL الوصول: https://doaj.org/article/a4da000d433b417fae95ff935ed1e5aa

المؤلفون: Nicola Melillo, Daniel Scotcher, J. Gerry Kenna, Claudia Green, Catherine D. G. Hines, Iina Laitinen, Paul D. Hockings, Kayode Ogungbenro, Ebony R. Gunwhy, Steven Sourbron, John C. Waterton, Gunnar Schuetz, Aleksandra Galetin

المصدر: Pharmaceutics, Vol 15, Iss 3, p 896 (2023)

مصطلحات موضوعية: gadoxetate, pharmacokinetics, hepatic transporters, modelling and simulation, DCE-MRI, OATP1B, Pharmacy and materia medica, RS1-441

Relation: https://www.mdpi.com/1999-4923/15/3/896; https://doaj.org/toc/1999-4923; https://doaj.org/article/ad3d7aef2cea4895a8dd3d1fd0b8d311

الاتاحة: https://doi.org/10.3390/pharmaceutics15030896
https://doaj.org/article/ad3d7aef2cea4895a8dd3d1fd0b8d311

المؤلفون: Andresa Heemann Betti, John Gerry Kenna, Terry R. Van Vleet, Palanisamy Aruselvan, Liz Girardi Müller

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: preclinical assays, drug discovery, toxicity, in vitro, in vivo, Therapeutics. Pharmacology, RM1-950

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1225806/full; https://doaj.org/toc/1663-9812; https://doaj.org/article/3552e2ba5aa84c33985431f55c5232f7

الاتاحة: https://doi.org/10.3389/fphar.2023.1225806
https://doaj.org/article/3552e2ba5aa84c33985431f55c5232f7

المؤلفون: Chihae Yang, James F Rathman, Bruno Bienfait, Matthew Burbank, Ann Detroyer, Steven J. Enoch, James W. Firman, Steve Gutsell, Nicola J. Hewitt, Bryan Hobocienski, Gerry Kenna, Judith C. Madden, Tomasz Magdziarz, Jörg Marusczyk, Aleksandra Mostrag-Szlichtyng, Christopher-Tilman Krueger, Cathy Lester, Catherine Mahoney, Abdulkarim Najjar, Gladys Ouedraogo, Katarzyna R. Przybylak, J. Vinicius Ribeiro, Mark T.D. Cronin

المصدر: Computational Toxicology. 26:100272

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Toxicology, Computer Science Applications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5741cc1baeed6bd50fa239de98753095
https://doi.org/10.1016/j.comtox.2023.100272

المؤلفون: Franck A. Atienzar, Eric A. Blomme, Minjun Chen, Philip Hewitt, J. Gerry Kenna, Gilles Labbe, Frederic Moulin, Francois Pognan, Adrian B. Roth, Laura Suter-Dick, Okechukwu Ukairo, Richard J. Weaver, Yvonne Will, Donna M. Dambach

المصدر: BioMed Research International, Vol 2016 (2016)

مصطلحات موضوعية: Medicine

Relation: http://dx.doi.org/10.1155/2016/9737920; https://doaj.org/toc/2314-6133; https://doaj.org/toc/2314-6141; https://doaj.org/article/50f0abf09f6a42c4bc87218dda0b0e1a

الاتاحة: https://doi.org/10.1155/2016/9737920
https://doaj.org/article/50f0abf09f6a42c4bc87218dda0b0e1a

المؤلفون: Nicola J. Hewitt, John Troutman, Julia Przibilla, Andreas Schepky, Gladys Ouédraogo, Catherine Mahony, Gerry Kenna, Mustafa Varçin, Mathew P. Dent

المصدر: Regulatory Toxicology and Pharmacology. 131:105132

مصطلحات موضوعية: Humans, Ethylene Glycols, Cosmetics, General Medicine, Toxicology, Risk Assessment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d44e5cbbed969e3412b051dc7b37a3
https://doi.org/10.1016/j.yrtph.2022.105132

المؤلفون: Cell Biomarkers, Roy M. Pemberton, Timothy Cox, Rachel Tuffin, Guido A. Drago, John Griffiths, Robin Pittson, Graham Johnson, Jinsheng Xu, Ian C. Sage, Rhodri Davies, Simon K. Jackson, Gerry Kenna, Richard Luxton, John P. Hart

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1424-8220/14/11/20519/pdf/.

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.660.9142; http://www.mdpi.com/1424-8220/14/11/20519/pdf/

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.660.9142
http://www.mdpi.com/1424-8220/14/11/20519/pdf/

المؤلفون: Garside, Helen, Marcoe, Karen F., Chesnut-Speelman, Jessica, Foster, Alison J., Muthas, Daniel, Gerry Kenna, J., Warrior, Usha, Bowes, Joanne, Baumgartner, James

المصدر: Toxicology in Vitro ; volume 28, issue 2, page 171-181 ; ISSN 0887-2333

الاتاحة: http://dx.doi.org/10.1016/j.tiv.2013.10.015
https://api.elsevier.com/content/article/PII:S0887233313002701?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0887233313002701?httpAccept=text/plain

المؤلفون: Gladys Ouedraogo, Camilla Alexander-White, Dagmar Bury, Harvey J. Clewell, Mark Cronin, Tom Cull, Matthew Dent, Bertrand Desprez, Ann Detroyer, Corie Ellison, Stefania Giammanco, Eric Hack, Nicola J. Hewitt, Gerry Kenna, Martina Klaric, Reinhard Kreiling, Cathy Lester, Catherine Mahony, Enrico Mombelli, Jorge Naciff, John O'Brien, Andreas Schepky, Sarah Tozer, Bart van der Burg, Barbara van Vugt-Lussenburg, Sharon Stuard, null Cosmetics Europe

المصدر: Regulatory toxicology and pharmacology : RTP. 132

مصطلحات موضوعية: Reproduction, Preservatives, Pharmaceutical, Parabens, General Medicine, Cosmetics, Toxicology, Risk Assessment, RS

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4309dbeaf4d25867d81982bd4812f818
https://pubmed.ncbi.nlm.nih.gov/35508214

المؤلفون: Bertrand Desprez, Alicia Paini, Nicola J. Hewitt, Catherine Mahony, Mark T. D. Cronin, Cathy Lester, Eric Hack, Gerry Kenna, Andreas Schepky, James W. Firman, Alina Efremenko, Harvey J. Clewell, Martina Klaric, Camilla Alexander-White, Cosmetics Europe, Dagmar Bury, Ann Detroyer, Gladys Ouedraogo

المصدر: Regulatory toxicology and pharmacology : RTP. 123

مصطلحات موضوعية: RM, media_common.quotation_subject, Cosmetics, Pharmacology, Toxicology, Risk Assessment, RS, chemistry.chemical_compound, Animal data, Eating, Theophylline, Caffeine, Toxicity Tests, Medicine, Animals, Humans, Mode of action, Theobromine, Paraxanthine, Exposure assessment, media_common, business.industry, General Medicine, chemistry, Xanthines, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563d92294b6d51bc097fb99bbbd42ff6
https://pubmed.ncbi.nlm.nih.gov/33905778

المؤلفون: J. Gerry Kenna, Jack Uetrecht

المصدر: Drug Metabolism and Disposition. 46:1658-1669

مصطلحات موضوعية: Risk, 0301 basic medicine, Drug, Idiosyncratic drug reaction, media_common.quotation_subject, Pharmaceutical Science, Pharmacology, Immune tolerance, 03 medical and health sciences, Immune system, Drug Discovery, medicine, Animals, Humans, Cytotoxicity, media_common, Liver injury, Drug discovery, Chemistry, In vitro toxicology, medicine.disease, 030104 developmental biology, Liver, Hepatocytes, Biological Assay, Chemical and Drug Induced Liver Injury

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3142799f848ce710abc09598107c48
https://doi.org/10.1124/dmd.118.082719

المؤلفون: J Gerry Kenna

المصدر: Expert Opinion on Drug Metabolism & Toxicology. 13:567-574

مصطلحات موضوعية: 0301 basic medicine, Drug, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Endpoint Determination, media_common.quotation_subject, Pharmacology, Toxicology, 03 medical and health sciences, Species Specificity, In vivo, Human biology, Toxicity Tests, medicine, Animals, Humans, Intensive care medicine, media_common, Cardiotoxicity, Toxicity data, business.industry, In vitro toxicology, General Medicine, Clinical trial, 030104 developmental biology, Drug Design, Toxicity, Chemical and Drug Induced Liver Injury, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ba9fe2f249db825bbb1f51bf0ad86a
https://doi.org/10.1080/17425255.2017.1290082

المؤلفون: J Gerry Kenna, Rebecca Ram

مصطلحات موضوعية: Cardiotoxicity, business.industry, Drug discovery, Toxicity, Medicine, Drug reaction, business, Bioinformatics, medicine.disease_cause, Genotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fc08e453e5d790290f4386a4a2d3305e
https://doi.org/10.1016/b978-0-12-813697-3.00020-2

المؤلفون: Gerry Kenna

المصدر: Drug Metabolism and Pharmacokinetics. 35:S1-S2

مصطلحات موضوعية: Pharmacology, Liver injury, Drug discovery, business.industry, Perspective (graphical), medicine, Pharmaceutical Science, Pharmacology (medical), Transporter, Bioinformatics, medicine.disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::263d92056bb6d0e7db9063da268e09e7
https://doi.org/10.1016/j.dmpk.2020.04.271

المؤلفون: Katya Tsaioun, J. Gerry Kenna, Kathy Archibald, Pandora Pound

المصدر: J R Soc Med

مصطلحات موضوعية: 0301 basic medicine, Organizational innovation, Knowledge management, Letter, Drug Industry, business.industry, MEDLINE, General Medicine, Organizational Innovation, United Kingdom, United States, Interviews as Topic, 03 medical and health sciences, 030104 developmental biology, SAFER, Drug Discovery, Microchip Analytical Procedures, Medicine, Humans, Safety, business, Drug industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d13e8b9c33f46c29465fbf89267d0f
https://pubmed.ncbi.nlm.nih.gov/31074338

المؤلفون: J. Gerry Kenna, Elizabeth Baker, Lorna Ewart, J. Lowry Curley, Jane M. Gunther, Bruce A. Donzanti, Helene D. Clayton-Jeter, Michael N. Liebman, Catherine L. Pugh, Paul B. Watkins, Kristie Sullivan, Nancy Beck, Edward L. LeCluyse, Ellen L. Berg, P. Charukeshi Chandrasekera

المصدر: Drug discovery today. 24(2)

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Knowledge management, business.industry, In silico, MEDLINE, Drug Evaluation, Preclinical, Animal Testing Alternatives, 03 medical and health sciences, Patient safety, 030104 developmental biology, 0302 clinical medicine, Drug development, Inventions, 030220 oncology & carcinogenesis, Animal Testing Alternative, Drug Discovery, Medicine, Humans, Patient Safety, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2f74ee070428cbc34f62177a9ee7ff
https://pubmed.ncbi.nlm.nih.gov/30468877

المؤلفون: Joseph W. Polli, Jonathan Maher, Kunal S Taskar, A. David Rodrigues, Christoph Funk, Michael J. Hafey, Robert W. Yucha, Kim L. R. Brouwer, Y. Anne Pak, Paul B. Watkins, David Dai, Jenny M. Pedersen, David L. Bourdet, Kyunghee Yang, Christina Battista, J. Gerry Kenna, Yurong Lai, Kenneth R. Brouwer

المصدر: Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: 0301 basic medicine, Drug, Protein Conformation, media_common.quotation_subject, Reviews, Pharmacology, In Vitro Techniques, Models, Biological, Risk Assessment, 03 medical and health sciences, Structure-Activity Relationship, Drug Development, In vivo, Risk Factors, Membrane Transport Modulators, Drug Discovery, medicine, Animals, Bile, Humans, Pharmacology (medical), Computer Simulation, ATP Binding Cassette Transporter, Subfamily B, Member 11, Cells, Cultured, media_common, Liver injury, Mechanism (biology), Drug discovery, business.industry, In vitro toxicology, medicine.disease, Bile Salt Export Pump, 3. Good health, 030104 developmental biology, Liver, Drug Design, Computer-Aided Design, Chemical and Drug Induced Liver Injury, Risk assessment, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd2fea4f00c01969bbedd865b180a28
https://pubmed.ncbi.nlm.nih.gov/30137645

المؤلفون: Michael D. Aleo, Deborah S. Light, J. Gerry Kenna

المصدر: Methods in Pharmacology and Toxicology ISBN: 9781493976768

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Toxicity, Medicine, Computational biology, business, Interpretation (model theory)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e53444d49968ffdd18e7146aa0ce0d44
https://doi.org/10.1007/978-1-4939-7677-5_17

المؤلفون: Andreas Baudy, Manishkumar Patel, Paul D. Hockings, Daniel Scotcher, John C. Waterton, Aleksandra Galetin, J. Gerry Kenna, Gunnar Schuetz, Steven Sourbron, Catherine D. G. Hines, Sabina Ziemian

المصدر: Drug-Induced Liver Toxicity
Methods in Pharmacology and Toxicology ISBN: 9781493976768
Kenna, J G, Waterton, J C, Baudy, A, Galetin, A, Hines, C D G, Hockings, P, Patel, M, Scotcher, D, Sourbron, S, Ziemian, S & Schuetz, G 2018, Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury . in Drug-Induced Liver Toxicity . Methods in Pharmacology and Toxicology, no. 9781493976768, Humana Press, Inc, New York, NY, pp. 627-651 . https://doi.org/10.1007/978-1-4939-7677-5_30
Methods in Pharmacology and Toxicology
Methods in Pharmacology and Toxicology-Drug-Induced Liver Toxicity

مصطلحات موضوعية: Drug, Drug-induced liver injury, Gadoxetate, media_common.quotation_subject, Hepatobiliary transporters, Causality assessment, Pharmacology, 030226 pharmacology & pharmacy, 030218 nuclear medicine & medical imaging, Drug labelling, Pharmacology, Toxicology and Pharmaceutics(all), 03 medical and health sciences, 0302 clinical medicine, Medicine, Drug-drug interactions, Pharmacology (medical), Clinical imaging, media_common, Liver injury, business.industry, Hepatotoxicity, Transporter, medicine.disease, Bile Salt Export Pump, 3. Good health, Molecular Medicine, Bile salt export pump, business, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9d95eadbc9aaa8385974439dd215e6

المؤلفون: Lee Faulkner, Gerry Kenna, Anja Kipar, Dean J. Naisbitt, Ryan Nattrass, Jean-François Nicolas, B. Kevin Park, Daniel J. Antoine, Marc Vocanson

المساهمون: MRC Centre for Drug Safety Science, Department of Pharmacology & Therapeutics, University of Liverpool, Immunologie de l'allergie cutanée et vaccination – Immunology of skin allergy and vaccination, Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), AstraZeneca, Vetsuisse Faculty, Vetsuisse Faculty University Zürich, Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Zurich, Naisbitt, Dean J

المصدر: Toxicological Sciences
Toxicological Sciences, Oxford University Press (OUP), 2015, 146 (1), pp.146-156. ⟨10.1093/toxsci/kfv077⟩
Toxicological Sciences, 2015, 146 (1), pp.146-156. ⟨10.1093/toxsci/kfv077⟩

مصطلحات موضوعية: 10184 Institute of Veterinary Pathology, 610 Medicine & health, Biology, immunogenicity, CD8-Positive T-Lymphocytes, Toxicology, 142-005 142-005, Floxacillin, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, polycyclic compounds, Mesenteric lymph nodes, Cytotoxic T cell, Animals, Antigen-presenting cell, 030304 developmental biology, Liver injury, flucloxacillin, 0303 health sciences, 3005 Toxicology, medicine.disease, Acquired immune system, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, 3. Good health, Anti-Bacterial Agents, Granzyme B, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Hepatocyte, Immunology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Cancer research, Hepatocytes, 570 Life sciences, biology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Flucloxacillin, medicine.drug, liver injury

وصف الملف: ZORA_NL_154487.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94ce203f16d582a964f9dcb4d6a328b
http://doc.rero.ch/record/290619/files/kfv077.pdf