المؤلفون: Cecilia Pozzi, Alessandro Pratesi, Stefano Mangani, Paola Turano, Silvia Ciambellotti, G. Tassone

المصدر: Chemistry – A European Journal. 27:14690-14701

مصطلحات موضوعية: Iron, Oxide, Ferroxidase activity, Ferric Compounds, Redox, Catalysis, chemistry.chemical_compound, ferroxidase sites, medicine, Animals, Humans, Binding site, Binding Sites, accessory transient sites, biology, Chemistry, Organic Chemistry, ferroxidase reactions, human mitochondrial ferritin, MITOCHONDRIAL FERRITIN, Ceruloplasmin, General Chemistry, Ferritin, Apoferritins, Ferritins, biology.protein, Biophysics, Ferric, Oxidation-Reduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92112bd4e50cbb38cc8488356efedb7c
https://doi.org/10.1002/chem.202102270

المؤلفون: Pasquale Linciano, Cecilia Pozzi, G. Tassone, Stefano Mangani, G. Landi, Maria Paola Costi

المصدر: Acta Crystallographica Section D Structural Biology. 76:558-564

مصطلحات موضوعية: Models, Molecular, Indoles, Stereochemistry, human African trypanosomiasis, Trypanosoma brucei brucei, Protozoan Proteins, Trypanosoma brucei, Cofactor, Antiparasitic drugs, High-resolution crystal structure, Human African trypanosomiasis, Pteridine reductase 1, Tricyclic compound, Structure-Activity Relationship, pteridine reductase 1, 03 medical and health sciences, tricyclic compound, 0302 clinical medicine, Structural Biology, Dihydrofolate reductase, medicine, African trypanosomiasis, Enzyme Inhibitors, Ternary complex, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, biology, Bicyclic molecule, Chemistry, biology.organism_classification, medicine.disease, Trypanocidal Agents, antiparasitic drugs, high-resolution crystal structure, 3. Good health, Drug Design, 030220 oncology & carcinogenesis, biology.protein, Trypanosoma, Oxidoreductases, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f707f376de14203b4b26fd428e0eef
https://doi.org/10.1107/s2059798320004891

المؤلفون: Cecilia Pozzi, Maurizio Orlandini, Benedetta Carlotti, Fausto Ortica, Massimo Olivucci, Loredana Latterini, Annalisa Reale, Laura Salvini, Gianluca Giorgi, Stefano Mangani, Marco Paolino, Xuchun Yang, Andrea Cappelli, G. Tassone, Federico Galvagni

المصدر: Chembiochem

مصطلحات موضوعية: Models, Molecular, Morita-Baylis-Hillman adducts, Rhodopsin, site-specific reactions, Receptors, Retinoic Acid, Retinoic acid, Optogenetics, Crystallography, X-Ray, Biochemistry, PYP-like chromophores, Article, light-sensitive proteins, chemistry.chemical_compound, Synthetic biology, Retinoic acid binding, Molecular Biology, Molecular Structure, biology, synthetic xanthopsin-like proteins, Organic Chemistry, Stereoisomerism, Transporter, Chromophore, Combinatorial chemistry, In vitro, chemistry, biology.protein, Molecular Medicine, Click Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c495be6a4930178e4530bc4fa123347b
http://hdl.handle.net/11365/1186435

المؤلفون: Pasquale Linciano, Michele Tonelli, Cecilia Pozzi, Valeria Francesconi, Stefano Mangani, G. Landi, Lorenzo Tagliazucchi, G. Tassone, Maria Paola Costi

المصدر: Pharmaceuticals
Volume 14
Issue 7
Pharmaceuticals, Vol 14, Iss 636, p 636 (2021)

مصطلحات موضوعية: Chagas disease, Cycloguanil, dual inhibitor, Trypanosoma brucei, structure–activity relationship, pteridine reductase, antifolate drug, Pharmaceutical Science, Pharmacology, cycloguanil, Article, 03 medical and health sciences, chemistry.chemical_compound, Pharmacy and materia medica, dihydrofolate reductase, Drug Discovery, Dihydrofolate reductase, parasitic diseases, medicine, 030304 developmental biology, X-ray crystallography, 0303 health sciences, biology, 030306 microbiology, Chemistry, biology.organism_classification, medicine.disease, 3. Good health, Pteridine reductase, Antifolate drug, Derivatives, Dual inhibitor, Pyrimethamine, Structure–activity relationship, RS1-441, pyrimethamine, derivatives, Trypanosoma, biology.protein, Molecular Medicine, Medicine, medicine.drug, Fexinidazole

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a992b6c88c5fd9ab5e2905b6b6b2b6e

المؤلفون: Massimo Olivucci, Maurizio Orlandini, G. Tassone, Cecilia Pozzi

المصدر: Biomolecules
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 645, p 645 (2021)

مصطلحات موضوعية: Models, Molecular, Bile acids, Chicken liver bile acid‐binding protein, Cholic acid, Fatty acid‐binding protein, High‐resolution crystal structure, X‐ray crystallography, Amino Acid Sequence, Animals, Bile Acids and Salts, Binding Sites, Carrier Proteins, Chickens, Cholic Acid, Crystallography, X-Ray, Drug Delivery Systems, Liver, Membrane Glycoproteins, Protein Binding, Recombinant Proteins, Bile acid binding, Biochemistry, law.invention, chemistry.chemical_compound, Models, law, fatty acid-binding protein, 0303 health sciences, Crystallography, Photoswitch, Chemistry, 030302 biochemistry & molecular biology, QR1-502, cholic acid, Recombinant DNA, chicken liver bile acid-binding protein, Drug carrier, Cell signaling, Microbiology, Fatty acid-binding protein, Article, 03 medical and health sciences, Affinity chromatography, Molecular Biology, 030304 developmental biology, X-ray crystallography, bile acids, Molecular, X-Ray, high-resolution crystal structure

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2402c1ed5a33278253471661de4508a

المؤلفون: Cecilia Pozzi, Stefano Mangani, Maurizio Botta, G. Tassone

المصدر: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:1190-1198

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, ATPase, Protozoan Proteins, Biophysics, Biochemistry, Leishmania braziliensis, Analytical Chemistry, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, ATP hydrolysis, Heat shock protein, Humans, Selectivity, HSP90 Heat-Shock Proteins, Heat shock protein 90, Cloning, Molecular, Nucleotides, Protozoan parasites, X-ray crystallography, Molecular Biology, Site-directed mutagenesis, chemistry.chemical_classification, Binding Sites, biology, Chemistry, Hydrolysis, biology.organism_classification, Hsp90, 030104 developmental biology, Enzyme, 030220 oncology & carcinogenesis, Chaperone (protein), Mutagenesis, Site-Directed, biology.protein, Brazil, Molecular Chaperones, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fceae29970a9fdfcafba2053ffaf07cc
https://doi.org/10.1016/j.bbapap.2018.09.005

المؤلفون: Federica Verdirosa, G. Tassone, Pierre-Alexis Conde, Katja Becker, Caitlyn A. Thomas, Jean-François Hernandez, Stefano Mangani, Manuela Benvenuti, Alice Legru, Michael W. Crowder, Melissa Dillenberger, Laurent Gavara, Jean Denis Docquier, Filomena Sannio, Guillaume Bossis, Cecilia Pozzi

المصدر: European Journal of Medicinal Chemistry. 226:113873

مصطلحات موضوعية: Klebsiella pneumoniae, Stereochemistry, Substituent, Context (language use), Sulfides, beta-Lactamases, Structure-Activity Relationship, chemistry.chemical_compound, Thioether, Drug Discovery, Humans, Alkyl, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Aryl, Organic Chemistry, Thiones, General Medicine, Triazoles, Ligand (biochemistry), biology.organism_classification, Enzyme, beta-Lactamase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e28aef8847969e5936f4f5d2fcc4503
https://doi.org/10.1016/j.ejmech.2021.113873

المؤلفون: G. Tassone, Andrei Leitão, Carlos A. Montanari, Mattia Mori, Júlio César Borges, Maurizio Botta, Sérgio L. Ramos, Fernanda Aparecida Heleno Batista

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 639-649 (2020)

مصطلحات موضوعية: Hsp90, RM1-950, 01 natural sciences, Microbiology, inhibitors, parasitic diseases, Drug Discovery, medicine, leishmaniasis, Pharmacology, biology, 010405 organic chemistry, Neglected Disease, food and beverages, Leishmaniasis, General Medicine, biology.organism_classification, medicine.disease, Leishmania braziliensis, Small molecule, molecular modelling, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Chaperone (protein), biology.protein, Protozoa, Therapeutics. Pharmacology, fluorescence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3285e7e93987640c3a9c8111b42723c

المؤلفون: Nicolas Sprynski, Simon Leiris, Kirsty Holden, Srinivasu Pothukanuri, Martin Everett, Agustina Llanos, Manuela Benvenuti, Srinivas Vasa, David T. Davies, Francesca Marcoccia, Richard Elliot, Magdalena Zalacain, Clarisse Lozano, Peter Warn, David Pallin, Cecilia Pozzi, Justine Bousquet, Ian Morrissey, Marc Lemonnier, Ravindar Valige, Bhaskar Kummari, G. Tassone, Jean Denis Docquier, Stefano Mangani, Jérôme Castandet, Ramesh Pattipati, Laethitia Alibaud, Cyntia De Piano

مصطلحات موضوعية: 0303 health sciences, Carbapenem, biology, Chemistry, Avibactam, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, 01 natural sciences, Meropenem, 0104 chemical sciences, Acinetobacter baumannii, Microbiology, Serine, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Antibiotic resistance, Drug Discovery, polycyclic compounds, medicine, Molecular Medicine, Structure–activity relationship, Beta-Lactamase Inhibitors, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d974eab718ab77cc1b0732365a12c9e0
http://hdl.handle.net/11365/1125122

المؤلفون: Leire Iralde-Lorente, Maurizio Botta, Mario Chiariello, Claire C. Munier, G. Tassone, Cecilia Pozzi, Perry Matthew, Adriano Angelucci, Stefano Mangani, Lorenzo Franci, Ylenia Cau

المصدر: Proceedings, Vol 22, Iss 1, p 17 (2019)

مصطلحات موضوعية: ABL, Chemistry, Protein-protein interactions, Motility, lcsh:A, Adhesion, Small molecule, c-Abl, Protein–protein interaction, Cell biology, hemic and lymphatic diseases, chronic myeloid leukemia (CML), lcsh:General Works, Tyrosine kinase, neoplasms, 14-3-3

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918dfc077f4dd8adb111b1b36ffc407f
https://www.mdpi.com/2504-3900/22/1/17

المؤلفون: G. Tassone, Maria Paola Costi, Stefania Ferrari, Rosaria Luciani, Stefano Mangani, Cecilia Pozzi

المصدر: Molecules, Vol 24, Iss 7, p 1257 (2019)
Molecules
Volume 24
Issue 7
Molbank 24(7), 1257-(2019). doi:10.3390/molecules24071257

مصطلحات موضوعية: Pharmaceutical Science, thymidylate synthase, 010402 general chemistry, 01 natural sciences, Thymidylate synthase, Cofactor, Enterococcus faecalis, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, Drug Discovery, Transferase, Physical and Theoretical Chemistry, Pathogen, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA synthesis, biology, Organic Chemistry, selectivity, Substrate (chemistry), biology.organism_classification, x-ray structure, 0104 chemical sciences, 3. Good health, half-site reactivity, Enzyme, chemistry, Biochemistry, Chemistry (miscellaneous), ddc:540, biology.protein, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7f31eeb983a1a57f904190c72844c8
https://www.mdpi.com/1420-3049/24/7/1257

المؤلفون: Ciolo A. Paolino, G. Tarei, G. Tassone, J. M. Muller, E. Costa, M. Feroci, F. Frontera, L. Piro

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://arxiv.org/pdf/astro-ph/0001011v1.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.257.8278; http://arxiv.org/pdf/astro-ph/0001011v1.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.257.8278
http://arxiv.org/pdf/astro-ph/0001011v1.pdf

المؤلفون: C. Sforza, G. A Beltramini, A. R. Bolzoni, G. Ballabio, T. Miraglia, G. Tassone, I. Annese, M. Bisighini, A. Cazzanica, G. Dalai, A. C. Mousa Urbina, M. Galli, M. Zago.

المساهمون: C. Sforza, G. A Beltramini, A.R. Bolzoni, G. Ballabio, T. Miraglia, G. Tassone, I. Annese, M. Bisighini, A. Cazzanica, G. Dalai, A.C. Mousa Urbina, M. Galli, M. Zago

مصطلحات موضوعية: Settore BIO/16 - Anatomia Umana, Settore MED/29 - Chirurgia Maxillofacciale, Settore ING-INF/06 - Bioingegneria Elettronica e Informatica

Relation: volume:123; issue:S1; firstpage:204; lastpage:204; numberofpages:1; journal:ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY; http://hdl.handle.net/2434/601007

الاتاحة: http://hdl.handle.net/2434/601007

المؤلفون: Mattia Mori, Lorenzo Franci, Daniela Valensin, Letizia Clementi, Leire Iralde-Lorente, Adriano Angelucci, Maurizio Botta, Mario Chiariello, Ylenia Cau, G. Tassone

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 657-664 (2019)

مصطلحات موضوعية: 14-3-3, 4-aminoantipyrine, c-Abl, leukaemia, protein–protein interaction, 14-3-3 Proteins, Antineoplastic Agents, Benzamides, Cell Proliferation, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, HeLa Cells, Humans, K562 Cells, Molecular Structure, Protein Binding, Pyrazoles, Structure-Activity Relationship, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Plasma protein binding, Drug Screening Assays, 01 natural sciences, law.invention, Protein–protein interaction, Dose-Response Relationship, law, Drug Discovery, Structure–activity relationship, 14-3-3 protein, 010405 organic chemistry, Chemistry, Cell growth, lcsh:RM1-950, Antitumor, General Medicine, Nuclear magnetic resonance spectroscopy, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, lcsh:Therapeutics. Pharmacology, Biochemistry, Recombinant DNA, Drug, K562 cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d7e3bed3b88225dda4790ae10c0305
https://pubmed.ncbi.nlm.nih.gov/30727786

المؤلفون: G. Tassone, Stefano Mangani, Cecilia Pozzi, Ludovica Lopresti

المصدر: Molecules, Vol 24, Iss 8, p 1638 (2019)
Molecules

مصطلحات موضوعية: Methyltransferase, Molecular Sequence Data, Pharmaceutical Science, flavin-dependent thymidylate synthase, Flavin group, Review, thymidylate synthase, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Thymidylate synthase, Cofactor, Protein Structure, Secondary, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, Flavins, Drug Discovery, inhibitors, medicine, Humans, Amino Acid Sequence, Physical and Theoretical Chemistry, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Organic Chemistry, selectivity, Pathogenic bacteria, Methyltransferases, biology.organism_classification, 0104 chemical sciences, Enzyme, Mechanism of action, Biochemistry, Chemistry (miscellaneous), half-site reactivity, biology.protein, Molecular Medicine, mechanism of action, medicine.symptom, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2500c9958ea77e7633de988cd430cf
http://hdl.handle.net/11365/1072169

المؤلفون: E. Y. Taleballah, G. Zhao, L. G. Bertoldi, G. Tassone, M.. Piemontese, F. J. Sita, N. Crawford

المصدر: Day 4 Thu, May 03, 2018.

مصطلحات موضوعية: Engineering, Expediting, Petroleum engineering, Completion (oil and gas wells), business.industry, Drilling, Submarine pipeline, business, Subsea

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad704cffaab84d0c08e70ed9dcc4ca30
https://doi.org/10.4043/28888-ms

المؤلفون: Stefano Mangani, Cecilia Pozzi, G. Tassone

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Computational biology, Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Pteridine reductase, medicine, African trypanosomiasis, Neglected tropical diseases, X-ray crystallography, Heat shock proteins, Drug discovery, Organic Chemistry, Rational design, Leishmaniasis, medicine.disease, Protozoan parasite, Structure-based drug discovery, 030104 developmental biology, 030220 oncology & carcinogenesis, Malaria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95de526786da3c256f1612a9bb697bb7
https://doi.org/10.1016/bs.armc.2018.08.005

المؤلفون: G. Tassone, P. Furci, CICERO, Nicola, MARINO, Fabio, ALESCI, ALESSIO, CAVALLARO, NOVELLA, RANDO, ROSSANA, DUGO, Giacomo

المساهمون: G., Tassone, Cicero, Nicola, P., Furci, Marino, Fabio, Alesci, Alessio, Cavallaro, Novella, Rando, Rossana, Dugo, Giacomo

Relation: Riunione Nazionale SINU- Nutrizione, Attività fisica, Benessere; volume:unico; firstpage:P9; lastpage:P9; http://hdl.handle.net/11570/1905142

الاتاحة: http://hdl.handle.net/11570/1905142

المؤلفون: CICERO, Nicola, POTORTI', ANGELA GIORGIA, ALESCI, ALESSIO, DUGO, Giacomo, G. Tassone, V. Fotia

المساهمون: Cicero, Nicola, G., Tassone, Potorti', ANGELA GIORGIA, Alesci, Alessio, V., Fotia, Dugo, Giacomo

Relation: Riunione Nazionale SINU- Nutrizione, Attività fisica, Benessere; volume:Unico; firstpage:P8; lastpage:P8; http://hdl.handle.net/11570/1905143

الاتاحة: http://hdl.handle.net/11570/1905143

المؤلفون: ALESCI, ALESSIO, DE PASQUALE, ANGELA, SILVESTRI, GIUSEPPA, CICERO, Nicola, SALVO, Andrea, PERGOLIZZI, Simona, LAURIANO, Eugenia, G. Tassone

المساهمون: Alesci, Alessio, DE PASQUALE, Angela, Silvestri, Giuseppa, G., Tassone, Cicero, Nicola, Salvo, Andrea, Pergolizzi, Simona, Lauriano, Eugenia

Relation: ispartofbook:Atti della Riunione Nazionale SINU – NUTRIZIONE, ATTIVITÀ FISICA, BENESSERE; Riunione Nazionale SINU – NUTRIZIONE, ATTIVITÀ FISICA, BENESSERE; firstpage:7; lastpage:7; numberofpages:1; http://hdl.handle.net/11570/1905502

الاتاحة: http://hdl.handle.net/11570/1905502