المؤلفون: Christophe Hirtz, Germain U. Busto, Karim Bennys, Jana Kindermans, Sophie Navucet, Laurent Tiers, Simone Lista, Jérôme Vialaret, Laure-Anne Gutierrez, Yves Dauvilliers, Claudine Berr, Sylvain Lehmann, Audrey Gabelle

المصدر: Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)

مصطلحات موضوعية: Alzheimer’s disease, Plasma, Biomarkers, IPMS, Simoa, Diagnosis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-9193

URL الوصول: https://doaj.org/article/6fc3f7aac5d146e7b75806a0e6a82b48

المؤلفون: Lisa Perus, Germain U. Busto, Jean-François Mangin, Emmanuelle Le Bars, Audrey Gabelle

المصدر: Frontiers in Aging Neuroscience, Vol 14 (2022)

مصطلحات موضوعية: nutrition, cognitive training, physical exercise, multidomain intervention, brain imaging, Alzheimer's disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.1014559/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/8f28bd8e1c0440fe96f182d4b9018658

المؤلفون: Ying Tan, Dinghui Yu, Germain U. Busto, Curtis Wilson, Ronald L. Davis

المصدر: Cell Reports, Vol 4, Iss 6, Pp 1082-1089 (2013)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713004312; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/470eee6b449b48edbac89bf1915cc17e

المؤلفون: Karim Bennys, Germain U. Busto, Jacques Touchon

المصدر: Research in Sports Medicine. :1-12

مصطلحات موضوعية: Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e0ba5c928b55ed0f1c14412aa7acaf56
https://doi.org/10.1080/15438627.2023.2189594

المؤلفون: Claire Marquilly, Germain U Busto, Brittany S Leger, Ana Boulanger, Edward Giniger, James A Walker, Lee G Fradkin, Jean-Maurice Dura

المصدر: PLoS Genetics, Vol 17, Iss 1, p e1009287 (2021)

مصطلحات موضوعية: Genetics, QH426-470

Relation: https://doi.org/10.1371/journal.pgen.1009287; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404; https://doaj.org/article/efc38108467142319cba47af0ac17410

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287
https://doaj.org/article/efc38108467142319cba47af0ac17410

المؤلفون: Lisa Perus, Germain U. Busto, Jean-François Mangin, Emmanuelle Le Bars, Audrey Gabelle

مصطلحات موضوعية: Neuroscience, Pathology, Health Care, Psychiatry (incl. Psychotherapy), Clinical Sciences not elsewhere classified, Central Nervous System, Aged Care Nursing, Aged Health Care, Protein Trafficking, nutrition, cognitive training, physical exercise, multidomain intervention, brain imaging, Alzheimer's disease, prevention, biomarkers

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Effects_of_preventive_interventions_on_neuroimaging_biomarkers_in_subjects_at-risk_to_develop_Alzheimer_s_disease_A_systematic_review_PDF/21616701

الاتاحة: https://doi.org/10.3389/fnagi.2022.1014559.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Effects_of_preventive_interventions_on_neuroimaging_biomarkers_in_subjects_at-risk_to_develop_Alzheimer_s_disease_A_systematic_review_PDF/21616701

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Structure_and_overexpression_of_the_Abl_protein_/13610272

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s002

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_loss_of_i_htt_i_rescues_the_i_Appl_i_sup_i_d_i_sup_MB_axon_outgrowth_mutant_phenotype_/13610284

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_htt_i_interaction_with_i_Abl_i_/13610278

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s004

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_Abl_i_loss_of_function_in_MBs_/13610275

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s003

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_overexpression_of_i_Abl_i_rescues_the_i_Appl_i_sup_i_d_i_sup_and_the_i_dsh_i_sup_i_1_i_sup_mutant_phenotypes_/13610269

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_loss_of_i_htt_i_rescues_the_i_dsh_i_sup_i_1_i_sup_MB_axon_outgrowth_mutant_phenotype_/13610287

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g002

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Detection_of_the_Abl-FRET_biosensor_in_the_MBs_/13610281

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s005

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Either_loss_or_overexpression_of_i_Abl_i_affect_MB_neuron_morphology_/13610290

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g003

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Reducing_i_htt_i_expression_increases_i_Abl_i_-FRET_biosensor_phosphorylation_state_during_MB_development_/13610296

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g005

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_htt_i_does_not_seem_to_affect_the_quantity_of_ABL_in_the_MBs_or_the_total_levels_of_neuronal_Abl_in_i_Drosophila_i_/13610299

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g006

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/dataset/_i_Abl_i_mutant_MARCM_clones_/13610305

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.t001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Htt_is_a_repressor_of_Abl_activity_required_for_Appl-induced_axonal_growth_/13610302

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g007

المؤلفون: Lee G. Fradkin, Jean-Maurice Dura, Brittany S. Leger, Ana Boulanger, Germain U. Busto, Claire Marquilly, James A. Walker, Edward Giniger

المساهمون: Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), St James University Hospital, Massachusetts General Hospital [Boston], Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], University of Massachusetts Medical School [Worcester] (UMASS), University of Massachusetts System (UMASS), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010)

المصدر: PLoS Genetics
PLoS Genetics, Public Library of Science, 2021, 17 (1), pp.e1009287. ⟨10.1371/journal.pgen.1009287⟩
PLoS Genetics, Vol 17, Iss 1, p e1009287 (2021)

مصطلحات موضوعية: Huntingtin, Mutant, Axonal Transport, 0302 clinical medicine, Animal Cells, Fluorescence Resonance Energy Transfer, Amyloid precursor protein, Axon, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Neurons, Huntingtin Protein, 0303 health sciences, ABL, Effector, Drosophila Melanogaster, Eukaryota, Polyglutamine tract, 3. Good health, Cell biology, Phenotypes, Huntington Disease, Spectrophotometry, Hyperexpression Techniques, Cellular Types, HTT, Embryonic Development, Repressor, 03 medical and health sciences, Alzheimer Disease, Memory, Genetics, Humans, Molecular Biology Techniques, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Mushroom Bodies, Molecular Biology Assays and Analysis Techniques, fungi, Organisms, Biology and Life Sciences, Invertebrates, nervous system, Mutation, Nerve Degeneration, Animal Studies, FRET, Acyltransferases, 030217 neurology & neurosurgery, Appl signaling, Neuroscience, Cloning, Developmental Biology, Cancer Research, Life Cycles, [SDV]Life Sciences [q-bio], QH426-470, Fluorophotometry, axonal growth, Amyloid beta-Protein Precursor, Nerve Fibers, Spectrum Analysis Techniques, Larvae, hemic and lymphatic diseases, Drosophila Proteins, Genetics (clinical), biology, Chemistry, Animal Models, Insects, medicine.anatomical_structure, Experimental Organism Systems, Mushroom bodies, Drosophila, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Drosophila melanogaster, Signal transduction, Signal Transduction, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Arthropoda, Research and Analysis Methods, Model Organisms, mental disorders, Gene Expression and Vector Techniques, medicine, Animals, Learning, Kinase activity, 030304 developmental biology, Cell Biology, biology.organism_classification, mushroom body, Axons, Cellular Neuroscience, biology.protein, Zoology, Entomology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64396ad1ad999b4c6e36846bd94293a
https://hal.archives-ouvertes.fr/hal-02401010/document

المؤلفون: Jae-Yoon Jung, Ronald L. Davis, Germain U. Busto, Tugba Guven-Ozkan, Ilaria Drago

المصدر: eNeuro

مصطلحات موضوعية: Untranslated region, microRNA, memory suppressor gene, General Neuroscience, Mutant, HEK 293 cells, General Medicine, Biology, kinesin heavy chain, Cell biology, Cognition and Behavior, Gene expression, Mushroom bodies, Memory consolidation, Luciferase, Research Article: New Research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2d0dc0bff91fe40c80be107cc30d1c
https://doi.org/10.1523/eneuro.0224-20.2020