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1
المؤلفون: Weiguang Zhao, Raymond Unwalla, Frederick J. Bex, Richard J. Murrills, John A. Robinson, Nippa Alon, Usha Varadarajan, Paul J. Yaworsky, Adam M. Gilbert, Valerie E. Coleburn, Virginia Gironda, Diane B. Hauze, Matthew Kirisits, Michael C. Sharp, Paula Green, Yao-Bin Liu, Yogendra P. Kharode, Girija Krishnamurthy, Matthew Gregory Bursavich, Bheem M. Bhat, Michael Cain, Sabrina Lombardi, Jeanne J. Matteo, Sally Selim, Ho-Sun Lam
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:366-370
مصطلحات موضوعية: Recombinant Fusion Proteins, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Wnt3 Protein, Glycogen Synthase Kinase 3, Mice, In vivo, Cell Line, Tumor, Wnt3A Protein, Drug Discovery, Animals, Humans, Molecular Biology, GSK3B, beta Catenin, Bone Development, Glycogen Synthase Kinase 3 beta, Chemistry, Skull, Organic Chemistry, Imidazoles, Wnt signaling pathway, Transfection, Hit to lead, In vitro, Cell biology, Mice, Inbred C57BL, Wnt Proteins, Pyrimidines, Catenin, Intercellular Signaling Peptides and Proteins, Molecular Medicine, Signal transduction, Signal Transduction
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2
المؤلفون: Diane B. Hauze, Michael C. Sharp, Bheem M. Bhat, Paula Green, Colleen Milligan, Daniel M. Green, Jennifer Pirrello, Peter V.N. Bodine, Ronald L. Magolda, Adam M. Gilbert, Matthew D. Vera, Yogendra P. Kharode, Valerie E. Coleburn, Luciana De Araujo Felix, Mattew G. Bursavich, Nipa Alon, Jeanne J. Matteo, Jay Wrobel, Frederick J. Bex, Jeffrey C. Pelletier, Susan Lockhead, Joseph T. Lundquist, Richard J. Murrills, Ray Unwalla, Paul J. Yaworsky, Sally Selim, John F. Mehlmann, Ho-Sun Lam
المصدر: Journal of Medicinal Chemistry. 52:6962-6965
مصطلحات موضوعية: Models, Molecular, Agonist, medicine.drug_class, Pharmacology, Glycogen Synthase Kinase 3, Mice, Piperidines, Pharmacokinetics, Osteogenesis, Oral administration, Catalytic Domain, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, beta Catenin, Glycogen Synthase Kinase 3 beta, Chemistry, Wnt signaling pathway, Small molecule, In vitro, Rats, Wnt Proteins, Pyrimidines, Biochemistry, Catenin, Ovariectomized rat, Molecular Medicine, Signal Transduction
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3
المؤلفون: Ramesh A. Bhat, Rachelle L. Samuel, Jennifer L. Andrews, Peter V.N. Bodine, Frederick J. Bex, Valerie E. Coleburn, Richard J. Murrills, Bheem M. Bhat
المصدر: Journal of Cellular Biochemistry. 106:887-895
مصطلحات موضوعية: MAPK/ERK pathway, Epidermal Growth Factor, Adenylate kinase, Parathyroid hormone, Cell Biology, Biology, Response Elements, Biochemistry, Adenosine Monophosphate, Cell biology, Parathyroid Hormone, Cell Line, Tumor, Cyclic AMP, Cancer research, Humans, Calcium, Cyclic AMP Response Element, Signal transduction, Protein kinase A, Molecular Biology, Protein kinase B, Protein Kinase C, Protein kinase C, Signal Transduction
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4
المؤلفون: Anthony Anisowicz, Catherine McCauley, Valerie E. Coleburn, Art Morales, Frederick J. Bex, Paul J. Yaworsky, Bheem M. Bhat, James R. Graham, Eric Fortier, Wei Liu, Kristina Allen, Ramesh A. Bhat, Michael Cain, Ho-Sun Lam
المصدر: Gene. 391:103-112
مصطلحات موضوعية: Models, Molecular, Frizzled, animal structures, Mutation, Missense, Biology, medicine.disease_cause, Autoantigens, Structure-Activity Relationship, Protein structure, Cell Line, Tumor, Genetics, medicine, Humans, Missense mutation, Luciferases, beta Catenin, Cell Nucleus, Mutation, Point mutation, Wnt signaling pathway, LRP5, General Medicine, Protein Structure, Tertiary, Cell biology, Wnt Proteins, Protein Transport, Ribonucleoproteins, Mutation testing, Intercellular Signaling Peptides and Proteins, TCF Transcription Factors, Signal Transduction
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5
المؤلفون: Linda Sauter, Robert R. Recker, Mark L. Johnson, Barry S. Komm, Moitreyee Chatterjee-Kishore, Frederick J. Bex, Yogendra P. Kharode, Paul J. Yaworsky, Weiguang Zhao, Philip Babij, Mohammed P. Akhter, Andrew A. Hill, Eugene L. Brown, Christine Li, Diane M. Cullen, John A. Robinson
المصدر: Journal of Biological Chemistry. 281:31720-31728
مصطلحات موضوعية: Transcription, Genetic, Transgene, Connexin, Mice, Transgenic, Wnt1 Protein, Biology, Biochemistry, Bone and Bones, Glycogen Synthase Kinase 3, Mice, Cyclin D1, GSK-3, Animals, Molecular Biology, GSK3B, beta Catenin, DNA Primers, Glycogen Synthase Kinase 3 beta, Osteoblasts, Wnt signaling pathway, LRP5, Cell Biology, Cell biology, Phenotype, Cancer research, RNA, Stress, Mechanical, Signal transduction, Signal Transduction
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6
المؤلفون: Peter V.N. Bodine, Yogendra P. Kharode, Barry S. Komm, Laura M. Seestaller-Wehr, Frederick J. Bex
المصدر: Journal of Cellular Physiology. 210:352-357
مصطلحات موضوعية: Aging, medicine.medical_specialty, Bone density, Anabolism, Physiology, Clinical Biochemistry, Parathyroid hormone, Bone and Bones, Mice, Calcification, Physiologic, Bone Density, Osteogenesis, Secreted frizzled-related protein 1, Teriparatide, Internal medicine, medicine, Animals, Femur, Quantitative computed tomography, Mice, Knockout, Bone mineral, Bone Development, medicine.diagnostic_test, Chemistry, Membrane Proteins, Cell Biology, Peptide Fragments, Wnt Proteins, Disease Models, Animal, Endocrinology, Parathyroid Hormone, Intercellular Signaling Peptides and Proteins, Female, Signal Transduction, Hormone, medicine.drug
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7
المؤلفون: Peter V.N. Bodine, Ramesh A. Bhat, Frederick J. Bex, John A. Robinson, Julia Billiard, Barry S. Komm
المصدر: Clinical Reviews in Bone and Mineral Metabolism. 4:73-96
مصطلحات موضوعية: medicine.medical_specialty, biology, Endocrinology, Diabetes and Metabolism, Wnt signaling pathway, LRP6, ROR2, LRP5, Osteoblast, Receptor tyrosine kinase, Endocrinology, medicine.anatomical_structure, Osteoclast, Osteocyte, Internal medicine, medicine, biology.protein, Orthopedics and Sports Medicine
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8
المؤلفون: Kees Kenneth L, Valerie E. Coleburn, Frederick J. Bex, Horace Fletcher, Bheem M. Bhat, Jeanne J. Matteo, Richard J. Murrills, Charles William Mann, Diane B. Hauze
المصدر: Letters in Drug Design & Discovery. 2:201-204
مصطلحات موضوعية: Biochemistry, biology, Chemistry, Drug Discovery, Aspartic acid, biology.protein, Pharmaceutical Science, Molecular Medicine, Vitronectin, In vitro
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9
المؤلفون: Jeanne J. Matteo, Valerie E. Coleburn, Bheem M. Bhat, Rachelle L. Samuel, Richard J. Murrills, Yogendra P. Kharode, Jennifer L. Andrews, Frederick J. Bex
المصدر: Bone. 35:1263-1272
مصطلحات موضوعية: Histology, Physiology, G protein, Endocrinology, Diabetes and Metabolism, Biology, Rats, Sprague-Dawley, Bone Density, In vivo, Cell Line, Tumor, Cyclic AMP, Animals, Humans, Calcium Signaling, Receptor, chemistry.chemical_classification, Dose-Response Relationship, Drug, Biological activity, Peptide Fragments, In vitro, Cyclic peptide, Rats, Biochemistry, chemistry, Parathyroid Hormone, Receptors, Parathyroid Hormone, cAMP-dependent pathway, Female, Cyclic AMP Response Element, hormones, hormone substitutes, and hormone antagonists, Protein Binding
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10
المؤلفون: Barry S. Komm, Gadi Turgeman, Peter V.N. Bodine, Luis E. Borella, Shuanhu Zhou, Yogendra P. Kharode, Yoram Zilberman, Dan Gazit, Frederick J. Bex, Ioannis Moutsatsos, Pam Kelly
المصدر: Journal of Cellular Biochemistry. 86:461-474
مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, Anabolism, medicine.drug_class, Ovariectomy, Osteoporosis, Bone Morphogenetic Protein 2, Apoptosis, Bone morphogenetic protein, Biochemistry, Bone and Bones, Mesoderm, Mice, Osteogenesis, Transforming Growth Factor beta, Internal medicine, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, Mice, Inbred BALB C, Mice, Inbred ICR, Dose-Response Relationship, Drug, business.industry, Stem Cells, Cartilage, Mesenchymal stem cell, Cell Biology, Alkaline Phosphatase, medicine.disease, Recombinant Proteins, Enzyme Activation, Osteopenia, Bone Diseases, Metabolic, Endocrinology, medicine.anatomical_structure, Estrogen, Bone Morphogenetic Proteins, Female, business
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11
المؤلفون: Laura L. Carter, Barry S. Komm, Dharmesh Patel, Yanong D Wang, Yogendra P. Kharode, Shoichi Fukayama, Max Follettie, Jeanne J. Matteo, Jason Jussif, Vikki Spaulding, Yao-Bin Liu, Frank Boschelli, Giovan Lane, Yuchen Bai, Frederick J. Bex, Veronica Diesl, X. Jian Li, Richard J. Murrills, Colleen Milligan, Diane H. Boschelli, Peter V.N. Bodine, John C McKew, Jennifer M. Golas, Susan Lockhead, Jane Owens
المصدر: The Journal of pharmacology and experimental therapeutics. 340(3)
مصطلحات موضوعية: medicine.medical_specialty, Cellular differentiation, Molecular Sequence Data, Osteoclasts, Calvaria, Bone resorption, Mice, In vivo, Osteogenesis, Internal medicine, medicine, Animals, Humans, Amino Acid Sequence, Proto-Oncogene Proteins c-abl, Protein Kinase Inhibitors, Pharmacology, Osteoblasts, Cell growth, Chemistry, Gene Expression Profiling, Osteoblast, Cell Differentiation, medicine.disease, Osteopenia, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, src-Family Kinases, Ovariectomized rat, Molecular Medicine
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12
المؤلفون: Arthur A Santilli, Frederick J Bex
المصدر: Current Opinion on Therapeutic Patents. 3:23-49
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, business.industry, Osteoporosis, medicine, medicine.disease, Intensive care medicine, business
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13
المؤلفون: Jeanne J. Matteo, Veronique Damagnez, Valerie E. Coleburn, Kristina Allen, Wei Chen, Ramesh A. Bhat, Frederick J. Bex, Richard J. Murrills, Peter V.N. Bodine, Bheem M. Bhat
المصدر: Journal of cellular biochemistry. 108(5)
مصطلحات موضوعية: musculoskeletal diseases, Mutant, Receptors, Cell Surface, Biology, medicine.disease_cause, Biochemistry, Bone and Bones, Cell Line, medicine, Extracellular, Humans, Protein Interaction Domains and Motifs, Receptor, Molecular Biology, LDL-Receptor Related Proteins, Mutation, Binding Sites, Ligand binding assay, Wnt signaling pathway, Wild type, Cell Biology, Transfection, Molecular biology, Low Density Lipoprotein Receptor-Related Protein-5, Amino Acid Substitution, Receptors, LDL, Low Density Lipoprotein Receptor-Related Protein-6, Intercellular Signaling Peptides and Proteins, Biological Assay, Molecular Chaperones, Protein Binding
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14
المؤلفون: Jeanne J. Matteo, Richard J. Murrills, Matthew C. Mendel, Siyuan Tan, Casey C. Case, Bheem M. Bhat, Philip D. Gregory, Brian D Schlag, Kathleen H. Young, Pei-Qi Liu, Katherine Howes, Frederick J. Bex, Rachelle L. Samuel, Andreas Reik, Ragan de la Rosa
المصدر: Journal of biomolecular screening. 10(4)
مصطلحات موضوعية: 0301 basic medicine, Molecular Sequence Data, Repressor, Biology, Protein Engineering, 01 natural sciences, Biochemistry, Analytical Chemistry, Cell Line, 03 medical and health sciences, Humans, Amino Acid Sequence, RNA, Messenger, Transcription factor, DNA Primers, Receptor, Parathyroid Hormone, Type 1, Zinc finger, Regulation of gene expression, Base Sequence, Activator (genetics), Reverse Transcriptase Polymerase Chain Reaction, HEK 293 cells, Zinc Fingers, Molecular biology, Isogenic human disease models, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Gene Expression Regulation, Molecular Medicine, Target protein, Biotechnology, Transcription Factors
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15
المؤلفون: Andre-Jean Lambert, Weiguang Zhao, Yogendra P. Kharode, Peter V.N. Bodine, Tripti Gaur, Jane B. Lian, Barry S. Komm, Gary S. Stein, Mary Beth Goad, Frederick J. Bex
المصدر: Molecular endocrinology (Baltimore, Md.). 18(5)
مصطلحات موضوعية: Male, medicine.medical_specialty, Apoptosis, Biology, Bone remodeling, Mice, Endocrinology, Secreted frizzled-related protein 1, Bone Density, Osteogenesis, Internal medicine, medicine, Animals, Tissue Distribution, RNA, Messenger, Molecular Biology, Mice, Knockout, Osteoblasts, Wnt signaling pathway, Intracellular Signaling Peptides and Proteins, Proteins, Osteoblast, General Medicine, Wnt Proteins, Apposition, medicine.anatomical_structure, Osteocyte, Intercellular Signaling Peptides and Proteins, Cortical bone, Female, Protein Binding, Signal Transduction
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16
المؤلفون: Weiguang Zhao, Bheem M. Bhat, John A. Robinson, Mary L. Bouxsein, Peter V.N. Bodine, Yogendra P. Kharode, Robert A. Moran, Paul J. Yaworsky, Philip Babij, James Marzolf, Frederick J. Bex, Padmalatha S. Reddy, Clayton Small
المصدر: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 18(6)
مصطلحات موضوعية: medicine.medical_specialty, Aging, Bone density, Bone disease, Endocrinology, Diabetes and Metabolism, Mutant, Osteoclasts, Mice, Transgenic, Biology, Polymerase Chain Reaction, Bone and Bones, Mice, Osteoclast, Bone Density, Internal medicine, medicine, Image Processing, Computer-Assisted, Animals, Humans, Orthopedics and Sports Medicine, LDL-Receptor Related Proteins, DNA Primers, Bone mineral, Bone Development, Base Sequence, LRP5, Osteoblast, medicine.disease, Alkaline Phosphatase, Rats, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, Low Density Lipoprotein Receptor-Related Protein-5, Receptors, LDL, Mutagenesis, Site-Directed, Alkaline phosphatase, Tomography, X-Ray Computed
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17
المؤلفون: Frederick J. Bex, AnnaMarie Cannistraci, Wah-Tung Hum, Stephen Caltabiano, David Gralnick, Gwilym J. Attwell, Lori J. Budman
المصدر: Biochemical pharmacology. 58(10)
مصطلحات موضوعية: Protein Conformation, Sialoglycoproteins, Integrin, Biochemistry, CD49c, Collagen receptor, Cell Line, stomatognathic system, Cell Adhesion, Tumor Cells, Cultured, Humans, Receptors, Vitronectin, Osteopontin, Cell adhesion, Pharmacology, biology, Molecular biology, Recombinant Proteins, Extracellular Matrix, Integrin alpha M, Cell culture, biology.protein, Integrin, beta 6, HT29 Cells, Oligopeptides
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18Academic Journal
المؤلفون: Jeffrey C. Pelletier, Joseph T. Lundquist, Adam M. Gilbert, Nipa Alon, Frederick J. Bex, Bheem M. Bhat, Mattew G. Bursavich, Valerie E. Coleburn, Luciana A. Felix, Daniel M. Green, Paula Green, Diane B. Hauze, Yogendra P. Kharode, Ho-Sun Lam, Susan R. Lockhead, Ronald L. Magolda, Jeanne J. Matteo, John F. Mehlmann, Colleen Milligan, Richard J. Murrills
المصدر: Journal of Medicinal Chemistry; Nov2009, Vol. 52 Issue 22, p6962-6965, 4p
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19Academic Journal
المؤلفون: Pei-Qi Liu, Siyuan Tan, Matthew C. Mendel, Richard J. Murrills, Bheem M. Bhat, Brian Schlag, Rachelle Samuel, Jeanne J. Matteo, Ragan de la Rosa, Katherine Howes, Andreas Reik, Casey C. Case, Frederick J. Bex, Kathleen Young, Philip D. Gregory
المصدر: Journal of Biomolecular Screening; Jun2005, Vol. 10 Issue 4, p304-313, 10p
مصطلحات موضوعية: CELLS, GENE expression, ZINC, PROTEINS
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20
المؤلفون: Frederick J. Bex, Alan Corbin
المصدر: Journal of Andrology. 2:152-161
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Hypophysectomy, medicine.drug_class, Urology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, medicine.disease, In vitro, Basal (phylogenetics), Endocrinology, Atrophy, Reproductive Medicine, In vivo, Internal medicine, Dihydrotestosterone, medicine, Testosterone, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e46e58a305c301c3e72554998866b76d
https://doi.org/10.1002/j .1939-4640.1981.tb00610.x