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1Academic Journal
المؤلفون: Daniel W. Robbins, Mark A. Noviski, Ying Siow Tan, Zef A. Konst, Aileen Kelly, Paul Auger, Nivetha Brathaban, Robert Cass, Ming Liang Chan, Ganesh Cherala, Matthew C. Clifton, Stefan Gajewski, Timothy G. Ingallinera, Dane Karr, Daisuke Kato, Jun Ma, Jenny McKinnell, Joel McIntosh, Jeff Mihalic, Brent Murphy, Jaipal Reddy Panga, Ge Peng, Janine Powers, Luz Perez, Ryan Rountree, Austin Tenn-McClellan, Arthur T. Sands, Dahlia R. Weiss, Jeffrey Wu, Jordan Ye, Cristiana Guiducci, Gwenn Hansen, Frederick Cohen
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, transcription factors ikzf1, molecular glue interactions, human clinical trials, attractive therapeutic target, preclinical oncology models, many hematological malignancies, degradation across species, concomitant immunomodulatory activity, btk enzymatic function, orally bioavailable degrader, mediated bcr signaling, orally bioavailable, immunomodulatory activity, preclinical pharmacology, btk degrader, vivo <, tyrosine kinase
الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01007.s001
https://figshare.com/articles/journal_contribution/Discovery_and_Preclinical_Pharmacology_of_NX-2127_an_Orally_Bioavailable_Degrader_of_Bruton_s_Tyrosine_Kinase_with_Immunomodulatory_Activity_for_the_Treatment_of_Patients_with_B_Cell_Malignancies/25130114 -
2Academic Journal
المؤلفون: Kim Linton, Francesco Forconi, David Lewis, John Riches, Dima El-Sharkawi, Mary Gleeson, Sarah G Injac, Srinand Nandakumar, May Tan, Ganesh Cherala, Graham P Collins
المصدر: HemaSphere, Vol 7, p e593178d (2023)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Ganesh Cherala, Cara Nelson, Ying Guo, Anubhav Mathur, Thomas Tarnowski, Ahmed A. Othman
المصدر: Clinical and Translational Science, Vol 15, Iss 6, Pp 1492-1499 (2022)
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270
وصف الملف: electronic resource
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4
المؤلفون: Eric Helmer, Negin Karimian, Karen Van Assche, Ineke Seghers, Sandrine Le Tallec, Ganesh Cherala, Graham Scott, Florence S. Namour
المصدر: Clinical Pharmacology & Therapeutics. 112:901-908
مصطلحات موضوعية: Adult, Pharmacology, Cross-Over Studies, Adolescent, Middle Aged, Ethinyl Estradiol, Young Adult, Cytochrome P-450 CYP3A, Humans, Drug Interactions, Female, Pharmacology (medical), Sulfotransferases, Aged, Contraceptives, Oral
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5
المؤلفون: Alison B, Edelman, Jon D, Hennebold, Kise, Bond, Jeong Y, Lim, Ganesh, Cherala, David F, Archer, Jeffrey T, Jensen
المصدر: Obstetrics & Gynecology. 140:48-54
مصطلحات موضوعية: Adult, Ovulation, Humans, Obstetrics and Gynecology, Female, Levonorgestrel, Obesity, Contraception, Postcoital, Progesterone
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6
المؤلفون: Sarah Whelan, Christopher Karim, Jordan Ye, Timothy Ingallinera, Ganesh Cherala, Katherine Jameson, Anja Williams, Adam Sharp, Matthew Krebs, Simon Pacey, Sarah Blagden, Ruth Plummer, Daniel Hochhauser, Jeff Evans, Johann De Bono, Janine Powers
المصدر: Regular and Young Investigator Award Abstracts.
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7
المؤلفون: Anees M. Dauki, Chia‐Hsiang Hsueh, Ganesh Cherala, Ahmed A. Othman
المصدر: Clinical pharmacology and therapeutics. 112(3)
مصطلحات موضوعية: Pharmacology, Blood Glucose, Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Insulin, Pharmacology (medical), Drug Interactions, Glucose Tolerance Test, Metformin
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8
المؤلفون: Clare E. Parker, Ari Waisman, Lindsay H. Laws, Yoshinobu Koguchi, Martin H. Oberbarnscheidt, Mark K. Slifka, Leonardo V. Riella, Jagdeep S. Obhrai, Melissa Y. Yeung, Ganesh Cherala
المصدر: American Journal of Transplantation. 16:3139-3149
مصطلحات موضوعية: Graft Rejection, Male, medicine.drug_class, Inflammation, 030230 surgery, Monoclonal antibody, Article, Lymphocyte Depletion, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Immunologic Factors, Immunology and Allergy, Pharmacology (medical), Receptor, B cell, B-Lymphocytes, Mice, Inbred BALB C, Transplantation, biology, business.industry, Graft Survival, Alloimmunity, Immunoglobulins, Intravenous, Antigens, CD20, Mice, Inbred C57BL, medicine.anatomical_structure, Immunology, biology.protein, Heart Transplantation, Female, Rituximab, Antibody, medicine.symptom, business, 030215 immunology, medicine.drug
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9
المصدر: Contraception. 94:104-108
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Contraceptive efficacy, Research methodology, Treatment outcome, MEDLINE, Levonorgestrel, 03 medical and health sciences, Health services, 0302 clinical medicine, Contraceptive Agents, Female, medicine, Humans, Gynecology, 030219 obstetrics & reproductive medicine, Hematologic tests, Obstetrics, business.industry, Obstetrics and Gynecology, Treatment Outcome, 030104 developmental biology, Reproductive Medicine, Family planning, Female, business, medicine.drug
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10
المؤلفون: Charles O'Neill, Mika Aoyagi-Scharber, Jukka Poulivali, Sundeep Chandra, Ashley Frazer-Abel, Maria Hedlund, Nicole A. Datson, Andrew Melton, David Jacoby, M Benjamin Hock, Ganesh Cherala, Sylvia Fong, Todd M. Oppeneer, Judith C.T. van Deutekom, Shripad Bhagwat, Xiefan Fang
المصدر: Neuromuscular Disorders. 30:S169
مصطلحات موضوعية: Presentation, History, Neurology, media_common.quotation_subject, Pediatrics, Perinatology and Child Health, Neurology (clinical), Genetics (clinical), media_common, Visual arts
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11
المصدر: Basic & Clinical Pharmacology & Toxicology. 118:432-439
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Offspring, Intrauterine growth restriction, Weaning, Urine, Organic Anion Transporters, Sodium-Independent, Biology, Diet, High-Fat, Kidney, Toxicology, 03 medical and health sciences, Organic Anion Transport Protein 1, Sex Factors, Sodium Potassium Chloride Symporter Inhibitors, Pharmacokinetics, Furosemide, Pregnancy, Internal medicine, Diet, Protein-Restricted, medicine, Animals, Humans, Solute Carrier Family 12, Member 1, Pharmacology, Volume of distribution, Fetal Growth Retardation, Body Weight, General Medicine, medicine.disease, Rats, 030104 developmental biology, Endocrinology, Prenatal Exposure Delayed Effects, Body Composition, Female, medicine.drug
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12
المؤلفون: Jessica Atrio, Frank Z. Stanczyk, Ganesh Cherala, Barent N. DuBois
المصدر: Contraception. 91:71-75
مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Metabolic Clearance Rate, Pyridines, Atazanavir Sulfate, Population, Radioimmunoassay, Pharmacology, Article, Young Adult, Pharmacokinetics, Internal medicine, HIV Seropositivity, medicine, Humans, Drug Interactions, education, Prospective cohort study, education.field_of_study, Ritonavir, business.industry, Area under the curve, virus diseases, Obstetrics and Gynecology, HIV Protease Inhibitors, Contraceptives, Oral, Synthetic, Up-Regulation, Atazanavir, Regimen, Reproductive Medicine, Drug Therapy, Combination, Female, Norethindrone, Progestins, business, Oligopeptides, Half-Life, medicine.drug
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13
المؤلفون: Jeffrey T. Jensen, Martha McInnis, Alison Edelman, Myrna Y. Munar, Ganesh Cherala, Frank Z. Stanczyk
المصدر: Contraception. 90:550-556
مصطلحات موضوعية: Adult, Population, Levonorgestrel, Pharmacology, Ethinyl Estradiol, Article, law.invention, Young Adult, Pharmacokinetics, Randomized controlled trial, law, Humans, Medicine, Obesity, Prospective Studies, Young adult, education, Prospective cohort study, education.field_of_study, business.industry, Obstetrics and Gynecology, Contraceptives, Oral, Combined, Reproductive Medicine, Hormonal contraception, Female, business, medicine.drug, Hormone
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14
المؤلفون: Ganesh Cherala, Arthur Legg, Rachel E. Sunstrom, Stephen M. Langley, Jennifer H. Huang, Myrna Y. Munar, Ali J. Olyeai
المصدر: The Journal of Thoracic and Cardiovascular Surgery. 148:1591-1596
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Article, law.invention, Predictive Value of Tests, law, Cardiopulmonary bypass, Humans, Medicine, Computer Simulation, Dosing, Cardiac Surgical Procedures, Volume of distribution, Cefuroxime, business.industry, Infant, Perioperative, Nomogram, Anti-Bacterial Agents, Cardiac surgery, Surgery, Child, Preschool, Predictive value of tests, Anesthesia, Cardiology and Cardiovascular Medicine, business, medicine.drug
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15
المؤلفون: Ganesh Cherala, Kent L. Thornburg, Barent N. DuBois, Jacob Pearson, Duc X. Nguyen, Tahir Mahmood
المصدر: European Journal of Pharmacology. 728:39-47
مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.medical_treatment, Diuresis, Renal function, Nephron, Kidney, Article, Natriuresis, Furosemide, Pregnancy, Internal medicine, Diet, Protein-Restricted, medicine, Animals, Lactation, Diuretics, Prenatal Nutritional Physiological Phenomena, Pharmacology, Fetal Growth Retardation, business.industry, Body Weight, Blood Proteins, Rats, Endocrinology, medicine.anatomical_structure, Liver, Prenatal Exposure Delayed Effects, Renal physiology, Female, Diuretic, business, Protein Binding, medicine.drug
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16
المؤلفون: Daniel R. Mishell, Frank Z. Stanczyk, Andrea Kovacs, Jessica Atrio, Michael Neely, Ganesh Cherala
المصدر: Journal of Acquired Immune Deficiency Syndromes (1999)
مصطلحات موضوعية: Adult, medicine.medical_specialty, Population, efficacy, HIV Infections, protease inhibitor, Pharmacokinetics, Hiv infected, medicine, HIV Protease Inhibitor, Humans, Pharmacology (medical), Protease inhibitor (pharmacology), education, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), License, Gynecology, education.field_of_study, business.industry, hormonal contraception, HIV, drug interactions, HIV Protease Inhibitors, Clinical Science, Contraceptives, Oral, Synthetic, 3. Good health, progestin only pills, Infectious Diseases, contraception, Hormonal contraception, Family planning, Family medicine, Female, Norethindrone, business, pharmacokinetics
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17
المؤلفون: Ganesh Cherala, Craig D. Williams, Shobana Ganesan, Cheryl L. Maslen
المصدر: British Journal of Clinical Pharmacology. 75:1468-1477
مصطلحات موضوعية: Pharmacology, Metabolite, Vasodilator-stimulated phosphoprotein, Clopidogrel, Blood proteins, chemistry.chemical_compound, chemistry, Pharmacokinetics, medicine, Platelet aggregation inhibitor, Pharmacology (medical), Ticlopidine, Active metabolite, medicine.drug
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18
المؤلفون: Lisa Bleyle, Amira Al-Uzri, Myrna Y. Munar, Dennis R. Koop, Ganesh Cherala
المصدر: Journal of Chromatography B. 926:54-61
مصطلحات موضوعية: Clinical Biochemistry, Renal function, Biochemistry, High-performance liquid chromatography, Article, Tacrolimus, Analytical Chemistry, chemistry.chemical_compound, Limit of Detection, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, medicine, Humans, Ascomycin, Creatinine, Chromatography, medicine.diagnostic_test, Chemistry, Reproducibility of Results, Cell Biology, General Medicine, Dried blood spot, surgical procedures, operative, Therapeutic drug monitoring, Chromatography, Liquid, Blood drawing, medicine.drug
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19
المؤلفون: Ganesh Cherala, Myrna Y. Munar, Martha McInnis, Alison Edelman, Barent N. DuBois, Jeffrey T. Jensen, Frank Z. Stanczyk
المصدر: Contraception. 87:220-226
مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Population, Levonorgestrel, Ethinyl Estradiol, Article, Body Mass Index, Cohort Studies, Pharmacokinetics, Internal medicine, medicine, Humans, Obesity, Prospective Studies, Prospective cohort study, education, Progesterone, education.field_of_study, Estradiol, business.industry, Area under the curve, Obstetrics and Gynecology, medicine.disease, Contraceptives, Oral, Combined, Drug Combinations, Transvaginal ultrasound, Endocrinology, Reproductive Medicine, Female, business, Body mass index, medicine.drug
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20
المؤلفون: Ganesh Cherala, Jeffrey T. Jensen, Hong Li, Francis K.-Y. Pau, Alison Edelman, Diana L. Blithe
مصطلحات موضوعية: 0301 basic medicine, Adult, Ovulation, medicine.medical_specialty, Time Factors, media_common.quotation_subject, Levonorgestrel butanoate, Population, Pilot Projects, Kaplan-Meier Estimate, Injections, Intramuscular, Article, Body Mass Index, 03 medical and health sciences, Oregon, Young Adult, 0302 clinical medicine, Norgestrel, Contraceptive Agents, Female, Medicine, Humans, Levonorgestrel, Obesity, Prospective Studies, Prospective cohort study, education, media_common, Gynecology, education.field_of_study, 030219 obstetrics & reproductive medicine, business.industry, Body Weight, Obstetrics and Gynecology, 030104 developmental biology, Reproductive Medicine, Female, business, Intramuscular injection, Body mass index, medicine.drug