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1Academic Journal
المؤلفون: Foulkes, Caio1 (AUTHOR), Friedrich, Nikolas1 (AUTHOR), Ivan, Branislav1 (AUTHOR), Stiegeler, Emanuel1 (AUTHOR), Magnus, Carsten1 (AUTHOR), Schmidt, Daniel1 (AUTHOR), Karakus, Umut1 (AUTHOR), Weber, Jacqueline1 (AUTHOR), Günthard, Huldrych F.1,2 (AUTHOR), Pasin, Chloé1,2 (AUTHOR), Rusert, Peter1 (AUTHOR), Trkola, Alexandra1 (AUTHOR) trkola.alexandra@virology.uzh.ch
المصدر: PLoS Pathogens. 1/21/2025, Vol. 21 Issue 1, p1-34. 34p.
مصطلحات موضوعية: *T cells, *HIV, *DATABASES, *IMMUNOGLOBULINS, *EPITOPES
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2Academic Journal
المؤلفون: Glögl, Matthias, Friedrich, Nikolas, Cerutti, Gabriele, Lemmin, Thomas, Kwon, Young D, Gorman, Jason, Maliqi, Liridona, Mittl, Peer R E, Hesselman, Maria C, Schmidt, Daniel, Weber, Jacqueline, Foulkes, Caio, Dingens, Adam S, Bylund, Tatsiana, Olia, Adam S, Verardi, Raffaello, Reinberg, Thomas, Baumann, Nicolas S, Rusert, Peter, Dreier, Birgit, Shapiro, Lawrence, Kwong, Peter D, Plückthun, Andreas, Trkola, Alexandra
المصدر: Glögl, Matthias; Friedrich, Nikolas; Cerutti, Gabriele; Lemmin, Thomas; Kwon, Young D; Gorman, Jason; Maliqi, Liridona; Mittl, Peer R E; Hesselman, Maria C; Schmidt, Daniel; Weber, Jacqueline; Foulkes, Caio; Dingens, Adam S; Bylund, Tatsiana; Olia, Adam S; Verardi, Raffaello; Reinberg, Thomas; Baumann, Nicolas S; Rusert, Peter; Dreier, Birgit; Shapiro, Lawrence; Kwong, Peter D; Plückthun, Andreas; Trkola, Alexandra (2023). Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nature Structural & Molecular Biology, 30(9):1323-1336.
مصطلحات موضوعية: Department of Biochemistry, Institute of Medical Virology, 610 Medicine & health, 570 Life sciences, biology
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/238813/1/41594_2023_Article_1062.pdf; info:pmid/37605043; urn:issn:1545-9985
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3Academic Journal
المؤلفون: Maliqi, Liridona, Friedrich, Nikolas, Glögl, Matthias, Schmutz, Stefan, Schmidt, Daniel, Rusert, Peter, Schanz, Merle, Zaheri, Maryam, Pasin, Chloé, Niklaus, Cyrille, Foulkes, Caio, Reinberg, Thomas, Dreier, Birgit, Abela, Irene, Peterhoff, David, Hauser, Alexandra, Kouyos, Roger D, Günthard, Huldrych F, van Gils, Marit J, Sanders, Rogier W, Wagner, Ralf, Plückthun, Andreas, Trkola, Alexandra
المصدر: Maliqi, Liridona; Friedrich, Nikolas; Glögl, Matthias; Schmutz, Stefan; Schmidt, Daniel; Rusert, Peter; Schanz, Merle; Zaheri, Maryam; Pasin, Chloé; Niklaus, Cyrille; Foulkes, Caio; Reinberg, Thomas; Dreier, Birgit; Abela, Irene; Peterhoff, David; Hauser, Alexandra; Kouyos, Roger D; Günthard, Huldrych F; van Gils, Marit J; Sanders, Rogier W; Wagner, Ralf; Plückthun, Andreas; Trkola, Alexandra (2023). Assessing immunogenicity barriers of the HIV-1 envelope trimer. NPJ vaccines, 8(1):148.
مصطلحات موضوعية: Clinic for Infectious Diseases, Institute of Medical Virology, Department of Biochemistry, 610 Medicine & health, 570 Life sciences, biology
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/238295/1/ZORA238295.pdf; info:pmid/37777519; urn:issn:2059-0105
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4Academic Journal
المؤلفون: Friedrich, Nikolas, Stiegeler, Emanuel, Glögl, Matthias, Lemmin, Thomas, Hansen, Simon, Kadelka, Claus, Wu, Yufan, Ernst, Patrick, Maliqi, Liridona, Foulkes, Caio, Morin, Mylène, Eroglu, Mustafa, Liechti, Thomas, Ivan, Branislav, Reinberg, Thomas, Schaefer, Jonas V, Karakus, Umut, Ursprung, Stephan, Mann, Axel, Rusert, Peter, Kouyos, Roger D, Robinson, John A, Günthard, Huldrych F, Plückthun, Andreas, Trkola, Alexandra
المصدر: essn: 2041-1723 ; nlmid: 101528555
مصطلحات موضوعية: Antibodies, Neutralizing, Cell Line, Tumor, Epitopes, HEK293 Cells, HIV Antibodies, HIV-1, Humans, Immunoglobulin G, Molecular Docking Simulation, Molecular Dynamics Simulation, Mutation, Protein Binding, Protein Conformation, env Gene Products, Human Immunodeficiency Virus
وصف الملف: application/pdf
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5Academic Journal
المؤلفون: Caillat, Christophe, Guilligay, Delphine, Torralba, Johana, Friedrich, Nikolas, Nieva, José Luis, Trkola, Alexandra, Chipot, Christophe J., Dehez, François L., Weissenhorn, Winfried
المساهمون: European Commission, Agence Nationale de la Recherche (France), Université Grenoble Alpes, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Eusko Jaurlaritza, Ministerio de Economía y Competitividad (España), Caillat, Christophe, Friedrich, Nikolas, Trkola, Alexandra, Chipot, Christophe J., Weissenhorn, Winfried
مصطلحات موضوعية: 2H10, 4E10, HIV-1, LN01, Gp41, Infectious diseases, Membrane fusion, Microbiology, Molecular biophysics, Structural biology, Virus
وصف الملف: application/pdf
Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/EC/H2020/681137; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-095624-B-C21/ES/EL RETO DE (RE)PRODUCIR SUPERANTICUERPOS NEUTRALIZANTES DEL VIH DIRIGIDOS CONTRA MPER: UN ABORDAJE MULTIDISCIPLINAR/; info:eu-repo/grantAgreement/MINECO//BIO2015-64421-R/ES/DESARROLLO DE ANTICUERPOS ANTI-GP41 RECOMBINANTES COMO NUEVOS INHIBIDORES DE LA FUSION DEL VIH/; Publisher's version; The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.7554/eLife.65005; Sí; eLife 10: e65005 (2021); http://hdl.handle.net/10261/329596; http://dx.doi.org/10.13039/501100003329; http://dx.doi.org/10.13039/501100001665; http://dx.doi.org/10.13039/501100011033; http://dx.doi.org/10.13039/501100000780; http://dx.doi.org/10.13039/501100003086; 2-s2.0-85105772575; https://api.elsevier.com/content/abstract/scopus_id/85105772575
الاتاحة: http://hdl.handle.net/10261/329596
https://doi.org/10.7554/ELIFE.65005
https://doi.org/10.13039/501100003329
https://doi.org/10.13039/501100001665
https://doi.org/10.13039/501100011033
https://doi.org/10.13039/501100000780
https://doi.org/10.13039/501100003086
https://api.elsevier.com/content/abstract/scopus_id/85105772575 -
6Academic Journal
المؤلفون: Friedrich, Nikolas, Stiegeler, Emanuel, Glögl, Matthias, Lemmin, Thomas, Hansen, Simon, Kadelka, Claus, Wu, Yufan, Ernst, Patrick, Maliqi, Liridona, Foulkes, Caio, Morin, Mylène, Eroglu, Mustafa, Liechti, Thomas, Ivan, Branislav, Reinberg, Thomas, Schaefer, Jonas V, Karakus, Umut, Ursprung, Stephan, Mann, Axel, Rusert, Peter, Kouyos, Roger D, Robinson, John A, Günthard, Huldrych F, Plückthun, Andreas, Trkola, Alexandra
المصدر: Friedrich, Nikolas; Stiegeler, Emanuel; Glögl, Matthias; Lemmin, Thomas; Hansen, Simon; Kadelka, Claus; Wu, Yufan; Ernst, Patrick; Maliqi, Liridona; Foulkes, Caio; Morin, Mylène; Eroglu, Mustafa; Liechti, Thomas; Ivan, Branislav; Reinberg, Thomas; Schaefer, Jonas V; Karakus, Umut; Ursprung, Stephan; Mann, Axel; Rusert, Peter; Kouyos, Roger D; Robinson, John A; Günthard, Huldrych F; Plückthun, Andreas; Trkola, Alexandra (2021). Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nature Communications, 12:6705.
مصطلحات موضوعية: Department of Biochemistry, Clinic for Infectious Diseases, Institute of Medical Virology, 570 Life sciences, biology, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/210334/1/Friedrich_et_al._2021.pdf; info:pmid/34795280; urn:issn:2041-1723
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7Academic Journal
المصدر: Ivan, Branislav; Sun, Zhaozhi; Subbaraman, Harini; Friedrich, Nikolas; Trkola, Alexandra (2019). CD4 occupancy triggers sequential pre-fusion conformational states of the HIV-1 envelope trimer with relevance for broadly neutralizing antibody activity. PLoS Biology, 17(1):e3000114.
مصطلحات موضوعية: Institute of Medical Virology, 570 Life sciences, biology, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/166639/1/journal.pbio.3000114.pdf; info:pmid/30650070; urn:issn:1544-9173
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8Academic Journal
المؤلفون: Kadelka, Claus, Liechti, Thomas, Ebner, Hanna, Schanz, Merle, Rusert, Peter, Friedrich, Nikolas, Stiegeler, Emanuel, Braun, Dominique L, Huber, Michael, Scherrer, Alexandra U, Weber, Jacqueline, Uhr, Therese, Kuster, Herbert, Misselwitz, Benjamin, Cavassini, Matthias, Bernasconi, Enos, Hoffmann, Matthias, Calmy, Alexandra, Battegay, Manuel, Rauch, Andri, Yerly, Sabine, Aubert, Vincent, Klimkait, Thomas, Böni, Jürg, Kouyos, Roger D, Günthard, Huldrych F, Trkola, Alexandra, Swiss HIV Cohort Study
المصدر: Kadelka, Claus; Liechti, Thomas; Ebner, Hanna; Schanz, Merle; Rusert, Peter; Friedrich, Nikolas; Stiegeler, Emanuel; Braun, Dominique L; Huber, Michael; Scherrer, Alexandra U; Weber, Jacqueline; Uhr, Therese; Kuster, Herbert; Misselwitz, Benjamin; Cavassini, Matthias; Bernasconi, Enos; Hoffmann, Matthias; Calmy, Alexandra; Battegay, Manuel; Rauch, Andri; Yerly, Sabine; Aubert, Vincent; Klimkait, Thomas; Böni, Jürg; Kouyos, Roger D; Günthard, Huldrych F; Trkola, Alexandra; Swiss HIV Cohort Study (2018). Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity. Journal of Experimental Medicine, 215(6):1589-1608.
مصطلحات موضوعية: Institute of Medical Virology, Clinic for Gastroenterology and Hepatology, Clinic for Infectious Diseases, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/151852/1/1589.full.pdf; info:pmid/29794117; urn:issn:0022-1007
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9Academic Journal
المؤلفون: Liechti, Thomas, Kadelka, Claus, Ebner, Hanna, Friedrich, Nikolas, Kouyos, Roger D, Gunthard, Huldrych F, Trkola, Alexandra
المصدر: Liechti, Thomas; Kadelka, Claus; Ebner, Hanna; Friedrich, Nikolas; Kouyos, Roger D; Gunthard, Huldrych F; Trkola, Alexandra (2018). Development of a high-throughput bead based assay system to measure HIV-1 specific immune signatures in clinical samples. Journal of Immunological Methods, 454:48-58.
مصطلحات موضوعية: Institute of Medical Virology, Clinic for Infectious Diseases, 570 Life sciences, biology, 610 Medicine & health, Immunology, Immunology and Allergy
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/145408/1/1-s2.0-S0022175917304234-main.pdf; info:pmid/29277486; urn:issn:0022-1759
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10Academic Journal
المؤلفون: Kouyos, Roger D., Rusert, Peter, Kadelka, Claus, Huber, Michael, Marzel, Alex, Ebner, Hanna, Schanz, Merle, Liechti, Thomas, Friedrich, Nikolas, Braun, Dominique L., Scherrer, Alexandra U., Weber, Jacqueline, Uhr, Therese, Baumann, Nicolas S., Leemann, Christine, Kuster, Herbert, Chave, Jean-Philippe, Cavassini, Matthias, Bernasconi, Enos, Hoffmann, Matthias, Calmy, Alexandra, Battegay, Manuel, Rauch, Andri, Yerly, Sabine, Aubert, Vincent, Klimkait, Thomas, Böni, Jürg, Metzner, Karin J., Günthard, Huldrych F., Trkola, Alexandra
المصدر: Nature ; volume 561, issue 7723, page 406-410 ; ISSN 0028-0836 1476-4687
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11Electronic Resource
المؤلفون: European Commission, Agence Nationale de la Recherche (France), Université Grenoble Alpes, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Eusko Jaurlaritza, Ministerio de Economía y Competitividad (España), Caillat, Christophe [0000-0003-2959-1871], Friedrich, Nikolas [0000-0003-0694-657X], Trkola, Alexandra [0000-0003-1013-876X], Chipot, Christophe J. [0000-0002-9122-1698], Weissenhorn, Winfried [0000-0001-5532-4959], Caillat, Christophe, Guilligay, Delphine, Torralba, Johana, Friedrich, Nikolas, Nieva, José Luis, Trkola, Alexandra, Chipot, Christophe J., Dehez, François L., Weissenhorn, Winfried
مصطلحات الفهرس: 2H10, 4E10, HIV-1, LN01, Gp41, Infectious diseases, Membrane fusion, Microbiology, Molecular biophysics, Structural biology, Virus, artículo
URL:
http://hdl.handle.net/10261/329596 https://api.elsevier.com/content/abstract/scopus_id/85105772575
Publisher's version
The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.7554/eLife.65005
Sí
info:eu-repo/grantAgreement/EC/H2020/681137
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-095624-B-C21/ES/EL RETO DE (RE)PRODUCIR SUPERANTICUERPOS NEUTRALIZANTES DEL VIH DIRIGIDOS CONTRA MPER: UN ABORDAJE MULTIDISCIPLINAR
info:eu-repo/grantAgreement/MINECO//BIO2015-64421-R/ES/DESARROLLO DE ANTICUERPOS ANTI-GP41 RECOMBINANTES COMO NUEVOS INHIBIDORES DE LA FUSION DEL VIH -
12Academic Journal
المؤلفون: Mann, Axel, Friedrich, Nikolas, Krarup, Anders, Weber, Jacqueline, Stiegeler, Emanuel, Dreier, Birgit, Pugach, Pavel, Robbiani, Melissa, Riedel, Tina, Moehle, Kerstin, Robinson, John A, Rusert, Peter, Plückthun, Andreas, Trkola, Alexandra
المصدر: Mann, Axel; Friedrich, Nikolas; Krarup, Anders; Weber, Jacqueline; Stiegeler, Emanuel; Dreier, Birgit; Pugach, Pavel; Robbiani, Melissa; Riedel, Tina; Moehle, Kerstin; Robinson, John A; Rusert, Peter; Plückthun, Andreas; Trkola, Alexandra (2013). Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors. Journal of Virology, 87(10):5868-5881.
مصطلحات موضوعية: Department of Biochemistry, Department of Chemistry, 570 Life sciences, biology, 540 Chemistry
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/79727/1/Mann_et_al._2013.pdf; https://www.zora.uzh.ch/id/eprint/79727/5/Mann_et_al_Conformation-dependent_recognition.pdf; info:pmid/23487463; urn:issn:0022-538X
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13Electronic Resource
المؤلفون: Bioquímica y biología molecular, Biokimika eta biologia molekularra, Caillat, Christophe, Guilligay, Delphine, Torralba Iturbe, Johana, Friedrich, Nikolas, Nieva Escandón, José Luis, Trkola, Alexandra, Chipot, Christophe J., Dehez, Francois L., Weissenhorn, Winfried
مصطلحات الفهرس: gp41-induced fusion, viral and cellular membranes, crystal structure of gp41 locked, fusion peptide, transmembrane, hydrophobic core, neutralizing antibodies, info:eu-repo/semantics/article
URL:
http://hdl.handle.net/10810/51495 https://elifesciences.org/articles/65005
2050-084Xhttps://elifesciences.org/articles/65005
info:eu-repo/grantAgreement/EC/H2020/681137
info:eu-repo/grantAgreement/MICINN/BIO2015-64421-R
info:eu-repo/grantAgreement/MICINN/RTI2018-095624-B-C21 -
14Electronic Resource
المؤلفون: Caillat, Christophe; https://orcid.org/0000-0003-2959-1871, Guilligay, Delphine, Torralba, Johana, Friedrich, Nikolas; https://orcid.org/0000-0003-0694-657X, Nieva, Jose L, Trkola, Alexandra; https://orcid.org/0000-0003-1013-876X, Chipot, Christophe J; https://orcid.org/0000-0002-9122-1698, Dehez, François L, Weissenhorn, Winfried; https://orcid.org/0000-0001-5532-4959
المصدر: Caillat, Christophe; Guilligay, Delphine; Torralba, Johana; Friedrich, Nikolas; Nieva, Jose L; Trkola, Alexandra; Chipot, Christophe J; Dehez, François L; Weissenhorn, Winfried (2021). Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies. eLife, 10:e65005.
مصطلحات الفهرس: Institute of Medical Virology, 570 Life sciences; biology, 610 Medicine & health, Journal Article, PeerReviewed, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion
URL:
https://www.zora.uzh.ch/id/eprint/212972/ https://www.zora.uzh.ch/id/eprint/212972
10.7554/eLife.65005 -
15Electronic Resource
المؤلفون: Friedrich, Nikolas; https://orcid.org/0000-0003-0694-657X, Stiegeler, Emanuel, Glögl, Matthias, Lemmin, Thomas, Hansen, Simon, Kadelka, Claus; https://orcid.org/0000-0002-5712-8529, Wu, Yufan, Ernst, Patrick; https://orcid.org/0000-0001-6037-1856, Maliqi, Liridona, Foulkes, Caio, Morin, Mylène, Eroglu, Mustafa, Liechti, Thomas, Ivan, Branislav, Reinberg, Thomas, Schaefer, Jonas V, Karakus, Umut, Ursprung, Stephan; https://orcid.org/0000-0003-2476-178X, Mann, Axel, Rusert, Peter, Kouyos, Roger D; https://orcid.org/0000-0002-9220-8348, Robinson, John A; https://orcid.org/0000-0001-7857-8556, Günthard, Huldrych F; https://orcid.org/0000-0002-1142-6723, Plückthun, Andreas; https://orcid.org/0000-0003-4191-5306, Trkola, Alexandra; https://orcid.org/0000-0003-1013-876X
المصدر: Friedrich, Nikolas; Stiegeler, Emanuel; Glögl, Matthias; Lemmin, Thomas; Hansen, Simon; Kadelka, Claus; Wu, Yufan; Ernst, Patrick; Maliqi, Liridona; Foulkes, Caio; Morin, Mylène; Eroglu, Mustafa; Liechti, Thomas; Ivan, Branislav; Reinberg, Thomas; Schaefer, Jonas V; Karakus, Umut; Ursprung, Stephan; Mann, Axel; Rusert, Peter; Kouyos, Roger D; Robinson, John A; Günthard, Huldrych F; Plückthun, Andreas; Trkola, Alexandra (2021). Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nature Communications, 12:6705.
مصطلحات الفهرس: Department of Biochemistry, Clinic for Infectious Diseases, Institute of Medical Virology, 570 Life sciences; biology, 610 Medicine & health, Journal Article, PeerReviewed, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion
URL:
https://www.zora.uzh.ch/id/eprint/210334/ https://www.zora.uzh.ch/id/eprint/210334
10.1038/s41467-021-27075-0 -
16Academic Journal
المصدر: ISSN: 1092-2172 ; Microbiology and molecular biology reviews, vol. 76, no. 4 (2012) p. 707-720.
مصطلحات موضوعية: info:eu-repo/classification/ddc/540, info:eu-repo/classification/ddc/616
Relation: info:eu-repo/semantics/altIdentifier/pmid/23204363; https://archive-ouverte.unige.ch/unige:24373; unige:24373
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17Academic Journal
المؤلفون: Marchant, Jan, Cowper, Ben, Liu, Yan, Lai, Livia, Pinzan, Camila, Marq, Jean Baptiste, Friedrich, Nikolas, Sawmynaden, Kovilen, Liew, Lloyd, Chai, Wengang, Childs, Robert A., Saouros, Savvas, Simpson, Peter, Roque Barreira, Maria Cristina, Feizi, Ten, Soldati-Favre, Dominique, Matthews, Stephen
المصدر: Journal of Biological Chemistry ; volume 287, issue 20, page 16720-16733 ; ISSN 0021-9258
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18Academic Journal
المصدر: ISSN: 0020-7519 ; International Journal for Parasitology, vol. 40, no. 10 (2010) p. 1145-1154.
مصطلحات موضوعية: info:eu-repo/classification/ddc/616, Animals, Apicomplexa/physiology, Host-Parasite Interactions, Ligands, Polysaccharides/metabolism, Sialic Acids/metabolism, Vertebrates/parasitology
Relation: info:eu-repo/semantics/altIdentifier/pmid/20430033; https://archive-ouverte.unige.ch/unige:16160; unige:16160
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19Academic Journal
المؤلفون: Sheiner, Lilach, Santos, Joana M., Klages Jemelin, Natacha, Parussini, Fabiola, Jemmely, Noelle, Friedrich, Nikolas, Ward, Gary E., Soldati-Favre, Dominique
المصدر: ISSN: 1365-2958 ; Molecular microbiology, vol. 77, no. 4 (2010) p. 912-929.
مصطلحات موضوعية: info:eu-repo/classification/ddc/616
Relation: info:eu-repo/semantics/altIdentifier/pmid/20545864; https://archive-ouverte.unige.ch/unige:12352; unige:12352
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20Academic Journal
المؤلفون: Friedrich, Nikolas, Santos, Joana M., Liu, Yan, Palma, Angelina S., Leon, Ester, Saouros, Savvas, Kiso, Makoto, Blackman, Michael J., Matthews, Stephen, Feizi, Ten, Soldati-Favre, Dominique
المصدر: Journal of Biological Chemistry ; volume 285, issue 3, page 2064-2076 ; ISSN 0021-9258