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المؤلفون: Daniel J. Lisko, Bruce A. Vallance, Kevin Tsai, Laura Cook, Alana Schick, Kevan Jacobson, Genelle R Healey
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1251-1266 (2021)مصطلحات موضوعية: EEN IN, inulin-type fructan enriched exclusive enteral nutrition, medicine.medical_treatment, T-Lymphocytes, Prebiotic, HDAC, histone deacetylase, RC799-869, IN, inulin-type fructan, Inflammatory bowel disease, Regulatory T Cells, Mice, 0302 clinical medicine, RAR-related orphan receptor gamma, Medicine, Original Research, Mice, Knockout, 0303 health sciences, IBD, inflammatory bowel disease, Gastroenterology, FOXP3, Forkhead Transcription Factors, Diseases of the digestive system. Gastroenterology, GI, gastrointestinal, Colitis, 3. Good health, Phenotype, 030220 oncology & carcinogenesis, SCFA, short-chain fatty acid, Tregs, regulatory T cells, Tumor necrosis factor alpha, Disease Susceptibility, IP, intraperitoneal, GPR, G-protein coupled receptor, PBS, phosphate-buffered saline, Butyrate, PPARγ, proliferator-activated receptor gamma, Immunomodulation, 03 medical and health sciences, MLN, mesenteric lymph nodes, Immune system, Enteral Nutrition, CD, Crohn’s disease, Animals, 030304 developmental biology, Hepatology, business.industry, Inflammatory Bowel Disease, EEN, exclusive enteral nutrition, medicine.disease, IL, interleukin, Gastrointestinal Microbiome, PAS, periodic acid-Schiff, UC, ulcerative colitis, Disease Models, Animal, Prebiotics, BCFA, branch-chain fatty acids, Immunology, DAS, disease activity score, Microbiome, business, Biomarkers
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المؤلفون: Chien-wen Su, Catherine Stanton, Bobby J. Cherayil, Shane O’Donnell, Chih-Yu Chen, Tangyou Mao, Shao Rong Long, Lefei Jiao, Hai Ning Shi, Qiaorong Ji, W. Allan Walker, Shasha Zheng
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 763-778 (2020)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, OGTT, oral glucose tolerance test, medicine.medical_treatment, HFD-Hp_mac, macrophages from Heligmosomoides polygyrus–infected, high-fat diet–fed mice, Gut flora, GPR, G protein–coupled receptor, 0302 clinical medicine, fluids and secretions, Cells, Cultured, Original Research, Nematospiroides dubius, biology, Gastroenterology, mRNA, messenger RNA, High-fat diet, HFD-Cont_mac, macrophages from control high-fat diet–fed mice, HFD+Cont-F, mice that received fecal material from control donors, SCFA, short-chain fatty acid, 030211 gastroenterology & hepatology, Diet, High-Fat, LEfSe, linear discriminant analysis of effect size, digestive system, 03 medical and health sciences, Immune system, parasitic diseases, medicine, Helminth, Animals, Microbiome, Obesity, lcsh:RC799-869, Strongylida Infections, PCA, principal component analysis, Hepatology, Immunotherapy, Protective Factors, biology.organism_classification, medicine.disease, WT, wild-type, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, IL, interleukin, Gastrointestinal Microbiome, Mice, Inbred C57BL, Transplantation, 030104 developmental biology, Immunology, Type 2 immunity, HFD+Hp-F, mice that received fecal material from Heligmosomoides polygyrus–infected donors, lcsh:Diseases of the digestive system. Gastroenterology, Heligmosomoides polygyrus, Metabolic syndrome
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المؤلفون: Phillip A. Engen, Stefan J. Green, Brandon B. Shetuni, Khashayarsha Khazaie, Robin M. Voigt, Abu Osman, Bruce R. Hamaker, Ali Keshavarzian, Sherry Wilber, Maliha Shaikh, Abdulrahman Saadalla, Garth Swanson, Ankur Naqib, Faraz Bishehsari, Christopher B. Forsyth
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 219-237 (2020)مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, STAT3, signal transducer and activator of transcription 3, Carcinogenesis, Colorectal cancer, Cell, Food Time, Receptors, G-Protein-Coupled, Mice, 0302 clinical medicine, Intestinal Mucosa, ANOVA, analysis of variance, Original Research, 2. Zero hunger, Colon Cancer, Microbiota, Circadian, Gastroenterology, Period Circadian Proteins, Colitis, GPR, G-protein–coupled receptor, Circadian Rhythm, 3. Good health, PER2, Butyrates, medicine.anatomical_structure, eTreg, extrathymically induced FOXP3+ regulatory T cell, CRC, colorectal cancer, SCFA, short-chain fatty acid, ZT, Zeitgeber time, 030211 gastroenterology & hepatology, medicine.symptom, Alcohol, CCL, Chemokine ligand, Alcohol Drinking, Colon, Regulatory T cell, Photoperiod, Treg, regulatory T cell, Colonic Polyps, Mice, Transgenic, Inflammation, Butyrate, Proinflammatory cytokine, 03 medical and health sciences, ANOSIM, analysis of similarity, CRD, circadian rhythm disruption, medicine, Animals, Humans, lcsh:RC799-869, Immunity, Mucosal, Th, T-helper, Ethanol, Hepatology, business.industry, WTE, wrong-time eating: eating during rest phase, Epithelial Cells, RORγt+, RAR-related orphan receptor γ-positive, Feeding Behavior, medicine.disease, Gastrointestinal Microbiome, Disease Models, Animal, 030104 developmental biology, Cancer research, STAT protein, lcsh:Diseases of the digestive system. Gastroenterology, TS4/APC, TS4Cre × APCΔ468, Colitis-Associated Neoplasms, business, RTE, right-time eating: eating during active phase
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المؤلفون: Moss, Joe W.E., Williams, Jessica O., Ramji, Dipak P.
المصدر: Biochimica et Biophysica Acta
مصطلحات موضوعية: ANCHOR, Effect of AMR101 (Icosapent Ethyl) on Triglyceride Levels in Patients on Statins With High Triglyceride Levels (≥200 and <500 mg/dL), FMD, flow-mediated dilation, TMAO, trimethylamine-N-oxide, VEAPS, Vitamin E Atherosclerosis Prevention Study, CHD, coronary heart disease, MAGMA, Multi-Analyte, Genetic, and Thrombogenic Markers of Atherosclerosis, DGLA, dihomo-gamma-linolenic acid, OPTILIP, The Quantification of the Optimal n-6/n-3 ratio in the UK Diet, LDL, low-density lipoprotein, VLDL, very low-density lipoprotein, EUROLIVE, Effect of Olive Oils on Oxidative Damage in European Populations, ASAP, Antioxidant Supplementation in Atherosclerosis Prevention, LDLR, LDL receptor, FOURIER, Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk, Cardiovascular disease, ECM, extracellular matrix, TG, triacylglycerol, GPR, G-protein-coupled receptor, KIHD, Kuopio Ischaemic Heart Disease Risk Factor, ESRD, end stage renal disease, CoCoA, Cocoa, Cognition and Aging, CRP, C-reactive protein, MI, myocardial infarction, Fatty Acids, Unsaturated, REDUCE-IT, Reduction of Cardiovascular Events with EPA – Intervention Trial, Nutraceuticals, CIRT, Cardiovascular Inflammation Reduction Trial, SU.VI.MAX, Supplementation en Vitamines et Mineraux Antioxydant, HDL, high-density lipoprotein, CVD, cardiovascular disease, ORIGIN, Outcome Reduction with an Initial Glargine Intervention, Article, MRS-ROZE, Multicenter Randomized Study of ROsuvastatin and eZEtimibe, OMEGA, Effect of Omega 3-Fatty Acids on the Reduction of Sudden Cardiac Death After Myocardial Infarction, IMPROVE-IT, Improved Reduction of Outcomes: Vytorin Efficacy International Trial, PUFA, polyunsaturated fatty acid, PREDIMED, Prevención con Dieta Mediterránea, Animals, Humans, cardiovascular diseases, oxLDL, oxidized LDL, PRECISE-IVUS, Plaque Regression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by Intravascular Ultrasound, GISSI, Gruppo Italiano per lo Studio della Sopravvivenza nell'infarlo, Flavonoids, MARINE, Multi-center, plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label Extension, NO, nitric oxide, STRENGTH, STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia, GLA, gamma-linolenic acid, Polyphenols, CANTOS, Canakinumab Anti-inflammatory Thrombosis Outcomes Study, LDL-C, LDL-cholesterol, EPA, eicosapentaenoic acid, Atherosclerosis, CoQ10, coenzyme Q10, JELIS, Japan EPA Lipid Intervention Study, IL, interleukin, Apo, apolipoprotein, Dietary Supplements, Polyunsaturated fatty acids, PCSK9, proprotein convertase subtilisin/kexin type 9, PWV, pulse wave velocity
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المصدر: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 143, Iss, Pp 112095-(2021)مصطلحات موضوعية: AICAR, 5-amino-4-imidazolecarboxamide riboside, DNMTs, DNA methyltransferases, BPA, Bisphenol A, Bioinformatics, Epigenesis, Genetic, Mas R, Mas receptor, SARS-CoV-2, Severe acute respiratory syndrome coronavirus-2, Transcription (biology), RAAS, Renin-angiotensin-aldosterone system, Hypoxia, Regulation of gene expression, biology, HIF, Hypoxia-inducible factor, ER, Estrogen receptors, Drugs, MERS-CoV, Middle East respiratory syndrome coronavirus, PM, Particulate matter, General Medicine, ACEi, ACE inhibitors, CTD, C-terminal domain, HRE, Hypoxia-responsive elements, Histone, S-protein, Spike protein, Angiotensin-converting enzyme 2, DNA methylation, ACEIs, Angiotensin-converting enzyme inhibitors, ARBs, Angiotensin receptor blockers, GPR, G protein-coupled receptor, Angiotensin-Converting Enzyme 2, hormones, hormone substitutes, and hormone antagonists, GRAVY, Grand average of Hydrophobicity, NO2, Nitrogen dioxide, PRR, Prorenin receptor, ACE2, Angiotensin-converting enzyme-2, RM1-950, Hazardous Substances, Article, Environmental toxicants, CQ, Chloroquine phosphate, Viral entry, microRNA, SIRT1, Silent information regulator, Humans, Epigenetics, NTD, N-terminal domain, 8-HDS, Hydroxydihydrosanguinarine, Endocrine disruptors, EGCG, Epigallocatechin-3-gallate, RBM, Receptor-binding motif, Pharmacology, Epidrugs, SARS-CoV-2, HDAC, Histone deacetylase, COVID-19, Virus Internalization, NRF2, Nuclear factor erythroid 2-related factor 2, Gene Expression Regulation, biology.protein, RBD, Receptor-binding domain, Therapeutics. Pharmacology
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المؤلفون: Ahmed M. Darwesh, Wesam Bassiouni, Deanna K Sosnowski, John M. Seubert
المصدر: Pharmacology & Therapeutics
مصطلحات موضوعية: 0301 basic medicine, TX, Thromboxane, nCoVs, Novel coronaviruses, medicine.medical_treatment, Bioinformatics, medicine.disease_cause, 0302 clinical medicine, CVD, Cardiovascular disease, TNF-α, Tumor necrosis factor-α, Medicine, IL, Interleukin, PG, Prostaglandin, Pharmacology (medical), PUFA, Polyunsaturated fatty acid, LPS, Lipopolysaccharide, Randomized Controlled Trials as Topic, chemistry.chemical_classification, COVID-19, Coronavirus disease 2019, EDP, Epoxydocosapentaenoic acid, HDHA, Hydroxydocosahexaenoic acid, CYP, Cytochrome P450, HDL-c, High density lipoprotein cholesterol, ARB, Angiotensin II receptor blocker, Cardiovascular disorders, AA, Arachidonic acid, DHA, Docosahexaenoic acid, Eicosapentaenoic acid, EPA, Eicosapentaenoic acid, n-3 polyunsaturated fatty acids, IFN, Interferon, 3. Good health, MERS-CoV, Middle East respiratory syndrome-related coronavirus, ICU, Intensive care unit, Cardiovascular Diseases, Chemotherapy, Adjuvant, Docosahexaenoic acid, 030220 oncology & carcinogenesis, NLRP3, NOD, LRR and pyrin domains-containing protein 3, ALA, α-Linolenic acid, CRP, C-reactive protein, Cytokine Release Syndrome, Adjuvant, TLR, Toll-like receptor, Polyunsaturated fatty acid, GPR, G-protein coupled receptor, LOX, Lipoxygenase, COX, Cyclooxygenase, HF, Heart failure, Article, PPAR, Peroxisome proliferator-activated receptor, SARS-CoV, Severe acute respiratory syndrome coronavirus, 03 medical and health sciences, Immune system, EEQ, Epoxyeicosatetraenoic acid, SPM, Specialized pro-resolving mediators, Fatty Acids, Omega-3, ARDS, Acute respiratory distress syndrome, RAAS, Renin-angiotensin aldosterone system, Adjuvant therapy, Coagulopathy, Animals, Humans, LT, Leukotriene, RNA, Ribonucleic acid, Inflammation, Pharmacology, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, LA, Linoleic acid, PMN, Polymorphonuclear neutrophils, business.industry, ALI, Acute lung injury, COVID-19, medicine.disease, ACE, Angiotensin converting enzyme, COVID-19 Drug Treatment, Oxidative Stress, 030104 developmental biology, chemistry, NF-κB, Nuclear factor kappa-light-chain-enhancer of activated B cells, MI, Myocardial infarction, Bioactive metabolites, business, Oxidative stress, Ang, Angiotensin, ROS, Reactive oxygen species
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المؤلفون: Gerhard Rogler, Pedro A. Ruiz, Cheryl de Valliere, Jonas Zeitz, Jyrki J. Eloranta, Hassan Melhem, Irina Tcymbarevich, Kirstin Atrott, Benjamin Misselwitz, Gerd A. Kullak-Ublick, Michael Fried, Klaus Seuwen, Carsten A. Wagner, Mehdi Madanchi, Jesus Cosin-Roger, Simona Simmen, Stephan R. Vavricka
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 6, Pp 796-810 (2016)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: WT, wild type, 0301 basic medicine, MM6, MonoMac 6, HV, healthy volunteer, SPARC, secreted protein acidic and rich in cysteine, NF-κB, nuclear factor-κB, Inflammation, Biology, IEC, intestinal epithelial cell, 03 medical and health sciences, Intestinal mucosa, TDAG8, Ovarian Cancer G-Protein–Coupled Receptor, medicine, OGR1, ovarian cancer G-protein–coupled receptor 1 (GPR68), IFN, interferon, lcsh:RC799-869, Receptor, Original Research, Th, T-helper, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, Hepatology, RT-qPCR, quantitative reverse-transcription polymerase chain reaction, AICAR, 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside, TDAG8, T-cell death-associated gene 8 (GPR65), Inflammatory Bowel Disease, GRP65, Gastroenterology, Hypoxia (medical), Molecular biology, GPR, G-protein–coupled receptor, mRNA, messenger RNA, IL, interleukin, ChIP, chromatin immunoprecipitation, HIF, hypoxia-inducible factor, UC, ulcerative colitis, 030104 developmental biology, Hypoxia-inducible factors, Cancer research, CD, Crohn's disease, lcsh:Diseases of the digestive system. Gastroenterology, Tumor necrosis factor alpha, FCS, fetal calf serum, medicine.symptom, Chromatin immunoprecipitation, Homeostasis
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المؤلفون: Emeran A. Mayer, Amir Kalani, Vadim Osadchiy, Clair R. Martin
المصدر: Cellular and molecular gastroenterology and hepatology, vol 6, iss 2
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, GPR, SPF, TGR5, G protein-coupled bile acid receptor, 5-HT, Review, Gut flora, Trp, Irritable Bowel Syndrome, SPF, specific-pathogen-free, 0302 clinical medicine, EEC, enteroendocrine cell, FGF, BGM, 5-HT, serotonin, Irritable bowel syndrome, EEC, brain-gut-microbiome, ECC, enterochromaffin cell, biology, digestive, oral, and skin physiology, lipopolysaccharide, TGR5, Gastroenterology, GLP-1, glucagon-like peptide-1, GI, gastrointestinal, GF, GPR, G-protein–coupled receptor, GI, FFAR, free fatty acid receptor, medicine.anatomical_structure, specific-pathogen-free, FXR, germ-free, SCFA, short-chain fatty acid, LPS, lipopolysaccharide, ANS, autonomic nervous system, ANS, free fatty acid receptor, CNS, Serotonin, ASD, autism spectrum disorder, Trp, tryptophan, LPS, BBB, blood-brain barrier, IBS, irritable bowel syndrome, Central nervous system, FFAR, autism spectrum disorder, CNS, central nervous system, Stress, digestive system, ASD, 03 medical and health sciences, G protein-coupled bile acid receptor, FXR, farnesoid X receptor, enteroendocrine cell, IBS, fibroblast growth factor, medicine, Endocrine system, ECC, Secretion, tryptophan, secondary bile acid, BGM, brain-gut-microbiome, enterochromaffin cell, Intestinal permeability, Hepatology, G-protein–coupled receptor, autonomic nervous system, blood-brain barrier, medicine.disease, biology.organism_classification, 2BA, central nervous system, SCFA, gastrointestinal, FGF, fibroblast growth factor, GF, germ-free, Autonomic nervous system, 030104 developmental biology, glucagon-like peptide-1, GLP-1, short-chain fatty acid, 2BA, secondary bile acid, Neuroscience, BBB, 030217 neurology & neurosurgery, farnesoid X receptor, Hormone, Intestinal Permeability
وصف الملف: application/pdf
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المؤلفون: Paul Trayhurn, Gareth Denyer
المصدر: Journal of Nutritional Science
مصطلحات موضوعية: Inflammation, chemistry.chemical_classification, Nutrition and Dietetics, Microarray, Microarrays, Microarray analysis techniques, Endocrinology, Diabetes and Metabolism, Focus on Nutrition, GPR120, Fatty acid, Biology, Cell biology, chemistry, Free fatty acid receptor 1, Immunology, Adipocytes, Fatty acid receptors, GPR, G-protein-coupled receptor, DNA microarray, Receptor, Food Science, Polyunsaturated fatty acid