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1
المؤلفون: Douglas J. Kelly, Natalie J. Welsh, Mark A. A. Neil, Yuriy Alexandrov, Edward J. Murray, Sunil Kumar, Edward W. Tate, Paul M. W. French, Ian Munro, Remigiusz A. Serwa, Vania M.M. Braga, Anca Margineanu, Christopher Dunsby, Emmanuelle Thinon, James McGinty, Mesayamas Kongsema, Frank Stuhmeier, Clifford Talbot, Sean C. Warren, Eric Lam, Jessica McCormack, Dominic Alibhai
المصدر: Analytical Methods. 7:4071-4089
مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Fluorophore, General Chemical Engineering, Systems biology, General Engineering, Nanotechnology, Fluorescence, Analytical Chemistry, chemistry.chemical_compound, Förster resonance energy transfer, chemistry, High-content screening, Microscopy, Plate reader
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2
المؤلفون: Yuriy Alexandrov, Edward J. Murray, Clifford Talbot, James McGinty, Sunil Kumar, Dominic Alibhai, Emmanuelle Thinon, Paul M. W. French, Remigiusz A. Serwa, Vincenzo da Paola, Mark A. A. Neil, Edwin Garcia, Ian Munro, Frank Stuhmeier, Lucien West, Douglas J. Kelly, Edward W. Tate, Christopher Dunsby, Sean C. Warren, Frederik Görlitz
المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC), Wellcome Trust, Engineering & Physical Science Research Council (E, Medical Research Council (MRC)
المصدر: Journal of Visualized Experiments : JoVE
مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Computer science, General Chemical Engineering, PROTEIN, 02 engineering and technology, Biosensing Techniques, RESONANCE ENERGY-TRANSFER, gag Gene Products, Human Immunodeficiency Virus, fluorescence microscopy, 0302 clinical medicine, open source, BIOSENSOR, Chlorocebus aethiops, Fluorescence microscope, Fluorescence Resonance Energy Transfer, HCA, 030212 general & internal medicine, LIVING CELLS, General Neuroscience, Optical Imaging, 021001 nanoscience & nanotechnology, TIME, Multidisciplinary Sciences, High-content screening, COS Cells, Science & Technology - Other Topics, 0210 nano-technology, Biological system, STANDARDS, FLIM, Biophysics, automated microscopy, General Biochemistry, Genetics and Molecular Biology, drug discovery, 03 medical and health sciences, Open source data, Animals, Humans, Issue 119, Science & Technology, General Immunology and Microbiology, Open source, Förster resonance energy transfer, Microscopy, Fluorescence, Time course, NADH, FRET, Biosensor, Software
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3
المؤلفون: Edward W. Tate, Yuriy Alexandrov, Edward J. Murray, Frank Stuhmeier, Paul M. W. French, Christopher Dunsby, Emmanuelle Thinon, Mark A. A. Neil, Sunil Kumar, Anca Margineau, Sean C. Warren, Douglas J. Kelly, Dominic Alibhai, Remigiusz A. Serwa
المصدر: Journal of Biophotonics
مصطلحات موضوعية: Resonant inductive coupling, Fluorescence-lifetime imaging microscopy, protein-protein interactions, General Physics and Astronomy, 01 natural sciences, gag Gene Products, Human Immunodeficiency Virus, chemistry.chemical_compound, Automation, BIOSENSOR, Fluorescence Resonance Energy Transfer, General Materials Science, HCA, LIVING CELLS, SPATIAL-RESOLUTION, 0303 health sciences, fluorescence lifetime imaging microscopy (FLIM), Chemistry, General Engineering, MICROSCOPY, Fluorescence, NETWORKS, 3. Good health, Molecular Imaging, HIV-1 Gag, Physical Sciences, Life Sciences & Biomedicine, Plate reader, Biochemistry & Molecular Biology, FLIM, Fluorophore, Biophysics, CONTRAST, Nanotechnology, Biochemical Research Methods, General Biochemistry, Genetics and Molecular Biology, 010309 optics, 03 medical and health sciences, Full Article, 0103 physical sciences, Humans, Protein Structure, Quaternary, 030304 developmental biology, Science & Technology, IDENTIFICATION, Optics, General Chemistry, Editor's Choice, Förster resonance energy transfer, FRET, Molecular imaging, Protein Multimerization, Biosensor, HeLa Cells
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4
المؤلفون: Eunsun Lee, Peter Cornelius, Ruduan Wang, Kim F. McClure, Frank Stuhmeier, Janice A. Brown, James G. Boyd, Wen Lin, Wendy Werner
المصدر: SLAS Discovery. 14:360-370
مصطلحات موضوعية: Tryptamine, Agonist, Serotonin, medicine.drug_class, High-throughput screening, Fluorescence Polarization, Biochemistry, Analytical Chemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Receptor, Serotonin, 5-HT2C, medicine, Animals, Humans, Receptor, Fluorescent Dyes, Staining and Labeling, Ligand binding assay, Reproducibility of Results, Reference Standards, Ligand (biochemistry), 5-HT2C receptor, Kinetics, chemistry, Drug Design, NIH 3T3 Cells, Biophysics, Molecular Medicine, Biological Assay, Fluorescence anisotropy, Biotechnology
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5
المؤلفون: Robert M. Clegg, Frank Stuhmeier, Stephan Diekmann, Alexander Hillisch
المصدر: Journal of Molecular Biology. 302:1081-1100
مصطلحات موضوعية: Quantitative Biology::Biomolecules, biology, chemistry.chemical_compound, Crystallography, Förster resonance energy transfer, chemistry, Structural Biology, Adenine nucleotide, Bulge, Helix, biology.protein, Protein–DNA interaction, Molecular Biology, DNA, Fluorescence anisotropy, Catabolite activator protein
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6
المؤلفون: Frank Stuhmeier, Alastair I.H. Murchie, Jonathan B. Welch, David M.J. Lilley, Robert M. Clegg
المصدر: Biochemistry. 36:13530-13538
مصطلحات موضوعية: Energy transfer, Astrophysics::Cosmology and Extragalactic Astrophysics, Sodium Chloride, Biochemistry, Ion, chemistry.chemical_compound, Bulge, Adenine nucleotide, Condensed Matter::Superconductivity, Nucleotide, Astrophysics::Galaxy Astrophysics, Fluorescent Dyes, chemistry.chemical_classification, Base Composition, Quantitative Biology::Biomolecules, Base Sequence, Rhodamines, Chemistry, DNA, Quantitative Biology::Genomics, Fluorescence, Solutions, Crystallography, Spectrometry, Fluorescence, Förster resonance energy transfer, Energy Transfer, Nucleic Acid Conformation, Fluorescein, Atomic physics
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7
المؤلفون: Eric Lam, Douglas J. Kelly, Paul M. W. French, Matilda Katan, Sunil Kumar, Mark A. A. Neil, Sean C. Warren, Christopher Dunsby, Edward J. Murray, Dominic Alibhai, Frank Stuhmeier, Anca Margineanu
المصدر: Scopus-Elsevier
مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Materials science, business.industry, Energy transfer, Image intensifier, Multiwell plate, law.invention, Optics, Förster resonance energy transfer, law, High-content screening, Microscopy, Fluorescence microscope, business
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المؤلفون: Anne Phelan, Iain Kilty, Russell Andrew Lewthwaite, Darren Baldock, David S. Millan, Mathias John Paul, Frank Stuhmeier, David G. Brown, Andrew Pannifer, Samantha Hughes, Mark Anthony O'reilly
المصدر: Bioorganicmedicinal chemistry letters. 21(21)
مصطلحات موضوعية: High concentration, Models, Molecular, Virtual screening, Cell Membrane Permeability, Fragment (computer graphics), Kinase, Chemistry, Organic Chemistry, Clinical Biochemistry, Cell, Pharmaceutical Science, Metabolic stability, Ligand (biochemistry), Biochemistry, Structure-Activity Relationship, medicine.anatomical_structure, Drug Stability, Drug Discovery, medicine, Molecular Medicine, Transferase, Molecular Biology, Protein Kinase Inhibitors, Phosphoinositide-3 Kinase Inhibitors
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9
المؤلفون: James McGinty, Yuriy Alexandrov, Frank Stuhmeier, Edward J. Murray, Dominic Alibhai, Mark A. A. Neil, Clifford Talbot, Douglas J. Kelly, Paul M. W. French, Christopher Dunsby, Sean C. Warren, Ian Munro, Sunil Kumar
المصدر: SPIE Proceedings.
مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Förster resonance energy transfer, Chemistry, viruses, High-content screening, Microscopy, Biophysics, 96 well plate, Multiwell plate, Wide field, Protein–protein interaction
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10
المؤلفون: Sean C. Warren, Francois Lacombe, Gordon Stamp, Anca Margineanu, Clifford Talbot, Ian Munro, Frank Stuhmeier, Christopher Dunsby, Bertrand Viellerobe, Yuriy Alexandrov, Alessandro Sardini, Harriet B. Taylor, Matilda Katan, Dominic Alibhai, Edward J. Murray, J. McGinty, Sunil Kumar, Gordon T. Kennedy, Paul M. W. French, Margaret J. Dallman, Romain F. Laine, Douglas J. Kelly, Christopher Kimberly, Mark A. A. Neil, Eric Lam, Daniel W. Stuckey, Daniel S. Elson
المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC), Engineering & Physical Science Research Council (EPSRC), Cancer Research UK
المصدر: Chemphyschem
مصطلحات موضوعية: In situ, Fluorescence-lifetime imaging microscopy, Drug Evaluation, Preclinical, Physics, Atomic, Molecular & Chemical, RESONANCE ENERGY-TRANSFER, 01 natural sciences, gag Gene Products, Human Immunodeficiency Virus, FREQUENCY-DOMAIN, Fluorescence Resonance Energy Transfer, CYAN FLUORESCENT PROTEIN, LIVING CELLS, 0306 Physical Chemistry (incl. Structural), 0303 health sciences, Chemistry, Drug discovery, Chemistry, Physical, Physics, OPTICAL PROJECTION TOMOGRAPHY, VIRUS TYPE-1 GAG, CORRELATION SPECTROSCOPY, LIVE CELLS, Atomic and Molecular Physics, and Optics, fluorescence lifetime imaging, High-content screening, Physical Sciences, 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics, Protein Binding, Confocal, High-throughput screening, Green Fluorescent Proteins, Nanotechnology, high-throughput screening, Article, drug discovery, Cell Line, 010309 optics, 03 medical and health sciences, 0103 physical sciences, Endomicroscopy, Humans, LIFETIME IMAGING MICROSCOPY, 0307 Theoretical and Computational Chemistry, Physical and Theoretical Chemistry, 030304 developmental biology, Fluorescent Dyes, Science & Technology, Chemical Physics, Rhodamines, Proteins, SIGNALING EVENTS, Förster resonance energy transfer, Microscopy, Fluorescence, FRET
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11
المؤلفون: William H. Martin, Joachim Fries, Dirk Winkler, Robin W. Spencer, R. Eryl Sharp, Neil Benson, Helen Boyd, Karsten Henco, Travis J. Mathewson, Nuzrul Haque, Jeremy R. Everett, Timm Jessen, Frank Stuhmeier, Philip Gribbon, Mark S. Wallace
المصدر: Journal of biomolecular screening. 10(6)
مصطلحات موضوعية: 0301 basic medicine, Time Factors, Screening test, Computer science, High-throughput screening, Chemistry, Pharmaceutical, Drug Storage, Drug Evaluation, Preclinical, Nanotechnology, 01 natural sciences, Biochemistry, Mass Spectrometry, Analytical Chemistry, Specimen Handling, 03 medical and health sciences, Automation, Inhibitory Concentration 50, Constant (computer programming), Drug Stability, Combinatorial Chemistry Techniques, Sensitivity (control systems), Process engineering, business.industry, Process (computing), Temperature, Chemical space, 0104 chemical sciences, Molecular Weight, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Models, Chemical, Pharmaceutical Preparations, Solubility, Molecular Medicine, business, Biotechnology, Chromatography, Liquid
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12
المؤلفون: Frank Stuhmeier, Robert M. Clegg, David M.J. Lilley
المصدر: Biochemistry. 36(44)
مصطلحات موضوعية: Models, Molecular, Base Composition, Oligonucleotide, Temperature, DNA, Chromophore, Sodium Chloride, Nucleic Acid Denaturation, Biochemistry, Fluorescence, Solutions, chemistry.chemical_compound, Crystallography, Förster resonance energy transfer, Spectrometry, Fluorescence, chemistry, Adenine nucleotide, Nucleic Acid Conformation, Denaturation (biochemistry), Anisotropy