المؤلفون: Freeman, Alasdair D. J., Déclais, Anne-Cécile, Wilson, Timothy J., Lilley, David M. J.

المصدر: Freeman , A D J , Déclais , A-C , Wilson , T J & Lilley , D M J 2023 , ' Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1 ' , Nucleic Acids Research , vol. 51 , no. 11 , gkad416 , pp. 5743–5754 . https://doi.org/10.1093/nar/gkad416

مصطلحات موضوعية: DNA junctions, GIY-YIG nucleases, general acid-base catalysis, metal ion catalysis, /dk/atira/pure/subjectarea/asjc/1300/1311, name=Genetics

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/6c60c6c0-c0d1-435d-a05f-2968449741f7
https://doi.org/10.1093/nar/gkad416
https://discovery.dundee.ac.uk/ws/files/104071600/gkad416.pdf
http://www.scopus.com/inward/record.url?scp=85163858972&partnerID=8YFLogxK

المؤلفون: Freeman, Alasdair D. J.

Thesis Advisors: Hay, Ronald Thomas

مصطلحات موضوعية: QH465.F8, Radiogenetics

الاتاحة: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.750307

المؤلفون: Song, Junfang, Freeman, Alasdair D. J., Knebel, Axel, Gartner, Anton, Lilley, David M. J.

المصدر: Song , J , Freeman , A D J , Knebel , A , Gartner , A & Lilley , D M J 2020 , ' Human ANKLE1 is a nuclease specific for branched DNA ' , Journal of Molecular Biology , vol. 432 , no. 21 , pp. 5825-5834 . https://doi.org/10.1016/j.jmb.2020.08.022

مصطلحات موضوعية: chromosome segregation, helical junction resolution, ultrafine DNA bridges, LEM-3, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1315, name=Structural Biology

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/ebd2457a-bcd7-4ca0-a95d-82d3a74c2f85

الاتاحة: https://discovery.dundee.ac.uk/en/publications/ebd2457a-bcd7-4ca0-a95d-82d3a74c2f85
https://doi.org/10.1016/j.jmb.2020.08.022
https://discovery.dundee.ac.uk/ws/files/57049430/1_s2.0_S0022283620305167_main.pdf
http://www.scopus.com/inward/record.url?scp=85090923834&partnerID=8YFLogxK

المؤلفون: Liu, Yijin, Freeman, Alasdair D. J., Déclais, Anne-Cécile, Lilley, David M. J.

المصدر: Liu , Y , Freeman , A D J , Déclais , A-C & Lilley , D M J 2018 , ' A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1 ' , Nucleic Acids Research , vol. 46 , no. 20 , pp. 11089-11098 . https://doi.org/10.1093/nar/gky863

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/2034e3b4-8be7-4e0f-b870-4e553d98d119

الاتاحة: https://discovery.dundee.ac.uk/en/publications/2034e3b4-8be7-4e0f-b870-4e553d98d119
https://doi.org/10.1093/nar/gky863
https://discovery.dundee.ac.uk/ws/files/28681561/gky863.pdf

المؤلفون: Freeman, Alasdair D J, Déclais, Anne-Cécile, Wilson, Timothy J, Lilley, David M J

المصدر: Nucleic Acids Research; 6/23/2023, Vol. 51 Issue 11, p5743-5754, 12p

المؤلفون: Freeman, Alasdair D J, Stevens, Michael, Declais, Anne Cecile, Leahy, Adam, Mackay, Katherine, El Mkami, Hassane, Lilley, David M. J., Norman, David G.

المصدر: Freeman , A D J , Stevens , M , Declais , A C , Leahy , A , Mackay , K , El Mkami , H , Lilley , D M J & Norman , D G 2016 , ' Analysis of the intrinsically disordered N-terminus of the DNA junction-resolving enzyme T7 endonuclease I : identification of structure formed upon DNA binding ' , Biochemistry , vol. 55 , no. 30 , pp. 4166-4172 . https://doi.org/10.1021/acs.biochem.6b00242

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/analysis-of-the-intrinsically-disordered-nterminus-of-the-dna-junctionresolving-enzyme-t7-endonuclease-i(55d34ffa-6250-42bb-b5d8-a70b3c2a2330).html
https://doi.org/10.1021/acs.biochem.6b00242
https://research-repository.st-andrews.ac.uk/bitstream/10023/9323/1/Mkami_2016_BioChem_Analysis_CCBY.pdf
http://pubs.acs.org/doi/suppl/10.1021/acs.biochem.6b00242

المؤلفون: Liu, Yijin, Freeman, Alasdair D J, Déclais, Anne Cécile, Wilson, Timothy J., Gartner, Anton, Lilley, David M J

المصدر: Liu , Y , Freeman , A D J , Déclais , A C , Wilson , T J , Gartner , A & Lilley , D M J 2015 , ' Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA ' , Cell Reports , vol. 13 , no. 11 , pp. 2565-2575 . https://doi.org/10.1016/j.celrep.2015.11.042

مصطلحات موضوعية: DNA recombination, DNA repair, DNA-protein interactions, Holliday junction, X-ray crystallography, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/fc8a83dc-27f2-410e-af70-c1f68c1583a1
https://doi.org/10.1016/j.celrep.2015.11.042
https://discovery.dundee.ac.uk/ws/files/10491666/1_s2.0_S2211124715013571_main.pdf
http://www.scopus.com/inward/record.url?scp=84952877095&partnerID=8YFLogxK

المؤلفون: Freeman, Alasdair D. J., Liu, Yijin, Déclais, Anne-Cécile, Gartner, Anton, Lilley, David M. J.

المصدر: Freeman , A D J , Liu , Y , Déclais , A-C , Gartner , A & Lilley , D M J 2014 , ' GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes ' , Journal of Molecular Biology , vol. 426 , no. 24 , pp. 3946-3959 . https://doi.org/10.1016/j.jmb.2014.10.008

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/a24f85f4-41fb-4ed3-878f-4bbc583391c2

الاتاحة: https://discovery.dundee.ac.uk/en/publications/a24f85f4-41fb-4ed3-878f-4bbc583391c2
https://doi.org/10.1016/j.jmb.2014.10.008
https://discovery.dundee.ac.uk/ws/files/6623163/1_s2.0_S0022283614005336_main.pdf

المؤلفون: Wang, Jia, Fessl, Tomáš, Schroeder, Kersten T., Ouellet, Jonathan, Liu, Yijin, Freeman, Alasdair D. J., Lilley, David M. J.

المصدر: Wang , J , Fessl , T , Schroeder , K T , Ouellet , J , Liu , Y , Freeman , A D J & Lilley , D M J 2012 , ' Single-molecule observation of the induction of k-turn RNA structure on binding L7Ae protein ' , Biophysical Journal , vol. 103 , no. 12 , pp. 2541-2548 . https://doi.org/10.1016/j.bpj.2012.11.006

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1300/1304, name=Biophysics

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/2f204920-8335-4370-85a7-750a483e2725

الاتاحة: https://discovery.dundee.ac.uk/en/publications/2f204920-8335-4370-85a7-750a483e2725
https://doi.org/10.1016/j.bpj.2012.11.006
https://discovery.dundee.ac.uk/ws/files/32774961/1_s2.0_S0006349512012271_main.pdf
http://www.scopus.com/inward/record.url?scp=84871324763&partnerID=8YFLogxK

المؤلفون: Zhou, Ruobo, Yang, Olivia, Déclais, Anne-Cécile, Jin, Hyeonseok, Gwon, Gwang Hyeon, Freeman, Alasdair D. J., Cho, Yunje, Lilley, David M. J., Ha, Taekjip

المصدر: Nature Chemical Biology ; volume 15, issue 3, page 269-275 ; ISSN 1552-4450 1552-4469

الاتاحة: http://dx.doi.org/10.1038/s41589-018-0209-y
http://www.nature.com/articles/s41589-018-0209-y
http://www.nature.com/articles/s41589-018-0209-y.pdf

المؤلفون: Freeman, Alasdair D. J., Déclais, Anne-Cécile, Lilley, David M. J.

المصدر: Freeman , A D J , Déclais , A-C & Lilley , D M J 2013 , ' The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions ' , Journal of Molecular Biology , vol. 425 , no. 2 , pp. 395-410 . https://doi.org/10.1016/j.jmb.2012.11.029

مصطلحات موضوعية: BACTERIOPHAGE T7, ESCHERICHIA-COLI, RESOLVING ENZYME CCE1, STRUCTURAL RECOGNITION, REPLICATION FORKS, HOMOLOGOUS RECOMBINATION, GENETIC-RECOMBINATION, HOLLIDAY JUNCTION, SULFOLOBUS-SOLFATARICUS, SACCHAROMYCES-CEREVISIAE

Relation: https://discovery.dundee.ac.uk/en/publications/08a27dc2-04db-41a1-ab3d-1409ef545cdc

الاتاحة: https://discovery.dundee.ac.uk/en/publications/08a27dc2-04db-41a1-ab3d-1409ef545cdc
https://doi.org/10.1016/j.jmb.2012.11.029

المؤلفون: Freeman, Alasdair D. J., Ward, Richard, El Mkami, Hassane, Lilley, David M. J., Norman, David G.

المصدر: Freeman , A D J , Ward , R , El Mkami , H , Lilley , D M J & Norman , D G 2011 , ' Analysis of Conformational Changes in the DNA Junction-Resolving Enzyme T7 Endonuclease I on Binding a Four-Way Junction Using EPR ' , Biochemistry , vol. 50 , no. 46 , pp. 9963-9972 . https://doi.org/10.1021/bi2011898

مصطلحات موضوعية: ACTIVE-SITE, SPIN-LABELS, RECOMBINATION, SPECTROSCOPY, RNA, BACTERIOPHAGE-T7, RECOGNITION, CONVERSION, MECHANISM, PACKAGE

Relation: https://discovery.dundee.ac.uk/en/publications/d4e7ac30-dd53-4735-a30e-3eb6879d479c

الاتاحة: https://discovery.dundee.ac.uk/en/publications/d4e7ac30-dd53-4735-a30e-3eb6879d479c
https://doi.org/10.1021/bi2011898

المؤلفون: Freeman, Alasdair D J

المساهمون: Hay, Ronald Thomas

مصطلحات موضوعية: QH465.F8, Radiogenetics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______901::7c31645dc9b5dba5be6fbf62c358fb3a
https://hdl.handle.net/10023/13906

المؤلفون: Freeman, Alasdair D. J., Stevens, Michael, Declais, Anne-Cecile, Leahy, Adam, Mackay, Katherine, El Mkami, Hassane, Lilley, David M. J., Norman, David G.

المصدر: Biochemistry; 8/2/2016, Vol. 55 Issue 30, p4166-4172, 7p

المؤلفون: Freeman, Alasdair D J

المساهمون: Hay, Ronald Thomas

مصطلحات موضوعية: QH465.F8, Radiogenetics

جغرافية الموضوع: 190 p.

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10023/13906

الاتاحة: http://hdl.handle.net/10023/13906

المؤلفون: McKinney, Sean A.¹, Freeman, Alasdair D. J.², Lilley, David M. J.², Ha, Taekjip¹ tjha@uiuc.edu

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 4/19/2005, Vol. 102 Issue 16, p5715-5720. 6p.

مصطلحات موضوعية: *DNA, *GENETIC recombination, *GENETICS, *NUCLEIC acids, *BIOMOLECULES, *DEOXYRIBOSE

المؤلفون: Déclais, Anne-Cécile, Fogg, Jonathan M., Freeman, Alasdair D. J., Coste, Franck, Hadden, Jonathan M., Phillips, Simon E. V., Lilley, David M. J.

المصدر: EMBO Journal; 3/15/2003, Vol. 22 Issue 6, p1398-1409, 12p

مصطلحات موضوعية: ENZYMES, ENDONUCLEASES, DNA, NUCLEOTIDE sequence, DNA-ligand interactions, NUCLEIC acids