المؤلفون: Roager, Henrik Munch, Vogt, Josef K, Kristensen, Mette, Hansen, Lea Benedicte S, Ibrügger, Sabine, Mærkedahl, Rasmus B, Bahl, Martin Iain, Lind, Mads Vendelbo, Nielsen, Rikke L, Frøkiær, Hanne, Gøbel, Rikke Juul, Landberg, Rikard, Ross, Alastair B, Brix, Susanne, Holck, Jesper, Meyer, Anne S, Sparholt, Morten H, Christensen, Anders F, Carvalho, Vera, Hartmann, Bolette, Holst, Jens Juul, Rumessen, Jüri Johannes, Linneberg, Allan, Sicheritz-Pontén, Thomas, Dalgaard, Marlene D, Blennow, Andreas, Frandsen, Henrik Lauritz, Villas-Bôas, Silas, Kristiansen, Karsten, Vestergaard, Henrik, Hansen, Torben, Ekstrøm, Claus T, Ritz, Christian, Nielsen, Henrik Bjørn, Pedersen, Oluf Borbye, Gupta, Ramneek, Lauritzen, Lotte, Licht, Tine Rask

مصطلحات موضوعية: Gut microbiota

وصف الملف: text/html

Relation: http://gut.bmj.com/cgi/content/short/68/1/83; http://dx.doi.org/10.1136/gutjnl-2017-314786

الاتاحة: http://gut.bmj.com/cgi/content/short/68/1/83
https://doi.org/10.1136/gutjnl-2017-314786

المؤلفون: Hansen, Lea Benedicte Skov, Roager, Henrik Munch, Søndertoft, Nadja Buus, Gøbel, Rikke Juul, Kristensen, Mette Bredal, Vallès-Colomer, Mireia, Vieira-Silva, Sara, Ibrügger, Sabine, Lind, Mads Vendelbo, Mærkedahl, Rasmus Baadsgaard, Bahl, Martin Iain, Madsen, Mia Linda, Havelund, Jesper, Falony, Gwen, Tetens, Inge, Nielsen, Trine, Allin, Kristine Højgaard, Frandsen, Henrik Lund, Hartmann, Bolette, Holst, Jens Juul, Sparholt, Morten H, Holck, Jesper, Blennow, Andreas, Moll, Janne Marie, Meyer, Anne S, Hoppe, Camilla, Poulsen, Jørgen H, Carvalho, Vera, Sagnelli, Domenico, Dalgaard, Marlene Danner, Christensen, Anders Fogh, Lydolph, Magnus, Ross, Alistair B, Villas-Bôas, Silas G, Brix, Susanne, Sicheritz-Pontén, Thomas, Buschard, Karsten, Linneberg, Allan René, Rumessen, Jüri Johannes, Ekstrøm, Claus Thorn, Ritz, Christian, Kristiansen, Karsten, Nielsen, H Bjørn, Vestergaard, Henrik, Færgeman, Nils J, Raes, Jeroen, Frøkiær, Hanne, Hansen, Torben, Lauritzen, Lotte, Gupta, Ramneek, Licht, Tine Rask, Pedersen, Oluf Borbye

المصدر: Hansen , L B S , Roager , H M , Søndertoft , N B , Gøbel , R J , Kristensen , M B , Vallès-Colomer , M , Vieira-Silva , S , Ibrügger , S , Lind , M V , Mærkedahl , R B , Bahl , M I , Madsen , M L , Havelund , J , Falony , G , Tetens , I , Nielsen , T , Allin , K H , Frandsen , H L , Hartmann , B , Holst , J J , Sparholt , M H , Holck ....

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfScience, Faculty of Science, Low-gluten diet, Intestinal microbiome, Dietary fibres

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/a-lowgluten-diet-induces-changes-in-the-intestinal-microbiome-of-healthy-danish-adults(32f6a287-6b33-4713-9058-05a50fee0140).html
https://doi.org/10.1038/s41467-018-07019-x
https://curis.ku.dk/ws/files/208869535/Hansen_et_al_Nature_Communications_2018_Vol_9_4630.pdf

المؤلفون: Roager, Henrik Munch, Frandsen, Henrik Lauritz, Gøbel, Rikke Juul, Pedersen, Oluf, Granato Villas-Boas, Silas, Licht, Tine Rask

المصدر: Roager , H M , Frandsen , H L , Gøbel , R J , Pedersen , O , Granato Villas-Boas , S & Licht , T R 2015 , ' The effect of gluten on the host-microbial metabolism assessed by urinary metabolomics ' , EMBL Conference 2015 , Heidelberg , Germany , 10/06/2015 - 12/06/2015 .

وصف الملف: application/pdf

الاتاحة: https://orbit.dtu.dk/en/publications/f94c52b7-de5a-4303-b9c1-05a0da40aa39
https://backend.orbit.dtu.dk/ws/files/111797542/EMBL_Abstract_Henrik_Munch_Roager_v3.pdf

المؤلفون: Ibrügger, Sabine, Gøbel, Rikke Juul, Vestergaard, Henrik, Licht, Tine Rask, Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, Ramneek, Pedersen, Oluf Borbye, Bredal, Mette, Lauritzen, Lotte

المصدر: Ibrügger , S , Gøbel , R J , Vestergaard , H , Licht , T R , Frøkiær , H , Linneberg , A R , Hansen , T , Gupta , R , Pedersen , O B , Bredal , M & Lauritzen , L 2014 , ' Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health ' , Journal of Clinical Trials , vol. 4 , no. 4 . https://doi.org/10.4172/2167-0870.1000178

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://orbit.dtu.dk/en/publications/a01fa3cb-648d-456f-9205-c04ee21f9988
https://doi.org/10.4172/2167-0870.1000178
https://backend.orbit.dtu.dk/ws/files/105335969/two_randomized_crossover_trials_assessing_the_impact_of_dietary_gluten_or_wholegrain_on_the_gut_microbiome_and_host_metabolic_health_2167_0870.1000178.pdf
http://omicsgroup.org/journals/two-randomized-crossover-trials-assessing-the-impact-of-dietary-gluten-or-wholegrain-on-the-gut-microbiome-and-host-metabolic-health-2167-0870.1000178.php?aid=30184

المؤلفون: Søndertoft, Nadja Buus, Vogt, Josef Korbinian, Arumugam, Manimozhiyan, Kristensen, Mette, Gøbel, Rikke Juul, Fan, Yong, Lyu, Liwei, Bahl, Martin I., Eriksen, Carsten, Ängquist, Lars, Frøkiær, Hanne, Hansen, Tue Haldor, Brix, Susanne, Nielsen, H. Bjørn, Hansen, Torben, Vestergaard, Henrik, Gupta, Ramneek, Licht, Tine Rask, Lauritzen, Lotte, Pedersen, Oluf Borbye

المصدر: Søndertoft , N B , Vogt , J K , Arumugam , M , Kristensen , M , Gøbel , R J , Fan , Y , Lyu , L , Bahl , M I , Eriksen , C , Ängquist , L , Frøkiær , H , Hansen , T H , Brix , S , Nielsen , H B , Hansen , T , Vestergaard , H , Gupta , R , Licht , T R , Lauritzen , L & Pedersen , O B 2020 , ' The intestinal microbiome is a co-determinant of the postprandial plasma glucose response ' , P L o S One , vol. 15 , no. 9 , e0238648 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/the-intestinal-microbiome-is-a-codeterminant-of-the-postprandial-plasma-glucose-response(c4ef4267-7d13-439f-b0d3-b10fa486869d).html
https://doi.org/10.1371/journal.pone.0238648
https://curis.ku.dk/ws/files/248767338/Sondertoft_et_al_P_L_o_S_ONE_2020_Vol_15_9_e0238648.pdf

المؤلفون: Roager, Henrik Munch, Vogt, Josef Korbinian, Kristensen, Mette Bredal, Hansen, Lea Benedicte Skov, Ibrügger, Sabine, Mærkedahl, Rasmus Baadsgaard, Bahl, Martin Iain, Lind, Mads Vendelbo, Nielsen, Rikke Linnemann, Frøkiær, Hanne, Gøbel, Rikke Juul, Landberg, Rikard, Ross, Alastair B., Brix, Susanne, Holck, Jesper, Meyer, Anne S., Sparholt, Morten H., Christensen, Anders Fogh, Carvalho, Vera, Hartmann, Bolette, Holst, Jens Juul, Rumessen, Jüri Johannes, Linneberg, Allan René, Sicheritz-Pontén, Thomas, Dalgaard, Marlene D., Blennow, Andreas, Frandsen, Henrik Lauritz, Villas-Bôas, Silas, Kristiansen, Karsten, Vestergaard, Henrik, Hansen, Torben, Ekstrøm, Claus Thorn, Ritz, Christian, Nielsen, Henrik Bjørn, Pedersen, Oluf Borbye, Gupta, Ramneek, Lauritzen, Lotte, Licht, Tine Rask

المصدر: Roager , H M , Vogt , J K , Kristensen , M B , Hansen , L B S , Ibrügger , S , Mærkedahl , R B , Bahl , M I , Lind , M V , Nielsen , R L , Frøkiær , H , Gøbel , R J , Landberg , R , Ross , A B , Brix , S , Holck , J , Meyer , A S , Sparholt , M H , Christensen , A F , Carvalho , V , Hartmann , B , Holst , J J , Rumessen , J J , Linneberg , A R , Sicheritz-Pontén , T , Dalgaard , M D , Blennow , A , Frandsen , H L , Villas-Bôas , S , Kristiansen , K , Vestergaard , H , Hansen , T , Ekstrøm , C T , Ritz , C , Nielsen , H B , Pedersen , O B , Gupta , R , Lauritzen , L & Licht , T R 2019 , ' Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome : a randomised cross-over trial ' , Gut , vol. 68 , no. 1 , pp. 83-93 .

مصطلحات الفهرس: Colonic microflora, Diet, Immune response, Inflammation, Obesity, Metabolomics, Interleukin-6/blood, Blood Glucose/metabolism, Humans, Middle Aged, Gastrointestinal Microbiome, Insulin Resistance, Male, Energy Intake, Cross-Over Studies, Inflammation/blood, Feces/microbiology, Weight Loss, Denmark, Whole Grains, Adult, Female, Aged, Lipids/blood, article

URL: https://curis.ku.dk/portal/da/publications/whole-grainrich-diet-reduces-body-weight-and-systemic-lowgrade-inflammation-without-inducing-major-changes-of-the-gut-microbiome(3635f562-cbee-4d27-803f-cc07b9f15d25).html
https://doi.org/10.1136/gutjnl-2017-314786
https://curis.ku.dk/ws/files/209707730/Roager_et_al_Gut_2018_Vol_68_1_83_93.pdf

المؤلفون: Verger, Eric, Armstrong, Patrice, Nielsen, Trine, Chakaroun, Rima, Aron-Wisnewsky, Judith, Gøbel, Rikke Juul, Schütz, Tatjana, Delaere, Fabien, Gausseres, Nicolas, Clément, Karine, Holmes, Bridget

المساهمون: Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Danone Nutricia Research Palaiseau, France, Centre Daniel Carasso Palaiseau, France, University of Copenhagen = Københavns Universitet (UCPH), Leipzig University / Universität Leipzig, Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), MetaCardis Consortium: Fabrizio Andreelli, Matthias Bluher, Eric Bruckert, Philippe Giral, Xavier Girerd, Torben Hansen, Agnes Harteman, Gérard Helft, Jean-Sébastien Hulot, Richard Isnard, Lars Køber, Gilles Montalescot, Jean-Michel Oppert, Christine Poitou, Oluf Pedersen, Michael Stumvoll, Henrik Vestergaard, ANR-10-IAHU-0005,ICAN,Institut de Cardiologie-Métabolisme-Nutrition(2010)

المصدر: ISSN: 2212-2672 ; Journal of the Academy of Nutrition and Dietetics ; https://inserm.hal.science/inserm-03970414 ; Journal of the Academy of Nutrition and Dietetics, 2017, 117 (6), pp.878-888. ⟨10.1016/j.jand.2016.10.030⟩.

مصطلحات موضوعية: Development, Food frequency questionnaire, MetaCardis study, Portion sizes, Relative validity, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/28024800; PUBMED: 28024800

الاتاحة: https://inserm.hal.science/inserm-03970414
https://doi.org/10.1016/j.jand.2016.10.030

المؤلفون: Hoppe, Camilla, Gøbel, Rikke Juul, Kristensen, Mette Bredal, Lind, Mads Vendelbo, Matthiessen, Jeppe, Christensen, Tue, Trolle, Ellen, Fagt, Sisse, Madsen, Mia Linda, Husby, Steffen

المصدر: Hoppe , C , Gøbel , R J , Kristensen , M B , Lind , M V , Matthiessen , J , Christensen , T , Trolle , E , Fagt , S , Madsen , M L & Husby , S 2017 , ' Intake and sources of gluten in 20- to 75-year-old Danish adults : a national dietary survey ' , European Journal of Nutrition , vol. 56 , no. 1 , pp. 107-117 . https://doi.org/10.1007/s00394-015-1062-3

مصطلحات موضوعية: stat, socio

Relation: https://curis.ku.dk/portal/da/publications/intake-and-sources-of-gluten-in-20-to-75yearold-danish-adults(d06b2235-d755-4517-a10d-9d699ca61860).html

الاتاحة: https://curis.ku.dk/portal/da/publications/intake-and-sources-of-gluten-in-20-to-75yearold-danish-adults(d06b2235-d755-4517-a10d-9d699ca61860).html

المؤلفون: Lind, Mads Vendelbo, Madsen, Mia Linda, Rumessen, Jüri J, Vestergaard, Henrik, Gøbel, Rikke Juul, Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, Mette Bredal, Ross, Alastair B

المصدر: Lind , M V , Madsen , M L , Rumessen , J J , Vestergaard , H , Gøbel , R J , Hansen , T , Lauritzen , L , Pedersen , O B , Kristensen , M B & Ross , A B 2016 , ' Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome ' , Journal of Nutrition , vol. 146 , no. 10 , pp. 1991-1998 . https://doi.org/10.3945/jn.116.236398

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfScience, Faculty of Science, Celiac disease, Biomarkers, Gluten sensitivity, Gluten-related disorders, Coeliac disease, Gluten intolerance, Gluten-free diet

الاتاحة: https://curis.ku.dk/portal/da/publications/plasma-alkylresorcinols-reflect-gluten-intake-and-distinguish-between-glutenrich-and-glutenpoor-diets-in-a-population-at-risk-of-metabolic-syndrome(3b1f18b8-2f85-409e-bc26-3ec75dd9b515).html
https://doi.org/10.3945/jn.116.236398

المؤلفون: Gøbel, Rikke Juul

المصدر: Gøbel , R J 2011 , The effect of probiotic interventions on inflammation, atopic dermatitis and metabolic syndrome in children . Department of Human Nutrition, University of Copenhagen .

الاتاحة: https://curis.ku.dk/portal/da/publications/the-effect-of-probiotic-interventions-on-inflammation-atopic-dermatitis-and-metabolic-syndrome-in-children(6efd135c-ee99-4aa1-ade6-b47aa28fb5d9).html

المؤلفون: Verger, Eric O, Armstrong, Patrice, Nielsen, Trine, Chakaroun, Rima, Aron-Wisnewsky, Judith, Gøbel, Rikke Juul, Schütz, Tatjana, Delaere, Fabien, Gausseres, Nicolas, Clément, Karine, Holmes, Bridget A

المصدر: Verger , E O , Armstrong , P , Nielsen , T , Chakaroun , R , Aron-Wisnewsky , J , Gøbel , R J , Schütz , T , Delaere , F , Gausseres , N , Clément , K , Holmes , B A & MetaCardis Consortium 2017 , ' Dietary Assessment in the MetaCardis Study : Development and Relative Validity of an Online Food Frequency Questionnaire ' , Journal of the Academy of Nutrition and Dietetics , vol. 117 , no. 6 , pp. 878-888 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/dietary-assessment-in-the-metacardis-study(0f2422da-f923-4de0-a412-979deab697d1).html
https://doi.org/10.1016/j.jand.2016.10.030

المؤلفون: Gøbel, Rikke Juul, Larsen, Nadja, Jakobsen, Mogens, Mølgaard, Christian, Michaelsen, Kim F.

المصدر: Gøbel , R J , Larsen , N , Jakobsen , M , Mølgaard , C & Michaelsen , K F 2012 , ' Probiotics to adolescents with obesity : Effects on inflammation and metabolic syndrome ' , Journal of Pediatric Gastroenterology and Nutrition , vol. 55 , no. 6 , pp. 673-678 . https://doi.org/10.1097/MPG.0b013e318263066c

الاتاحة: https://curis.ku.dk/portal/da/publications/probiotics-to-adolescents-with-obesity(28f91bc3-abb7-4c37-ab8f-fcd69366feb0).html
https://doi.org/10.1097/MPG.0b013e318263066c

المؤلفون: Gøbel, Rikke Juul, Jensen, Signe Marie, Frøkiær, Hanne, Mølgaard, Christian, Michaelsen, Kim F.

المصدر: Gøbel , R J , Jensen , S M , Frøkiær , H , Mølgaard , C & Michaelsen , K F 2012 , ' Obesity, inflammation and metabolic syndrome in Danish adolescents ' , Acta Paediatrica , vol. 101 , no. 2 , pp. 192-200 . https://doi.org/10.1111/j.1651-2227.2011.02493.x

الاتاحة: https://researchprofiles.ku.dk/da/publications/obesity-inflammation-and-metabolic-syndrome-in-danish-adolescents(16705c56-ed90-4665-8c29-87876eec4355).html
https://doi.org/10.1111/j.1651-2227.2011.02493.x

المؤلفون: Larsen, Nadejda Nikolajevna, Vogensen, Finn Kvist, Gøbel, Rikke Juul, Michaelsen, Kim F., Abu Al-Soud, Waleed, Sørensen, Søren Johannes, Hansen, Lars H., Jakobsen, Mogens

المصدر: Larsen , N N , Vogensen , F K , Gøbel , R J , Michaelsen , K F , Abu Al-Soud , W , Sørensen , S J , Hansen , L H & Jakobsen , M 2011 , ' Predominant genera of fecal microbiota in children with atopic dermatitis are not altered by intake of probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07 ' , FEMS Microbiology Ecology , vol. 75 , no. 3 , pp. 482-496 . https://doi.org/10.1111/j.1574-6941.2010.01024.x

الاتاحة: https://curis.ku.dk/portal/da/publications/predominant-genera-of-fecal-microbiota-in-children-with-atopic-dermatitis-are-not-altered-by-intake-of-probiotic-bacteria-lactobacillus-acidophilus-ncfm-and-bifidobacterium-animalis-subsplactis-bi07(21bfc1fb-642e-4908-a0c2-3c4c24e02faf).html
https://doi.org/10.1111/j.1574-6941.2010.01024.x

المؤلفون: Gøbel, Rikke Juul, Larsen, Nadejda Nikolajevna, Mølgaard, Christian, Jakobsen, Mogens, Michaelsen, Kim F.

المصدر: Gøbel , R J , Larsen , N N , Mølgaard , C , Jakobsen , M & Michaelsen , K F 2010 , ' Probiotics to young children with atopic dermatitis : a randomized placebo-controlled trial ' , International Journal of Probiotics & Prebiotics , vol. 5 , no. 2 , pp. 53-60 .

الاتاحة: https://curis.ku.dk/portal/da/publications/probiotics-to-young-children-with-atopic-dermatitis(1bc74f80-a5fd-11df-928f-000ea68e967b).html

المؤلفون: Jakobsen, Mogens, Michaelsen, Kim F., Frøkiær, Hanne, Vogensen, Finn Kvist, Larsen, Nadejda Nikolajevna, Gøbel, Rikke Juul

المصدر: Jakobsen , M , Michaelsen , K F , Frøkiær , H , Vogensen , F K , Larsen , N N & Gøbel , R J 2010 , ' Probiotika ' , Maelkeritidende , bind 123 , nr. 9 , s. 10-12 .

الاتاحة: https://curis.ku.dk/portal/da/publications/probiotika(c8b2ee30-5da9-11df-928f-000ea68e967b).html

المؤلفون: Larsen, Nadja, Vogensen, Finn Kvist, Gøbel, Rikke Juul, Michaelsen, Kim F., Forssten, Sofia D., Lahtinen, Sampo J., Jakobsen, Mogens

المصدر: Larsen , N , Vogensen , F K , Gøbel , R J , Michaelsen , K F , Forssten , S D , Lahtinen , S J & Jakobsen , M 2013 , ' Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents ' , Clinical Nutrition , vol. 32 , no. 6 , pp. 935-940 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/effect-of-lactobacillus-salivarius-ls33-on-fecal-microbiota-in-obese-adolescents(918f465c-95bd-48c3-a45f-9114ec98172e).html
https://doi.org/10.1016/j.clnu.2013.02.007
http://www.sciencedirect.com/science/article/pii/S0261561413000538

المؤلفون: Larsen, Nadejda Nikolajevna, Vogensen, Finn Kvist, Gøbel, Rikke Juul, Michaelsen, Kim F., Abu Al-Soud, Waleed, Sørensen, Søren Johannes, Hansen, Lars H., Jakobsen, Mogens

المصدر: Larsen , N N , Vogensen , F K , Gøbel , R J , Michaelsen , K F , Abu Al-Soud , W , Sørensen , S J , Hansen , L H & Jakobsen , M 2011 , ' Predominant genera of fecal microbiota in children with atopic dermatitis are not altered by intake of probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07 ' , FEMS Microbiology Ecology , vol. 75 , no. 3 , pp. 482-496 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/predominant-genera-of-fecal-microbiota-in-children-with-atopic-dermatitis-are-not-altered-by-intake-of-probiotic-bacteria-lactobacillus-acidophilus-ncfm-and-bifidobacterium-animalis-subsplactis-bi07(21bfc1fb-642e-4908-a0c2-3c4c24e02faf).html
https://doi.org/10.1111/j.1574-6941.2010.01024.x

المؤلفون: Gøbel, Rikke Juul

مصطلحات الفهرس: person

URL: https://curis.ku.dk/portal/da/persons/rikke-juul-goebel(1f7c2591-4177-43c2-97d2-34125d2254e9).html

المؤلفون: Gøbel, Rikke Juul, Larsen, Nadja, Jakobsen, Mogens, Mølgaard, Christian, Michaelsen, Kim Fleischer

المصدر: Journal of Pediatric Gastroenterology & Nutrition; December 2012, Vol. 55 Issue: 6 p673-678, 6p