المساهمون: Masakazu Toi, Kenichi Inoue, Norikazu Masuda, Hiroji Iwata, Joohyuk Sohn, In Hae Park, Seock-Ah Im, Shin-Cheh Chen, Sotaro Enatsu, P Kellie Turner, Valérie A M André, Molly C Hardebeck, Sachi Sakaguchi, Matthew P Goetz, George W Sledge Jr, Sohn, Joo Hyuk

مصطلحات موضوعية: Aminopyridines / administration & dosage, Aminopyridines / adverse effects, Aminopyridines / pharmacokinetics, Anastrozole / administration & dosage, Anastrozole / adverse effects, Anastrozole / pharmacokinetics, Aromatase Inhibitors / administration & dosage, Aromatase Inhibitors / adverse effects, Aromatase Inhibitors / pharmacokinetics, Benzimidazoles / administration & dosage, Benzimidazoles / adverse effects, Benzimidazoles / pharmacokinetics, Breast Neoplasms / blood, Breast Neoplasms / drug therapy, Breast Neoplasms / genetics, Diarrhea / chemically induced, Diarrhea / epidemiology, Double-Blind Method, Drug Therapy, Combination, Female, Fulvestrant / administration & dosage, Fulvestrant / adverse effects, Fulvestrant / pharmacokinetics, Humans, Letrozole / administration & dosage, Letrozole / adverse effects, Letrozole / pharmacokinetics, Neutropenia / chemically induced, Neutropenia / epidemiology

Relation: CANCER SCIENCE; J00454; OAK-2022-05022; https://ir.ymlib.yonsei.ac.kr/handle/22282913/190887; T9992022298; CANCER SCIENCE, Vol.112(6) : 2381-2392, 2021-06

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/190887
https://doi.org/10.1111/cas.14877

المساهمون: Patrick Neven, Stephen R D Johnston, Masakazu Toi, Joohyuk Sohn, Kenichi Inoue, Xavier Pivot, Olga Burdaeva, Meena Okera, Norikazu Masuda, Peter A Kaufman, Han Koh, Eva-Maria Grischke, PierFranco Conte, Yi Lu, Nadine Haddad, Karla C Hurt, Antonio Llombart-Cussac, George W Sledge, Sohn, Joo Hyuk

مصطلحات موضوعية: Aminopyridines / administration & dosage, Antineoplastic Agents, Hormonal / administration & dosage, Benzimidazoles / administration & dosage, Breast Neoplasms / chemistry, Breast Neoplasms / drug therapy, Breast Neoplasms / pathology, Drug Combinations, Female, Fulvestrant / administration & dosage, Humans, Neoplasm Staging, Progression-Free Survival, Receptor, ErbB-2 / analysis, Treatment Outcome

Relation: CLINICAL CANCER RESEARCH; J00564; OAK-2022-04515; https://ir.ymlib.yonsei.ac.kr/handle/22282913/190609; https://aacrjournals.org/clincancerres/article/27/21/5801/671728/MONARCH-2-Subgroup-Analysis-of-Patients-Receiving; T202126210; CLINICAL CANCER RESEARCH, Vol.27(21) : 5801-5809, 2021-11

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/190609
https://doi.org/10.1158/1078-0432.CCR-20-4685
https://aacrjournals.org/clincancerres/article/27/21/5801/671728/MONARCH-2-Subgroup-Analysis-of-Patients-Receiving

المؤلفون: Alves, Carla L., Ehmsen, Sidse, Terp, Mikkel G., Portman, Neil, Tuttolomondo, Martina, Gammelgaard, Odd L., Hundebøl, Monique F., Kaminska, Kamila, Johansen, Lene E., Bak, Martin, Honeth, Gabriella, Bosch, Ana, Lim, Elgene, Ditzel, Henrik J.

المصدر: Alves , C L , Ehmsen , S , Terp , M G , Portman , N , Tuttolomondo , M , Gammelgaard , O L , Hundebøl , M F , Kaminska , K , Johansen , L E , Bak , M , Honeth , G , Bosch , A , Lim , E & Ditzel , H J 2021 , ' Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer ' , Nature Communications , vol. 12 , 5112 . https://doi.org/10.1038/s41467-021-25422-9

مصطلحات موضوعية: Breast Neoplasms/drug therapy, Cell Line, Tumor, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Disease Progression, Drug Resistance, Neoplasm, Drug Therapy, Combination, Female, Fulvestrant/administration & dosage, Humans, Molecular Targeted Therapy, Protein Kinase Inhibitors/administration & dosage, Proto-Oncogene Proteins c-akt/genetics

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/16ebb9be-b3ba-4857-9d6b-45c685175b25
https://doi.org/10.1038/s41467-021-25422-9

المؤلفون: Pancholi, Sunil, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Nikitorowicz-Buniak, Joanna, Ressa, Anna, Gao, Qiong, Leal, Mariana Ferreira, Bhamra, Amandeep, Thornhill, Allan, Morisset, Ludivine, Montaudon, Elodie, Sourd, Laura, Fitzpatrick, Martin, Altelaar, Maarten, Johnston, Stephen R, Marangoni, Elisabetta, Dowsett, Mitch, Martin, Lesley-Ann

المساهمون: Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

مصطلحات موضوعية: Animals, Antineoplastic Combined Chemotherapy Protocols/pharmacology, Breast Neoplasms/genetics, Cell Line, Tumor, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 6/genetics, Drug Resistance, Neoplasm/drug effects, Female, Fulvestrant/administration & dosage, Humans, MCF-7 Cells, Mice, Inbred BALB C, Nude, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Pyridines/pharmacology, RNA Interference, Receptors, Estrogen/genetics, Retinoblastoma Protein/genetics, Tamoxifen/administration & dosage, Xenograft Model Antitumor Assays/methods

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/410287

الاتاحة: https://dspace.library.uu.nl/handle/1874/410287

المؤلفون: Jones, Robert, Casbard, Angela, Carucci, Margherita, Cox, Catrin, Butler, Rachel, Alchami, Fouad, Madden, Tracie-Ann, Bale, Catherine, Bezecny, Pavel, Joffe, Johnathan, Moon, Sarah, Twelves, Chris, Venkitaraman, Ramachandran, Waters, Simon, Foxley, Andrew, Howell, Sacha

المصدر: Jones , R , Casbard , A , Carucci , M , Cox , C , Butler , R , Alchami , F , Madden , T-A , Bale , C , Bezecny , P , Joffe , J , Moon , S , Twelves , C , Venkitaraman , R , Waters , S , Foxley , A & Howell , S 2020 , ' Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION) : a multicentre, randomised, controlled, phase 2 trial ' , The Lancet Oncology ....

مصطلحات موضوعية: Adult, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Aromatase Inhibitors/pharmacology, Breast Neoplasms/drug therapy, Carcinoma, Ductal, Breast/drug therapy, Lobular/drug therapy, Double-Blind Method, Drug Resistance, Neoplasm/drug effects, Female, Follow-Up Studies, Fulvestrant/administration & dosage, Humans, Middle Aged, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasm Recurrence, Local/drug therapy, Prognosis, Pyrimidines/administration & dosage, Pyrroles/administration & dosage, Receptors, Estrogen/metabolism, Salvage Therapy, Survival Rate, ResearchInstitutes_Networks_Beacons/mcrc

الاتاحة: https://research.manchester.ac.uk/en/publications/b253c20e-1d0d-4475-a468-3784a1027b23
https://doi.org/10.1016/S1470-2045(19)30817-4

المؤلفون: Alves, Carla Maria Lourenco, Elias, Daniel, Lyng, Maria Bibi, Bak, Martin, Ditzel, Henrik

المصدر: Alves , C M L , Elias , D , Lyng , M B , Bak , M & Ditzel , H 2018 , ' SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer ' , Breast Cancer Research , vol. 20 , 60 . https://doi.org/10.1186/s13058-018-0988-9

مصطلحات موضوعية: Endocrine resistance, Epithelial-mesenchymal transition, Estrogen receptor-positive breast cancer, Fulvestrant, SNAI2, Antineoplastic Agents, Hormonal/administration & dosage, Fulvestrant/administration & dosage, Humans, Middle Aged, Snail Family Transcription Factors/genetics, Neoplasm Metastasis, Estrogen Receptor alpha/genetics, MCF-7 Cells, Drug Resistance, Neoplasm/genetics, Epithelial-Mesenchymal Transition/drug effects, Adult, Female, Aged, Cell Proliferation/drug effects, Gene Expression Regulation, Neoplastic/genetics, Breast Neoplasms/drug therapy

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/c9785f56-a64a-4163-9f65-0137f9d9b5f1

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/c9785f56-a64a-4163-9f65-0137f9d9b5f1
https://doi.org/10.1186/s13058-018-0988-9
https://findresearcher.sdu.dk/ws/files/141819899/Alves_et_al_2018_Breast_Cancer_Research.pdf
https://rdcu.be/01iV

المؤلفون: Caffa, Irene, Spagnolo, Vanessa, Vernieri, Claudio, Valdemarin, Francesca, Becherini, Pamela, Wei, Min, Brandhorst, Sebastian, Zucal, Chiara, Driehuis, Else, Ferrando, Lorenzo, Piacente, Francesco, Tagliafico, Alberto, Cilli, Michele, Mastracci, Luca, Vellone, Valerio G, Piazza, Silvano, Cremonini, Anna Laura, Gradaschi, Raffaella, Mantero, Carolina, Passalacqua, Mario, Ballestrero, Alberto, Zoppoli, Gabriele, Cea, Michele, Arrighi, Annalisa, Odetti, Patrizio, Monacelli, Fiammetta, Salvadori, Giulia, Cortellino, Salvatore, Clevers, Hans, De Braud, Filippo, Sukkar, Samir G, Provenzani, Alessandro, Longo, Valter D, Nencioni, Alessio

المساهمون: CMM Sectie Molecular Cancer Research, Child Health, Regenerative Medicine and Stem Cells, Cancer, Hubrecht Institute with UMC

مصطلحات موضوعية: Animals, Biological Factors/blood, Breast Neoplasms/diet therapy, Diet Therapy/methods, Diet, Healthy/methods, Disease Models, Animal, Disease Progression, Drug Resistance, Neoplasm/drug effects, Early Growth Response Protein 1/metabolism, Fasting/physiology, Female, Fulvestrant/administration & dosage, Humans, Insulin-Like Growth Factor I/metabolism, Insulin/blood, Leptin/blood, MCF-7 Cells, Mice, Inbred NOD, SCID, PTEN Phosphohydrolase/metabolism, Piperazines/administration & dosage, Pyridines/administration & dosage, Receptors, Estrogen, Progesterone, Tamoxifen/adverse effects

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/441128

الاتاحة: https://dspace.library.uu.nl/handle/1874/441128

المؤلفون: Slamon, Dennis J., Neven, Patrick, Chia, Stephen, Fasching, Peter A., De Laurentiis, Michelino, Im, Seock-Ah, Petrakova, Katarina, Bianchi, Giulia V., Esteva, Francisco J., Martin, Miguel, Nusch, Arnd, Sonke, Gabe S., De la Cruz-Merino, Luis, Beck, J. Thaddeus, Pivot, Xavier, Sondhi, Manu, Wang, Yingbo, Chakravartty, Arunava, Rodriguez-Lorenc, Karen, Taran, Tetiana, Jerusalem, Guy

المصدر: The New England journal of medicine, 382 (6), 514-524 (2020)

مصطلحات موضوعية: Aged, Aminopyridines/administration & dosage/adverse effects, Antineoplastic Combined Chemotherapy Protocols/adverse effects/therapeutic use, Breast Neoplasms/drug therapy/mortality, Drug Administration Schedule, Female, Fulvestrant/administration & dosage/adverse effects, Humans, Kaplan-Meier Estimate, Middle Aged, Postmenopause, Progression-Free Survival, Purines/administration & dosage/adverse effects, Receptor, ErbB-2, Receptors, Estrogen, Progesterone, oncology, Human health sciences, Sciences de la santé humaine, Oncologie

Relation: urn:issn:0028-4793; urn:issn:1533-4406; https://orbi.uliege.be/handle/2268/245119; info:hdl:2268/245119; info:pmid:31826360

الاتاحة: https://orbi.uliege.be/handle/2268/245119
https://doi.org/10.1056/NEJMoa1911149