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1
المؤلفون: Genevieve H.L. Roberts, Johannes Rudolph, Karolin Luger
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Indazoles, Indoles, Veliparib, DNA damage, Science, Poly (ADP-Ribose) Polymerase-1, General Physics and Astronomy, Antineoplastic Agents, General Biochemistry, Genetics and Molecular Biology, Article, Catalysis, Piperazines, Olaparib, Target validation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, PARP1, Piperidines, Transferases, Catalytic Domain, Nucleosome, Humans, Binding site, Polymerase, Multidisciplinary, Binding Sites, biology, Chemistry, Nuclear Proteins, General Chemistry, 030104 developmental biology, Histone, DNA Repair Enzymes, 030220 oncology & carcinogenesis, Enzyme mechanisms, Benzamides, biology.protein, Cancer research, Phthalazines, Benzimidazoles, Carrier Proteins, Protein Binding
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2
المصدر: Hum Mol Genet
مصطلحات موضوعية: Male, Multifactorial Inheritance, Genotype, Vitiligo, Genome-wide association study, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Autoimmune Diseases, 03 medical and health sciences, Deep Learning, 0302 clinical medicine, Gene Frequency, Risk Factors, Missing heritability problem, Genetics, medicine, Humans, Family, Genetic Predisposition to Disease, 1000 Genomes Project, Association Studies Article, skin and connective tissue diseases, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, integumentary system, General Medicine, Heritability, medicine.disease, Minor allele frequency, Haplotypes, 030220 oncology & carcinogenesis, Female, Imputation (genetics), Genome-Wide Association Study
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3
المصدر: Pigment Cell Melanoma Res
مصطلحات موضوعية: 0301 basic medicine, Multifactorial Inheritance, Vitiligo, Dermatology, Biology, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, Autoimmunity, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Genetic linkage, medicine, Humans, Genetic Predisposition to Disease, Age of Onset, skin and connective tissue diseases, Genetic association, Autoimmune disease, integumentary system, Haplotype, medicine.disease, Genetic architecture, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Immunology, Age of onset, Genome-Wide Association Study
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4
المؤلفون: Stephanie A. Santorico, Subrata Paul, Richard A. Spritz, Daniel Yorgov, Genevieve H.L. Roberts
المصدر: The American Journal of Human Genetics. 105:364-372
مصطلحات موضوعية: Male, 0301 basic medicine, Multifactorial Inheritance, Genotype, Vitiligo, Genome-wide association study, Disease, Quantitative trait locus, Biology, Polymorphism, Single Nucleotide, Article, Autoimmune Diseases, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Genetics, medicine, Humans, Family, Genetic Predisposition to Disease, Family history, skin and connective tissue diseases, Alleles, Genetics (clinical), Genetic association, Framingham Risk Score, integumentary system, medicine.disease, Genetic architecture, 030104 developmental biology, Genes, Case-Control Studies, Female, 030217 neurology & neurosurgery, Genome-Wide Association Study
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5
المصدر: eLife
eLife, Vol 10 (2021)مصطلحات موضوعية: QH301-705.5, Hydrolases, DNA repair, DNA damage, Science, Poly (ADP-Ribose) Polymerase-1, PARP1, General Biochemistry, Genetics and Molecular Biology, Poly ADP Ribosylation, Biochemistry and Chemical Biology, Hydrolase, Humans, Nucleosome, Biology (General), Polymerase, General Immunology and Microbiology, biology, Chemistry, General Neuroscience, nucleosome, Nuclear Proteins, General Medicine, Nucleosomes, Cell biology, Histone, biology.protein, Medicine, NAD+ kinase, Carrier Proteins, Research Article, Human
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6
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7
المؤلفون: Marie V. Coignet, Eurie L. Hong, Sarah South, Miao Zhang, Harendra Guturu, Pei Jingwen, Jialiang Gu, Brooke Rhead, Michael Gaddis, Cecily Vaughn, Luong Ruiz, Nathan Berkowitz, Cat Foo, Ashley Elrick, Christine Maldonado, Ahna R. Girshick, Heather H. Harris, Ke Bi, Marjan Champine, Evan McCartney-Melstad, Spencer C. Knight, Keith Noto, Barry Starr, Milos Pavlovic, David A. Turrisini, Robert Burton, Kristin A. Rand, Ross E. Curtis, Shea King, Andrey Smelter, Karen Delgado, Yambazi Banda, Asher K. Haug Baltzell, Alisa Sedghifar, Raghavendran Partha, Yong Wang, Abby Drokhlyansky, Genevieve H.L. Roberts, Chodon Sass, Jenna Petersen, Patty Miller, Danny S. Park, Catherine A. Ball, Shannon R. McCurdy
مصطلحات موضوعية: education.field_of_study, Coronavirus disease 2019 (COVID-19), business.industry, Population, Genome-wide association study, Bioinformatics, Phenotype, Intensive care unit, law.invention, law, ABO blood group system, Medicine, business, education, Genetic association, Subclinical infection
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8
مصطلحات موضوعية: Serine, Histone, PARP1, biology, DNA damage, Chemistry, Hydrolase, biology.protein, Nucleosome, NAD+ kinase, Polymerase, Cell biology
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9
المؤلفون: Marie V. Coignet, Dylan Sun, Lukas Habegger, Evan Maxwell, Daniel J. Rader, David J. Carey, Katherine A. Siminovitch, Giorgio Sirugo, Anne E. Justice, Joelle Mbatchou, Eli A. Stahl, Gonçalo R. Abecasis, Alexander H. Li, David A. Turissini, Adam E. Locke, Kristin A. Rand, Aris Baras, Joseph B. Leader, Genevieve H.L. Roberts, Ahna R. Girshick, Deepika Sharma, Nilanjana Banerjee, Fabricio S. P. Kury, John D. Overton, Shane McCarthy, Jonathan Marchini, Xiaodong Bai, Eurie L. Hong, Rouel Lanche, Amy Damask, Ashish Yadav, Raghavendran Partha, Shannon R. McCurdy, Miao Zhang, Suganthi Balasubramanian, Hyun Min Kang, Anurag Verma, Marcus B. Jones, Marylyn D. Ritchie, Colm O'Dushlaine, Manuel A. R. Ferreira, Adam J. Mansfield, Anthony Marcketta, Joshua D. Backman, Alan R. Shuldiner, Michael N. Cantor, Tooraj Mirshahi, Lee Dobbyn, Spencer C. Knight, William J Salerno, Harenda Guturu, Jeffrey G. Reid, Julie E. Horowitz, Lauren Gurski, Danny S. Park, Kyoko Watanabe, Catherine A. Ball, Asher K. Haug Baltzell, Jack A. Kosmicki
مصطلحات موضوعية: 2019-20 coronavirus outbreak, Increased risk, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Genetic variants, MEDLINE, Severe disease, Medicine, Bioinformatics, business
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10
المؤلفون: Catherine A. Ball, Genevieve H.L. Roberts, Shannon R. McCurdy, Eurie L. Hong, Karen Delgado, Danny S. Park, Brooke Rhead, Harendra Guturu, Milos Pavlovic, Asher K. Haug Baltzell, Marie V. Coignet, Miao Zhang, David A. Turissini, Kristin A. Rand, Ahna R. Girshick, Nathan Berkowitz, Spencer C. Knight
مصطلحات موضوعية: medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), business.industry, Public health, Environmental health, Epidemiology, Pandemic, Critical illness, medicine, Area under the curve, business, Odds
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11
المؤلفون: Harendra Guturu, Shannon R. McCurdy, Genevieve H.L. Roberts, Ahna R. Girshick, Asher K. Haug Baltzell, Brooke Rhead, Raghavendran Partha, Marie V. Coignet, Miao Zhang, Spencer C. Knight, Catherine A. Ball, Nathan Berkowitz, Kristin A. Rand, Danny S. Park, Eurie L. Hong
مصطلحات موضوعية: Genetics, Coronavirus disease 2019 (COVID-19), Host (biology), ABO blood group system, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine, Genome-wide association study, medicine.symptom, Genetic risk, Biology, Asymptomatic, Genetic association
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12
المؤلفون: Nanja van Geel, Tracey M. Ferrara, Brent E. Palmer, Stephanie A. Santorico, Albert Wolkerstorfer, Janet C. Siebert, Ying Jin, Richard A. Spritz, Khaled Ezzedine, Songtao Ben, Genevieve H.L. Roberts, Charles Preston Neff
المساهمون: Dermatology
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 10(1):391. Nature Publishing Groupمصطلحات موضوعية: Male, 0301 basic medicine, General Physics and Astronomy, Genome-wide association study, 02 engineering and technology, Vitiligo, Monocytes, Depigmentation, DQ, Medicine and Health Sciences, HLA-DQ beta-Chains, Child, lcsh:Science, skin and connective tissue diseases, Aged, 80 and over, RISK, Genetics, Multidisciplinary, integumentary system, Middle Aged, 021001 nanoscience & nanotechnology, Up-Regulation, PREVALENCE, 3. Good health, Phenotype, Child, Preschool, DISEASES, Female, medicine.symptom, 0210 nano-technology, Adult, DNA ELEMENTS, Adolescent, Genotype, SUSCEPTIBILITY LOCI, Science, Genes, MHC Class II, Locus (genetics), Human leukocyte antigen, Biology, Major histocompatibility complex, Article, General Biochemistry, Genetics and Molecular Biology, Autoimmune Diseases, Young Adult, 03 medical and health sciences, HLA-DQ Antigens, medicine, Humans, Genetic Predisposition to Disease, RNA, Messenger, GENOME-WIDE ASSOCIATION, Aged, MHC class II, Haplotype, Infant, Newborn, Infant, Dendritic Cells, General Chemistry, medicine.disease, 030104 developmental biology, Gene Expression Regulation, Haplotypes, Genetic Loci, biology.protein, lcsh:Q
وصف الملف: application/pdf
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13
المؤلفون: Annette H. Erbse, Pamela N. Dyer, Genevieve H.L. Roberts, Jyothi Mahadevan, Karolin Luger, Uma M. Muthurajan, Johannes Rudolph, Megan Palacio
المصدر: Mol Cell
مصطلحات موضوعية: Models, Molecular, DNA repair, DNA damage, Poly ADP ribose polymerase, Poly (ADP-Ribose) Polymerase-1, Article, Mice, chemistry.chemical_compound, Animals, Humans, Nucleosome, Protein Interaction Domains and Motifs, Molecular Biology, Cells, Cultured, Polymerase, biology, DNA, Cell Biology, Fibroblasts, Nucleosomes, Chromatin, BRCT domain, chemistry, Mutation, Biophysics, biology.protein, Nucleic Acid Conformation, DNA Damage, Protein Binding
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14Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1
المؤلفون: Genevieve H.L. Roberts, Asmita Jha, Karolin Luger, Purushka S. Rae, Uma M. Muthurajan, Guillaume Gaullier, Johannes Rudolph, Jyothi Mahadevan, Samuel Bowerman
المصدر: PLoS ONE, Vol 15, Iss 11, p e0240932 (2020)
PLoS ONEمصطلحات موضوعية: Models, Molecular, Genome instability, Protein Conformation, Gene Expression, Biochemistry, Fluorophotometry, Histones, chemistry.chemical_compound, Spectrum Analysis Techniques, 0302 clinical medicine, Fluorescence Resonance Energy Transfer, DNA Breaks, Double-Stranded, Electron Microscopy, Polymerase, Microscopy, 0303 health sciences, Multidisciplinary, biology, Chromosome Biology, Chemistry, Nucleosome Mapping, Biochemistry and Molecular Biology, Nuclear Proteins, Recombinant Proteins, Chromatin, Nucleosomes, Cell biology, Nucleic acids, Histone, Spectrophotometry, Medicine, Epigenetics, Poly(ADP-ribose) Polymerases, Protein Binding, Research Article, DNA damage, Cellbiologi, Science, Fluorescence Polarization, In Vitro Techniques, Research and Analysis Methods, 03 medical and health sciences, DNA-binding proteins, Genetics, Humans, Point Mutation, Nucleosome, Molecular Biology Techniques, Molecular Biology, 030304 developmental biology, Fluorimetry, Cryoelectron Microscopy, Gene Mapping, Biology and Life Sciences, Proteins, Electron Cryo-Microscopy, DNA, Cell Biology, Linker DNA, Amino Acid Substitution, biology.protein, Mutant Proteins, Carrier Proteins, 030217 neurology & neurosurgery, Biokemi och molekylärbiologi
وصف الملف: application/pdf