-
1Academic Journal
المؤلفون: Eric J. Thompson, Ashok Gupta, George A. Vielhauer, John W. Regan, G. Tim Bowden
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 402-410 (2001)
مصطلحات موضوعية: COX-1, COX-2, PGE2, EP1, tumor progression, keratinocyte growth, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
-
2
المؤلفون: Sid Ganguly, Soumen Paul, Joseph McGuirk, Jonathan D. Mahnken, Brea Lipe, Maegan L. Capitano, Dennis Allin, Hal E. Broxmeyer, Amanda L. Wise, Leyla Shune, Anurag K. Singh, Sunil Abhyankar, Abigale Berry, George A. Vielhauer, Mary J. Laughlin, Omar S. Aljitawi, Christopher Lominska, Tara L. Lin, Avishek Ganguly, Amy Cantilena
المصدر: Blood. 128:3000-3010
مصطلحات موضوعية: 0301 basic medicine, education.field_of_study, Umbilical Cord Blood Transplantation, business.industry, Immunology, Population, Cell Biology, Hematology, Cord Blood Stem Cell Transplantation, Biochemistry, Erythropoietin receptor, 03 medical and health sciences, Haematopoiesis, fluids and secretions, 030104 developmental biology, Erythropoietin, embryonic structures, medicine, Cancer research, Progenitor cell, education, business, medicine.drug, Homing (hematopoietic)
-
3
المؤلفون: Rick T. Dobrowsky, Brian S. J. Blagg, Jeffrey M. Holzbeierlein, George A. Vielhauer, Gaurav Garg, Heather E. Shinogle, Suman Ghosh
المصدر: ACS Chemical Biology
مصطلحات موضوعية: Gene isoform, Protein Folding, Biochemistry, Cell Line, Cell Movement, Extracellular, medicine, Humans, Protein Isoforms, HSP90 Heat-Shock Proteins, Novobiocin, biology, Cell migration, General Medicine, Articles, Hsp90, Cell biology, Gene Expression Regulation, Cytoplasm, Cell culture, Apoptosis, biology.protein, Molecular Medicine, medicine.drug, Molecular Chaperones, Protein Binding
-
4
المؤلفون: Iman Jokar, Kristi L. Neufeld, Maged Zeineldin, Derek Jensen, George A. Vielhauer, Nikhil K. Parelkar, Smita R. Paranjape
المصدر: Genetics. 197:1365-1376
مصطلحات موضوعية: Genotype, Carcinogenesis, Nonsense-mediated decay, Mice, Nude, Investigations, Biology, medicine.disease_cause, Group II Phospholipases A2, Mice, Plasmid, Genetics, medicine, Animals, Humans, RNA, Messenger, Cloning, Molecular, Allele, Promoter Regions, Genetic, Alleles, Polymorphism, Genetic, RNA, HCT116 Cells, Xenograft Model Antitumor Assays, In vitro, Nonsense Mediated mRNA Decay, Intestines, Human cancer, Plasmids
-
5
المؤلفون: Joseph McGuirk, Jeffrey D. Eskew, Jonathan D. Mahnken, Hal E. Broxmeyer, Nikhil K. Parelkar, George A. Vielhauer, Jeff Radel, Yinghua Xiao, Omar S. Aljitawi, Megan Swink, Bruce F. Kimler, Tara L. Lin
المصدر: Blood Cells, Molecules, and Diseases. 52:59-67
مصطلحات موضوعية: Graft Rejection, Pathology, medicine.medical_specialty, Myeloid, Transplantation, Heterologous, B-Lymphocyte Subsets, Gene Expression, Antigens, CD34, Bone Marrow Cells, Mice, Inbred Strains, Cord Blood Stem Cell Transplantation, Umbilical cord, Article, Progenitor Cell Engraftment, Andrology, Mice, Genes, Reporter, medicine, Animals, Humans, Luciferases, Molecular Biology, Hyperbaric Oxygenation, Umbilical Cord Blood Transplantation, business.industry, Graft Survival, Cell Biology, Hematology, Transplantation, medicine.anatomical_structure, Injections, Intravenous, Molecular Medicine, Female, Bone marrow, business, Spleen, Whole-Body Irradiation, Ex vivo
-
6
المؤلفون: Peter S. N. Rowe, Yan Hong, George A. Vielhauer, Jeff Eskew, Priyanka Bhamidi, Ossama Tawfik, Rama Garimella, H. Clarke Anderson
المصدر: Journal of Bone Oncology
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Osteosarcoma, business.industry, Extra-cellular membrane vesicles, Malignancy, medicine.disease, Preclinical, Metastasis, RUNX2, Orthotopic, Oncology, In vivo, Tumor progression, Cancer research, medicine, Histopathology, Bioluminescent, business, Myofibroblasts, Myofibroblast, Research Article
-
7
المؤلفون: Jeffrey M. Holzbeierlein, Brian S. J. Blagg, Laura B. Peterson, Huiping Zhao, George A. Vielhauer, Bhaskar Reddy Kusuma
المصدر: Journal of Medicinal Chemistry. 54:6234-6253
مصطلحات موضوعية: Aminocoumarins, Stereochemistry, Dimer, Antineoplastic Agents, Stereoisomerism, Article, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Heat shock protein, Drug Discovery, Humans, Structure–activity relationship, HSP90 Heat-Shock Proteins, biology, Combinatorial chemistry, Hsp90, Small molecule, Coumermycin A1, chemistry, SKBR3, Drug Design, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Protein Multimerization, Dimerization
-
8
المؤلفون: Jeffrey M. Holzbeierlein, Brian S. J. Blagg, Roger A. Rajewski, Douglas Brown, Gary E. L. Brandt, George A. Vielhauer, Alison C. Donnelly, Mark S. Cohen, Huiping Zhao, Bhaskar Reddy Kusuma
المصدر: Journal of Medicinal Chemistry. 54:3839-3853
مصطلحات موضوعية: Male, Carbohydrates, Antineoplastic Agents, DNA gyrase, Article, Hsp90 inhibitor, Structure-Activity Relationship, chemistry.chemical_compound, Coumarins, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Structure–activity relationship, HSP90 Heat-Shock Proteins, Molecular Targeted Therapy, Novobiocin, Cell Proliferation, Natural product, Molecular Structure, Cell growth, Cancer, medicine.disease, Anti-Bacterial Agents, chemistry, Biochemistry, Cell culture, Drug Design, Molecular Medicine, Female, medicine.drug
-
9
المؤلفون: Melinda Broward, William M. Robertson, Irene Dunwiddie, James P. Lajiness, Scott Weir, George A. Vielhauer, Dale L. Boger
المصدر: Journal of Medicinal Chemistry. 53:7731-7738
مصطلحات موضوعية: Steric effects, Indoles, Stereochemistry, Cleavage (embryo), Article, Duocarmycins, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Phenols, Nucleophile, In vivo, Drug Discovery, Animals, Phenol, Prodrugs, Pyrroles, Leukemia L1210, Antineoplastic Agents, Alkylating, Duocarmycin, Stereoisomerism, Prodrug, In vitro, chemistry, Mice, Inbred DBA, Molecular Medicine, Drug Screening Assays, Antitumor, Neoplasm Transplantation
-
10
المؤلفون: Joseph A. Burlison, Donna J. Lubbers, Brian S. J. Blagg, George A. Vielhauer, Jeffrey M. Holzbeierlein, Christopher Avila
المصدر: The Journal of Organic Chemistry. 73:2130-2137
مصطلحات موضوعية: Antineoplastic Agents, DNA gyrase, Structure-Activity Relationship, chemistry.chemical_compound, Prenylation, Cell Line, Tumor, medicine, Humans, HSP90 Heat-Shock Proteins, Enzyme Inhibitors, Novobiocin, chemistry.chemical_classification, Natural product, biology, Organic Chemistry, Cancer, medicine.disease, Enzyme, chemistry, Biochemistry, Cell culture, Enzyme inhibitor, Benzamides, biology.protein, Drug Screening Assays, Antitumor, Dimerization, medicine.drug
-
11
المؤلفون: Suman Ghosh, Douglas Brown, Brian S. J. Blagg, Eugene K. Lee, Jeffrey M. Holzbeierlein, Huiping Zhao, Weiya Liu, George A. Vielhauer
مصطلحات موضوعية: Male, Antineoplastic Agents, Plasma protein binding, Protein degradation, Heat Shock Protein Inhibitor, Hsp90 inhibitor, Prostate cancer, Western blot, Coumarins, Cell Line, Tumor, medicine, Humans, HSP90 Heat-Shock Proteins, Cell Proliferation, Pharmacology, biology, medicine.diagnostic_test, Phenylurea Compounds, HSC70 Heat-Shock Proteins, Cancer, Prostatic Neoplasms, Articles, medicine.disease, Hsp90, Molecular biology, Gene Expression Regulation, Neoplastic, biology.protein, Molecular Medicine, Novobiocin, Protein Binding
-
12
المؤلفون: George A. Vielhauer, Hiromichi Fujino, John W. Regan
المصدر: Journal of Biological Chemistry. 279:43386-43391
مصطلحات موضوعية: Cell signaling, Recombinant Fusion Proteins, T cell, Receptors, Prostaglandin, Prostaglandin, Biology, Dinoprost, Kidney, Transfection, Biochemistry, Dinoprostone, Cell Line, chemistry.chemical_compound, Genes, Reporter, medicine, Humans, Prostaglandin E2, Inositol phosphate, Receptor, Molecular Biology, beta Catenin, chemistry.chemical_classification, Cell Biology, Cell biology, Cytoskeletal Proteins, Protein Subunits, medicine.anatomical_structure, chemistry, Second messenger system, Trans-Activators, Signal transduction, Signal Transduction, medicine.drug
-
13
المؤلفون: Jinbo Zhao, Patrick T. Grogan, Brian S. J. Blagg, Jessica Ann Hall, Chitra Subramanian, Huiping Zhao, Joseph Bazzill, George A. Vielhauer, Eileen R. Brandes, Mark S. Cohen, Douglas Brown
المصدر: MedChemComm. 5(9)
مصطلحات موضوعية: Pharmacology, biology, Stereochemistry, Organic Chemistry, Triazole, Pharmaceutical Science, Protein degradation, Coumarin, Biochemistry, Combinatorial chemistry, Hsp90, Article, chemistry.chemical_compound, chemistry, SKBR3, Drug Discovery, Side chain, biology.protein, medicine, Molecular Medicine, Heat shock, Novobiocin, medicine.drug
-
14
المؤلفون: Shane R. Stecklein, Roy A. Jensen, Soumen Paul, Nikhil K. Parelkar, Biswarup Saha, Pratik Home, Iman Jokar, Ganeshkumar Rajendran, George A. Vielhauer, Ossama Tawfik, Marsha Danley, Sumedha Gunewardena, Soma Ray, Arindam Paul
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Lung Neoplasms, Estrogen receptor, Mice, Nude, Triple Negative Breast Neoplasms, Mice, SCID, Metastasis, Mice, Breast cancer, Mice, Inbred NOD, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Epidermal growth factor receptor, skin and connective tissue diseases, Molecular Biology, Triple-negative breast cancer, Protein Kinase C, Cell Proliferation, Original Paper, biology, Cancer, Cell Biology, Gene signature, medicine.disease, Isoenzymes, Cancer research, biology.protein, Female, Neoplasm Transplantation, Signal Transduction
-
15
المؤلفون: G. Tim Bowden, John W. Regan, Ashok Gupta, George A. Vielhauer, Eric J. Thompson
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 402-410 (2001)
مصطلحات موضوعية: Keratinocytes, Cancer Research, Skin Neoplasms, medicine.medical_treatment, tumor progression, medicine.disease_cause, Immunoenzyme Techniques, Mice, chemistry.chemical_compound, 0302 clinical medicine, Tumor Cells, Cultured, Receptor, Mice, Inbred BALB C, 0303 health sciences, biology, Reverse Transcriptase Polymerase Chain Reaction, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Receptors, Prostaglandin E, EP1 Subtype, 3. Good health, Isoenzymes, 030220 oncology & carcinogenesis, lipids (amino acids, peptides, and proteins), PGE2, Cell Division, Research Article, Signal Transduction, Prostaglandin E, medicine.medical_specialty, Prostaglandin E2 receptor, Blotting, Western, Mice, Nude, Prostaglandin, lcsh:RC254-282, Dinoprostone, 03 medical and health sciences, keratinocyte growth, Internal medicine, medicine, Animals, Receptors, Prostaglandin E, EP1, DNA Primers, 030304 developmental biology, COX-1, Membrane Proteins, COX-2, medicine.disease, Endocrinology, chemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Tumor progression, Cyclooxygenase 1, Cancer research, biology.protein, Cyclooxygenase, Skin cancer, Carcinogenesis, Receptors, Prostaglandin E, EP4 Subtype
-
16
المؤلفون: Jeffery M. Holzbeierlein, Bhaskar Reddy Kusuma, Wen Gu, George A. Vielhauer, Douglas Brown, Brian S. J. Blagg, Weiya Liu, Anuj Khandelwal
المصدر: Bioorganicmedicinal chemistry. 22(4)
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Plasma protein binding, Naphthalenes, Biochemistry, Article, chemistry.chemical_compound, Coumarins, Cell Line, Tumor, Drug Discovery, medicine, Humans, HSP90 Heat-Shock Proteins, Molecular Biology, Novobiocin, Biological evaluation, Cell Proliferation, biology, Chemistry, Cell growth, Organic Chemistry, Quinoline, Coumarin, Hsp90, Cell culture, biology.protein, MCF-7 Cells, Quinolines, Molecular Medicine, medicine.drug, Protein Binding
-
17
المؤلفون: Jeffrey M. Holzbeierlein, Robert L. Matts, Brian S. J. Blagg, Takrima Sadikot, Jeffrey D. Eskew, Megan Swink, Huiping Zhao, Bhaskar Reddy Kusuma, Roger A. Rajewski, Douglas Brown, George A. Vielhauer
مصطلحات موضوعية: Protein Denaturation, Reticulocytes, Blotting, Western, Antineoplastic Agents, Protein degradation, Protein Refolding, Small Molecule Libraries, Cell Line, Tumor, Drug Discovery, High-Throughput Screening Assays, Cancer screening, medicine, Animals, Humans, Luciferase, HSP90 Heat-Shock Proteins, Enzyme Inhibitors, Coloring Agents, Luciferases, Novobiocin, biology, Dose-Response Relationship, Drug, Rhodamines, Original Articles, Hsp90, Blot, Biochemistry, Cancer cell, biology.protein, Molecular Medicine, Biological Assay, Rabbits, medicine.drug
-
18
المؤلفون: Nikhil K. Parelkar, Douglas Brown, Dale L. Boger, George A. Vielhauer, Katharine K. Duncan, Amanda L. Wolfe
مصطلحات موضوعية: Indoles, Alkylation, Stereochemistry, Cell Survival, Chemistry, Pharmaceutical, Stereoisomerism, Article, chemistry.chemical_compound, Duocarmycins, Mice, Nucleophile, In vivo, Cell Line, Tumor, Drug Discovery, Potency, Phenol, Animals, Prodrugs, Leukemia L1210, Duocarmycin, Chromatography, High Pressure Liquid, Cell Proliferation, Antibiotics, Antineoplastic, Chemistry, DNA, Prodrug, Xenograft Model Antitumor Assays, Cell Hypoxia, Pyrrolidinones, Delayed-Action Preparations, Molecular Medicine, Indicators and Reagents, Spectrophotometry, Ultraviolet
-
19
المؤلفون: Amanda L. Wolfe, George A. Vielhauer, Nikhil K. Parelkar, Dale L. Boger, Megan Swink, James P. Lajiness
مصطلحات موضوعية: Cancer Research, Indoles, Lung Neoplasms, Cell Survival, Mice, Nude, Antineoplastic Agents, Apoptosis, Pharmacology, chemistry.chemical_compound, Mice, In vivo, Cell Line, Tumor, Cytotoxic T cell, Medicine, Animals, Humans, Prodrugs, Cytotoxicity, Duocarmycin, Cell Proliferation, Cell growth, business.industry, Cancer, Biological activity, Cell Cycle Checkpoints, Prodrug, medicine.disease, Xenograft Model Antitumor Assays, Oncology, chemistry, Molecular Medicine, Carbamates, business, Oxidation-Reduction, Research Paper
-
20
المؤلفون: Nikhil K. Parelkar, Amanda L. Wolfe, Scott Weir, Katharine K. Duncan, Dale L. Boger, George A. Vielhauer
مصطلحات موضوعية: Drug, Cyclopropanes, Carbamate, Indoles, medicine.medical_treatment, media_common.quotation_subject, Antineoplastic Agents, Article, Hydrolysis, chemistry.chemical_compound, Duocarmycins, Inhibitory Concentration 50, Mice, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Organic chemistry, Animals, Humans, Prodrugs, Free drug, Duocarmycin, media_common, Chemistry, Prodrug, Xenograft Model Antitumor Assays, Pyrrolidinones, Drug Design, Toxicity, Molecular Medicine, Carbamates
Full Text Finder