المؤلفون: Karel H van der Pol, Jan Koenderink, Jeroen J M W van den Heuvel, Petra van den Broek, Janny Peters, Imke D W van Bunningen, Jeanne Pertijs, Frans G M Russel, Jim Koldenhof, Wim J Morshuis, Joris van Drongelen, Tom J J Schirris, Andries van der Meer, Gerard A Rongen

المصدر: PLoS ONE, Vol 19, Iss 6, p e0305906 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fd27e0ee1021449984bd8991649ed5a0

المؤلفون: Laurens F M Verscheijden, Carlijn H C Litjens, Jan B Koenderink, Ron H J Mathijssen, Marcel M Verbeek, Saskia N de Wildt, Frans G M Russel

المصدر: PLoS Computational Biology, Vol 17, Iss 3, p e1008786 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/453e7f115c204fa085ec5f77bb94a806

المؤلفون: Laurens F M Verscheijden, Jan B Koenderink, Saskia N de Wildt, Frans G M Russel

المصدر: PLoS Computational Biology, Vol 15, Iss 6, p e1007117 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/2821067b0bc043ab9c57c0e99109d14f

المؤلفون: Jan A J G van den Brand, Henricus A M Mutsaers, Arjan D van Zuilen, Peter J Blankestijn, Petra H van den Broek, Frans G M Russel, Rosalinde Masereeuw, Jack F M Wetzels

المصدر: PLoS ONE, Vol 11, Iss 12, p e0168117 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5199014?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6044e7fb22b148d4a9a0889241bac67f

المؤلفون: Christy C Bridges, Lucy Joshee, Jeroen J M W van den Heuvel, Frans G M Russel, Rudolfs K Zalups

المصدر: PLoS ONE, Vol 8, Iss 9, p e73559 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3764057?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d801008678d34fcdb84553c84f9824d5

المؤلفون: Rachel P L van Swelm, Coby M M Laarakkers, Ellen C van der Kuur, Eva Morava-Kozicz, Ron A Wevers, Kevin D Augustijn, Daan J Touw, Maro H Sandel, Rosalinde Masereeuw, Frans G M Russel

المصدر: PLoS ONE, Vol 7, Iss 11, p e49524 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3498140?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e72eb2e6d83c4354b2efc7eb581a84fb

المؤلفون: Henricus A M Mutsaers, Lambertus P van den Heuvel, Lauke H J Ringens, Anita C A Dankers, Frans G M Russel, Jack F M Wetzels, Joost G Hoenderop, Rosalinde Masereeuw

المصدر: PLoS ONE, Vol 6, Iss 4, p e18438 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3070735?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/ec1fc460e32c4920aea7f4dea2f781cb

المؤلفون: Harold Tjalsma, Coby M M Laarakkers, Rachel P L van Swelm, Milan Theurl, Igor Theurl, Erwin H Kemna, Yuri E M van der Burgt, Hanka Venselaar, Bas E Dutilh, Frans G M Russel, Günter Weiss, Rosalinde Masereeuw, Robert E Fleming, Dorine W Swinkels

المصدر: PLoS ONE, Vol 6, Iss 3, p e16762 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3050808?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3ed65de1b8834ba2bf4efc8df56a6788

المؤلفون: Alwin Scharstuhl, Henricus A M Mutsaers, Sebastiaan W C Pennings, Frans G M Russel, Frank A D T G Wagener

المصدر: PLoS ONE, Vol 4, Iss 8, p e6688 (2009)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2725322?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/aa811b64867d4106ba1b0599c82d7e6a

المؤلفون: Carlijn H. C. Litjens, Laurens F. M. Verscheijden, Elin M. Svensson, Petra H. H. van den Broek, Hedwig van Hove, Jan B. Koenderink, Frans G. M. Russel, Rob E. Aarnoutse, Lindsey H. M. te Brake

المصدر: Antibiotics; Volume 12; Issue 4; Pages: 702

مصطلحات موضوعية: PBPK, linezolid, tuberculous meningitis

وصف الملف: application/pdf

Relation: Pharmacokinetics and Pharmacodynamics of Drugs; https://dx.doi.org/10.3390/antibiotics12040702

الاتاحة: https://doi.org/10.3390/antibiotics12040702

المؤلفون: Tim Somers, Sailay Siddiqi, Wim J. Morshuis, Frans G. M. Russel, Tom J. J. Schirris

المصدر: Journal of Cardiovascular Development and Disease, Vol 10, Iss 417, p 417 (2023)

مصطلحات موضوعية: statins, beneficial and adverse effects, cardiomyocytes, metabolism, clinical translation, Diseases of the circulatory (Cardiovascular) system, RC666-701

Relation: https://www.mdpi.com/2308-3425/10/10/417; https://doaj.org/toc/2308-3425; https://doaj.org/article/0369d11886e34b0fbea49a9a76ae6a9e

الاتاحة: https://doi.org/10.3390/jcdd10100417
https://doaj.org/article/0369d11886e34b0fbea49a9a76ae6a9e

المؤلفون: Tim Somers, Neeltje A. E. Allard, Sailay Siddiqi, Margit C. M. Janssen, Maria T. E. Hopman, Wim J. Morshuis, Frans G. M. Russel, Silvie Timmers, Tom J. J. Schirris

المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-023-36741-w; https://doaj.org/toc/2045-2322; https://doaj.org/article/07377571bfc6436db3445afffa3a5dad

الاتاحة: https://doi.org/10.1038/s41598-023-36741-w
https://doaj.org/article/07377571bfc6436db3445afffa3a5dad

المؤلفون: Charlotte A. Hoogstraten, Jan A. M. Smeitink, Frans G. M. Russel, Tom J. J. Schirris

المصدر: Frontiers in Toxicology, Vol 4 (2022)

مصطلحات موضوعية: acute kidney injury, drug-induced toxicity, cellular metabolic activity, cell viability, metabolic toxicity, Toxicology. Poisons, RA1190-1270

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.842396/full; https://doaj.org/toc/2673-3080; https://doaj.org/article/ccdecf3852684e1fbe255f1219a61346

الاتاحة: https://doi.org/10.3389/ftox.2022.842396
https://doaj.org/article/ccdecf3852684e1fbe255f1219a61346

المؤلفون: Eva J. Streekstra, Márton Kiss, Jeroen van denHeuvel, Johan Nicolaï, Petra van denBroek, Sanne M. B. I. Botden, Martijn W. J. Stommel, Lara vanRijssel, Anna‐Lena Ungell, Evita van deSteeg, Frans G. M. Russel, Saskia N. deWildt

المصدر: Clinical and Translational Science, Vol 15, Iss 10, Pp 2392-2402 (2022)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

Relation: https://doi.org/10.1111/cts.13368; https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062; https://doaj.org/article/19dc0c00bdde4a0c98ee0dc9ad49aa34

الاتاحة: https://doi.org/10.1111/cts.13368
https://doaj.org/article/19dc0c00bdde4a0c98ee0dc9ad49aa34

المؤلفون: Charlotte A. Hoogstraten, Maaike M. E. Jacobs, Guido de Boer, Melissa A. E. van de Wal, Werner J. H. Koopman, Jan A. M. Smeitink, Frans G. M. Russel, Tom J. J. Schirris

المصدر: Archives of Toxicology, 97, 1927-1941
Archives of Toxicology, 97, 7, pp. 1927-1941

مصطلحات موضوعية: All institutes and research themes of the Radboud University Medical Center, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Health, Toxicology and Mutagenesis, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], General Medicine, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624b90cdb0fa6ad59940574f54a19058
https://hdl.handle.net/2066/293800

المؤلفون: Jochem Louisse, Luca Dellafiora, Jeroen J. M. W. van den Heuvel, Deborah Rijkers, Liz Leenders, Jean-Lou C. M. Dorne, Ans Punt, Frans G. M. Russel, Jan B. Koenderink

المصدر: Archives of Toxicology, 97, 3, pp. 685-696
Archives of Toxicology 97 (2023) 3
Archives of Toxicology, 97(3), 685-696
Archives of Toxicology, 97, 685-696

مصطلحات موضوعية: Team Organic Contaminants, Health, Toxicology and Mutagenesis, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Team Toxicology, General Medicine, Transporter, Toxicology, OAT4, All institutes and research themes of the Radboud University Medical Center, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], In vitro, PFASs, Renal reabsorption, URAT1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a27e391e6bed55ba30277471e5341f
https://hdl.handle.net/2066/291310

المؤلفون: Nori J. L. Smeets, Carlijn H. C. Litjens, Jeroen J. M. W. van den Heuvel, Hedwig van Hove, Petra van den Broek, Frans G. M. Russel, Jan B. Koenderink, Saskia N. de Wildt

المصدر: Pharmaceutics; Volume 12; Issue 10; Pages: 935

مصطلحات موضوعية: enalapril, enalaprilat, drug transporters, proximal tubule cell

وصف الملف: application/pdf

Relation: Pharmacokinetics and Pharmacodynamics; https://dx.doi.org/10.3390/pharmaceutics12100935

الاتاحة: https://doi.org/10.3390/pharmaceutics12100935

المؤلفون: Eva J. Streekstra, Frans G. M. Russel, Saskia N. de Wildt, Evita van de Steeg

المصدر: Drug Discovery Today: Technologies, 39, 31-48
Drug Discovery Today: Technologies, 39, pp. 31-48

مصطلحات موضوعية: Adult, Proteomics, business.industry, Quantitative proteomics, Membrane Transport Proteins, Transporter, Computational biology, Pediatric drug, Limited access, Drug metabolizing enzymes, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Pharmaceutical Preparations, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Drug Discovery, Humans, Molecular Medicine, Medicine, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], Child, business, Chromatography, Liquid, Pediatric population

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a440982ce2a061ca26d4ad31fd2ab7fc
https://doi.org/10.1016/j.ddtec.2021.06.008

المؤلفون: Apoorva Kotian, Nico Kist, Rene M. H. Wijnen, Saskia N. de Wildt, Johan Nicolaï, Anna-Lena Ungell, Paul Cutler, Márton Kiss, Frans G. M. Russel, Richard Mbasu, M. G. Mooij, Karin Barnouin

المساهمون: Pediatric Surgery

المصدر: Drug Metabolism and Disposition, 49, 12, pp. 1038-1046
Drug Metabolism and Disposition, 49(12), 1038-1046. American Society for Pharmacology and Experimental Therapeutics
Drug Metabolism and Disposition, 49, 1038-1046

مصطلحات موضوعية: Adult, Metabolic Clearance Rate, Biological Transport, Active, Pharmaceutical Science, Ileum, Pharmacology, Peptide Transporter 1, digestive system, Jejunum, All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, Tandem Mass Spectrometry, Multidrug Resistance Protein 1, Intestine, Small, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Humans, Glucuronosyltransferase, Child, Enzyme Assays, Organic cation transport proteins, biology, Multidrug resistance-associated protein 2, Peptide transporter 1, Age Factors, Membrane Transport Proteins, Multidrug Resistance-Associated Protein 2, Neoplasm Proteins, Gene Ontology, medicine.anatomical_structure, Monocarboxylate transporter 1, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Inactivation, Metabolic, biology.protein, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], Drug metabolism, Chromatography, Liquid

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6345e070847ec4b94376735da97969
https://pure.eur.nl/en/publications/1403454e-7805-47b0-8fbc-c2871a463613

المؤلفون: Celine Bolwerk, Cecile Magis-Escurra, Wouter Hoefsloot, Laurens F. M. Verscheijden, Arjan van Laarhoven, David M. Burger, Jakko van Ingen, Jan B. Koenderink, Frans G. M. Russel, Reinout van Crevel, Rob E. Aarnoutse, Martin J. Boeree, Rovina Ruslami, Petra H.H. van den Broek, Carlijn H. C. Litjens, Lindsey H.M. te Brake, Elin M. Svensson, Jeroen J. M. W. van den Heuvel, Saskia Kuipers, Rick Greupink

المصدر: Journal of Clinical Pharmacology and Journal of New Drugs, 62, 3, pp. 385-396
Journal of Clinical Pharmacology and Journal of New Drugs, 62, 385-396

مصطلحات موضوعية: Adult, Drug, drug-drug interactions, Tuberculosis, media_common.quotation_subject, Moxifloxacin, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Pharmacokinetic modeling, Antitubercular Agents, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Pharmacology and Toxicology, Pharmacology, Multiple dose, Models, Biological, physiologically based pharmacokinetics, Pharmaceutical Sciences, Pharmacokinetics, In vivo, medicine, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Glucuronosyltransferase, Child, media_common, business.industry, modeling, Farmakologi och toxikologi, Farmaceutiska vetenskaper, bacterial infections and mycoses, medicine.disease, Multidrug Resistance-Associated Protein 2, HEK293 Cells, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], tuberculosis, Area Under Curve, Drug Therapy, Combination, Rifampin, moxifloxacin, business, Rifampicin, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e627cee41f24ef6bdaceab6a4f0d8b
https://doi.org/10.1002/jcph.1972