المؤلفون: Monika Sundqvist, Göran Duker, Ola Fjellström, Yu-ki Iwasaki, Fabrizio Giordanetto, Qing-Dong Wang, Takeshi Kato, Anita Wallin, Stanley Nattel

المصدر: Journal of Cardiovascular Electrophysiology. 25:531-536

مصطلحات موضوعية: Mibefradil, medicine.medical_specialty, business.industry, T-type calcium channel, Atrial fibrillation, Pharmacology, Placebo, medicine.disease, 3. Good health, Blockade, Electrophysiology, Pharmacotherapy, Physiology (medical), Internal medicine, cardiovascular system, medicine, Cardiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Atrial tachycardia, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::82b2d4641252de571e74fc27a54cd0f2
https://doi.org/10.1111/jce.12346

المؤلفون: M A Vos, Lukas Nalos, Marcel A.G. van der Heyden, Maaike Peschar, M. Houtman, R. van der Nagel, T.P. de Boer, Göran Duker, Martin B. Rook, Rosanne Varkevisser, Jet D.M. Beekman, Morten B. Thomsen, Peter Sartipy, Mkb Jonsson, Tab Van Veen

المصدر: British Journal of Pharmacology. 165:467-478

مصطلحات موضوعية: medicine.medical_specialty, Torsades de pointes, Dofetilide, 030204 cardiovascular system & hematology, Pharmacology, Methoxamine, Afterdepolarization, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Moxifloxacin, Internal medicine, Medicine, Repolarization, 030304 developmental biology, 0303 health sciences, business.industry, Potassium channel blocker, medicine.disease, 3. Good health, chemistry, Cardiology, E-4031, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::29ec3594e46a5edc9cb8ab49e9cc5c56
https://doi.org/10.1111/j.1476-5381.2011.01558.x

المؤلفون: Antonio Llinas, Fredrik Thorstensson, Emma Lindhardt, Ågot Högberg, Kristina Nilsson, Anders Lindqvist, Annika Åstrand, Göran Duker, Victoria Ullah, Gavin O'Mahony, Qing-Dong Wang, Pernilla Ståhlberg, Nidhal Selmi, Laurent Knerr, Fabrizio Giordanetto

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:5557-5561

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Calcium Channels, T-Type, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Acetamides, Drug Discovery, Animals, Humans, Molecular Biology, Antihypertensive Agents, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Calcium channel, Organic Chemistry, T-type calcium channel, Stereoisomerism, Calcium Channel Inhibition, Ether-A-Go-Go Potassium Channels, High-Throughput Screening Assays, Rats, Chemical evolution, Molecular Medicine, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cba3b145e5adacb5094a5344ec69713
https://doi.org/10.1016/j.bmcl.2011.06.092

المؤلفون: Ingemar Jacobson, Göran Duker, Leif Carlsson

المصدر: Journal of Pharmacological and Toxicological Methods. 63:40-46

مصطلحات موضوعية: Male, Drug, ERG1 Potassium Channel, medicine.medical_specialty, media_common.quotation_subject, Beat (acoustics), Torsades de pointes, Dofetilide, Pharmacology, Kidney, Toxicology, QT interval, Ion Channels, Methoxamine, Cell Line, Electrocardiography, Torsades de Pointes, Internal medicine, Phenethylamines, Animals, Humans, Medicine, media_common, Proarrhythmia, Sulfonamides, Models, Statistical, business.industry, Prolongation, Arrhythmias, Cardiac, Heart, Embryo, Mammalian, medicine.disease, Ether-A-Go-Go Potassium Channels, Rats, Long QT Syndrome, Cardiology, Rabbits, business, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a561f54ef1f14625e695a9933d7cab45
https://doi.org/10.1016/j.vascn.2010.04.010

المؤلفون: Göran Duker, Ingemar Jacobson, Leif Carlsson

المصدر: Trends in Pharmacological Sciences. 31:364-371

مصطلحات موضوعية: medicine.medical_specialty, Toxicology, Structural remodeling, Amiodarone, Ion Channels, Drug Delivery Systems, Internal medicine, Atrial Fibrillation, medicine, Animals, Humans, Sinus rhythm, Heart Atria, Inflammation, Pharmacology, Proarrhythmia, business.industry, Atrial fibrillation, medicine.disease, Blockade, Oxidative Stress, Safety profile, Cardiology, Calcium, business, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf0207567a5f668d031ba905c00a8f2
https://doi.org/10.1016/j.tips.2010.05.001

المؤلفون: Carl-Fredrik Mandenius, Giorgio Minotti, Tina C. Stummann, Y. Jean Pierre Valentin, Robin L. Jones, J. Magnus Fredriksson, Thomas Meyer, Marina Hasiwa, Göran Duker, Y. James Kang, Mario Beilmann, Bernd J. Zünkler, Susanne Bremer, Berengere Dumotier

المصدر: Cardiovascular Toxicology. 9:107-125

مصطلحات موضوعية: Alternative methods, Drug, medicine.medical_specialty, Cardiotoxicity, business.industry, media_common.quotation_subject, Pharmacology toxicology, Pharmacology, Toxicology, medicine, Clinical safety, Cardiology and Cardiovascular Medicine, Intensive care medicine, business, Molecular Biology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a202da502ab43233d90ace4b429a4005
https://doi.org/10.1007/s12012-009-9045-3

المؤلفون: Malin K.B. Jonsson, Marie-José Goumans, Toon A.B. van Veen, Marc A. Vos, Göran Duker, Peter Sartipy

المصدر: Expert Opinion on Drug Discovery. 4:357-372

مصطلحات موضوعية: business.industry, Drug discovery, Safety pharmacology, Cellular differentiation, Model system, Pharmacology, Bioinformatics, Efficacy, Drug development, Drug Discovery, Medicine, Stem cell, business, Pharmaceutical industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae3c6f88b64b0ebed1a6860e015a19e
https://doi.org/10.1517/17460440902794912

المؤلفون: Anna H. Persson, Sandra A.G. Visser, Lars B. Nilsson, Tomas Forsberg, Johan Gabrielsson, Anna Ollerstam, Jan-Arne Björkman, Ahmad Al-Saffar, Göran Duker

المصدر: Journal of Pharmacological and Toxicological Methods. 56:131-144

مصطلحات موضوعية: Male, Time Factors, Consciousness, Moxifloxacin, Drug Evaluation, Preclinical, Dofetilide, Toxicology, Paced Rhythm, QT interval, Beagle, Electrocardiography, Dogs, Heart Rate, Phenethylamines, medicine, Animals, Telemetry, Anesthesia, Terfenadine, Sinus rhythm, Infusions, Intravenous, Sinoatrial Node, Pharmacology, Aza Compounds, Cisapride, Sulfonamides, Dose-Response Relationship, Drug, business.industry, Cardiac Pacing, Artificial, Ether-A-Go-Go Potassium Channels, Long QT Syndrome, Models, Animal, Quinolines, Female, business, Fluoroquinolones, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4b2dc8c425cc9af7b025790a455bb1
https://doi.org/10.1016/j.vascn.2007.05.002

المؤلفون: Lars B. Nilsson, Göran Eklund, Stig Johan Wiklund, Göran Duker, Ahmad Al-Saffar, Tomas Forsberg, Johan Gabrielsson, Anna H. Persson, Anna Ollerstam, J. Magnus Fredriksson, Sandra A.G. Visser

المصدر: Journal of Pharmacological and Toxicological Methods. 55:35-48

مصطلحات موضوعية: Male, medicine.medical_specialty, Blood Pressure, Dofetilide, Toxicology, Beagle, QT interval, Electrocardiography, Dogs, Heart Rate, Internal medicine, Phenethylamines, Heart rate, medicine, Haloperidol, Animals, Telemetry, Terfenadine, Pharmacology, Cisapride, Electronic Data Processing, Sulfonamides, business.industry, Prolongation, Long QT Syndrome, Anesthesia, Cardiology, Female, business, Algorithms, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea178a75325028559170c347f76cfad
https://doi.org/10.1016/j.vascn.2006.02.009

المؤلفون: Leif Carlsson, Frida Persson, Ingemar Jacobson, Göran Duker

المصدر: Journal of Cardiovascular Pharmacology. 46:7-17

مصطلحات موضوعية: Patch-Clamp Techniques, Potassium Channels, hERG, CHO Cells, Propafenone, Pharmacology, Transfection, Membrane Potentials, Kv1.5 Potassium Channel, Cricetulus, In vivo, Cricetinae, Potassium Channel Blockers, medicine, Animals, Humans, Patch clamp, Membrane potential, Dose-Response Relationship, Drug, biology, Chemistry, Kv Channel-Interacting Proteins, Potassium channel blocker, Potassium channel, Electrophysiology, Shal Potassium Channels, biology.protein, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ab282dca1414c464bc3da5369a7864
https://doi.org/10.1097/01.fjc.0000161405.37198.c1

المؤلفون: Luc M. Hondeghem, Leif Carlsson, Göran Duker

المصدر: Circulation. 103:2004-2013

مصطلحات موضوعية: Male, medicine.medical_specialty, Potassium Channels, medicine.medical_treatment, hERG, Drug Evaluation, Preclinical, Action Potentials, Blood Pressure, In Vitro Techniques, Antiarrhythmic agent, Ventricular tachycardia, Electrocardiography, Heart Rate, Predictive Value of Tests, Torsades de Pointes, Physiology (medical), Internal medicine, Potassium Channel Blockers, Animals, Medicine, Repolarization, Cation Transport Proteins, Proarrhythmia, biology, business.industry, Arrhythmias, Cardiac, Cardiovascular Agents, Potassium channel blocker, medicine.disease, Ether-A-Go-Go Potassium Channels, Potassium channel, Electrophysiology, Potassium Channels, Voltage-Gated, Anesthesia, cardiovascular system, Cardiology, biology.protein, Rabbits, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a62856fcdd8fda064aeb1d5861cafc6
https://doi.org/10.1161/01.cir.103.15.2004

المؤلفون: Luc M. Hondeghem, Gregory J Amos, Mattias Palmer, Christina Abrahamsson, Leif Carlsson, Göran Duker

المصدر: Cardiovascular Research. 49:351-360

مصطلحات موضوعية: Male, medicine.medical_specialty, Patch-Clamp Techniques, Potassium Channels, Calcium Channels, L-Type, Physiology, Purkinje fibers, Heart Ventricles, Voltage clamp, medicine.medical_treatment, Ibutilide, Action Potentials, chemistry.chemical_element, Torsades de pointes, In Vitro Techniques, Calcium, Antiarrhythmic agent, Methoxamine, Propanolamines, Purkinje Fibers, Bridged Bicyclo Compounds, Inhibitory Concentration 50, chemistry.chemical_compound, Torsades de Pointes, Physiology (medical), Internal medicine, Alkanes, medicine, Animals, Sulfonamides, medicine.disease, Perfusion, Endocrinology, medicine.anatomical_structure, chemistry, Models, Animal, Almokalant, Rabbits, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c3875db81b020b947f7f2657dac4b5
https://doi.org/10.1016/s0008-6363(00)00259-5

المؤلفون: Christina, Abrahamsson, Corina, Dota, Bo, Skallefell, Leif, Carlsson, Lars, Frison, Anders, Berggren, Nils, Edvardsson, Göran, Duker

المصدر: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. 18(3)

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Genotype, Adrenergic beta-Antagonists, Infant, Original Articles, Middle Aged, Risk Assessment, Long QT Syndrome, Heart Conduction System, Child, Preschool, Electrocardiography, Ambulatory, Humans, Female, cardiovascular diseases, Child, Algorithms, Software, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ada3c07818cf204d7acc8047d30e8023
https://pubmed.ncbi.nlm.nih.gov/23714082

المؤلفون: Leif Carlsson, Christina Abrahamsson, Göran Duker

المصدر: Journal of Cardiovascular Electrophysiology. 7:1074-1081

مصطلحات موضوعية: Male, Lidocaine, Purkinje fibers, Nisoldipine, Action Potentials, Torsades de pointes, Pharmacology, Afterdepolarization, Propanolamines, chemistry.chemical_compound, In vivo, Physiology (medical), medicine, Animals, Repolarization, Dose-Response Relationship, Drug, business.industry, Heart, Calcium Channel Blockers, medicine.disease, medicine.anatomical_structure, chemistry, Almokalant, Rabbits, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents, Sodium Channel Blockers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1406b5f0445d9c93b5f490c5592e57e
https://doi.org/10.1111/j.1540-8167.1996.tb00483.x

المؤلفون: Ann-Kristin Nordkam, Malin Florentzson, Leif Carlsson, Annika Åstrand, Ingemar Jacobson, Emma Lindhardt, Gunilla Linhardt, Göran Duker

المصدر: Journal of cardiovascular pharmacology and therapeutics. 18(3)

مصطلحات موضوعية: Male, medicine.medical_specialty, Potassium Channels, Refractory Period, Electrophysiological, Pyridines, medicine.medical_treatment, CHO Cells, Antiarrhythmic agent, Pharmacology, Propanolamines, Random Allocation, Cricetulus, Dogs, In vivo, Internal medicine, Cricetinae, medicine, Potassium Channel Blockers, Potency, Repolarization, Animals, Humans, Pharmacology (medical), Myocytes, Cardiac, Heart Atria, Cells, Cultured, business.industry, Chinese hamster ovary cell, Hemodynamics, Atrial fibrillation, Arrhythmias, Cardiac, Drugs, Investigational, medicine.disease, Potassium channel, Recombinant Proteins, Electrophysiology, Disease Models, Animal, Cardiology, Female, Rabbits, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e17398204da61ccba4f923924e1abe8
https://pubmed.ncbi.nlm.nih.gov/23307834

المؤلفون: Antonio Llinas, Göran Duker, Annika Åstrand, Victoria Ullah, Qing-Dong Wang, Fabrizio Giordanetto, Grigorios Nikitidis, Fredrik Thorstensson, Emma Lindhardt, Anders Lindqvist, Staffan Karlsson, Nidhal Selmi, Got Högberg, Andreas Wållberg, Laurent Knerr, Åsa Lindelöf

المصدر: Bioorganicmedicinal chemistry letters. 23(1)

مصطلحات موضوعية: Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Pharmacology, Biochemistry, chemistry.chemical_compound, Calcium Channels, T-Type, Structure-Activity Relationship, Dogs, Heart Rate, Drug Discovery, medicine, Animals, Humans, Hydroxymethyl, Benzamide, Molecular Biology, Ion channel, Mibefradil, Voltage-dependent calcium channel, Calcium channel, Organic Chemistry, T-type calcium channel, Calcium Channel Inhibition, Calcium Channel Blockers, chemistry, Benzamides, Molecular Medicine, medicine.drug, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d91b9b81d442c16ed0609d98d792fd
https://pubmed.ncbi.nlm.nih.gov/23200256

المؤلفون: Göran Duker, Malin K.B. Jonsson, Sophie Demolombe, Marc A. Vos, T. A. B. van Veen

المصدر: Pharmacologytherapeutics. 127(1)

مصطلحات موضوعية: Male, medicine.medical_specialty, Modern medicine, Drug-Related Side Effects and Adverse Reactions, medicine.drug_class, media_common.quotation_subject, Gene Expression, QT interval, Electrocardiography, Risk Factors, Torsades de Pointes, Internal medicine, Medicine, Repolarization, Animals, Humans, Pharmacology (medical), Gonadal Steroid Hormones, Testosterone, Menstrual cycle, media_common, Pharmacology, Sex Characteristics, business.industry, Cardiac electrophysiology, Safety pharmacology, Arrhythmias, Cardiac, Heart, Electrophysiological Phenomena, Endocrinology, Estrogen, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90603048c31cc53356f7982241b7b18
https://pubmed.ncbi.nlm.nih.gov/20462510

المؤلفون: Göran Duker, Leif Carlsson, O. Almgren

المصدر: Journal of Cardiovascular Pharmacology. 20:458-465

مصطلحات موضوعية: Male, Quinidine, medicine.medical_specialty, Refractory period, Hemodynamics, QT interval, Propanolamines, Contractility, Electrocardiography, chemistry.chemical_compound, Dogs, Internal medicine, medicine, Animals, cardiovascular diseases, Pharmacology, Dose-Response Relationship, Drug, business.industry, Sotalol, Myocardial Contraction, medicine.anatomical_structure, chemistry, Ventricle, Anesthesia, Atrioventricular Node, cardiovascular system, Cardiology, Almokalant, Female, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc283a8a83eb7479481c16151fb54abb
https://doi.org/10.1097/00005344-199209000-00018

المؤلفون: Göran Duker, Leif Carlsson, Stanley Nattel

المصدر: Progress in biophysics and molecular biology. 98(2-3)

مصطلحات موضوعية: medicine.medical_specialty, hERG, Biophysics, Ischemia, Drug Evaluation, Preclinical, In Vitro Techniques, Ion Channels, Pericarditis, Dogs, Internal medicine, Drug Discovery, medicine, Animals, Humans, Myocytes, Cardiac, cardiovascular diseases, Adverse effect, Molecular Biology, Atrial tachycardia, biology, business.industry, Atrial fibrillation, Arrhythmias, Cardiac, medicine.disease, Electrophysiological Phenomena, Disease Models, Animal, cardiovascular system, Cardiology, biology.protein, Rabbits, medicine.symptom, business, Atrioventricular block, Anti-Arrhythmia Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76677184ba1009cf040adec23783b458
https://pubmed.ncbi.nlm.nih.gov/19038282

المؤلفون: Per-Göran Gillberg, Göran Duker, Johan Gabrielsson, Ulf Bredberg, Hugues Dolgos, Bert Benthem

المصدر: Drug discovery today. 14(7-8)

مصطلحات موضوعية: Research design, Pharmacology, Quality Control, Operations research, Dose-Response Relationship, Drug, Drug Industry, Drug-Related Side Effects and Adverse Reactions, Computer science, Safety pharmacology, Safety margin, Drugs, Investigational, Dynamic reasoning, Models, Biological, Lead (geology), Pharmaceutical technology, Species Specificity, Research Design, Drug Design, Drug Discovery, Data analysis, Animals, Humans, Pharmacokinetics, Pruning (decision trees)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1d76e94432990ef7809580afa60f6f
https://pubmed.ncbi.nlm.nih.gov/19162219