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1Academic Journal
المؤلفون: Pyruvate Dehydrogenase Kinase, Thomas Cadoudal, Emilie Distel, Sylvie Durant, Françoise Fouque, Jean-marc Blouin, Martine Collinet, Sylvie Bortoli, Claude Forest, Chantal Benelli
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/89/16/Diabetes_2008_Sep_57(9)_2272-2279.tar.gz
وصف الملف: application/zip
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2
المؤلفون: Isabelle Desguerre, Charles Haenggell, Françoise Fouque, Sara Seneca, Cécile Marsac, Willy Lissens, Linda De Meirleir, Gérard Ponsot, Inge Liebaers, Chantal Benelli
المساهمون: Department of Embryology and Genetics, Pediatrics
المصدر: Vrije Universiteit Brussel
مصطلحات موضوعية: Heterozygote, Base pair, Molecular Sequence Data, Pyruvate Dehydrogenase Complex, Biology, medicine.disease_cause, chemistry.chemical_compound, Exon, Genetics, medicine, Humans, E1 alpha gene, pyruvate dehydrogenase deficiency, Molecular Biology, Gene, Pyruvate Dehydrogenase Complex Deficiency Disease, Genetics (clinical), X chromosome, Repetitive Sequences, Nucleic Acid, Sequence Deletion, chemistry.chemical_classification, Mutation, Base Composition, Base Sequence, Infant, General Medicine, Exons, medicine.disease, PDHc, Pyruvate dehydrogenase deficiency, Lactic acid, Enzyme, chemistry, Female
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3The c.5242C>A BRCA1 missense variant induces exon skipping by increasing splicing repressors binding
المؤلفون: Stefania Millevoi, Laurence Gladieff, Sandra Bernat, Stéphan Vagner, Christine Toulas, Gilles Favre, Françoise Fouque, Dominique Telly
المصدر: Breast Cancer Research and Treatment. 120:391-399
مصطلحات موضوعية: Adult, Cancer Research, Heterogeneous Nuclear Ribonucleoprotein A1, RNA Splicing, Molecular Sequence Data, Genes, BRCA1, Mutation, Missense, Exonic splicing enhancer, Breast Neoplasms, Biology, 03 medical and health sciences, Exon, 0302 clinical medicine, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Humans, Protein Isoforms, Genetic Predisposition to Disease, Gene, 030304 developmental biology, Ovarian Neoplasms, Genetics, 0303 health sciences, Base Sequence, BRCA1 Protein, Reverse Transcriptase Polymerase Chain Reaction, RNA, Exons, Middle Aged, Exon skipping, Pedigree, BRCT domain, Oncology, 030220 oncology & carcinogenesis, RNA splicing, Female
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4
المؤلفون: Chantal Benelli, Claude Forest, Françoise Fouque, Thomas Cadoudal
المصدر: médecine/sciences. 24:407-414
مصطلحات موضوعية: chemistry.chemical_classification, medicine.medical_specialty, Chemistry, Adipose tissue, Fatty acid, General Medicine, medicine.disease, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, NEFA, Endocrinology, Insulin resistance, Adipocyte, Internal medicine, medicine, Glyceroneogenesis, Lipolysis, Phosphoenolpyruvate carboxykinase
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5
المؤلفون: Chantal Benelli, Françoise Fouque, Jean-Marc Blouin, Sylvie Durant, Claude Forest, Martine Collinet, Thomas Cadoudal, Emilie Distel, Sylvie Bortoli
المصدر: Diabetes
مصطلحات موضوعية: Adult, Glycerol, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Adipose Tissue, White, Subcutaneous Fat, Adipose tissue, PDK4, White adipose tissue, Biology, Protein Serine-Threonine Kinases, Gene Expression Regulation, Enzymologic, Rats, Sprague-Dawley, Rosiglitazone, Mice, Internal medicine, Internal Medicine, medicine, Glyceroneogenesis, Adipocytes, Animals, Humans, Hypoglycemic Agents, chemistry.chemical_classification, Fatty Acids, Fatty acid, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, 3T3 Cells, Middle Aged, Pyruvate dehydrogenase complex, Rats, Rats, Zucker, Up-Regulation, Endocrinology, Metabolism, chemistry, Biochemistry, Female, Thiazolidinediones, Pyruvate kinase, medicine.drug
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6
المؤلفون: Françoise Fouque, Chantal Benelli, Eric Duplus, André F. Reis, Claude Forest, Gilberto Velho
المساهمون: Physiologie cellulaire des régulations hormonale, nutritionnelles et pharmacologiques (UMR-S-530), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Neurobiologie des processus adaptatifs (NPA), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Immunologie, génétique et traitement des maladies métaboliques et du diabète (UMR_S 561), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5), This work was supported by INSERM, Université René Descartes, the Fondation pour la Recherche Médicale and the Association pour la Recherche contre le Cancer (to CF). Phenotype data and DNA banking of type 2 diabetes patients was supported by a grant from INSERM/Merck, Sharp Dhome & Chibret for research in Clinical Investigation Centers (INSERM CIC 9303 NEM). ED was recipient of a fellowship from the Ministère de l'Education Nationale et de la Recherche and a recipient of the 2000 Award from the 'Institut Danone'. AFR was supported by a post-doctoral grant from the Fondation pour la Recherche Médicale, France. Rosiglitazone (BRL 49653) was a gift from Dr. Steve Smith (Glaxo Smith Kline, Middlesex, UK)., Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Physiologie cellulaire des régulations hormonale, nutritionnelles et pharmacologiques ( UMR-S-530 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Neurobiologie des processus adaptatifs ( NPA ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Immunologie, génétique et traitement des maladies métaboliques et du diabète ( UMR_S 561 ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris Descartes - Paris 5 ( UPD5 )
المصدر: Biochimie
Biochimie, Elsevier, 2003, 85, pp.1257-1264. ⟨10.1016/j.biochi.2003.10.016⟩
Biochimie, 2003, 85, pp.1257-1264. ⟨10.1016/j.biochi.2003.10.016⟩
Biochimie, Elsevier, 2003, 85, pp.1257-1264. 〈10.1016/j.biochi.2003.10.016〉مصطلحات موضوعية: medicine.medical_specialty, Adipose tissue, Peroxisome proliferator-activated receptor, Retinoid X receptor, Biology, PPAR, Biochemistry, Gene Expression Regulation, Enzymologic, Rosiglitazone, [ SDV.NEU.SC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, chemistry.chemical_compound, Gene Frequency, Internal medicine, PCK2, Adipocyte, medicine, Glyceroneogenesis, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, RNA, Messenger, Promoter Regions, Genetic, [ SDV.BBM ] Life Sciences [q-bio]/Biochemistry, Molecular Biology, chemistry.chemical_classification, Polymorphism, Genetic, Retinoid X receptor alpha, Population-association study, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Type 2 diabetes, General Medicine, PPAR gamma, Enhancer Elements, Genetic, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Organ Specificity, Hyperglycemia, Phosphoenolpyruvate Carboxykinase (GTP), Thiazolidinediones, PEPCK-C, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), Phosphoenolpyruvate carboxykinase
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7
المؤلفون: Bénédicte Antoine, Joelle Quette, Elmus G. Beale, Wael Khazen, Claude Forest, Françoise Fouque, Chantal Benelli, Geneviève Chauvet, Joan Tordjman
المصدر: Biochimie. 85:1213-1218
مصطلحات موضوعية: Glycerol, Regulation of gene expression, Fatty Acids, Tretinoin, General Medicine, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Cytosol, Diabetes Mellitus, Type 2, chemistry, Adipocyte, Glyceroneogenesis, medicine, Animals, Phosphoenolpyruvate Carboxykinase (GTP), Thiazolidinediones, Phosphoenolpyruvate carboxykinase, Fatty acid homeostasis, Transcription factor, hormones, hormone substitutes, and hormone antagonists, medicine.drug
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8
المؤلفون: Audrey Boutron, Michelle Brivet, Chantal Benelli, Cécile Marsac, Françoise Fouque, Christiane Vequaud, Marie-Therese Zabot
المصدر: Pediatric Research. 53:793-799
مصطلحات موضوعية: Male, medicine.medical_specialty, Pyruvate Dehydrogenase Complex, Dichloroacetic acid, In Vitro Techniques, Biology, Dihydrolipoyllysine-Residue Acetyltransferase, Severity of Illness Index, chemistry.chemical_compound, Enzyme activator, Internal medicine, medicine, Humans, Pyruvate Dehydrogenase (Lipoamide), Lymphocytes, Pyruvate Dehydrogenase Complex Deficiency Disease, Cells, Cultured, Dichloroacetic Acid, Point mutation, Infant, Fibroblasts, Pyruvate dehydrogenase complex, medicine.disease, Pyruvate dehydrogenase deficiency, Enzyme Activation, Endocrinology, chemistry, Cell culture, Pediatrics, Perinatology and Child Health, Female
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9
المؤلفون: Françoise Fouque, Jean-Pierre Clot, Valérie Nivet, Claire Lugnier, Chantal Benelli, Valérie Geoffroy, Bernard Desbuquois
المصدر: European Journal of Biochemistry. 259:892-900
مصطلحات موضوعية: medicine.medical_specialty, Cilostamide, Activator (genetics), Phosphodiesterase 3, Phosphodiesterase, Biochemistry, Molecular biology, chemistry.chemical_compound, Enzyme activator, Endocrinology, chemistry, Internal medicine, medicine, EHNA, Protein kinase A, Protein kinase C, medicine.drug
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المصدر: Archives of Biochemistry and Biophysics. 387:154-162
مصطلحات موضوعية: Male, Gene isoform, medicine.medical_specialty, Phosphodiesterase Inhibitors, medicine.medical_treatment, Phosphodiesterase 3, Biophysics, Golgi Apparatus, Adipose tissue, Endosomes, Quinolones, Biology, Biochemistry, Glucagon, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, In vivo, Internal medicine, medicine, Animals, Insulin, Obesity, Cyclic GMP, Molecular Biology, Cilostamide, Phosphodiesterase, Cyclic Nucleotide Phosphodiesterases, Type 3, Hormones, Rats, Rats, Zucker, Isoenzymes, Pyridazines, Endocrinology, Liver, chemistry, 3',5'-Cyclic-AMP Phosphodiesterases, Growth Hormone, Subcellular Fractions
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11
المؤلفون: Alessandro Agostino, Cécile Marsac, C Benelli, Isabelle Desguerre, Marie O. Pequignot, Marzia Tartari, Massimo Zeviani, Carina Prip-Buus, Marc Abitbol, Dominique Marchant, Runu Dey, Françoise Fouque
المصدر: Journal of Biological Chemistry. 276:15326-15329
مصطلحات موضوعية: Male, Heterozygote, RNA Splicing, Respiratory chain, medicine.disease_cause, Biochemistry, Mitochondrial Proteins, Exon, medicine, Humans, Cytochrome c oxidase, SURF1, Base Sequence, DNA Primers, Female, Homozygote, Infant, Leigh Disease, Membrane Proteins, Proteins, Mutation, Molecular Biology, Gene, Genetics, biology, Intron, Cell Biology, Pyruvate dehydrogenase complex, Molecular biology, biology.protein
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12
المؤلفون: M. Abitbol, Cécile Marsac, J. M. Saudubray, C Rouillac, C Benelli, Yves Dumez, Françoise Fouque, G. Lindsay, Bernard Aral, Jean-Louis Dufier, Dominique Marchant
المصدر: Prenatal Diagnosis. 19:1160-1164
مصطلحات موضوعية: Genetics, Protein subunit, Haplotype, Obstetrics and Gynecology, Biology, medicine.disease, Pyruvate dehydrogenase complex, Complementary DNA, medicine, Coding region, Allele, Leigh disease, Gene, Genetics (clinical)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::58c5e22ba206815613d991d8a0777cf1
https://doi.org/10.1002/(sici)1097-0223(199912)19:12<1160::aid-pd712>3.0.co;2-2 -
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المؤلفون: Bernard Desbuquois, Chantal Benelli, Françoise Fouque, Isabelle Hainaut, Mohamed Amessou, Neirouz Soussi, Jean Girard
المصدر: Molecular and Cellular Endocrinology. 144:139-147
مصطلحات موضوعية: Matched-Pair Analysis, Protein subunit, Blotting, Western, Mitochondria, Liver, Pyruvate Dehydrogenase Complex, Mitochondrial pyruvate dehydrogenase complex, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, Mitochondria, Heart, Endocrinology, Hyperinsulinism, Gene expression, Hyperinsulinemia, medicine, Animals, Pyruvate Dehydrogenase (Lipoamide), Longitudinal Studies, Obesity, Northern blot, Molecular Biology, Reverse Transcriptase Polymerase Chain Reaction, Blotting, Northern, medicine.disease, Pyruvate dehydrogenase complex, Molecular biology, Rats, Rats, Zucker, Up-Regulation, Blot, Organ Specificity
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14
المؤلفون: Cécile Marsac, Chantal Benelli, Françoise Fouque, Bernard Aral, Mohamed Amessou, Ghania Ait-Ghezala, Nicole Créau, P. Kamoun, Catherine Maunoury
المصدر: The American Journal of Human Genetics. 61:1318-1326
مصطلحات موضوعية: Male, DNA, Complementary, DNA Mutational Analysis, Molecular Sequence Data, Muscle Proteins, Biology, medicine.disease_cause, Polymerase Chain Reaction, Protein Structure, Secondary, Protein X, Pyruvate dehydrogenase complex, Complementary DNA, Gene expression, Genetics, medicine, Humans, Genetics(clinical), Amino Acid Sequence, RNA, Messenger, Northern blot, Cloning, Molecular, Dihydrolipoyl transacetylase, Gene, In Situ Hybridization, Fluorescence, Genetics (clinical), Sequence Deletion, Mutation(s), Mutation, Sequence Homology, Amino Acid, Lactic acidosis, Chromosomes, Human, Pair 11, Infant, Newborn, Chromosome Mapping, Molecular biology, Open reading frame, “Database cloning”, Genes, Biochemistry, Organ Specificity, Acidosis, Lactic, Female, Peptides, Sequence Alignment, cDNA, Research Article
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15
المؤلفون: Isabelle Desguerre, Gérard Ponsot, Sara Seneca, Françoise Fouque, Daniel Fontan, Jean-Marie Saudubray, Cécile Marsac, L. De Meirleir, Monique Diry, C Benelli, F Poggi, Marie-Thérèse Zabot, Willy Lissens
المساهمون: Department of Embryology and Genetics, Pediatrics
المصدر: Vrije Universiteit Brussel
مصطلحات موضوعية: Male, DNA, Complementary, Adolescent, Blotting, Western, Pyruvate Dehydrogenase Complex, Biology, Gene mutation, pyruvate dehydrogenase complex (PDH) deficiency, Exon, Genetics, Humans, Missense mutation, Pyruvate Dehydrogenase (Lipoamide), Child, Pyruvate Dehydrogenase Complex Deficiency Disease, Polymorphism, Single-Stranded Conformational, Genetics (clinical), G alpha subunit, chemistry.chemical_classification, Sequence Analysis, DNA, Pyruvate dehydrogenase complex, Leigh syndrome, Molecular biology, Amino acid, chemistry, Child, Preschool, Female, Leigh Disease, Oxidation-Reduction, PDH E1 alpha subunit, Polarography
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المؤلفون: Christine Toulas, Caroline Delmas, Janick Selves, Rosine Guimbaud, Pascal Pujol, Anne-Françoise Tilkin-Mariamé, Stefania Millevoi, Gilles Favre, Françoise Fouque, Adrien Decorsière, Jean-Marc Rey, Edith Chipoulet, Stéphan Vagner
المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Claudius Regaud, CRLCC Institut Claudius Regaud, Equipe 11-E.Moyal/C.Toulas, Service d'anatomie et cytologie pathologiques [Purpan], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Département d'Oncologie Digestive [CHU Toulouse], Hôpital Arnaud de Villeneuve, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Gustave Roussy (IGR)-Université Paris-Sud - Paris 11 (UP11), Institut Gustave Roussy (IGR), Université Paris-Sud - Paris 11 (UP11), This work was supported by INSERM and FRM (Equipe FRM, soutenue par la Fondation Recherche Médicale to S.V.) and the Groupe de Recherche de l’Institut Claudius Regaud (F.F., C.T., S.M., S.V., R.G.). A.D. was a recipient of a studentship from ARC (Association pour la recherche sur le cancer) and FRM., The authors sincerely thank Thomas Filleron for his help in statistical analyses, Chantal Darnau, Pauline Dejean and Isabelle Gitlaw for their efficient technical assistance., Hôpital Arnaud de Villeneuve [CHRU Montpellier], Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]
المصدر: Cell Cycle
Cell Cycle, Taylor & Francis, 2012, 11 (13), pp.2578-2580. ⟨10.4161/cc.20625⟩مصطلحات موضوعية: Polyadenylation, 0302 clinical medicine, MRNA polyadenylation, MESH: DNA-Binding Proteins/genetics, Gene Duplication, Gene duplication, 3' Untranslated Regions, ComputingMilieux_MISCELLANEOUS, Genetics, 0303 health sciences, MESH: Polymorphism, Single Nucleotide, MESH: Gene Duplication, MESH: 3' Untranslated Regions, Lynch syndrome, MESH: Polyadenylation, DNA-Binding Proteins, 030220 oncology & carcinogenesis, MESH: Cell Line, Tumor, MESH: Mutation, Base pair, MESH: HCT116 Cells, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, MESH: DNA-Binding Proteins/metabolism, Polymorphism, Single Nucleotide, 03 medical and health sciences, MESH: Colorectal Neoplasms, Hereditary Nonpolyposis/metabolism, Cell Line, Tumor, medicine, Humans, RNA, Messenger, Molecular Biology, 030304 developmental biology, MESH: Humans, MESH: RNA, Messenger/metabolism, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Cell Biology, MSH6, medicine.disease, HCT116 Cells, Colorectal Neoplasms, Hereditary Nonpolyposis, MESH: Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, MESH: HeLa Cells, Mutation, Developmental Biology, HeLa Cells
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المؤلفون: J E Alouf, Françoise Fouque, Chantal Guidi-Rontani
المصدر: Microbial Pathogenesis. 16:1-14
مصطلحات موضوعية: Staphylococcus aureus, Erythrocytes, Lysis, Bacterial Toxins, Phospholipid, Hemolysin, Biology, Hemolysis, Microbiology, Cell Line, Hemolysin Proteins, chemistry.chemical_compound, Infectious Diseases, Bacterial Proteins, Species Specificity, Lytic cycle, chemistry, Biochemistry, Endopeptidases, Liposomes, Extracellular, Humans, Phosphatidylinositol, Cytolysin, Lipid bilayer
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18
المؤلفون: D. Fontan, Françoise Fouque, I. Redonnet-Vernhet, Runu Dey, Monique Malgat, Cécile Marsac, C Benelli
المصدر: Journal of Inherited Metabolic Disease. 25:325-327
مصطلحات موضوعية: Pyruvate decarboxylation, Pyruvate dehydrogenase kinase, Pyruvate dehydrogenase phosphatase, Biology, Pyruvate dehydrogenase complex, Molecular biology, chemistry.chemical_compound, chemistry, Biochemistry, Genetics, Thiamine, Dihydrolipoyl transacetylase, Branched-chain alpha-keto acid dehydrogenase complex, Genetics (clinical), Thiamine pyrophosphate
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19
المؤلفون: Chantal Benelli, Aurélie Massias, Martine Glorian, Claude Forest, Françoise Fouque, Thomas Cadoudal
المصدر: The Journal of nutrition. 138(6)
مصطلحات موضوعية: Glycerol, Male, medicine.medical_specialty, Adipose Tissue, White, Retinoic acid, Medicine (miscellaneous), Adipose tissue, Biology, Retinoid X receptor, Gene Expression Regulation, Enzymologic, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Retinoids, Tretinoin, PCK1, Internal medicine, Adipocyte, medicine, Glyceroneogenesis, Adipocytes, Animals, Humans, Promoter Regions, Genetic, Nutrition and Dietetics, 3T3 Cells, Lipid Metabolism, Rats, Up-Regulation, Retinoic acid receptor, Endocrinology, chemistry, Mutation, Female, Phosphoenolpyruvate Carboxykinase (GTP), medicine.drug
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المؤلفون: Thomas, Cadoudal, Françoise, Fouque, Chantal, Benelli, Claude, Forest
المصدر: Medecine sciences : M/S. 24(4)
مصطلحات موضوعية: Glycerol, Diabetes Mellitus, Type 2, Fatty Acids, Insulin Secretion, Humans, Insulin, Phosphoenolpyruvate Carboxykinase (GTP), Obesity, Insulin Resistance, Energy Metabolism, Lipids