المؤلفون: Atla, Goutlam, Bonàs-Guarch, S., Cuenca-Ardura, M., Beucher, A., Crouch, D. J. M., Garcia-Hurtado, J., Moran, I., Irimia, M., Prasad, R. B., Gloyn, A. L., Marselli, L., Suleiman, M., Berney, T., De Koning, E. J. P., Pattou KERR-CONTE, Julie, Pattou, Francois, Todd, J. A., Piemonti, L., Ferrer, J.

المساهمون: Université de Lille, Inserm, CHU Lille, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Recherche translationnelle sur le diabète (RTD) - U1190

مصطلحات موضوعية: RNA splicing, Type 1 diabetes, Type 2 diabetes, TWAS, G-protein signaling, Pancreatic islets, Beta cells, Senescence, CTRB2, Pancreatic beta-cells, Diabetes pathophysiology, Quantitative trait loci

وصف الملف: application/octet-stream; application/rdf+xml; charset=utf-8; application/pdf

Relation: Genome Biology; Genome Biol; http://hdl.handle.net/20.500.12210/103337

الاتاحة: https://hdl.handle.net/20.500.12210/103337

المؤلفون: Zabal Aguirre, Mario, Arroyo, F., García-Hurtado, J., De la Torre, J., Hewitt, G.M., Bella, J.L.

المساهمون: UAM. Departamento de Biología

مصطلحات موضوعية: Chorthippus, Cytoplasmic incompatibility, Hybrid zones, Wolbachia, Biología y Biomedicina / Biología

وصف الملف: application/pdf

Relation: Journal of Evolutionary Biology; https://doi.org/10.1111/jeb.12389; http://hdl.handle.net/10486/710390; 1136; 1148; 27

الاتاحة: http://hdl.handle.net/10486/710390
https://doi.org/10.1111/jeb.12389

المؤلفون: Atla, G, Bonas-Guarch, S, Cuenca-Ardura, M, Beucher, A, Crouch, DJM, Garcia-Hurtado, J, Moran, I, The T2DSystems Consortium, Irimia, M, Prasad, RB, Gloyn, AL, Marselli, L, Suleiman, M, Berney, T, De Koning, EJP, Kerr-Conte, J, Pattou, F, Todd, JA, Piemonti, L, Ferrer, J

المساهمون: Wellcome Trust, Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC)

المصدر: 28 ; 1

مصطلحات موضوعية: Beta cells, CTRB2, Diabetes pathophysiology, G-protein signaling, Pancreatic beta-cells, Pancreatic islets, Quantitative trait loci, RNA splicing, Senescence, TWAS, Type 1 diabetes, Type 2 diabetes, Diabetes Mellitus, Type 1, Type 2, Exodeoxyribonucleases, Humans, Islets of Langerhans, Proinsulin, Protein Isoforms, RNA, Long Noncoding, T2DSystems Consortium, 05 Environmental Sciences, 06 Biological Sciences, 08 Information and Computing Sciences, Bioinformatics

Relation: Genome Biology; http://hdl.handle.net/10044/1/99574; 101033/C/13/Z; RDC03 79560; MR/L02036X/1; RDC03

الاتاحة: http://hdl.handle.net/10044/1/99574
https://doi.org/10.1186/s13059-022-02757-0

المؤلفون: Miguel-Escalada, I, Maestro, MÁ, Balboa, D, Elek, A, Bernal, A, Bernardo, E, Grau, V, García-Hurtado, J, Sebé-Pedrós, A, Ferrer, J

المساهمون: Wellcome Trust, Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC)

المصدر: 1936.e9 ; 1922

مصطلحات موضوعية: Mendelian disease, NEUROG3, PTF1A, diabetes mellitus, endocrine differentiation, enhancers, non-coding mutations, pancreas development, stem cell differentiation, Pancreas, Animals, Humans, Mice, Transcription Factors, Cell Differentiation, Gene Expression Regulation, Developmental, Regulatory Sequences, Nucleic Acid, Mutation, Infant, Newborn, Enhancer Elements, Genetic, Developmental Biology, 06 Biological Sciences, 11 Medical and Health Sciences

جغرافية الموضوع: United States

Relation: Developmental Cell; http://hdl.handle.net/10044/1/99332; 101033/C/13/Z; RDC03 79560; MR/L02036X/1; RDB03 79560; RDF03; RDC03

الاتاحة: http://hdl.handle.net/10044/1/99332
https://doi.org/10.1016/j.devcel.2022.07.014

المؤلفون: Rovira, M., Atla, G., Maestro, M. A., Grau, V., García-Hurtado, J., Maqueda, M., Mosquera, J. L., Yamada, Y., Kerr-Conte, Julie, Pattou, Francois, Ferrer, J.

المساهمون: Universitat de Barcelona (UB), Institut d'Investigació Biomèdica de Bellvitge = Bellvitge Biomedical Research Institute (IDIBELL), Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Instituto de Salud Carlos III Madrid (ISCIII)-ministerio de ciencia e innovacion, Barcelona Institute of Science and Technology (BIST), Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III Madrid (ISCIII), The University of Tokyo (UTokyo), Recherche translationnelle sur le diabète - U 1190 (RTD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Institut Européen de Génomique du Diabète - European Genomic Institute for Diabetes - FR 3508 (EGID), Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Imperial College London, This research was supported by Ministerio de Ciencia, Innovación y Universidades (SAF2015-73226-JIN Agencia Estatal de Investigación {AEI}/European Regional Development Fund, European Union {UE} and RYC-2017-21950 AEI/European Social Fund, UE to M.R., and BFU2014-54284-R and RTI2018-095666-B-I00 to J.F.), the Medical Research Council (MR/L02036X/1), Wellcome Trust (WT101033), and European Research Council Advanced Grant (789055) (to J.F.), the Instituto de Salud Carlos III (CA18/00045 to J.L.M.), and a Spanish Ministry of Science, Innovation, andUniversities (MCIU) fellowship (PTA2018-016371-I to M.M.). J.K.-C.’s and F.P.’s research was supported by L’Agence Nationale de la Recherche (ANR) grants, L’Institut Européen de Génomique du Diabète (EGID), ANR-10-LABX-0046, a French state fund managed by ANR under the frame program Investissements d’Avenir (I-SITE ULNE/ANR-16-IDEX-0004 ULNE to F.P.), and the European Consortium for Islet Transplantation funded bythe Juvenile Diabetes Research Foundation International. Work in the Centre for Genomic Regulation was supported by the Centres de Recerca de Catalunya (CERCA) Programme, Generalitat de Catalunya, and Centro de Excelencia Severo Ochoa (SEV-2015-0510). Work at Institut d’Investigació Biomèdica de Bellvitge was supported by the CERCA Programme and Generalitat de Catalunya., ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), ANR-16-IDEX-0004,ULNE,ULNE(2016), European Project: 789055,10.3030/789055,DecodeDiabetes(2018)

المصدر: ISSN: 0890-9369 ; Genes and Development ; https://hal.univ-lille.fr/hal-04719007 ; Genes and Development, 2021, Genes and Development, 35 (17-18), p. 1229-1242. ⟨10.1101/gad.348501.121⟩.

مصطلحات موضوعية: REST, beta cells, bipotent progenitors, endocrine differentiation, pancreas, pancreas development, transcriptional repressors, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/34385258; info:eu-repo/grantAgreement//789055/EU/Expanding the genetic etiological and diagnostic spectrum of monogenic diabetes mellitus/DecodeDiabetes; PUBMED: 34385258; PUBMEDCENTRAL: PMC8415321

الاتاحة: https://hal.univ-lille.fr/hal-04719007
https://hal.univ-lille.fr/hal-04719007v1/document
https://hal.univ-lille.fr/hal-04719007v1/file/Genes%20Dev.-2021-Rovira-1229-42.pdf
https://doi.org/10.1101/gad.348501.121

المؤلفون: Akerman, I, Maestro, MA, De Franco, E, Grau, V, Flanagan, S, García-Hurtado, J, Mittler, G, Ravassard, P, Piemonti, L, Ellard, S, Hattersley, AT, Ferrer, J

مصطلحات موضوعية: INS promoter, regulatory element, mouse model, neonatal diabetes, GLIS3

Relation: Vol. 35 (2), article 108981; 20/0006136; SBF006\1140; BFU2014-54284-R; RTI2018-095666-B-I00; MR/L02036X/1; WT101033; 789055; 518153; 19/005971; WT098395/Z/12/Z; 105636/Z/14/Z; http://hdl.handle.net/10871/125654; Cell Reports

الاتاحة: http://hdl.handle.net/10871/125654
https://doi.org/10.1016/j.celrep.2021.108981

المؤلفون: Akerman, I., Maestro, M., Franco, E., Grau, V., Flanagan, S., García-Hurtado, J., Mittler, G., Ravassard, P., Piemonti, L., Ellard, S., Hattersley, A., Ferrer, J.

المصدر: Cell Reports

وصف الملف: application/pdf

Relation: http://hdl.handle.net/21.11116/0000-0008-5149-B; http://hdl.handle.net/21.11116/0000-0008-514B-9

الاتاحة: http://hdl.handle.net/21.11116/0000-0008-5149-B
http://hdl.handle.net/21.11116/0000-0008-514B-9

المؤلفون: Van Arensbergen, J, Dussaud, S, Pardanaud-Glavieux, C, Garcia-Hurtado, J, Sauty, C, Guerci, A, Ferrer, J, Ravassard, P

المساهمون: Medical Research Council (MRC)

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, GENE-EXPRESSION, PROGENITOR CELLS, BETA-CELLS, GROUP PROTEINS, HISTONE H2A, NEUROGENIN3, CHROMATIN, MICE, UBIQUITINATION, RECRUITMENT, General Science & Technology, MD Multidisciplinary

Relation: PLOS ONE; http://hdl.handle.net/10044/1/45776; https://dx.doi.org/10.1371/journal.pone.0171508; MR/L02036X/1

الاتاحة: http://hdl.handle.net/10044/1/45776
https://doi.org/10.1371/journal.pone.0171508

المؤلفون: Akerman, I, Tu, Z, Beucher, A, Rolando, DM, Sauty-Colace, C, Benazra, M, Nakic, N, Yang, J, Wang, H, Pasquali, L, Moran, I, Garcia-Hurtado, J, Castro, N, Gonzalez-Franco, R, Stewart, AF, Bonner, C, Piemonti, L, Berney, T, Groop, L, Kerr-Conte, J, Pattou, F, Argmann, C, Schadt, E, Ravassard, P, Ferrer, J

المساهمون: Wellcome Trust, Medical Research Council (MRC), National Institutes of Health, Imperial College Healthcare NHS Trust- BRC Funding

المصدر: 411 ; 400

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, Endocrinology & Metabolism, LONG NONCODING RNAS, GENE-EXPRESSION, TRANSCRIPTIONAL LANDSCAPE, ENDOCRINE PANCREAS, REVEALS, DIFFERENTIATION, EVOLUTION, LINCRNAS, PDX-1, LINE, CRISPR interference, PDX1, PLUTO, chromatin, diabetes, lncRNAs, pancreatic islets, transcriptional networks, type 2 diabetes, Diabetes Mellitus, Type 2, Gene Expression Regulation, Gene Knockdown Techniques, Gene Regulatory Networks, Homeodomain Proteins, Humans

جغرافية الموضوع: United States

Relation: Cell Metabolism; http://hdl.handle.net/10044/1/43718; 101033/C/13/Z; MR/L02036X/1; UFDSP00010725; RDC03 79560

الاتاحة: http://hdl.handle.net/10044/1/43718
https://doi.org/10.1016/j.cmet.2016.11.016

المؤلفون: Rodríguez Marín, J., Pastor Mira, M. A., López Roig, S., García-Hurtado, J., Sánchez Pérez, S.

المصدر: Análisis y Modificación de Conducta; Vol. 15 Núm. 43 (1989) ; 2173-6855 ; 0211-7339 ; 10.33776/amc.v15i43

Relation: http://www.uhu.es/publicaciones/ojs/index.php/amc/article/view/1870

الاتاحة: http://www.uhu.es/publicaciones/ojs/index.php/amc/article/view/1870
https://doi.org/10.33776/amc.v15i43.1870

المؤلفون: Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O., Grarup, N., Ravassard, P., Torrents, D., Mercader, J. M., Piemonti, L., Berney, T., De Koning, E. J. P., Pattou KERR-CONTE, Julie, Pattou, Francois, Fedko, I. O., Groop, L., Prokopenko, I., Hansen, T., Marti-Renom, M. A., Fraser, P., Ferrer, J.

المساهمون: Université de Lille, Inserm, CHU Lille, Recherche translationnelle sur le diabète (RTD) - U1190

Relation: Nat. Genet.; http://hdl.handle.net/20.500.12210/103450

الاتاحة: https://hdl.handle.net/20.500.12210/103450

المؤلفون: Garcia Hurtado, J. (Juan)

وصف الملف: application/pdf

الاتاحة: http://jultika.oulu.fi/Record/nbnfioulu-201906062479

المؤلفون: Morán, I, Akerman, I, van de Bunt, M, Xie, R, Benazra, M, Nammo, T, Arnes, L, Nakić, N, García-Hurtado, J, Rodríguez-Seguí, S, Pasquali, L, Sauty-Colace, C, Beucher, A, Scharfmann, R, van Arensbergen, J, Johnson, P, Berry, A, Lee, C, Harkins, T, Gmyr, V, Pattou, F, Kerr-Conte, J, Piemonti, L, Berney, T, Hanley, N

Relation: https://ora.ox.ac.uk/objects/uuid:94eddb3c-3e8c-4377-b096-f3e0dc034833; https://doi.org/10.1016/j.cmet.2012.08.010

الاتاحة: https://doi.org/10.1016/j.cmet.2012.08.010
https://ora.ox.ac.uk/objects/uuid:94eddb3c-3e8c-4377-b096-f3e0dc034833

المؤلفون: Pasquali, L, Gaulton, K, Rodríguez-Seguí, SA, Mularoni, L, Miguel-Escalada, I, Akerman, I, Tena, J, Morán, I, Gómez-Marín, C, Van De Bunt, M, Ponsa-Cobas, J, Castro, N, Nammo, T, Cebola, I, García-Hurtado, J, Maestro, M, Pattou, F, Piemonti, L, Berney, T, Gloyn, A, Ravassard, P, Skarmeta, J, Müller, F, Mccarthy, M, Ferrer, J

Relation: https://ora.ox.ac.uk/objects/uuid:7cf7a35c-f077-44ea-8d11-ec7825883696; https://doi.org/10.1038/ng.2870

الاتاحة: https://doi.org/10.1038/ng.2870
https://ora.ox.ac.uk/objects/uuid:7cf7a35c-f077-44ea-8d11-ec7825883696

المؤلفون: Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García Hurtado J, Rodríguez Seguí S, Pasquali P, Sauty Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins, T, Gmyr v, Pattou F, Kerr Conte J, Berney T, Hanley L, Gloyn A, Sussel L, Langman L, Braymnan KL, Sander M, McCarthy M, Ravassard P, Ferrer J., PIEMONTI , LORENZO

المساهمون: Morán, I, Akerman, I, van de Bunt, M, Xie, R, Benazra, M, Nammo, T, Arnes, L, Nakić, N, García Hurtado, J, Rodríguez Seguí, S, Pasquali, P, Sauty Colace, C, Beucher, A, Scharfmann, R, van Arensbergen, J, Johnson, Pr, Berry, A, Lee, C, Harkins, T, Gmyr, V, Pattou, F, Kerr Conte, J, Piemonti, Lorenzo, Berney, T, Hanley, L, Gloyn, A, Sussel, L, Langman, L, Braymnan, Kl, Sander, M, Mccarthy, M, Ravassard, P, Ferrer, J.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_____10495::da1eca1c65db7be445eada760bd91b30

المؤلفون: Allen, H.L., Flanagan, S.E., Shaw-Smith, C., Franco, E. De, Akerman, I., Caswell, R., Ferrer, J., Hattersley, A.T., Ellard, S., Aanstoot, H.J., Aberg, E., Adolfsson, P., Anthony, M., Batlle, M., Bruining, J, Bühr, P., Cummings, E., Edge, J., Garcia-Hurtado, J., Hathout, E., Ho, J., Jeffries, C., Temple, I.K., Kaufman, E., Kotori, V.M., Krijger, R. de, Kummer, M., Mackay, D., Mace, J., Noordam, C., O'Brien, F., Rubio-Cabezas, O., Shield, J., Skidmore, D., White, S., Zanier, U.

المصدر: Nature Genetics, 44, 1, pp. 20-2

مصطلحات موضوعية: IGMD 8: Mitochondrial medicine

Relation: http://hdl.handle.net/2066/97931; https://doi.org/10.1038/ng.1035

الاتاحة: http://hdl.handle.net/2066/97931
https://doi.org/10.1038/ng.1035

المؤلفون: Guzmán, OF1.,, Vargas, García, Marín Maya, E., García Hurtado, J.

المصدر: Congreso Internacional de Investigacion Academia Journals; 2016, Vol. 8 Issue 1, p1505-1510, 6p

المؤلفون: Pasquali, L., Gaulton, K.J., Rodríguez-Seguí, S.A., Mularoni, L., Miguel-Escalada, I., Akerman, I., Tena, J.J., Morán, I., Gómez-Marín, C., Van De Bunt, M., Ponsa-Cobas, J., Castro, N., Nammo, T., Cebola, I., García-Hurtado, J., Maestro, M.A., Pattou, F., Piemonti, L., Berney, T., Gloyn, A.L., Ravassard, P., Skarmeta, J.L.G., Müller, F., Mccarthy, M.I., Ferrer, J.

مصطلحات موضوعية: glucose, transcription factor, article, chromatin, controlled study, DNA binding, enhancer region, epigenetics, gene cluster, gene control, gene disruption, gene sequence, genetic association, genetic risk, genetic variability, glucose blood level, human, non insulin dependent diabetes mellitus, nonhuman, pancreas insufficiency, pancreas islet, pathogenesis, priority journal, Base Sequence, Chromatin Immunoprecipitation, Diabetes Mellitus, Type 2, Electrophoretic Mobility Shift Assay, Enhancer Elements, Genetic

Relation: http://hdl.handle.net/20.500.12110/paper_10614036_v46_n2_p136_Pasquali

الاتاحة: https://hdl.handle.net/20.500.12110/paper_10614036_v46_n2_p136_Pasquali

المؤلفون: Zabal‐Aguirre, M., Arroyo, F., García‐Hurtado, J., Torre, J., Hewitt, G. M., Bella, J. L.

المصدر: Journal of Evolutionary Biology; Jun2014, Vol. 27 Issue 6, p1136-1148, 13p

مصطلحات موضوعية: WOLBACHIA, POPULATION biology, CHORTHIPPUS parallelus, PYRENEAN oak, CYTOPLASM, INSECT reproduction, PHYSIOLOGY

المؤلفون: García Hurtado, J., Bago y Valldecabres, M. R., Jiménez Alegre, M. D.

المساهمون: Universidad de Alicante. ICE

مصطلحات موضوعية: estilo cognitivo, proceso cognitivo, conducta del profesor, relación profesor-alumno, aprendizaje

Relation: http://hdl.handle.net/11162/84570; p. 76-86; EC I/11

الاتاحة: http://hdl.handle.net/11162/84570