يعرض 1 - 20 نتائج من 161 نتيجة بحث عن '"Gelone, Steven P."', وقت الاستعلام: 0.57s تنقيح النتائج
  1. 1
    Academic Journal
    A plain language summary of how lefamulin alone can be used to treat pneumonia caught outside of the hospital due to common bacterial causes, including drug-resistant bacteria

    المؤلفون: Paukner, Susanne, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Vidal, Jorge E, Waites, Ken B, Gelone, Steven P, Yu, Kalvin

    المصدر: Future Microbiology. 17(6)

    مصطلحات موضوعية: Microbiology, Biological Sciences, Emerging Infectious Diseases, Pneumonia & Influenza, Lung, Pneumonia, Antimicrobial Resistance, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Anti-Bacterial Agents, Bacteria, Community-Acquired Infections, Diterpenes, Hospitals, Humans, Language, Pneumonia, Bacterial, Polycyclic Compounds, Thioglycolates, Antibiotic, antibiotic resistance, bacterial pneumonia, infection, lay summary, lefamulin, plain language summary, pleuromutilin, pneumonia, Medical Microbiology

    وصف الملف: application/pdf

    URL الوصول: https://escholarship.org/uc/item/12r90519

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  2. 2
    Academic Journal
    Physiologically‐based pharmacokinetic modeling of the drug–drug interaction between ivacaftor and lefamulin in cystic fibrosis patients

    المؤلفون: Amiel, Magali, Ke, Alice, Gelone, Steven P., Jones, Hannah M., Wicha, Wolfgang

    المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 13, issue 4, page 589-598 ; ISSN 2163-8306 2163-8306

    الاتاحة: http://dx.doi.org/10.1002/psp4.13103
    https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.13103

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  3. 3
    Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

    المؤلفون: Jacobsson, Susanne, 1974, Golparian, Daniel, 1984, Oxelbark, Joakim, 1970, Wicha, Wolfgang W., da Costa, Renata Maria Augusto, Franceschi, Francois, Brown, David, Louie, Arnold, Gelone, Steven P., Drusano, George, Unemo, Magnus, 1970

    المصدر: Frontiers in Pharmacology. 13

    مصطلحات موضوعية: Neisseria gonorrhoeae, antimicrobial treatment, gonorrhea, hollow fiber infection model, lefamulin, pharmacodynamics, pharmacokinetics

    وصف الملف: print

    URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-102537
    https://doi.org/10.3389/fphar.2022.1035841

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  4. 4
    Academic Journal
    Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia : The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial

    المؤلفون: File, Thomas M., Goldberg, Lisa, Das, Anita, Sweeney, Carolyn, Saviski, John, Gelone, Steven P., Seltzer, Elyse, Paukner, Susanne, Wicha, Wolfgang W., Talbot, George H., Gasink, Leanne B.

    المصدر: Clinical Infectious Diseases, 2019 Dec 01. 69(11), 1856-1867.

    URL الوصول: https://www.jstor.org/stable/26856795


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  5. 5
    Academic Journal
    2189. Anti-inflammatory Activity of Lefamulin in a Mouse Model of Influenza Virus H1N1 Infection

    المؤلفون: Wicha, Wolfgang W, Kimber, Sandy, Cumper, Charlotte, Lam, Hon S, Ballesteros, Lorena S, Kirkham, Christopher, Richards, Claire, Gelone, Steven P, Paukner, Susanne

    المصدر: Open Forum Infectious Diseases ; volume 9, issue Supplement_2 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofac492.1808
    https://academic.oup.com/ofid/article-pdf/9/Supplement_2/ofac492.1808/47896539/ofac492.1808.pdf

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  6. 6
    Academic Journal
    1689. In Vitro Activity of Lefamulin Against Bacterial Pathogens Collected From Pneumonia Patients in United States and Latin America Medical Centers in 2020-2021

    المؤلفون: Paukner, Susanne, Ryan Arends, S J, Mendes, Rodrigo E, Gelone, Steven P, Sader, Helio S

    المصدر: Open Forum Infectious Diseases ; volume 9, issue Supplement_2 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofac492.1319
    https://academic.oup.com/ofid/article-pdf/9/Supplement_2/ofac492.1319/47892375/ofac492.1319.pdf

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  7. 7
    Academic Journal
    Pooled microbiological findings and efficacy outcomes by pathogen in adults with community-acquired bacterial pneumonia from the Lefamulin Evaluation Against Pneumonia (LEAP) 1 and LEAP 2 phase 3 trials of lefamulin versus moxifloxacin

    المؤلفون: Paukner, Susanne, Goldberg, Lisa, Alexander, Elizabeth, Das, Anita F., Heinrich, Stefanie, Patel, Pritty, Moran, Gregory J., Sandrock, Christian, File, Thomas M., Vidal, Jorge E., Waites, Ken B., Gelone, Steven P., Schranz, Jennifer

    المصدر: Journal of Global Antimicrobial Resistance ; volume 29, page 434-443 ; ISSN 2213-7165

    الاتاحة: http://dx.doi.org/10.1016/j.jgar.2021.10.021
    https://api.elsevier.com/content/article/PII:S2213716521002459?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S2213716521002459?httpAccept=text/plain

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  8. 8
    Academic Journal
    Tissue Distribution of [ 14 C]-Lefamulin into the Urogenital Tract in Rats

    المؤلفون: Wicha, Wolfgang W., Henson, Claire, Webbley, Kathryn, Gelone, Steven P.

    المساهمون: Nabriva Therapeutics

    المصدر: Antimicrobial Agents and Chemotherapy ; volume 66, issue 8 ; ISSN 0066-4804 1098-6596

    الاتاحة: http://dx.doi.org/10.1128/aac.00355-22
    https://journals.asm.org/doi/pdf/10.1128/aac.00355-22

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  9. 9
    Academic Journal
    Safety and Pharmacokinetics Following Oral or Intravenous Lefamulin in Adults With Cystic Fibrosis

    المؤلفون: Sawicki, Gregory S., Wicha, Wolfgang W., Hiley, Tara S., Close, Nicole C., Gelone, Steven P., Guico-Pabia, Christine J.

    المصدر: Clinical Therapeutics ; volume 46, issue 2, page 96-103 ; ISSN 0149-2918

    الاتاحة: http://dx.doi.org/10.1016/j.clinthera.2023.12.002
    https://api.elsevier.com/content/article/PII:S0149291823004757?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0149291823004757?httpAccept=text/plain

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  10. 10
    Academic Journal
    Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model

    المؤلفون: Hafner, Michael, Paukner, Susanne, Wicha, Wolfgang W., Hrvačić, Boška, Cedilak, Matea, Faraho, Ivan, Gelone, Steven P.

    المساهمون: Mukhopadhyay, Partha, Nabriva Therapeutics

    المصدر: PLOS ONE ; volume 16, issue 9, page e0237659 ; ISSN 1932-6203

    الاتاحة: http://dx.doi.org/10.1371/journal.pone.0237659
    https://dx.plos.org/10.1371/journal.pone.0237659

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  11. 11
    Academic Journal
    A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States

    المؤلفون: Gupta, Vikas, Yu, Kalvin C, Schranz, Jennifer, Gelone, Steven P

    المصدر: Open Forum Infectious Diseases ; volume 8, issue 7 ; ISSN 2328-8957

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofab063
    http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofab063/36196427/ofab063.pdf
    http://academic.oup.com/ofid/article-pdf/8/7/ofab063/40141263/ofab063.pdf

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  12. 12
    Academic Journal
    1320. In Vitro Activity of Lefamulin against Staphylococcus aureus Isolated from the Lower Respiratory Tract of Children with Cystic Fibrosis

    المؤلفون: Sader, Helio S, Paukner, Susanne, Gelone, Steven P, Arends, S J Ryan, Mendes, Rodrigo E

    المصدر: Open Forum Infectious Diseases ; volume 8, issue Supplement_1, page S748-S749 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofab466.1512
    https://academic.oup.com/ofid/article-pdf/8/Supplement_1/S748/41521519/ofab466.1512.pdf

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  13. 13
    Academic Journal
    In Vivo Immune-Modulatory Activity of Lefamulin in an Influenza Virus A (H1N1) Infection Model in Mice.

    المؤلفون: Paukner, Susanne, Kimber, Sandra, Cumper, Charlotte, Rea-Davies, Tina, Sueiro Ballesteros, Lorena, Kirkham, Christopher, Hargreaves, Adam, Gelone, Steven P., Richards, Claire, Wicha, Wolfgang W.

    المصدر: International Journal of Molecular Sciences; May2024, Vol. 25 Issue 10, p5401, 21p

    مصطلحات موضوعية: NEUTROPHILS, ADULT respiratory distress syndrome, INFLUENZA viruses, KILLER cells, COMMUNITY-acquired pneumonia, ANTI-inflammatory agents

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  14. 14
    Academic Journal
    7-Year (2015–21) longitudinal surveillance of lefamulin in vitro activity against bacterial pathogens collected worldwide from patients with respiratory tract infections including pneumonia and characterization of resistance mechanisms.

    المؤلفون: Paukner, Susanne, Mendes, Rodrigo E, Arends, S J Ryan, Gassner, Gisela, Gelone, Steven P, Sader, Helio S

    المصدر: Journal of Antimicrobial Chemotherapy (JAC); Feb2024, Vol. 79 Issue 2, p360-369, 10p

    مصطلحات موضوعية: STREPTOCOCCUS pneumoniae, RESPIRATORY infections, PNEUMONIA, MORAXELLA catarrhalis, PATHOGENIC microorganisms, HAEMOPHILUS influenzae, SUMATRIPTAN


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  15. 15
    Academic Journal
    Pharmacokinetic/pharmacodynamic target attainment analyses to support intravenous and oral lefamulin dose selection for the treatment of patients with community-acquired bacterial pneumonia

    المؤلفون: Bhavnani, Sujata M, Zhang, Li, Hammel, Jeffrey P, Rubino, Christopher M, Bader, Justin C, Sader, Helio S, Gelone, Steven P, Wicha, Wolfgang W, Ambrose, Paul G

    المساهمون: Nabriva Therapeutics, LLC, CHC Group company

    المصدر: Journal of Antimicrobial Chemotherapy ; volume 74, issue Supplement_3, page iii35-iii41 ; ISSN 0305-7453 1460-2091

    الاتاحة: https://doi.org/10.1093/jac/dkz089
    http://academic.oup.com/jac/article-pdf/74/Supplement_3/iii35/28275641/dkz089.pdf

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  16. 16
    Academic Journal
    663. Efficacy and Safety of Lefamulin (LEF) vs. Moxifloxacin (MOX) for Legionella pneumophila (LP) in Patients with Community-Acquired Bacterial Pneumonia (CABP): Pooled Results From the Lefamulin Evaluation Against Pneumonia (LEAP) 1 and LEAP 2 Phase 3 Clinical Trials

    المؤلفون: Shorr, Andrew F, Schranz, Jennifer, Goldberg, Lisa, Paukner, Susanne, Das, Anita F, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Alexander, Elizabeth, Gelone, Steven P

    المصدر: Open Forum Infectious Diseases ; volume 6, issue Supplement_2, page S303-S304 ; ISSN 2328-8957

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofz360.731
    http://academic.oup.com/ofid/article-pdf/6/Supplement_2/S303/30276327/ofz360.731.pdf

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  17. 17
    Academic Journal
    Pharmacokinetics and tolerability of lefamulin following intravenous and oral dosing

    المؤلفون: Wicha, Wolfgang W, Prince, William T, Lell, Claudia, Heilmayer, Werner, Gelone, Steven P

    المساهمون: Nabriva Therapeutics, C4 MedSolutions LLC, CHC Group company

    المصدر: Journal of Antimicrobial Chemotherapy ; volume 74, issue Supplement_3, page iii19-iii26 ; ISSN 0305-7453 1460-2091

    مصطلحات موضوعية: Infectious Diseases, Pharmacology (medical), Pharmacology, Microbiology (medical)

    الاتاحة: http://dx.doi.org/10.1093/jac/dkz087
    http://academic.oup.com/jac/article-pdf/74/Supplement_3/iii19/28275636/dkz087.pdf

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  18. 18
    Academic Journal
    720. Efficacy of Fosfomycin for Injection (FOS) vs. Piperacillin–Tazobactam (PIP-TAZ) in Adults with Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP): ZEUS Study Outcomes in Patients With Reduced Study Drug Susceptibility

    المؤلفون: Kaye, Keith S, Das, Anita F, Eckburg, Paul B, Gelone, Steven P, Schranz, Jennifer, Ellis-Grosse, Evelyn J

    المصدر: Open Forum Infectious Diseases ; volume 6, issue Supplement_2, page S324-S324 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofz360.788
    http://academic.oup.com/ofid/article-pdf/6/Supplement_2/S324/30276835/ofz360.788.pdf

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  19. 19
    Academic Journal
    2233. Efficacy and Symptom Resolution by Visit in Adults With Community-Acquired Bacterial Pneumonia (CABP) Treated With Lefamulin (LEF) or Moxifloxacin (MOX): Pooled Analysis of Lefamulin Evaluation Against Pneumonia (LEAP) 1 and LEAP 2 Study Results

    المؤلفون: Schranz, Jennifer, Das, Anita F, Alexander, Elizabeth, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Gelone, Steven P

    المصدر: Open Forum Infectious Diseases ; volume 6, issue Supplement_2, page S762-S763 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofz360.1911
    http://academic.oup.com/ofid/article-pdf/6/Supplement_2/S762/30273711/ofz360.1911.pdf

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  20. 20
    Academic Journal
    1440. Prevalence and Regional Variation of in ESBLs and CRE Enterobacteriaceae (ENT) among Adult, Hospitalized Patients with ENT on a Urine Culture: A Multicenter Evaluation

    المؤلفون: Lodise, Thomas, Gupta, Vikas, Yu, Kalvin, Gupta, Kalpana, Early, Maureen, Ye, Gang, Schranz, Jennifer, Gelone, Steven P

    المصدر: Open Forum Infectious Diseases ; volume 6, issue Supplement_2, page S525-S526 ; ISSN 2328-8957

    مصطلحات موضوعية: Infectious Diseases, Oncology

    الاتاحة: http://dx.doi.org/10.1093/ofid/ofz360.1304
    http://academic.oup.com/ofid/article-pdf/6/Supplement_2/S525/30276313/ofz360.1304.pdf

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