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    المصدر: JHEP reports : innovation in hepatology. 4(9)

    مصطلحات موضوعية: ALT, alanine aminotransferase, APAF1, apoptotic peptidase activating factor 1, ASK1, apoptosis signal-regulating kinase 1, AST, aspartate aminotransferase, Apoptosis, BMM, bone marrow-derived macrophage, CXCL-10, C-X-C motif chemokine ligand 10, CYLD, cyclindromatosis, ChIP, chromatin immunoprecipitation, DAMP, damage-associated molecular pattern, DUB, deubiquitinating enzyme, ER, endoplasmic reticulum, ES, embryonic stem, G3BP1, G3BP1, Ras GTPase-activating protein-binding protein 1, GCLC, glutamate-cysteine ligase catalytic subunit, GCLM, glutamate-cysteine ligase regulatory subunit, IHC, immunohistochemistry, INF-β, interferon-β, IR, ischaemia/reperfusion, IRF3, IRF3, interferon regulatory factor 3, IRF7, IFN-regulating transcription factor 7, IRI, ischaemia/reperfusion injury, Innate immunity, KO, knockout, LPS, lipopolysaccharide, Liver inflammation, Lyz2, Lysozyme 2, MCP-1, monocyte chemoattractant protein 1, NOX2, NADPH oxidase 2, NOX4, NADPH oxidase 4, NQO1, NAD(P)H quinone dehydrogenase 1, NRF2, nuclear factor (erythroid-derived 2)-like 2, NS, non-specific, Necroptosis, OASL1, 2′, 5′oligoadenylate synthetase-like 1, PAMP, pathogen-derived molecular pattern, RIPK3, receptor-interacting serine/threonine-protein kinase 3, ROS, reactive oxygen species, STING, STING, stimulator of interferon genes, TBK1, TANK-binding kinase 1, TLR4, Toll-like receptor 4, TNF-α, tumour necrosis factor-alpha, TRX, thioredoxin, TSS, transcription start sites, TXNIP, thioredoxin-interacting protein, TXNIPFL/FL, floxed TXNIP, TXNIPM-KO, myeloid-specific TXNIP KO, UTR, untranslated region, sALT, serum ALT, sAST, serum AST, siRNA, small interfering RNA, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being

    وصف الملف: application/pdf

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    Academic Journal

    المؤلفون: Li Y, Ma S, Wang Z, Shi M, Zeng R, Yao Y

    المصدر: Journal of Inflammation Research, Vol Volume 17, Pp 527-540 (2024)

    وصف الملف: electronic resource

    Relation: https://www.dovepress.com/gclc-as-a-marker-for-injured-distal-nephron-in-ischemia-reperfusion-in-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

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    Relation: The impact of genetic polymorphisms in glutamate-cysteine ligase, a key enzyme of glutathione biosynthesis, on Ischemic stroke risk and brain infarct size / A. Polonikov [et al.] // Life. - 2022. - Vol.12, №4.-Art. 602. - Doi:10.3390/ life12040602. - URL: https://www.mdpi.com/2075-1729/12/4/602.; http://dspace.bsu.edu.ru/handle/123456789/54601