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1Academic Journal
المؤلفون: Jennifer L. Taylor-Cousar, Marcus A. Mall, Bonnie W. Ramsey, Edward F. McKone, Elizabeth Tullis, Gautham Marigowda, Charlotte M. McKee, David Waltz, Samuel M. Moskowitz, Jessica Savage, Fengjuan Xuan, Steven M. Rowe
المصدر: ERJ Open Research, Vol 5, Iss 2 (2019)
مصطلحات موضوعية: Medicine
وصف الملف: electronic resource
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المؤلفون: JAMES F. MARKMANN, ALI NAJI, MICHAEL R. RICKELS, MARIA ALBA, GAUTHAM MARIGOWDA, LEORAH ROSS, CHENKUN WANG, FELICIA PAGLIUCA, BASTIANO SANNA, LESLIE S. KEAN, ANNE L. PETERS, PIOTR WITKOWSKI, CAMILLO RICORDI
المصدر: Diabetes. 71
مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Internal Medicine
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المؤلفون: Harry G M Heijerman, Edward F McKone, Damian G Downey, Eva Van Braeckel, Steven M Rowe, Elizabeth Tullis, Marcus A Mall, John J Welter, Bonnie W Ramsey, Charlotte M McKee, Gautham Marigowda, Samuel M Moskowitz, David Waltz, Patrick R Sosnay, Christopher Simard, Neil Ahluwalia, Fengjuan Xuan, Yaohua Zhang, Jennifer L Taylor-Cousar, Karen S McCoy, Karen McCoy, Scott Donaldson, Seth Walker, James Chmiel, Ronald Rubenstein, Deborah K. Froh, Isabel Neuringer, Manu Jain, Kathryn Moffett, Jennifer L. Taylor-Cousar, Bruce Barnett, Gary Mueller, Patrick Flume, Floyd Livingston, Nighat Mehdi, Charlotte Teneback, John Welter, Raksha Jain, Dana Kissner, Kapilkumar Patel, Francisco J. Calimano, Jimmy Johannes, Cori Daines, Thomas Keens, Herschel Scher, Subramanyam Chittivelu, Sudhakar Reddivalam, Ross Carl Klingsberg, Larry G. Johnson, Stijn Verhulst, Patricia Macedo, Damien Downey, Gary Connett, Edward Nash, Nicholas Withers, Timothy Lee, Marleen Bakker, Harry Heijerman, Francois Vermeulen, Christiane Knoop, Elke De Wachter, Renske van der Meer, Petrus Merkus, Christof Majoor
المساهمون: Pulmonology, AII - Inflammatory diseases, Clinical sciences, Physiotherapy, Human Physiology and Anatomy, Pediatrics
المصدر: Lancet, 394(10212), 1940-1948. Elsevier Limited
VX17-445-103 Trial Group 2019, ' Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial ', Lancet, vol. 394, no. 10212, pp. 1940 . https://doi.org/10.1016/S0140-6736(19)32597-8
Lancet
The Lancet, 394(10212), 1940. Elsevier Limitedمصطلحات موضوعية: Male, Indoles, Pyrrolidines, Cystic Fibrosis, Pyridines, Clinical Trial, Phase III, Phases of clinical research, Cystic Fibrosis Transmembrane Conductance Regulator, 030204 cardiovascular system & hematology, Quinolones, Aminophenols, Cystic fibrosis, law.invention, Ivacaftor, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, 030212 general & internal medicine, Pyridines/administration & dosage, Non-U.S. Gov't, Chloride Channel Agonists, Sweat, Child, Chloride Channel Agonists/administration & dosage, Medicine(all), biology, Research Support, Non-U.S. Gov't, Lumacaftor, General Medicine, Indoles/administration & dosage, Clinical Trial, Cystic fibrosis transmembrane conductance regulator, Pyrrolidines/administration & dosage, Quinolones/administration & dosage, Randomized Controlled Trial, Combination, Drug Therapy, Combination, Female, medicine.drug, medicine.medical_specialty, Adolescent, Research Support, Article, Benzodioxoles/administration & dosage, Sweat/chemistry, N.I.H, 03 medical and health sciences, Phase III, Research Support, N.I.H., Extramural, Double-Blind Method, Drug Therapy, Internal medicine, Journal Article, medicine, Aminophenols/administration & dosage, Humans, Benzodioxoles, business.industry, Extramural, medicine.disease, Pyrazoles/administration & dosage, Clinical trial, Regimen, chemistry, biology.protein, Pyrazoles, Cystic Fibrosis Transmembrane Conductance Regulator/genetics, sense organs, Cystic Fibrosis/drug therapy, business
وصف الملف: application/pdf; text/plain
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المؤلفون: Mark Kosinski, Alexandra L. Quittner, Ellison Suthoff, Gautham Marigowda, Patrick A. Flume
المصدر: Journal of Cystic Fibrosis. 18:737-742
مصطلحات موضوعية: Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Time Factors, Adolescent, Cystic Fibrosis, Aminopyridines, Quinolones, Aminophenols, Placebo, Vitality, Cystic fibrosis, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Internal medicine, medicine, Humans, In patient, Benzodioxoles, Health related quality of life, business.industry, Recovery of Function, medicine.disease, Clinical trial, Drug Combinations, Treatment Outcome, 030104 developmental biology, 030228 respiratory system, Pediatrics, Perinatology and Child Health, Disease Progression, Quality of Life, Female, Patient-reported outcome, business
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المؤلفون: Fang Liu, David Waltz, Susanna A. McColley, Caroline A. Owen, Chonghua Li, S. Tian, David Stiles, Linda T Wang, Gregory S. Sawicki, John McNamara, Gautham Marigowda
المصدر: The Lancet Respiratory Medicine. 7:325-335
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Cystic Fibrosis, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Phases of clinical research, Quinolones, Aminophenols, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Humans, Medicine, Immunoreactive trypsinogen, Benzodioxoles, 030212 general & internal medicine, Chloride Channel Agonists, Adverse effect, medicine.diagnostic_test, business.industry, Homozygote, Lumacaftor, Age Factors, medicine.disease, 030228 respiratory system, Tolerability, chemistry, Child, Preschool, Pharmacodynamics, Drug Therapy, Combination, Female, business, medicine.drug
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المؤلفون: John G. Jiang, Susanna A. McColley, Michael P. Boyle, Jaime L. Rubin, Bonnie W. Ramsey, Michael W. Konstan, Gautham Marigowda, Montserrat Vera-Llonch, David Waltz, J. Stuart Elborn, Claire E. Wainwright
المصدر: Journal of Cystic Fibrosis. 18:94-101
مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Post hoc, Placebo, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, In patient, Lung function, biology, business.industry, Lumacaftor, medicine.disease, Cystic fibrosis transmembrane conductance regulator, 030104 developmental biology, 030228 respiratory system, chemistry, Pediatrics, Perinatology and Child Health, Cardiology, biology.protein, sense organs, business, medicine.drug
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المؤلفون: Joseph M. Pilewski, Rui Tang, Gautham Marigowda, Jennifer L. Taylor-Cousar, Jeffrey J. Atkinson, Tara Lynn Barto, Tarik Haddad, David Waltz, S. Tian, Manu Jain
المصدر: Journal of Cystic Fibrosis. 17:228-235
مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, Cystic Fibrosis, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, Rate ratio, Cystic fibrosis, Gastroenterology, Ivacaftor, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Forced Expiratory Volume, Internal medicine, medicine, Humans, Benzodioxoles, Prospective Studies, 030212 general & internal medicine, Respiratory system, Adverse effect, business.industry, Homozygote, Lumacaftor, Middle Aged, medicine.disease, Confidence interval, Surgery, Drug Combinations, Treatment Outcome, 030228 respiratory system, Tolerability, chemistry, Pediatrics, Perinatology and Child Health, Female, business, medicine.drug
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المؤلفون: David Waltz, Felix Ratjen, Gautham Marigowda, Margaret Rosenfeld, Carlos Milla, Fang Liu
المصدر: American Journal of Respiratory and Critical Care Medicine. 195:912-920
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Spirometry, medicine.medical_specialty, Cystic Fibrosis, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, Critical Care and Intensive Care Medicine, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Forced Expiratory Volume, Internal medicine, medicine, Humans, Benzodioxoles, 030212 general & internal medicine, Child, Intensive care medicine, Adverse effect, Sweat test, medicine.diagnostic_test, business.industry, Lumacaftor, medicine.disease, Rash, Treatment Outcome, 030228 respiratory system, chemistry, Tolerability, Drug Therapy, Combination, Female, medicine.symptom, business, medicine.drug
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المؤلفون: David Waltz, Gautham Marigowda, Fang Liu
المصدر: Journal of Cystic Fibrosis. 16:246-249
مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, Spirometry, Combination therapy, Respiratory System, Aminopyridines, Quinolones, Aminophenols, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Forced Expiratory Volume, medicine, Humans, Pediatrics, Perinatology, and Child Health, Benzodioxoles, 030212 general & internal medicine, Chloride Channel Agonists, medicine.diagnostic_test, business.industry, Lumacaftor, medicine.disease, Healthy Volunteers, Bronchodilator Agents, 030228 respiratory system, chemistry, Anesthesia, Concomitant, Pediatrics, Perinatology and Child Health, Cohort, Drug Therapy, Combination, Female, sense organs, business, medicine.drug
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المؤلفون: J. Stuart Elborn, David Waltz, Gautham Marigowda, Claire E. Wainwright, Xiaohong Huang, Bonnie W. Ramsey, Michael W. Konstan, Michael P. Boyle
المصدر: The Lancet Respiratory Medicine. 4:617-626
مصطلحات موضوعية: Male, 0301 basic medicine, Cystic Fibrosis, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, Cystic fibrosis, Pulmonary function testing, Ivacaftor, chemistry.chemical_compound, 0302 clinical medicine, Forced Expiratory Volume, Medicine, Child, Chloride Channel Agonists, Lung, Randomized Controlled Trials as Topic, media_common, Homozygote, Lumacaftor, Middle Aged, Respiratory Function Tests, Treatment Outcome, Drug Therapy, Combination, Female, medicine.drug, Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, Placebo, Young Adult, 03 medical and health sciences, Double-Blind Method, Internal medicine, Humans, media_common.cataloged_instance, Benzodioxoles, European union, Adverse effect, business.industry, medicine.disease, Surgery, Clinical trial, 030104 developmental biology, Clinical Trials, Phase III as Topic, 030228 respiratory system, chemistry, business
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المؤلفون: Yvette LeFlore, Srinivas B. Narayan, Dana G. Kissner, Cecile Le Camus, Gautham Marigowda, Christopher Simard
المصدر: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17(6)
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, Cystic Fibrosis, medicine.medical_treatment, Aminopyridines, 030204 cardiovascular system & hematology, Pharmacology, Quinolones, Aminophenols, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, False Positive Reactions, 030212 general & internal medicine, Benzodioxoles, Diagnostic Errors, Chloride Channel Agonists, biology, business.industry, Cannabinoids, Lumacaftor, Middle Aged, medicine.disease, Cystic fibrosis transmembrane conductance regulator, Substance Abuse Detection, Drug Combinations, chemistry, Pediatrics, Perinatology and Child Health, biology.protein, Female, Cannabinoid, business, medicine.drug
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المؤلفون: Susanna A, McColley, Michael W, Konstan, Bonnie W, Ramsey, J, Stuart Elborn, Michael P, Boyle, Claire E, Wainwright, David, Waltz, Montserrat, Vera-Llonch, Gautham, Marigowda, John G, Jiang, Jaime L, Rubin
المصدر: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 18(1)
مصطلحات موضوعية: Adult, Male, Adolescent, Cystic Fibrosis, Aminopyridines, Middle Aged, Quinolones, Aminophenols, Article, Respiratory Function Tests, Drug Combinations, Young Adult, Treatment Outcome, Double-Blind Method, Forced Expiratory Volume, Disease Progression, Humans, Female, sense organs, Benzodioxoles, Child, Lung, Aged, Follow-Up Studies, Retrospective Studies
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المؤلفون: Gautham Marigowda, Susanna A. McColley, David Waltz, Fang Liu, Linda T Wang, John McNamara, S. Tian, Caroline A. Owen, David Stiles, Chonghua Li, Gregory S. Sawicki
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Lumacaftor, Phases of clinical research, Clinical trial, Ivacaftor, chemistry.chemical_compound, chemistry, Tolerability, Internal medicine, Pharmacodynamics, Medicine, Data monitoring committee, Immunoreactive trypsinogen, business, medicine.drug
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المؤلفون: Alan S. Brody, Gautham Marigowda, Jonathan G. Goldin, Felix Ratjen, Linda T Wang, David Waltz, C Hug, Scott K. Nagle
المصدر: Cystic fibrosis: disease trajectory and evolving therapies.
مصطلحات موضوعية: Bronchiectasis, Lung, business.industry, Lumacaftor, 030204 cardiovascular system & hematology, medicine.disease, Placebo, Air trapping, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine.anatomical_structure, 030228 respiratory system, chemistry, medicine, Lung volumes, medicine.symptom, business, Nuclear medicine, medicine.drug
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المؤلفون: M. Bsharat, Jordana E. Hoppe, Mark A. Chilvers, Melinda Solomon, C Hug, Gregory S. Sawicki, Gautham Marigowda, Margaret Rosenfeld, Philip Black, S. Tian
المصدر: Cystic fibrosis: disease trajectory and evolving therapies.
مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, business.industry, Lumacaftor, Lung Clearance Index, medicine.disease, Cystic fibrosis, Gastroenterology, Ivacaftor, chemistry.chemical_compound, chemistry, Internal medicine, Clinical endpoint, Medicine, Lung volumes, business, Adverse effect, Body mass index, medicine.drug
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المؤلفون: Scott K. Nagle, Linda T Wang, KM Johnson, Gautham Marigowda, Alan S. Brody, Jonathan G. Goldin, Felix Ratjen, C Hug, Jason C. Woods, David Waltz
المصدر: Clinical implications of cystic fibrosis.
مصطلحات موضوعية: medicine.medical_specialty, Bronchiectasis, medicine.diagnostic_test, business.industry, Lumacaftor, Magnetic resonance imaging, medicine.disease, Placebo, Cystic fibrosis, Ivacaftor, chemistry.chemical_compound, chemistry, Multicenter trial, medicine, Ultrashort echo time, Radiology, business, medicine.drug
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المؤلفون: Laura A. Sass, Thomas Lahiri, Alicia Casey, Carlos Milla, James F. Chmiel, Fadi Asfour, Seth Walker, Alastair Reid, Jane C. Davies, Michael J. Rock, Xiaohong Huang, Barry Clements, Ronald C. Rubenstein, Tacjana Pressler, Philippe Reix, Anne Munck, Howard Schmidt, Timothy D. Starner, Doris Staab, Stephanie Bui, Christiane De Boeck, Melinda Solomon, Don S. Urquhart, Diana Quintero, Tim Lee, Gautham Marigowda, Fadel Ruiz, Margaret Rosenfeld, Floyd Livingston, Sanja Stanojevic, Matthias Griese, Anne Malfroot, Deborah Froh, Mark A. Chilvers, Isabelle Sermet Gaudelus, John McNamara, Sibylle Junge, Thomas G. Keens, Aaron Chidekel, Ian M. Balfour-Lynn, S. Tian, Claire E. Wainwright, Brian O'Sullivan, Susanna A. McColley, Christopher Hug, Philip Black, Lutz Naehrlich, Silke van Koningsburggen-Rietschel, Philip Robinson, John L. Colombo, Hiranjan Selvadurai, Felix Ratjen, George Z. Retsch-Bogart, Carlos E Milla, David M. Orenstein, David Schaeffer, Lena Hjelte, David Waltz, Alexandra G Cornell, Jodi Hilton, Larry C. Lands, Paul Robinson, Patrick A. Flume, Gary Mueller
المساهمون: Clinical sciences, Growth and Development
المصدر: The Lancet. Respiratory medicine. 5(7)
مصطلحات موضوعية: Male, Pediatrics, Cystic Fibrosis, Respiratory System, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, Cystic fibrosis, DISEASE, law.invention, Ivacaftor, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Forced Expiratory Volume, Surveys and Questionnaires, Clinical endpoint, 030212 general & internal medicine, Child, Chloride Channel Agonists, Sweat, Lung, ABNORMALITIES, Lumacaftor, INERT-GAS WASHOUT, Drug Combinations, Mucociliary Clearance, Female, Life Sciences & Biomedicine, CLINICAL-TRIALS, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, YOUNG-CHILDREN, Placebo, LUNG CLEARANCE INDEX, 1117 Public Health and Health Services, 03 medical and health sciences, Critical Care Medicine, Double-Blind Method, General & Internal Medicine, medicine, Humans, Benzodioxoles, Adverse effect, Science & Technology, business.industry, 1103 Clinical Sciences, IN-VITRO, medicine.disease, PHE508DEL CFTR, CFTR POTENTIATOR, Clinical trial, 030228 respiratory system, chemistry, Mutation, VX14-809-109 investigator group, business, 1199 Other Medical and Health Sciences
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المؤلفون: S. Tian, John McNamara, David Waltz, Gregory S. Sawicki, Gautham Marigowda, Susanna A. McColley, Caroline A. Owen, Fang Liu
المصدر: Journal of Cystic Fibrosis. 17:S2-S3
مصطلحات موضوعية: 030203 arthritis & rheumatology, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Combination therapy, business.industry, Lumacaftor, medicine.disease, Cystic fibrosis, Gastroenterology, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, chemistry, Internal medicine, Pediatrics, Perinatology and Child Health, Mutation (genetic algorithm), medicine, F508del cftr, In patient, business, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Shamsah Kazani, Matteo Bonini, Michael E. Wechsler, Emiko Ono, Elliot Israel, Gautham Marigowda, Anna Planaguma, Bruce D. Levy, Muhammad Zahid
المصدر: Journal of allergy and clinical immunology 132 (2013): 547–553. doi:10.1016/j.jaci.2013.01.058
info:cnr-pdr/source/autori:Kazani S.; Planaguma A.; Ono E.; Bonini M.; Zahid M.; Marigowda G.; Wechsler M.E.; Levy B.D.; Israel E./titolo:Exhaled breath condensate eicosanoid levels associate with asthma and its severity/doi:10.1016%2Fj.jaci.2013.01.058/rivista:Journal of allergy and clinical immunology/anno:2013/pagina_da:547/pagina_a:553/intervallo_pagine:547–553/volume:132مصطلحات موضوعية: Adult, Male, genetic structures, Adolescent, Leukotriene B4, Immunology, [object Object], Severity of Illness Index, eicosanoids, Article, Young Adult, chemistry.chemical_compound, medicine, Humans, Immunology and Allergy, Exhaled breath condensate, Asthma, Leukotriene, Lipoxin, medicine.diagnostic_test, business.industry, Area under the curve, biomarkers, Middle Aged, medicine.disease, respiratory tract diseases, Lipoxins, Bronchoalveolar lavage, Breath Tests, Eicosanoid, chemistry, Exhalation, Female, business
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المؤلفون: Scott C. Bell, Susanna A. McColley, Michael P. Boyle, Michael W. Konstan, Gautham Marigowda, Steven M. Rowe, Ernst Rietschel, David Waltz, Xiaolei Li
مصطلحات موضوعية: 0301 basic medicine, Male, Cystic Fibrosis, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, Gastroenterology, Cystic fibrosis, Body Mass Index, Ivacaftor, chemistry.chemical_compound, 0302 clinical medicine, Forced Expiratory Volume, F508del cftr, Sweat, Original Research, Lumacaftor, respiratory system, Middle Aged, Europe, medicine.anatomical_structure, Treatment Outcome, Cohort, Female, medicine.drug, Pulmonary and Respiratory Medicine, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Placebo, 03 medical and health sciences, Young Adult, Chlorides, Double-Blind Method, Internal medicine, medicine, Humans, Benzodioxoles, Adverse effect, Lung, Dose-Response Relationship, Drug, business.industry, Australia, medicine.disease, United States, Surgery, respiratory tract diseases, 030104 developmental biology, 030228 respiratory system, chemistry, Mutation, business
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