المؤلفون: Tanweer A. Khan, Pauline C. Ting, Deborra Mullins, Hongwu Wang, Yonglian Zhang, Gallo Gioconda, Manuel de Lera Ruiz, Gang Zhou, Andrew Stamford, Biju J. Purakkattle, Rongze Kuang, Tao Yu, Robert G. Aslanian, He-Ping Wu, Robert A. Hodgson, Dong Xiao

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:1348-1354

مصطلحات موضوعية: Receptor, Adenosine A2A, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Moiety, Binding site, Molecular Biology, Binding Sites, Bicyclic molecule, Organic Chemistry, Adenosine receptor, In vitro, Adenosine A2 Receptor Antagonists, Protein Structure, Tertiary, Rats, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, chemistry, Drug Design, Quinazolines, Molecular Medicine, Lead compound, 030217 neurology & neurosurgery, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf503a1e4d6200fd3aaf41ddea45dc8c
https://doi.org/10.1016/j.bmcl.2015.11.048

المؤلفون: Dmitri A. Pissarnitski, Zhiqiang Zhao, Mary Cohen-Williams, Troy McCraken, Lili Zhang, George Sun, Wei Zhou, Mihirbaran Mandal, Hongmei Li, Xianhai Huang, Duane A. Burnett, Zhaoning Zhu, Xiaoxiang Liu, Inhou Chu, Anandan Palani, Robert G. Aslanian, John W. Clader, Gallo Gioconda, Lynn A. Hyde, Chad Bennett, David Cole, Monica Vicarel, Alexei V. Buevich, Michael Czarniecki, William J. Greenlee, Lixin Song, Xiaohong Zhu

المصدر: ACS Medicinal Chemistry Letters. 3:931-935

مصطلحات موضوعية: biology, business.industry, Organic Chemistry, Cleavage (embryo), Biochemistry, Combinatorial chemistry, Structural framework, In vitro, chemistry.chemical_compound, chemistry, In vivo, Morpholine, Drug Discovery, Amyloid precursor protein, biology.protein, Medicine, γ secretase, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3575eaf01068003a61b49639e08f3779
https://doi.org/10.1021/ml300209g

المؤلفون: Sun, Zhong-Yue, Asberom, Theodros, Bara, Thomas, Bennett, Chad, Burnett, Duane, Chu, Inhou, Clader, John, Cohen-Williams, Mary, Cole, David, Czarniecki, Michael, Durkin, James, Gallo, Gioconda, Greenlee, William, Josien, Hubert, Huang, Xianhai, Hyde, Lynn, Jones, Nicholas, Kazakevich, Irina, Li, Hongmei, Liu, Xiaoxiang, Lee, Julie, MacCoss, Malcolm, Mandal, Mihir B., McCracken, Troy, Nomeir, Amin, Mazzola, Robert, Palani, Anandan, Parker, Eric M., Pissarnitski, Dmitri A., Qin, Jun, Song, Lixin, Terracina, Giuseppe, Vicarel, Monica, Voigt, Johannes, Xu, Ruo, Zhang, Lili, Zhang, Qi, Zhao, Zhiqiang, Zhu, Xiaohong, Zhu, Zhaoning

المصدر: Journal of Medicinal Chemistry ; volume 55, issue 1, page 489-502 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm201407j
https://pubs.acs.org/doi/pdf/10.1021/jm201407j