يعرض 1 - 20 نتائج من 51 نتيجة بحث عن '"German Shipulin"', وقت الاستعلام: 0.56s تنقيح النتائج
  1. 1
    Academic Journal
  2. 2
    Academic Journal
  3. 3
    Academic Journal
  4. 4
    Academic Journal
  5. 5
    Academic Journal
  6. 6
    Academic Journal

    المؤلفون: Jun Bao, Yi-Hui Wang, Quan-Hua Liu, Yi-Xiao Bao, Nurit Azouz, Julie Caldwell, Leanne Ray, Mark Rochman, Melissa Mingler, Matthew Eilerman, Ting Wen, Jocelyn Biagini Myers, Gurjit Khurana Hershey, Leah Kottyan, Lisa Martin, Rothenberg Marc, Victor Gonzalez-Uribe, Jaime Del Rio-Chivardi, Blanca Del Rio-Navarro, Hongfei Lou, Siyuan Ma, Yan Zhao, Feifei Cao, Fei He, Zhongyan Liu, Chengshuo Wang, Claus Bachert, Luo Zhang, Elissa Abrams, Allan Becker, Amit Kandhare, Subhash Bodhankar, Nicole Grossman, Gheorghe Doros, Francine Laden, Anne Fuhlbrigge, Michael Wechsler, Wilson Pace, Barbara Yawn, Elliot Israel, Junehyuk Lee, Frederick Adler, Peter Kim, Yung Feng Huang, Ying Yao Chen, Chiun Yen Pan, Herng Sheng Lee, Michael Khalemsky, David G. Schwartz, Pavel Kolkhir, Dmitry Pogorelov, Nikolay Kochergin, Hirsh Komarow, Michael Young, Robin Eisch, Linda Scott, Dean Metcalfe, Alexander Singer, Andrew Wakeman, Thomas Gerstner, Woo-Jung Song, Ji-Su Shim, Ha-Kyeong Won, Sung-Yoon Kang, Kyoung-Hee Sohn, Byung-Keun Kim, Eun-Jung Jo, Min-Hye Kim, Sang-Heon Kim, Heung-Woo Park, Sun-Sin Kim, Yoon-Seok Chang, Alyn H. Morice, Byung-Jae Lee, Sang-Heon Cho, Kyung-Up Min, Maria Assunta Boscolo, Giulio Brivio, Sergio Bosisio, Nicoletta Manzocchi, Edoardo Pulixi, Giulia Grignani, Eloisia D’Andrea, Massimo Ricci, Elena Passini, Maurizio Italia, Marilyn Urrutia-Pereira, Stefani Fagundes, Vinicius Jardim Oliano, Dirceu Solé, Sadia Benzaquen, Alejandro Aragaki, Ricardo Balestra, Dawn Harden, Danielle Caudell-Stamper, Gilbert Glady, Mark Holbreich, Nataliya Lyakhovska, Igor Kaidashev, Jaromir Bystron, Beata Hutyrova, Galina Balakirski, Luk Vanstreels, Gerda Wurpts, Hans F. Merk, Jens Malte Baron, Johanna Plange, Hans-Peter Rihs, Monika Raulf, Stefani Roeseler, Alberto Tolcachier, Armando Chamorro, Ruth Otero, Joel Brooks, Michael Hess, Jared Benz, Joseph MacDonald, Usma Chatha, Dale Lent, Şükran Köse, Bengü Gireniz Tatar, Gülgün Akkoçlu, İbrahim Çukurova, İlker Ödemiş, Ayşin Kılınç Toker, Abdullahi Hasssan, Abdulrazaq Abdullahi Gobir, Cheol-Woo Kim, Young Hwa Choi, Jeong Hye Lee, Rae Jeong Cho, Yu Ran Nam, Joo Hyun Nam, Woo Kyung Kim, Ivana Filipovic, Zorica Zivkovic, Djordje Filipovic, Dana Shik, Andrew Smith, Wang Yui Hsi, Stuart Friedman, Yonatan Gizaw, Rima Bakhda, Kumail Mohammed, Richard Wasserman, Angela Hague, Deanna Pence, Joanna Rolen, Robert Sugerman, Stacy Silvers, Qurat Kamili, Nadezhda Knauer, Alexandr Zazernyi, Elena Blinova, Daria Demina, Vladimir Kozlov, Komal Agrawal, Sagar Kale, Naveen Arora, Volha Vasilkova, Tatiana Mokhort, William Silvers, Rachel Eisenberg, Rushita Mehta, Arye Rubinstein, Antony Aston, Paul Turner, Monica Ruiz-Garcia, Robert Boyle, Simon Brown, Yael Dinur Schejter, Adi Ovadia, Vy Kim, Brenda Reid, Chaim Roifman, Lana Rosenfield, Ernie Avilla, Laurie Harada, Marilyn Allen, Susan Waserman, Ho Joo Yoon, Gun Woo Koo, Suk-Il Chang, Hye-Ran Yoon, Dong Won Park, Tai Sun Park, Ji-Yong Moon, Tae Hyung Kim, Jang Won Sohn, Dong Ho Shin, Tsici Jorjoliani, Lia Jorjoliani, Nino Adamia, Nona katamadze, Deepika Ramachandra, Liana Jorjoliani, Rusudan Karseladze, Lali Saginadze, Natalia Chkuaseli, Anna Dolgova, Olga Stukolova, Anna Sudina, Anna Cherkashina, German Shipulin, Richard Rosenthal, Harvey Howe, Paul Knause, Rony Greemberg, Jean Jacques De Bruycker, Isabel Fernandez, Françoise Le Deist, Elie Haddad, Yeong Ho Rha, Kyung Suk Lee, Sun Hee Choi, Herman Tam, Estelle Simons, Elinor Simons, Maria Golebiowska-Wawrzyniak, Katarzyna Markiewicz, Yoram Faitelson, Miguel Stein, Avigdor Mandelberg, Ilan Dalal, Michael Levin, Lelani Hobane, Wisdom Basera, Maresa Botha, Claudia Gray, Heather Zar, Biserka Jovkovska Kjaeva, Zoran Arsovski, Vesna Grivcheva-Panovska, Adeyinka Odebode, Adedotun Adekunle, Peter Adeonipekun, Ebenezer Farombi, Nadezhda Camacho-Ordoñez, Alejandrina Josefina Martinez-Vázquez, María de la Luz H. García-Cruz, Qi Tan, Rui Min, Guan-qun Dai, Wei-Ping Xie, Huang Mao, Hong Wang, Rakesh Yadav, Sneha Singh, Divya Yadav, Ekaterina Khaleva, Henry T. Bahnson, Amber Franz, Lene Heise Garvey, Nicola Jay, Rubaiyat Haque, Adam Fox, Gideon Lack, George du Toit, Snezana Radic, Branislava Milenkovic, Ana Neskovic, Ljiljana Danojevic, Liat Nachshon, Michael Goldberg, Michael Levy, Yitzhak Katz, Arnon Elizur, Cristine Rosario, Juliana Kasper, Herbeto Chong-Neto, Carlos Riedi, Nelson Rosario, Michael B. Levy, Ronly Har-Even, Mor Carmel, Michael R. Goldberg, Maia Kherkheulidze, Nani Kavlashvili, Eka Kandelaki, Nino Adamai, Irma Ubiria, Andrea Burke, Monika Kastner, Denica Zheleva, Razvigor Darlenski, Konstantinos Bozinakis, Anastasios Kriebardis, Sofia Styliara, Aikaterini Karastathi, Nikolaos Farmakas, Maria Luiza Kraft Kohler Ribeiro, Ana Carolina Barcellos, Hannah Gabriele Ferreira Silva, Luís Henrique Mattei Carletto, Marcela Carolina Bet, Nathalia Zorze Rossetto, Nelson Augusto Rosario, Herberto Jose Chong-Neto, Fernanda Valença, Marina Novaes, Mariana Gomes, Carla Seifert, Alfredo Neto, Flavia Loyola, José Rios, Tatiana Silva, Aline Neves, Oznur Abadoglu, Bilun Gemicioglu, Hasan Bayram, Arif Cimrin, Levent Akyildiz, Aykut Cilli, Hakan Gunen, Tevfik Ozlu, Mecit Suerdem, Esra Uzaslan, Zeynep Misirligil, Snezana Ristic-Stojanovic, A. Milicevic, A. Milenkovic, Jelena Cvejic, Jelena Jankovic, Sanja Dimic-Janjic, Natasa Djurdjevic, Vladyslava Barzylovych, Tetiana Umanets, Anastasia Barzylovych, Karyn Winkler, Jessica Margarinos, Dylan Martin, Maja Nowakowski, Rauno Joks, Tsili Zangen, Olga Bernadsky, Mona Boaz, Gratiana Hermann, Rachel Aviv, Olga Kuperboim, Larisa Ramichanov, Efrat Broide, Raanan Shamir, Noam Zevit, Ron Shaoul, Alex Fich, Arie Levine, Isaac Melamed, Roopesh Singh Gangwar, Yael Minai-Fleminger, Mansour Seaf, Amichai Gutgold, Aarti Shikotra, Anoop Chauhan, Stephen Holgate, Peter Bradding, Peter Howarth, Ron Eliashar, Neville Berkman, Francesca Levi-Schaffer, Sung-il Woo, Betul Celik, Tangul Bulut, Arzu Didem Yalcin, Luiz Querino Caldas, Ronit Confino-Cohen, Yossi Rosman, Arnon Goldberg, Oded Breuer, Roopesh Singh, Ahlam Barhoum, Eitan Kerem, Tatiana Slavyanskaya, Revaz Sepiashvili, Elena A. Blinova, Ekaterina A. Pashkina, Marina I. Leonova, Vera M. Nepomnyaschikh, Darya V. Demina, Vladimir A. Kozlov, Revital Shamri, Kristen M. Young, Peter F. Weller, Rodolfo de Paula Vieira, Manoel Carneiro Oliveira-Junior, Nilsa Regina Damasceno-Rodrigues, Fernanda Magalhães Arantes-Costa, Milton Arruda Martins, Ana Paula Ligeiro Oliveira, Alfred Bernard, Antonia Sardella, Catherine Voisin, Simon Royce, Hamish Philpott, Sanjay Nandurkar, Francis Thien, Peter Gibson, Rodolfo Bianchini, Franziska Roth-Walter, Anna Ohradanova-Repic, Gerlinde Hofstetter, Ina Herrmann, Maria Isabel Carvalho, Karin Hufnagl, Erika Bajna, Georg Roth, Hannes Stockinger, Erika Jensen-Jarolim, Meital Almog, Aharon Kessel, Larisa Apov, Carlos Sanchez Salguero, Alvaro Sanchez Chacon, Abbos Nazarov, Shaxbos Ergashev, Irina Nesterova, Svetlana Kovaleva, Galina Chudilova, Ludmila Lomtatidze, Sarah De Schryver, Alizee Dery, Ann Clarke, Kari Nadeau, Kimberly Weatherall, Celia Greenwood, Denise Daley, Yuka Asai, Moshe Ben-Shoshan, Irina Balmasova, Elena Malova, Stefanie Wagner, Luis F. Pacios, Michael Wallner, Markus Wiederstein, Anna E. Tevs, Nataly Tataurshchikova, Baigalmaa Sangidorj, Anna Ronzhina, Manana Chikhladze, Oliver F. Wirz, Willem van de Veen, David Mirer, Hideaki Morita, Can Altunbulakli, Sebastian L. Johnston, Nicholas Glanville, Nikolaos G. Papadopoulos, Cezmi A. Akdis, Mübeccel Akdis, Avner Reshef, Marc Riedl, Vesna Grivcheva Panovska, Dumitru Moldovan, James Baker, William H. Yang, Sladjana Andrejevic, Richard F. Lockey, Roman Hakl, Shmuel Kivity, Luca Bellizzi, Joseph R. Harper, Anurag Relan, Marco Cicardi

    المصدر: World Allergy Organization Journal, Vol 10, Iss S1, Pp 1-39 (2017)

    مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607

    وصف الملف: electronic resource

  7. 7
    Academic Journal
  8. 8
    Academic Journal
  9. 9
    Academic Journal
  10. 10
  11. 11
    Academic Journal
  12. 12
  13. 13
    Academic Journal

    المصدر: HIV Infection and Immunosuppressive Disorders; Том 13, № 3 (2021) ; ВИЧ-инфекция и иммуносупрессии; Том 13, № 3 (2021) ; 2077-9828 ; 10.22328/2077-9828-2021-13-3

    Relation: https://hiv.bmoc-spb.ru/jour/article/downloadSuppFile/593/405; https://hiv.bmoc-spb.ru/jour/article/downloadSuppFile/593/406; Wang Q. and Zhang L. Broadly neutralizing antibodies and vaccine design against HIV-1 infection. // Front Med. 2020 Feb;14(1):30-42. doi:10.1007/s11684-019-0721-9.; Zhu P., Liu J., Bess J., Chertova E., Lifson J.D. et al. Distribution and three-dimensional structure of AIDS virus envelope spikes. // Nature. 2006 Jun 15;441(7095):847-52. doi:10.1038/nature04817.; Wyatt R. and Sodroski J. The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens. // Science. 1998 Jun 19;280(5371):1884-8. doi:10.1126/science.280.5371.1884; Stewart-Jones G.B.E., Soto C., Lemmin T., Chuang G.Y. et al. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. // Cell. 2016 May 5;165(4):813-26. doi:10.1016/j.cell.2016.04.010.; Walker L.M., Phogat S.K., Chan-Hui Po-Y., Wagner D. et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. // Science. 2009 Oct 9;326(5950):285-9. doi:10.1126/science.1178746.; Alam S.M., McAdams M., Boren D., Rak M. et al. The Role of Antibody Polyspecificity and Lipid Reactivity in Binding of Broadly Neutralizing Anti-HIV-1 Envelope Human Monoclonal Antibodies 2F5 and 4E10 to Glycoprotein 41 Membrane Proximal Envelope Epitopes. // J. Immunol. 2007 Apr 1;178(7):4424-35. doi:10.4049/jimmunol.178.7.4424.; Liao H.-X., Chen Xi, Munshaw S., Zhang R. et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. // J. Exp. Med. 2011 Oct 24;208(11):2237-49. doi:10.1084/jem.20110363.; Haynes B.F., Fleming J., Clair E.W.St. et al. Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies. // Science. 2005 Jun 24;308(5730):1906-8. doi:10.1126/science.1111781.; Matyas G.R., Beck Z., Karasavvas N., Alving C.R. Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1. // Biochim Biophys Acta. 2009 Mar;1788(3):660-5. doi:10.1016/j.bbamem.2008.11.015.; Barbas C.F. III, Björling E., Chiodi F., Dunlop N., Cababa D. et al. Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. // Proc. Natl. Acad. Sci. USA. 1992 Oct 1;89(19):9339-43. doi:10.1073/pnas.89.19.9339.; Burton D., Pyati J., Koduri R., Sharp S.J. et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. // Science. 1994 Nov 11;266(5187):1024-7. doi:10.1126/science.7973652.; Gorny M.K., Conley A.J., Karwowska S., Buchbinder A., Xu J.Y., Emini E.A., Koenig S., Zolla-Pazner S. Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody. // J. Virol. 1992 Vol. 66 (12). P. 7538-42. doi:10.1128/JVI.66.12.7538-7542.1992.; Muster T., Steindl F., Purtscher M., Trkola A., Klima A., Himmler G., Rüker F., Katinger H. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. // J. Virol. 1993 Nov;67(11):6642-7. doi:10.1128/JVI.67.11.6642-6647.1993.; Stiegler G., Kunert R., Purtscher M., Wolbank S., Voglauer R., Steindl F., Katinger H. A Potent Cross-Clade Neutralizing Human Monoclonal Antibody against a Novel Epitope on gp41 of Human Immunodeficiency Virus Type 1. // AIDS Res. Hum. Retroviruses. 2001 Dec 10;17(18):1757-65. doi:10.1089/08892220152741450.; Zwick M.B., Labrijn A.F., Wang M., Spenlehaueret C. et al. Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41. // J. Virol. 2001 Nov;75(22):10892-905. doi:10.1128/JVI.75.22.10892-10905.2001.; Wei X., Decker J.M., Wang S., Hui H. et al. Antibody neutralization and escape by HIV-1. // Nature. 2003 Mar 20;422(6929):307-12. doi:10.1038/nature01470.; Richman D.D., Wrin T., Little S.J., Petropoulos C.J. et al. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. // Proc. Natl. Acad. Sci. U. S. A. 2003 Apr 1;100(7):4144-9. doi:10.1073/pnas.0630530100.; Mascola J.R. and Haynes B.F. HIV-1 neutralizing antibodies: understanding nature’s pathways. // Immunol. Rev. 2013 Jul;254(1):225-44. doi:10.1111/imr.12075.; Rusert P., Kouyos R.D., Kadelka C., Ebner H. et al. Determinants of HIV-1 broadly neutralizing antibody induction. // Nat. Med. 2016 Nov;22(11):1260-1267. doi:10.1038/nm.4187.; Subbaraman H., Schanz M., Trkola A. Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy? // Retrovirology. 2018 Jul 28;15(1):52. doi:10.1186/s12977-018-0433-2.; Dugast A.-S., Arnold K., Lofano G., Moore S. et al. Virus-driven Inflammation Is Associated with the Development of bNAbs in Spontaneous Controllers of HIV. // Clin. Infect. Dis. 2017 Apr 15;64(8):1098-1104. doi:10.1093/cid/cix057.; Aasa-Chapman M.M., Hayman A., Newton P., Cornforth D. et al. Development of the antibody response in acute HIV-1 infection. // AIDS. 2004 Feb 20;18(3):371-81. doi:10.1097/00002030-200402200-00002.; Mikell I., Sather D.N., Kalams S.A., Altfeld M., Alter G., Stamatatos L. et al. Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1. // PLoS Pathog. 2011 Jan 13;7(1):e1001251. doi:10.1371/journal.ppat.1001251.; Landais E. and Moore P.L. Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers. // Retrovirology. 2018 Sep 5;15(1):61. doi:10.1186/s12977-018-0443-0.; Doria-Rose N.A., Schramm C.A., Gorman J., Moore P.L. et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. // Nature. 2014 May 1;509(7498):55-62. doi:10.1038/nature13036.; Klein F., Diskin R., Scheid J.F., Gaebler C. et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. // Cell. 2013 Mar 28;153(1):126-38. doi:10.1016/j.cell.2013.03.018.; Kepler T.B., Liao H.-X., Alam SM., Bhaskarabhatla R. et al. Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies. // Cell Host Microbe. 2014 Sep 10;16(3):304-13. doi:10.1016/j.chom.2014.08.006.; Wardemann H., Yurasov S., Schaefer A., Young J.W., Meffre E., Nussenzweig M.C. Predominant Autoantibody Production by Early Human B Cell Precursors. // Science. 2003 Sep 5;301(5638):1374-7. doi:10.1126/science.1086907.; Mouquet H., Scheid J.F., Zoller M.J., Krogsgaard M. et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. // Nature. 2010 Sep 30;467(7315):591-5. doi:10.1038/nature09385.; Diskin R., Scheid J.F., Marcovecchio P.M. et al. Increasing the Potency and Breadth of an HIV Antibody by using Structure-Based Rational Design. // Science. 2011 Dec 2;334(6060):1289-93. doi:10.1126/science.1213782.; Yang G., Holl TM., Liu Y., Li Y., Lu X. et al. Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. // J. Exp. Med. 2013 Feb 11;210(2):241-56. doi:10.1084/jem.20121977.; Scheid J.F., Mouquet H., Ueberheide B., Diskin R. et al. Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding. // Science. 2011 Sep 16;333(6049):1633-7. doi:10.1126/science.1207227.; Zhou P., Wang H., Fang M., Li Y. et al. Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies. // PLOS Pathog. 2019 Jun 13;15(6). P. e1007819. doi:10.1371/journal.ppat.1007819.; Asokan M., Rudicell R.S., Louder M., McKee K. et al. Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization. // J. Virol. 2015 Dec;89(24):12501-12. doi:10.1128/JVI.02097-15.; Wagh K., Seaman M.S., Zingg M., Fitzsimons T. et al. Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. // PLoS Pathog. 2018 Mar 5;14(3):e1006860. doi:10.1371/journal.ppat.1006860.; Xu L., Pegu A., Rao E., Doria-Rose N. et al. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. // Science. 2017 Oct 6;358(6359):85-90. doi:10.1126/science.aan8630.; Steinhardt J.J., Guenaga J., Turner H.L., McKee K. et al. Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity. // Nat. Commun. 2018 Feb 28;9(1):877. doi:10.1038/s41467-018-03335-4.; Ko S.-Y., Pegu A., Rudicell R.S., Yang Z.-y. et al. Enhanced neonatal Fc receptor function improves protection against primate SHIV infection. // Nature. 2014 Oct 30;514(7524):642-5. doi:10.1038/nature13612.; Gaudinski M.R., Coates E.E., Houser K.V., Chen G.L. et al. Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults. // PLoS Med. 2018 Jan 24;15(1):e1002493. doi:10.1371/journal.pmed.1002493.; Gautam R., Nishimura Y., Pegu A., Nason M.C. et al. A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges. // Nature 2016 May 5;533(7601):105-109. doi:10.1038/nature17677.; Simek M.D., Rida W., Priddy F.H., Pung P. et al. Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm. // J. Virol. 2009 Jul;83(14):7337-48. doi:10.1128/JVI.00110-09.; Binley J.M., Wrin T., Korber B., Zwick M.B. et al. Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies. // J. Virol. 2004 Dec;78(23):13232-52. doi:10.1128/JVI.78.23.13232-13252.2004.; Babcook J.S., Leslie K.B., Olsen O.A., Salmon R.A., Schrader J.W. A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities. // Proc. Natl. Acad. Sci. 1996 Jul 23;93(15):7843-8. doi:10.1073/pnas.93.15.7843.; Tiller T., Meffre E., Yurasov S., Tsuiji M., Nussenzweig M.C., Wardemann H. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. // J. Immunol. Methods. 2008 Jan 1;329(1-2):112-24. doi:10.1016/j.jim.2007.09.017.; West A.P., Scharf L., Scheid J.F., Klein F., Bjorkman P.J., Nussenzweig M.C. Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy. // Cell. 2014 Feb 13;156(4):633-48. doi:10.1016/j.cell.2014.01.052.; Wu X., Yang Z.Y., Li Y., et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1 // Science. 2010. Vol. 329 (5993). P. 856-861. DOI:10.1126/science.1187659; Rudicell R.S., Kwon Y.D., Ko S.Y., et al. Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo // J Virol. 2014. Vol. 88 (21). P. 12669-12682. DOI:10.1128/JVI.02213-14; Huang J., Kang B.H., Ishida E., et al. Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth // Immunity. 2016. Vol. 45 (5). P. 1108-1121. DOI:10.1016/j.immuni.2016.10.027; Julg B., Pegu A , Abbink P , et al. Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys // J Virol. 2017. Vol. 91 (16). P. e00498-17. DOI:10.1128/JVI.00498-17; Scheid J.F., Horwitz J.A., Bar-On Y., et al. HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption // Nature. 2016. Vol. 535 (7613). P. 556-560. DOI:10.1038/nature18929; Shingai M., Nishimura Y., Klein F., et al. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia // Nature. 2013. Vol. 503 (7475). P. 277-280. DOI:10.1038/nature12746; Nishimura Y., Gautam R., Chun T.W., et al. Early antibody therapy can induce long-lasting immunity to SHIV // Nature. 2017. Vol. 543 (7646). P. 559-563. DOI:10.1038/nature21435; Sajadi M.M., Dashti A., Rikhtegaran Tehrani Z., et al. Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses // Cell. 2018. Vol. 173 (7). P. 1783-1795. DOI:10.1016/j.cell.2018.03.061; Walker L.M., Huber M., Doores K.J., et al. Broad neutralization coverage of HIV by multiple highly potent antibodies // Nature. 2011. Vol. 477 (7365). P. 466-470. DOI:10.1038/nature10373; Mouquet H., Scharf L., Euler Z., et al. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies // Proc Natl Acad Sci U S A. 2012. Vol. 109(47). P. E3268-E3277. DOI:10.1073/pnas.1217207109; Sanders R.W., Derking R., Cupo A., et al. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies // PLoS Pathog. 2013. Vol. 9 (9). P. e1003618. DOI:10.1371/journal.ppat.1003618; Doria-Rose N.A., Bhiman J.N., Roark R.S., et al. New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency // J Virol. 2015. Vol. 90(1). P. 76-91. DOI:10.1128/JVI.01791-15; Sok D., van Gils M.J., Pauthner M., et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex // Proc Natl Acad Sci U S A. 2014. Vol. 111 (49). P. 17624-17629. DOI:10.1073/pnas.1415789111; Huang J., Ofek G., Laub L., et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody // Nature. 2012. Vol. 491 (7424). P. 406-412. DOI:10.1038/nature11544; Williams L.D., Ofek G., Schätzle S., et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma // Sci Immunol. 2017. Vol. 2 (7). P. eaal2200. DOI:10.1126/sciimmunol.aal2200; Wagh K., Bhattacharya T., Williamson C., et al. Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection // PLoS Pathog. 2016. Vol. 12 (3). P. e1005520. DOI:10.1371/journal.ppat.1005520; Julg B., Liu P.T., Wagh K., et al. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail // Sci Transl Med. 2017. Vol. 9 (408). P. eaao4235. DOI:10.1126/scitranslmed.aao4235; Pegu A., Hessell A.J., Mascola J.R., Haigwood N.L. Use of broadly neutralizing antibodies for HIV-1 prevention // Immunol Rev. 2017. Vol. 275 (1). P. 296-312. DOI:10.1111/imr.12511; Cavacini L.A., Samore M.H., Gambertoglio J., et al. Phase I study of a human monoclonal antibody directed against the CD4-binding site of HIV type 1 glycoprotein 120 // AIDS Res Hum Retroviruses. 1998. Vol. 14 (7). P. 545-550. DOI:10.1089/aid.1998.14.545; Caskey M., Klein F., Lorenzi J.C., et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 // Nature. 2015. Vol. 522 (7557). P. 487-491. DOI:10.1038/nature14411; Ledgerwood J.E., Coates E.E., Yamshchikov G., et al. Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults // Clin Exp Immunol. 2015. Vol. 182 (3). P. 289-301. DOI:10.1111/cei.12692; Caskey M., Schoofs T., Gruell H., et al. Antibody 10-1074 suppresses viremia in HIV-1-infected individuals // Nat Med. 2017. Vol. 23 (2). P. 185-191. DOI:10.1038/nm.4268; Lynch R.M., Boritz E., Coates E.E., et al. Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection // Sci Transl Med. 2015. Vol. 7 (319). P. 319ra206. DOI:10.1126/scitranslmed.aad5752; Bar K.J., Sneller M.C., Harrison L.J., et al. Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption // N Engl J Med. 2016. Vol. 375 (21). P. 2037-2050. DOI:10.1056/NEJMoa1608243; Mendoza P., Gruell H., Nogueira L., et al. Combination therapy with anti-HIV-1 antibodies maintains viral suppression // Nature. 2018. Vol. 561 (7724). P. 479-484. DOI:10.1038/s41586-018-0531-2; Niessl J., Baxter A.E., Mendoza P., et al. Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity // Nat Med. 2020. Vol. 26 (2). P. 222-227. DOI:10.1038/s41591-019-0747-1; Bar-On Y, Gruell H, Schoofs T, et al. Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals // Nat Med. 2018. Vol. 24 (11). P. 1701-1707. DOI:10.1038/s41591-018-0186-4; Mahomed S., Garrett N., Karim Q.A., et al. Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial // BMJ Open. 2020. Vol. 10 (11). P. e042247. DOI:10.1136/bmjopen-2020-042247; https://hiv.bmoc-spb.ru/jour/article/view/593

  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20