المؤلفون: Melita Kaltak, Petra de Bruijn, Willemijn van Leeuwen, Gerard Platenburg, Frans P. M. Cremers, Rob W. J. Collin, Jim Swildens

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/60dfc9994f29491fbe23cd17aa346c9d

المؤلفون: Melita Kaltak, Rocio Blanco-Garavito, Laurie L. Molday, Claire-Marie Dhaenens, Eric E. Souied, Gerard Platenburg, Jim Swildens, Robert S. Molday, Frans P. M. Cremers

المصدر: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1479-5876

URL الوصول: https://doaj.org/article/cddd2e0c77e44ce5a473e43acb5cf400

المؤلفون: Melita Kaltak, Petra de Bruijn, Davide Piccolo, Sang-Eun Lee, Kalyan Dulla, Thomas Hoogenboezem, Wouter Beumer, Andrew R. Webster, Rob W.J. Collin, Michael E. Cheetham, Gerard Platenburg, Jim Swildens

المصدر: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 674-688 (2023)

مصطلحات موضوعية: MT: Oligonucleotides: Therapies and Applications, RNA therapy, antisense oligonucleotides, Stargardt disease, splicing correction, retinal organoids, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123000409; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/40b153ac34224120aa4a8a2cd3c85817

المؤلفون: Wouter Beumer, Jim Swildens, Teresinha Leal, Sabrina Noel, Herma Anthonijsz, Geert van der Horst, Hester Kuiperij-Boersma, Marko Potman, Charlotte van Putten, Patricia Biasutto, Gerard Platenburg, Hugo de Jonge, Noreen Henig, Tita Ritsema

المصدر: PLoS ONE, Vol 14, Iss 6, p e0219182 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/998648464a6246f1ba96ae9e7ad7986f

المؤلفون: Karlijn L. Kooij, Mieneke C.M. Luijendijk, Lisa Drost, Gerard Platenburg, Annemarie van Elburg, Roger A.H. Adan

المصدر: European Neuropsychopharmacology. 71:65-74

مصطلحات موضوعية: Pharmacology, Psychiatry and Mental health, Neurology, Pharmacology (medical), Neurology (clinical), Biological Psychiatry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8e3fdcf9fa60dc540149367f4fea0c8
https://doi.org/10.1016/j.euroneuro.2023.03.008

المؤلفون: Melita Kaltak, Petra de Bruijn, Davide Piccolo, Sang-Eun Lee, Kalyan Dulla, Thomas Hoogenboezem, Wouter Beumer, Andrew R. Webster, Rob W.J. Collin, Michael E. Cheetham, Gerard Platenburg, Jim Swildens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a242d1e2c65466724a63f4654c95a121
https://doi.org/10.1101/2022.08.12.503728

المؤلفون: Gerard Platenburg, Jingjing Zang, Erwin van Wijk, Margo Dona, Sanne Broekman, Jiayi Miao, Cathaline den Besten, Erik de Vrieze, Hee Lam Chan, Janne J. Turunen, Hanka Venselaar, Lars Vorthoren, Kalyan Dulla, Peter Adamson, Ralph Slijkerman, Stephan C.F. Neuhauss, Silvia Albert, Wouter Beumer, Theo A. Peters, Iris Schmidt, Hester van Diepen, Ronald J.E. Pennings, Hannie Kremer, Levi Buil, Iris Schulkens

المصدر: Molecular Therapy, 29, 8, pp. 2441-2455
Mol Ther
Molecular Therapy, 29, 2441-2455

مصطلحات موضوعية: Models, Molecular, Usher syndrome, Mutant, Induced Pluripotent Stem Cells, Biology, medicine.disease_cause, Retina, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], 03 medical and health sciences, Exon, Mice, 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, Drug Discovery, Retinitis pigmentosa, otorhinolaryngologic diseases, Genetics, medicine, Animals, Humans, Outer nuclear layer, Molecular Biology, Zebrafish, Cells, Cultured, 030304 developmental biology, Pharmacology, 0303 health sciences, Mutation, Extracellular Matrix Proteins, Dose-Response Relationship, Drug, Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16], Exons, Oligonucleotides, Antisense, Zebrafish Proteins, medicine.disease, biology.organism_classification, Molecular biology, Exon skipping, Disease Models, Animal, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Commentary, Molecular Medicine, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Retinitis Pigmentosa

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0009073ca7e61b8b3ea940e0d6aa4cb9
https://hdl.handle.net/1887/3627509

المؤلفون: Stephen R. Russell, Arlene V. Drack, Artur V. Cideciyan, Samuel G. Jacobson, Bart P. Leroy, Caroline Van Cauwenbergh, Allen C. Ho, Alina V. Dumitrescu, Ian C. Han, Mitchell Martin, Wanda L. Pfeifer, Elliott H. Sohn, Jean Walshire, Alexandra V. Garafalo, Arun K. Krishnan, Christian A. Powers, Alexander Sumaroka, Alejandro J. Roman, Eva Vanhonsebrouck, Eltanara Jones, Fanny Nerinckx, Julie De Zaeytijd, Rob W. J. Collin, Carel Hoyng, Peter Adamson, Michael E. Cheetham, Michael R. Schwartz, Wilhelmina den Hollander, Friedrich Asmus, Gerard Platenburg, David Rodman, Aniz Girach

المصدر: Nature Medicine, 28, 1014-1021
NATURE MEDICINE
Nature Medicine, 28, 5, pp. 1014-1021

مصطلحات موضوعية: Adult, Leber Congenital Amaurosis, Cell Cycle Proteins, General Medicine, Oligonucleotides, Antisense, Blindness, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], General Biochemistry, Genetics and Molecular Biology, Cytoskeletal Proteins, Antigens, Neoplasm, Medicine and Health Sciences, Humans, Child, Vision, Ocular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547b93068a0384a77df09d77369a5f9a
https://pubmed.ncbi.nlm.nih.gov/35379979

المؤلفون: Hironori Adachi, Jonathan Chen, Bart Klein, Gerard Platenburg, Pedro Morais, Yi-Tao Yu

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5f6ead8169467950b88fe0626d0351e
https://doi.org/10.2139/ssrn.3988395

المؤلفون: Patricia Biasutto, Alejandro J. Roman, Magali Taiel, Michael E. Cheetham, Julie De Zaeytijd, Artur V. Cideciyan, Ian C. Han, Michael R. Schwartz, Alexandra V. Garafalo, David M. Rodman, Maria D. Tome, Alexander Sumaroka, Arlene V. Drack, Wilma de Wit, Irina Balikova, Allen C. Ho, Stephen R. Russell, Fanny Nerinckx, Peter Adamson, Caroline Van Cauwenbergh, Wanda L. Pfeifer, Maria D. Hochstedler, Bart P. Leroy, Samuel G. Jacobson, Elliott H. Sohn, Gerard Platenburg, Jason Charng

المصدر: Nature Medicine. 25:225-228

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Visual acuity, genetic structures, Oligonucleotide, business.industry, Childhood blindness, General Medicine, medicine.disease, Ciliopathies, eye diseases, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Ciliopathy, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Ophthalmology, RNA splicing, medicine, medicine.symptom, Allele, business, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b0deebfc45ec4119fb909d39e35b3b88
https://doi.org/10.1038/s41591-018-0295-0

المؤلفون: Alexandra V. Garafalo, Allen C. Ho, Alina V. Dumitrescu, David M. Rodman, Rob W.J. Collin, Carel B. Hoyng, Wanda L. Pfeifer, Mitchell Martin, Arun kumar Krishnan, Julie De Zaeytijd, Bart P. Leroy, Eva Vanhonsebrouck, Aniz Girach, Alejandro J. Roman, Stephen R. Russell, Wilhelmina den Hollander, Gerard Platenburg, Ian C. Han, Fanny Nerinckx, Arlene V. Drack, Christian A. Powers, Friedrich Asmus, Jean Walshire, Samuel G. Jacobson, Caroline Van Cauwenbergh, Elliott H. Sohn, Artur V. Cideciyan, Eltanara A Jones, Michael R. Schwartz, Michael E. Cheetham, Peter Adamson, Alexander Sumaroka

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: medicine.medical_specialty, Visual acuity, business.industry, Institutional review board, Leber congenital amaurosis, medicine.disease, Informed consent, Internal medicine, Good clinical practice, Clinical endpoint, Medicine, In patient, medicine.symptom, business, Macular edema

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e5c6599cf65265e47b2d40ae139cd64e
https://doi.org/10.2139/ssrn.3745122

المؤلفون: Verena Wally, Douglas R. Keene, M. Peter Marinkovich, Sara F. Tufa, Eva M. Murauer, Elisabeth M. Haisma, Alexander Nyström, Ulrich Koller, Dimitra Kiritsi, Pauline Nauroy, Marieke Hogervorst, Olivier Bornert, Stefan Hainzl, Gerard Platenburg, Ingrid Hausser, Tita Ritsema, Ioannis Athanasiou, Jim Swildens, Johannes Bischof

المصدر: The Journal of investigative dermatology. 141(4)

مصطلحات موضوعية: 0301 basic medicine, Keratinocytes, Collagen Type VII, Biopsy, Primary Cell Culture, Mice, Transgenic, Dermatology, Biochemistry, Cell Line, 03 medical and health sciences, Exon, Mice, 0302 clinical medicine, Fibrosis, Medicine, Animals, Humans, Molecular Biology, Gene, Dermoepidermal junction, Skin, Wound Healing, integumentary system, business.industry, Wild type, Cell Biology, Exons, Genetic Therapy, Fibroblasts, Oligonucleotides, Antisense, medicine.disease, Exon skipping, Epidermolysis Bullosa Dystrophica, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, Cancer research, business, Wound healing, Keratinocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf86473d755768081844e5cb869d787
https://pubmed.ncbi.nlm.nih.gov/32946877

المؤلفون: Gerard Platenburg, Willeke M. C. van Roon-Mom, Herma Anthonijsz, Hyeongju Kim, Lodewijk J.A. Toonen, Nicholas S. Caron, Levi Buil, Michael R. Hayden, Zhana Karneva, Geert van der Horst, Frits van der Ham, Linda M. van der Graaf, Pontus Klein, Wouter Beumer, Ji-Joon Song

المصدر: Experimental therapeutics – preclinical.

مصطلحات موضوعية: Gene isoform, congenital, hereditary, and neonatal diseases and abnormalities, Messenger RNA, Pathology, medicine.medical_specialty, Huntingtin, Chemistry, Mutant, Wild type, Cleavage (embryo), Phenotype, In vitro, nervous system, mental disorders, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e5fa5570ed52547349af2c57b84d5030
https://doi.org/10.1136/jnnp-2018-ehdn.237

المؤلفون: Manley Huang, Dan Chen, Roanna Ueda, Yifan Mao, Carole Kurahara, Fiona A. Harding, Gerard Platenburg, Namrata Patil

المصدر: European Journal of Immunology. 33:172-182

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Genetically modified mouse, Transgene, Immunology, Antigen-Presenting Cells, Gene Expression, CD11c, Mice, Transgenic, Thymus Gland, Human leukocyte antigen, Biology, medicine.disease_cause, Autoimmune Diseases, Autoimmunity, Mice, HLA-DR3 Antigen, Antigen, HLA-DQ Antigens, medicine, Animals, Humans, Immunology and Allergy, RNA, Messenger, Antigens, Antigen processing, Flow Cytometry, Molecular biology, Immunoglobulin class switching, Models, Animal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9912aa2a955ae82ea936c606625c91
https://doi.org/10.1002/immu.200390020

المؤلفون: P.M. Marinkovich, M. Schuijt, M. Potman, N. Nguyen, I. Haisma, Tita Ritsema, L. van Wissen, S. Mahakena, Gerard Platenburg, K.J. Shridhar

المصدر: Journal of Investigative Dermatology. 137:S226

مصطلحات موضوعية: Messenger RNA, Exon, Anti sense oligonucleotide, Chemistry, Cell Biology, Dermatology, Molecular Biology, Biochemistry, Molecular biology, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c10c7708f87f75270dbf61ce1c4f9be1
https://doi.org/10.1016/j.jid.2017.07.191

المؤلفون: Anita Dekker, De Wit Ineke, P. David Toman, R. Berg, Gerard Platenburg, Erika Platenburg, Naomi Sakai, Frank Pieper, Karatzas Costas N, Caroline Samuel, G. Daniels

المصدر: Transgenic Research. 8:415-427

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, Transgene, Structural gene, Lysine, Biology, Molecular biology, law.invention, Procollagen peptidase, Endocrinology, law, Internal medicine, Gene expression, Genetics, Recombinant DNA, medicine, Animal Science and Zoology, Agronomy and Crop Science, Biotechnology, Triple helix

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::724befd048db29e7c6b4fd79879e8022
https://doi.org/10.1023/a:1008959924856

المؤلفون: Monique Rijnkels, Jan H. Nuijens, P M Kooiman, de Boer Ha, van Dixhoorn M, Frank Pieper, Gerard Platenburg

المصدر: Transgenic Research. 7:5-14

مصطلحات موضوعية: Genetically modified mouse, Ratón, Transgene, Biology, Molecular biology, law.invention, law, Casein, Gene expression, Genetics, Recombinant DNA, Cosmid, Animal Science and Zoology, Agronomy and Crop Science, Gene, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::537b823919980463843a05ee9314c230
https://doi.org/10.1023/a:1008892720466

المؤلفون: Erika P. A. Kootwijk, Karatzas Costas N, Gerard Platenburg, Rein Strijker, Herman A. de Boer, Ellen J. Vollebregt

المصدر: Transgenic Research. 5:421-431

مصطلحات موضوعية: Genetically modified mouse, DNA-Cytosine Methylases, Transcription, Genetic, Transgene, Genetic Vectors, Restriction Mapping, Mice, Transgenic, Biology, Mice, Mammary Glands, Animal, Complementary DNA, Gene expression, Genetics, Animals, Lactation, Gene, Binding Sites, Lactoferrin, Caseins, Methylation, DNA Methylation, Molecular biology, Gene Expression Regulation, DNA methylation, biology.protein, Cattle, Female, Animal Science and Zoology, Agronomy and Crop Science, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b25e42cbbbbb1c5ed3b707cd6c3a9a
https://doi.org/10.1007/bf01980207

المؤلفون: Gerard Platenburg, Cornelis J. M. Melief, Marieke F. Fransen, Suzanne van Duikeren, Willem-Jan Krebber, Ferry Ossendorp, Ramon Arens, Anke Redeker, Brigitte Wieles

المصدر: Journal of Immunology, 189(7), 3397-3403

مصطلحات موضوعية: T cell, Injections, Subcutaneous, Papillomavirus E7 Proteins, Immunology, Molecular Sequence Data, Uterine Cervical Neoplasms, Biology, CD8-Positive T-Lymphocytes, Cancer Vaccines, Mice, Mice, Congenic, Predictive Value of Tests, medicine, Tumor Cells, Cultured, Immunology and Allergy, Cytotoxic T cell, Animals, Amino Acid Sequence, Human papillomavirus 16, Effector, Cancer, Viral Vaccines, medicine.disease, Vaccination, Mice, Inbred C57BL, medicine.anatomical_structure, Cancer cell, Tumor necrosis factor alpha, Female, Immunologic Memory, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4146f480cc109e2b87d43602d33dc2
https://hdl.handle.net/1887/98224

المؤلفون: Paul Krimpenfort, Adriana Rademakers, Will Eyestone, Adriaan van der Schans, Sandra van den Broek, Patricia Kooiman, Erika Kootwijk, Gerard Platenburg, Frank Pieper, Rein Strijker, Herman de Boer

المصدر: Nature Biotechnology. 9:844-847

مصطلحات موضوعية: Transgene, Restriction Mapping, Biomedical Engineering, Bioengineering, Biology, Transfection, Applied Microbiology and Biotechnology, Animals, Genetically Modified, Andrology, Embryonic and Fetal Development, Pregnancy, Animals, Humans, Microinjection, Cells, Cultured, Dairy cattle, Southern blot, Genetics, Caseins, Embryo, DNA, Embryo Transfer, Embryo transfer, Genetically modified organism, Blot, Blotting, Southern, Lactoferrin, Oocytes, Molecular Medicine, Cattle, Female, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea8d7bf9e882f9c8947d69f82af452f
https://doi.org/10.1038/nbt0991-844