المؤلفون: Gentaroh Suzuki, Hiroko Kawagoe-Takaki, Takao Inoue, Toshifumi Kimura, Hirohiko Hikichi, Takashi Murai, Akio Satow, Mikiko Hata, Shunsuke Maehara, Satoru Ito, Hiroshi Kawamoto, Satoshi Ozaki, Hisashi Ohta

المصدر: Journal of Pharmacological Sciences, Vol 110, Iss 3, Pp 315-325 (2009)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319311806; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/6bf604453a04428db2000bdf467daf44

المؤلفون: Tomomi Kinoshita, Hiroyuki Ogasawara, Chie Suzuki, Gentaroh Suzuki, Kumiko Ayukawa, Masahiro Furuno

المصدر: SLAS Discovery. 25:287-298

مصطلحات موضوعية: endocrine system, Drug Inverse Agonism, Repressor, GPR3, Endogeny, Biosensing Techniques, Computational biology, Ligands, 01 natural sciences, Biochemistry, Receptors, G-Protein-Coupled, Analytical Chemistry, 03 medical and health sciences, Alzheimer Disease, Cyclic AMP, Humans, Inverse agonist, Receptor, 030304 developmental biology, G protein-coupled receptor, 0303 health sciences, Chemistry, HEK 293 cells, High-Throughput Screening Assays, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cell culture, Molecular Medicine, Protein Binding, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f11df05f1c09a6ec84852b6331e329
https://doi.org/10.1177/2472555219875101

المؤلفون: Ayukawa, Kumiko, Suzuki, Chie, Ogasawara, Hiroyuki, Kinoshita, Tomomi, Furuno, Masahiro, Gentaroh Suzuki

مصطلحات موضوعية: FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256a1476a8a8c1468246988dfaa96593

المؤلفون: Hisashi Ohta, Satoru Ito, Christine Ryan, Gentaroh Suzuki, Jacquelynn J. Cook, Shil Patel, Mangay Williams, Satoshi Ozaki, Stephen Krause, Kerry Riffel, Eric D. Hostetler, Richard Hargreaves, Wai-Si Eng, Stacey O'Malley, Hiroshi Kawamoto, Aniket Joshi, H. Donald Burns, Sandra M. Sanabria-Bohórquez

المصدر: Synapse. 65:125-135

مصطلحات موضوعية: Cerebellum, Allosteric regulation, Antagonist, Human brain, Biology, In vitro, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Metabotropic glutamate receptor, Biophysics, medicine, Metabotropic glutamate receptor 1, Receptor, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c27020ffdfb172d5ff55f79a24c624
https://doi.org/10.1002/syn.20826

المؤلفون: Akio Satow, Shoki Okuda, Miho Nishino, Hiroshi Takehana, Shunsuke Maehara, Hisashi Ohta, Mikiko Hata, Takeshi Murai, Satoko Ise, Gentaroh Suzuki, Hirohiko Hikichi

المصدر: European Journal of Pharmacology. 639:106-114

مصطلحات موضوعية: Central Nervous System, Male, Allosteric modulator, Fever, Pyridones, Central nervous system, Electric Countershock, Rodentia, Pharmacology, Receptors, Metabotropic Glutamate, Inhibitory postsynaptic potential, Rats, Sprague-Dawley, Mice, Cognition, Allosteric Regulation, medicine, Animals, Ultrasonics, Maze Learning, Prepulse inhibition, Mice, Inbred ICR, Behavior, Animal, Chemistry, Metabotropic glutamate receptor 7, Glutamate receptor, Tail suspension test, Rats, Metabotropic receptor, medicine.anatomical_structure, Pentylenetetrazole, Vocalization, Animal, Excitatory Amino Acid Antagonists, Locomotion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c9763e05a5b7c5ebb998829e6e3b19
https://doi.org/10.1016/j.ejphar.2009.08.047

المؤلفون: Akio Satow, Hisashi Ohta, Gentaroh Suzuki

المصدر: Neuroscience. 168:787-796

مصطلحات موضوعية: Male, medicine.medical_specialty, Isoindoles, Nucleus accumbens, Receptors, Metabotropic Glutamate, c-Fos, Rats, Sprague-Dawley, Dorsal raphe nucleus, Allosteric Regulation, Internal medicine, medicine, Animals, biology, General Neuroscience, Brain, Triazoles, Rats, Orexin, Ventral tegmental area, Stria terminalis, medicine.anatomical_structure, Endocrinology, nervous system, Metabotropic glutamate receptor, Schizophrenia, biology.protein, Metabotropic glutamate receptor 1, Psychology, Proto-Oncogene Proteins c-fos, Neuroscience, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a2d0ee4a398ee714b3cf9e4b47b6a3
https://doi.org/10.1016/j.neuroscience.2010.04.016

المؤلفون: Mikiko Hata, Hirohiko Hikichi, Atsushi Satoh, Akio Satow, Toshifumi Kimura, Gentaroh Suzuki, Yasushi Nagatomi, Shunsuke Maehara, Hiroshi Kawamoto, Yukari Hirata, Satoru Ito, Hisashi Ohta

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5464-5468

مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Glutamate receptor, Antagonist, Pharmaceutical Science, Receptors, Metabotropic Glutamate, Biochemistry, In vitro, Rats, Mice, Structure-Activity Relationship, Metabotropic receptor, In vivo, Benzamides, Drug Discovery, Animals, Humans, Molecular Medicine, Structure–activity relationship, Metabotropic glutamate receptor 1, Receptor, Molecular Biology, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c059ff09da4348b24419cec5ab71fa4d
https://doi.org/10.1016/j.bmcl.2009.07.097

المؤلفون: Satoshi Ozaki, Junko Fukuda, Toshifumi Kimura, Satoru Ito, Hiroshi Kawamoto, Hisashi Ohta, Yasushi Nagatomi, Gentaroh Suzuki

المصدر: Neuropharmacology. 57:438-445

مصطلحات موضوعية: Stereochemistry, Morpholines, Receptor, Metabotropic Glutamate 5, Molecular Sequence Data, Allosteric regulation, Intracellular Space, Glutamic Acid, CHO Cells, Biology, Receptors, Metabotropic Glutamate, Cellular and Molecular Neuroscience, Cricetulus, Cricetinae, Animals, Humans, Point Mutation, Amino Acid Sequence, Peptide sequence, Pharmacology, chemistry.chemical_classification, Binding Sites, Dose-Response Relationship, Drug, Sequence Homology, Amino Acid, Chinese hamster ovary cell, Gene Transfer Techniques, Recombinant Proteins, Transmembrane protein, Amino acid, Transmembrane domain, Biochemistry, chemistry, Chromones, Metabotropic glutamate receptor, Metabotropic glutamate receptor 1, Calcium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c66df4ca23f4882374ef9483ec7e0f1
https://doi.org/10.1016/j.neuropharm.2009.06.017

المؤلفون: Takao Inoue, Akio Satow, Hiroshi Kawamoto, Mikiko Hata, Satoru Ito, Takashi Murai, Hisashi Ohta, Hiroko Kawagoe-Takaki, Toshifumi Kimura, Hirohiko Hikichi, Satoshi Ozaki, Gentaroh Suzuki, Shunsuke Maehara

المصدر: Journal of Pharmacological Sciences, Vol 110, Iss 3, Pp 315-325 (2009)

مصطلحات موضوعية: Male, Allosteric regulation, Glycine, CHO Cells, In Vitro Techniques, Pharmacology, Biology, Receptors, Metabotropic Glutamate, Mice, Cricetulus, Allosteric Regulation, In vivo, Cricetinae, Radioligand, Animals, Receptor, Mice, Knockout, Mice, Inbred ICR, Behavior, Animal, Metabotropic glutamate receptor 5, lcsh:RM1-950, Brain, Resorcinols, Triazoles, Recombinant Proteins, lcsh:Therapeutics. Pharmacology, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 1, Ex vivo, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db5771127ecab16634ead57a9390379
https://doi.org/10.1254/jphs.09011fp

المؤلفون: Hideki Kurihara, Hisashi Ohta, Aki Kawagishi, Masayuki Nakamura, Morihiro Mitsuya, Gentaroh Suzuki, Naohiro Tsukamoto, Hiroshi Fushiki, Mitsuru Ohkubo

المصدر: Journal of Pharmacology and Experimental Therapeutics. 323:147-156

مصطلحات موضوعية: Agonist, Pyridones, medicine.drug_class, CHO Cells, Pharmacology, Biology, Receptors, Metabotropic Glutamate, Binding, Competitive, chemistry.chemical_compound, Cricetulus, AMN082, Cricetinae, Cyclic AMP, medicine, Animals, Humans, Cloning, Molecular, RNA, Small Interfering, Oxazoles, Dose-Response Relationship, Drug, Molecular Structure, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 7, Recombinant Proteins, Rats, chemistry, Metabotropic glutamate receptor, Competitive antagonist, Molecular Medicine, Metabotropic glutamate receptor 1, Calcium, Metabotropic glutamate receptor 2, Allosteric Site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0ca64032631f3f52fe8e63152786ee
https://doi.org/10.1124/jpet.107.124701

المؤلفون: Gentaroh Suzuki, Takashi Suyemitsu, Yoshiko Haruguchi, Katsutoshi Ishihara, Keisuke Horii, Kyo Yamasu

المصدر: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1574:311-320

مصطلحات موضوعية: DNA, Complementary, Invertebrate Hormones, Transcription, Genetic, Inverted repeat, Molecular Sequence Data, Biophysics, Biology, Biochemistry, Fungal Proteins, Exon, Structural Biology, Gene duplication, Genetics, Animals, Cloning, Molecular, Protein Precursors, Enhancer, Gene, Genomic organization, Regulation of gene expression, Genome, Base Sequence, Gene Transfer Techniques, Intron, Gene Expression Regulation, Developmental, Exons, Introns, DNA-Binding Proteins, Microscopy, Fluorescence, Sea Urchins, Plasmids, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8437c724db19fcdc554298100ef6fa69
https://doi.org/10.1016/s0167-4781(02)00229-4

المؤلفون: Masayuki Nakamura, Mitsuru Ohkubo, Morihiro Mitsuya, Hideki Kurihara, Hisashi Ohta, Gentaroh Suzuki

المصدر: ChemInform. 41

مصطلحات موضوعية: Biochemistry, In vivo, Chemistry, Metabotropic glutamate receptor 7, Allosteric regulation, Chemical modification, General Medicine, Bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8958acfd71bc4f80fa34a17dbbc145cf
https://doi.org/10.1002/chin.201025137

المؤلفون: Eric D, Hostetler, Waisi, Eng, Aniket D, Joshi, Sandra, Sanabria-Bohórquez, Hiroshi, Kawamoto, Satoru, Ito, Stacey, O'Malley, Stephen, Krause, Christine, Ryan, Shil, Patel, Mangay, Williams, Kerry, Riffel, Gentaroh, Suzuki, Satoshi, Ozaki, Hisashi, Ohta, Jacquelynn, Cook, H Donald, Burns, Richard, Hargreaves

المصدر: Synapse (New York, N.Y.). 65(2)

مصطلحات موضوعية: Brain Mapping, Fluorine Radioisotopes, Binding Sites, Indoles, Dose-Response Relationship, Drug, Brain, Triazoles, Ligands, Receptors, Metabotropic Glutamate, Macaca mulatta, Inhibitory Concentration 50, Positron-Emission Tomography, Animals, Autoradiography, Humans, Tissue Distribution, Excitatory Amino Acid Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::bf12923324fe917efebb48e52de2751c
https://pubmed.ncbi.nlm.nih.gov/20524178

المؤلفون: Hiroshi Kawamoto, Gentaroh Suzuki, Hisashi Ohta

المصدر: Journal of biomolecular screening. 15(2)

مصطلحات موضوعية: CHO Cells, Biology, Receptors, Metabotropic Glutamate, Biochemistry, Models, Biological, Sensitivity and Specificity, beta-Lactamases, Analytical Chemistry, Cricetulus, Genes, Reporter, Cricetinae, Animals, Humans, RNA, Messenger, Reporter gene, Metabotropic glutamate receptor 5, Chinese hamster ovary cell, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 6, Reproducibility of Results, Molecular biology, Excitatory Amino Acid Transporter 1, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 1, Biological Assay, Female, Metabotropic glutamate receptor 2, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535d96adbdf8a2be706ca0313629171c
https://pubmed.ncbi.nlm.nih.gov/20086213

المؤلفون: Hisashi Ohta, Gentaroh Suzuki, Hiroshi Kawamoto

المصدر: Glutamate-based Therapies for Psychiatric Disorders ISBN: 9783034602402

مصطلحات موضوعية: Agonist, animal structures, medicine.drug_class, business.industry, food and beverages, Atypical antipsychotic, Pharmacology, Typical antipsychotic, Dizocilpine, medicine, Haloperidol, Metabotropic glutamate receptor 2, business, health care economics and organizations, Clozapine, Prepulse inhibition, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4d50c1ec9559a519bc7098f2562cafc6
https://doi.org/10.1007/978-3-0346-0241-9_7

المؤلفون: Mitsuru Ohkubo, Gentaroh Suzuki, Morihiro Mitsuya, Hideki Kurihara, Hisashi Ohta, Masayuki Nakamura

المصدر: Bioorganicmedicinal chemistry letters. 20(2)

مصطلحات موضوعية: Pyridones, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Administration, Oral, Receptors, Metabotropic Glutamate, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Structure-Activity Relationship, Allosteric Regulation, In vivo, Drug Discovery, Animals, Molecular Biology, Chemistry, Organic Chemistry, Metabotropic glutamate receptor 7, Glutamate receptor, Chemical modification, Brain, Isoxazoles, Rats, Metabotropic receptor, Lipophilicity, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2276bb6f15e8391d3245f682e20784cb
https://pubmed.ncbi.nlm.nih.gov/20005101

المؤلفون: Satoru Ito, Hisashi Ohta, Takashi Murai, Hiroshi Kawamoto, Mikiko Hata, Shunsuke Maehara, Satoshi Ozaki, Gentaroh Suzuki, Takeshi Murai, Akio Satow, Hiroko Kawagoe-Takaki, Hirohiko Hikichi

المصدر: The Journal of pharmacology and experimental therapeutics. 330(1)

مصطلحات موضوعية: Male, medicine.drug_class, medicine.medical_treatment, Atypical antipsychotic, CHO Cells, Pharmacology, Isoindoles, Motor Activity, Receptors, Metabotropic Glutamate, Rats, Sprague-Dawley, Mice, Cricetulus, Allosteric Regulation, Cricetinae, medicine, Haloperidol, Animals, Humans, Antipsychotic, Clozapine, Metabotropic glutamate receptor 5, Chemistry, Antagonist, Triazoles, Rats, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 1, Excitatory Amino Acid Antagonists, medicine.drug, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4199876254108d5143f6fd89da46d255
https://pubmed.ncbi.nlm.nih.gov/19359526

المؤلفون: Yukari Hirata, Shunsuke Maehara, Akio Satow, Satoru Ito, Hirohiko Hikichi, Hisashi Ohta, Atsushi Satoh, Mikiko Hata, Yasushi Nagatomi, Toshifumi Kimura, Gentaroh Suzuki, Hiroshi Kawamoto

المصدر: Bioorganicmedicinal chemistry letters. 19(18)

مصطلحات موضوعية: Indoles, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Receptors, Metabotropic Glutamate, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, In vivo, Biological profile, Drug Discovery, Animals, Humans, Molecular Biology, Chemistry, Organic Chemistry, Glutamate receptor, Antagonist, In vitro, Rats, Metabotropic receptor, Psychotic Disorders, Hepatocytes, Molecular Medicine, Metabotropic glutamate receptor 1, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9877ee5e442d29384f83497f892539da
https://pubmed.ncbi.nlm.nih.gov/19692242

المؤلفون: Hiroshi Kawamoto, Hirohiko Hikichi, Satoru Ito, Hisashi Ohta, Gentaroh Suzuki, Atsushi Satoh, Toshifumi Kimura, Yukari Hirata, Yasushi Nagatomi, Mikiko Hata, Shunsuke Maehara, Akio Satow

المصدر: Bioorganicmedicinal chemistry. 16(22)

مصطلحات موضوعية: Stereochemistry, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, CHO Cells, Receptors, Metabotropic Glutamate, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Cricetulus, In vivo, Cricetinae, Drug Discovery, Animals, Humans, Molecular Biology, Chemistry, Organic Chemistry, Antagonist, Chemical modification, Biological activity, Rats, Metabotropic receptor, Microsomes, Liver, Molecular Medicine, Metabotropic glutamate receptor 1, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb2586b6cb14c4b8d2ced568820845e
https://pubmed.ncbi.nlm.nih.gov/18849168

المؤلفون: Akio Satow, Satoko Ise, Toshifumi Kimura, Hirohiko Hikichi, Miyuki Fukushima, Gentaroh Suzuki, Takeshi Tanaka, Hiroshi Kawamoto, Satoru Ito, Hisashi Ohta, Shunsuke Maehara

المصدر: The Journal of pharmacology and experimental therapeutics. 326(2)

مصطلحات موضوعية: Male, Reflex, Startle, Fever, Receptor, Metabotropic Glutamate 5, Pain, Pharmacology, Motor Activity, Receptors, Metabotropic Glutamate, Rats, Sprague-Dawley, Mice, Allosteric Regulation, Animals, Maze Learning, Behavior, Animal, Chemistry, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 7, Metabotropic glutamate receptor 6, Brain, Triazoles, Rats, Mice, Inbred C57BL, Anti-Anxiety Agents, Metabotropic glutamate receptor, Competitive antagonist, Molecular Medicine, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2, Vocalization, Animal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ae035e5f52ed3d1a93dc024ae681a7
https://pubmed.ncbi.nlm.nih.gov/18487514