المؤلفون: Marzia Bianchi, Luigia Rossi, Francesca Pierigè, Pietro De Angeli, Mattia Paolo Aliano, Claudia Carducci, Emanuele Di Carlo, Tiziana Pascucci, Francesca Nardecchia, Vincenzo Leuzzi, Mauro Magnani

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 26-40 (2022)

مصطلحات موضوعية: metabolic engineering, guanidinoacetate methyltransferase (GAMT), GAMT deficiency, methionine adenosyl transferase, creatine deficit, RBC loading, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122000237; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/072330cee6434a5fa288ce93803cac8c

المؤلفون: Alessandro Bregalda, Claudia Carducci, Maria Teresa Viscomi, Francesca Pierigè, Sara Biagiotti, Michele Menotta, Federica Biancucci, Tiziana Pascucci, Vincenzo Leuzzi, Mauro Magnani, Luigia Rossi

المصدر: Neurobiology of Disease, Vol 180, Iss , Pp 106093- (2023)

مصطلحات موضوعية: Myelin basic protein, Phenylketonuria, MicroRNA, Microarray, Mouse maturation, Cerebral plasticity, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996123001079; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/ea2f98d722914820afd10ddc5e353fa0

المؤلفون: Luigia Rossi, Francesca Pierigè, Marco Agostini, Noemi Bigini, Veronica Termopoli, Yingting Cai, Fang Zheng, Chang-Guo Zhan, Donald W. Landry, Mauro Magnani

المصدر: Frontiers in Physiology, Vol 11 (2020)

مصطلحات موضوعية: cocaine use disorder, cocaine esterase, red blood cells as drug delivery system, cocaine degradation, RBP 8000 stability, E196-301 stability, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2020.573492/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/11175c615f6b4940bff621ea6f7e36c3

المؤلفون: Gioena Pampalone, Davide Chiasserini, Francesca Pierigè, Emidio Camaioni, Pier Luigi Orvietani, Alessandro Bregalda, Michele Menotta, Ilaria Bellezza, Luigia Rossi, Barbara Cellini, Mauro Magnani

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 14, p 7931 (2024)

مصطلحات موضوعية: ornithine aminotransferase, gyrate atrophy, pyridoxal phosphate, enzyme administration, drug delivery, erythrocytes, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/14/7931; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/d56a3cffce1d4a09a0e62018fa912937

الاتاحة: https://doi.org/10.3390/ijms25147931
https://doaj.org/article/d56a3cffce1d4a09a0e62018fa912937

المؤلفون: Alessandro Bregalda, Claudia Carducci, Tiziana Pascucci, Patrizia Ambrogini, Stefano Sartini, Francesca Pierigè, Emanuele di Carlo, Elena Fiori, Donald Ielpo, Marica Pagliarini, Vincenzo Leuzzi, Mauro Magnani, Luigia Rossi

المساهمون: Bregalda, Alessandro, Carducci, Claudia, Pascucci, Tiziana, Ambrogini, Patrizia, Sartini, Stefano, Pierigè, Francesca, DI CARLO, Emanuele, Fiori, Elena, Ielpo, Donald, Pagliarini, Marica, Leuzzi, Vincenzo, Magnani, Mauro, Rossi, Luigia

مصطلحات موضوعية: LNAA, Motor Skill, Myelin Integrity, Neurotransmitter, Phenylketonuria

Relation: journal:MOLECULAR GENETICS AND METABOLISM; https://hdl.handle.net/11573/1716488; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85199254008

الاتاحة: https://hdl.handle.net/11573/1716488
https://doi.org/10.1016/j.ymgme.2024.108543

المؤلفون: Luigia Rossi, Francesca Nardecchia, Francesca Pierigè, Rossella Ventura, Claudia Carducci, Vincenzo Leuzzi, Mauro Magnani, Simona Cabib, Tiziana Pascucci

المصدر: Genes; Volume 12; Issue 8; Pages: 1201

مصطلحات موضوعية: GAMT deficiency, genetic mouse model, behavioral phenotyping, developmental delay

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes12081201

الاتاحة: https://doi.org/10.3390/genes12081201

المؤلفون: Luigia Rossi, Francesca Pierigè, Mattia Paolo Aliano, Mauro Magnani

المساهمون: Rossi, Luigia, Pierige', Francesca, Aliano, MATTIA PAOLO, Magnani, Mauro

مصطلحات موضوعية: Engineered RBCs have now reached clinical development with some products already in phase III. Leading companies in phase III include EryDel SpA and Erytech Pharma, others have received FDA and/or EMA clearance for patient recruitment (Rubius Therapeutics and St George’s, University of London with Orphan Technologies). Orphan drug designation has been obtained by the FDA and EMA for several drug product, several regulatory paths to approval have been defned with the main regulatory agencies

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000520899600002; volume:34; issue:3; firstpage:265; lastpage:272; numberofpages:8; journal:BIODRUGS; info:eu-repo/grantAgreement/EC/H2020/667946; http://hdl.handle.net/11576/2676754; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211199/pdf/40259_2020_Article_415.pdf

الاتاحة: http://hdl.handle.net/11576/2676754
https://doi.org/10.1007/s40259-020-00415-0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211199/pdf/40259_2020_Article_415.pdf

المؤلفون: Mauro Magnani, Francesca Pierigè, Alessandro Bregalda, Luigia Rossi

مصطلحات موضوعية: Pharmaceutical Science

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/97501

الاتاحة: https://www.openaccessrepository.it/record/97501
https://doi.org/10.1080/17425247.2020.1822320

المؤلفون: Bregalda, Alessandro, Carducci, Claudia, Viscomi, Maria Teresa, Pierigè, Francesca, Biagiotti, Sara, Menotta, Michele, Biancucci, Federica, Pascucci, Tiziana, Leuzzi, Vincenzo, Magnani, Mauro, Rossi, Luigia, Alessandro Bregalda, Claudia Carducci, Maria Teresa Viscomi (ORCID:0000-0002-9096-4967), Francesca Pierigè, Sara Biagiotti, Michele Menotta, Federica Biancucci, Tiziana Pascucci, Vincenzo Leuzzi, Mauro Magnani, Luigia Rossi

مصطلحات الفهرس: myelin, Settore BIO/17 - ISTOLOGIA, info:eu-repo/semantics/article

URL: https://hdl.handle.net/10807/232887
issue:180
firstpage:N/A
lastpage:N/A
numberofpages:1
issueyear:2023
journal:NEUROBIOLOGY OF DISEASE

المؤلفون: Marzia Bianchi, Luigia Rossi, Francesca Pierigè, Sara Biagiotti, Alessandro Bregalda, Filippo Tasini, Mauro Magnani

المساهمون: Bianchi, Marzia, Rossi, Luigia, Pierigè, Francesca, Biagiotti, Sara, Bregalda, Alessandro, Tasini, Filippo, Magnani, Mauro

مصطلحات موضوعية: Drug-loaded RBC, RBC-derived extracellular vesicle, cancer therapy, enzyme replacement therapy, guanidinoacetate methyltransferase deficiency, metabolic disease, therapeutic protein delivery, toxic molecule removal

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001003072600001; firstpage:1; lastpage:15; numberofpages:15; journal:EXPERT OPINION ON DRUG DELIVERY; https://hdl.handle.net/11576/2716751; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85161553478

الاتاحة: https://hdl.handle.net/11576/2716751
https://doi.org/10.1080/17425247.2023.2219890

المؤلفون: Tiziana Pascucci, Luigia Rossi, Marco Colamartino, Claudia Gabucci, Claudia Carducci, Alessandro Valzania, Valeria Sasso, Noemi Bigini, Francesca Pierigè, Maria Teresa Viscomi, Rossella Ventura, Simona Cabi, Mauro Magnani, Stefano Puglisi-Allegra, Vincenzo Leuzzi

المساهمون: Pascucci, Tiziana, Rossi, Luigia, Colamartino, Marco, Gabucci, Claudia, Carducci, Claudia, Valzania, Alessandro, Sasso, Valeria, Bigini, Noemi, Pierige', Francesca, Teresa Viscomi, Maria, Ventura, Rossella, Cabi, Simona, Magnani, Mauro, Puglisi-Allegra, Stefano, Leuzzi, Vincenzo

مصطلحات موضوعية: PKU mouse model Phenylalanine ammonia lyase Erythrocytes as drug delivery system Enzyme replacement therapy Cognition and PKU Behavior and PKU

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000434101300005; volume:124; firstpage:39; lastpage:49; numberofpages:11; journal:MOLECULAR GENETICS AND METABOLISM; http://hdl.handle.net/11576/2660649; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85045301430

الاتاحة: http://hdl.handle.net/11576/2660649
https://doi.org/10.1016/j.ymgme.2018.03.009

المؤلفون: Mauro Magnani, Francesca Pierigè, Luigia Rossi, Mattia Paolo Aliano

المصدر: Biodrugs

مصطلحات موضوعية: Drug, Asparaginase, Erythrocytes, media_common.quotation_subject, others have received FDA and/or EMA clearance for patient recruitment (Rubius Therapeutics and St George’s, Leading Article, Engineered RBCs have now reached clinical development with some products already in phase III. Leading companies in phase III include EryDel SpA and Erytech Pharma, others have received FDA and/or EMA clearance for patient recruitment (Rubius Therapeutics and St George’s, University of London with Orphan Technologies). Orphan drug designation has been obtained by the FDA and EMA for several drug products, several regulatory paths to approval have been defned with the main regulatory agencies, Bioinformatics, Dexamethasone, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacotherapy, Pancreatic cancer, medicine, Humans, Pharmacology (medical), Thymidine phosphorylase, Cell Engineering, Phenylalanine Ammonia-Lyase, media_common, 030203 arthritis & rheumatology, Pharmacology, Clinical Trials as Topic, Drug Carriers, Thymidine Phosphorylase, business.industry, General Medicine, medicine.disease, 3. Good health, Clinical trial, Tolerability, chemistry, 030220 oncology & carcinogenesis, Ataxia-telangiectasia, University of London with Orphan Technologies). Orphan drug designation has been obtained by the FDA and EMA for several drug products, business, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8a1c417180fd5e31d9b5341429c39a
https://hdl.handle.net/11576/2676754

المؤلفون: David Machover, Luigia Rossi, Jocelyne Hamelin, Christophe Desterke, Emma Goldschmidt, Bernadette Chadefaux-Vekemans, Pascal Bonnarme, Pierre Briozzo, David Kope
, cný, Francesca Pierigè, Mauro Magnani, Rosella Mollicone, Farhad Haghighi-Rad, Yann Gaston-Mathé, Julien Dairou, Claude Boucheix, and Raphaël Saffroy

المساهمون: Machover, David, Rossi, Luigia, Hamelin, Jocelyne, Desterke, Christophe, Goldschmidt, Emma, Chadefaux-Vekemans, Bernadette, Bonnarme, Pascal, Briozzo, Pierre, Kope
, David, Cný, Pierigè, Francesca, Magnani, Mauro, Mollicone, Rosella, Haghighi-Rad, Farhad, Gaston-Mathé, Yann, Dairou, Julien, Boucheix, Claude, Raphaël Saffroy, And

Relation: journal:THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS; https://hdl.handle.net/11576/2734171

الاتاحة: https://hdl.handle.net/11576/2734171
https://doi.org/10.1124/jpet.119.256537

المؤلفون: Luigia Rossi, Francesca Pierigè, Ferdinando Mannello, Giorgio Brandi, Michael Smietana, Giulia Amagliani, Mauro Magnani, Giuditta Fiorella Schiavano, Carolina Zara, Daniela Ligi, Alessandra Fraternale

المصدر: International Journal of Antimicrobial Agents. 56:106148

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), medicine.drug_class, Cysteamine, medicine.medical_treatment, 030106 microbiology, Microbial Sensitivity Tests, Antimycobacterial, Antimycobacterial compounds, Glutathione, Mycobacterium avium, Pro-glutathione molecules, Redox homeostasis, Redox, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, biology, Chemistry, Macrophages, Intracellular parasite, General Medicine, Prodrug, biology.organism_classification, Acetylcysteine, Anti-Bacterial Agents, Cell biology, Oxidative Stress, Infectious Diseases, Cytokine, Cytokines, Oxidation-Reduction, Bacteria, Mycobacterium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e36a420b223c7016c6ab82d6e34e022
https://doi.org/10.1016/j.ijantimicag.2020.106148

المؤلفون: David, Machover, Luigia, Rossi, Jocelyne, Hamelin, Christophe, Desterke, Emma, Goldschmidt, Bernadette, Chadefaux-Vekemans, Pascal, Bonnarme, Pierre, Briozzo, David, Kopečný, Francesca, Pierigè, Mauro, Magnani, Rosella, Mollicone, Farhad, Haghighi-Rad, Yann, Gaston-Mathé, Julien, Dairou, Claude, Boucheix, Raphaël, Saffroy

المصدر: The Journal of pharmacology and experimental therapeutics. 369(3)

مصطلحات موضوعية: Adult, Carbon-Sulfur Lyases, Mice, Bioreactors, Erythrocytes, Methionine, Cell Line, Tumor, Animals, Brevibacterium, Humans, Capsules, Recombinant Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4c0a8e2428c264f8f7539324f48c3ea2
https://pubmed.ncbi.nlm.nih.gov/30940696

المؤلفون: E. Goldschmidt, Raphaël Saffroy, Julien Dairou, David Kopečný, Pascal Bonnarme, Pierre Briozzo, Luigia Rossi, Bernadette Chadefaux-Vekemans, Mauro Magnani, Francesca Pierigè, Rosella Mollicone, Jocelyne Hamelin, Claude Boucheix, Yann Gaston-Mathé, Farhad Haghighi-Rad, David Machover, Christophe Desterke

المساهمون: Hôpital Paul Brousse, Modèles de Cellules Souches Malignes et Thérapeutiques, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Sud - Paris 11 (UP11), Université Paris Saclay (COmUE), Università degli Studi di Urbino 'Carlo Bo', Physiopathologie et traitement des maladies du foie, Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5), Génie et Microbiologie des Procédés Alimentaires (GMPA), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Institut Jean-Pierre Bourgin (IJPB), Palacky University Olomouc, Interactions cellules souches-niches : physiologie, tumeurs et réparation tissulaire, Université Paris-Sud - Paris 11 (UP11)-Service de Santé des Armées-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), YGM Consult sas, Partenaires INRAE, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut du Cancer et d'Immunogenetique (ICIG), Hospital Paul-Brousse, Villejuif, France

المصدر: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2019, 369 (3), pp.489-502. ⟨10.1124/jpet.119.256537⟩

مصطلحات موضوعية: 0301 basic medicine, ENZYME, [SDV]Life Sciences [q-bio], Serum albumin, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, [SDV.IDA]Life Sciences [q-bio]/Food engineering, medicine, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, [SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering, PYRIDOXAL 5'-PHOSPHATE, GENE CLONING, Cytotoxicity, COMBINATION, Escherichia coli, IN-VIVO, Pharmacology, chemistry.chemical_classification, Methionine, biology, IDENTIFICATION, Chemistry, METHYLATION, EFFICACY, Enzyme assay, 3. Good health, PSEUDOMONAS-PUTIDA, 030104 developmental biology, Enzyme, Biochemistry, Cell culture, Cancer cell, biology.protein, Molecular Medicine, 5-FLUOROURACIL, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e81788dc0da9dd0c68e94688f57707
https://hal.inrae.fr/hal-02619075

المؤلفون: Francesca Pierigè, Paul A. Fitzpatrick, Tiziana Pascucci, Luigia Rossi, Barbara Canonico, Sean M. Bell, Vincenzo Leuzzi, Claudia Carducci, Mauro Magnani, Claudia Gabucci

المصدر: Journal of Controlled Release. 194:37-44

مصطلحات موضوعية: Erythrocytes, Phenylalanine hydroxylase, erythrocytes as delivery system, enzyme replacement therapy, Phenylalanine, Biological Availability, Pharmaceutical Science, Mice, Inbred Strains, Phenylalanine ammonia-lyase, Biology, Pharmacology, law.invention, Mice, Drug Delivery Systems, In vivo, law, Phenylketonurias, Animals, Humans, Phenylalanine Ammonia-Lyase, chemistry.chemical_classification, Drug Carriers, Carrier erythrocytes, Drug delivery, PKU mouse model, Enzyme replacement therapy, Dose-Response Relationship, Drug, PKU mouse model, Therapeutic effect, Carrier erythrocytes, Enzyme replacement therapy, Recombinant Proteins, Enzyme, chemistry, Biochemistry, Immunoglobulin G, Drug delivery, Recombinant DNA, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a475f303db6fc447bd9682ae33680
https://doi.org/10.1016/j.jconrel.2014.08.012

المؤلفون: Luigia Rossi, Francesca Pierigè, Mauro Magnani, Noemi Bigini

مصطلحات موضوعية: 0301 basic medicine, Erythrocytes, business.industry, Biomedical Engineering, Medicine (miscellaneous), Contrast Media, Bioengineering, Nanotechnology, 02 engineering and technology, Business process reengineering, Computational biology, 021001 nanoscience & nanotechnology, Key features, 03 medical and health sciences, Erythrocyte membrane, 030104 developmental biology, Drug Delivery Systems, Targeted drug delivery, Human erythrocytes, Medicine, Animals, Humans, Prodrugs, 0210 nano-technology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22f9438e4c94b14258f2adc260864f1
https://hdl.handle.net/11576/2642094

المؤلفون: Sonja Serafini, Francesca Pierigé, Filomena Paoletti, Andrea Carnevali, ANTONELLI, ANTONELLA, SFARA, CARLA, ORLANDI, CHIARA, CASABIANCA, ANNA, FRATERNALE, ALESSANDRA, ROSSI, LUIGIA, SCHIAVANO, GIUDITTA FIORELLA, MAGNANI, MAURO

المساهمون: Sonja, Serafini, Francesca, Pierigé, Filomena, Paoletti, Antonelli, Antonella, Sfara, Carla, Orlandi, Chiara, Casabianca, Anna, Fraternale, Alessandra, Rossi, Luigia, Andrea, Carnevali, Schiavano, GIUDITTA FIORELLA, Magnani, Mauro

وصف الملف: STAMPA

Relation: ispartofbook:CNB8 8th National Biotechnology Congress; 8th NATIONAL BIOTECHNOLOGY CONGRESS, CNB8; http://hdl.handle.net/11576/2564175

الاتاحة: http://hdl.handle.net/11576/2564175

المؤلفون: Mauro Magnani, Luigia Rossi, Sonja Serafini, Francesca Pierigè

المصدر: Advanced Drug Delivery Reviews. 60:286-295

مصطلحات موضوعية: Drug, Drug Carriers, Erythrocytes, Cell Transplantation, business.industry, Macrophages, media_common.quotation_subject, Large capacity, Pharmaceutical Science, Pharmacology, Bioavailability, Drug Delivery Systems, Pharmaceutical Preparations, Pharmacokinetics, Targeted drug delivery, Drug delivery, Animals, Humans, Medicine, business, Drug carrier, Cell based, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274f7bbbccacbc18c7b9c607304166de
https://doi.org/10.1016/j.addr.2007.08.029