المؤلفون: Bloxham, Conor J., Hulme, Katina D., Fierro, Fabrizio, Fercher, Christian, Pegg, Cassandra L., O'Brien, Shannon L., Foster, Simon R., Short, Kirsty R., Furness, Sebastian G.B., Reichelt, Melissa E., Niv, Masha Y., Thomas, Walter G.

المساهمون: Israel Science Foundation, ARC, Australian Research Council, National Health and Medical Research Council

المصدر: Biochemical Pharmacology ; volume 219, page 115932 ; ISSN 0006-2952

الاتاحة: http://dx.doi.org/10.1016/j.bcp.2023.115932
https://api.elsevier.com/content/article/PII:S0006295223005257?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006295223005257?httpAccept=text/plain

المؤلفون: Bhusal, Ram Prasad, Aryal, Pramod, Devkota, Shankar Raj, Pokhrel, Rina, Gunzburg, Menachem J., Foster, Simon R., Lim, Herman D., Payne, Richard J., Wilce, Matthew C.J., Stone, Martin J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 Mar 01. 119(9), 1-7.

URL الوصول: https://www.jstor.org/stable/27150773

المؤلفون: Pallareti, Lisa, Rath, Tine F, Trapkov, Boris, Tsonkov, Tsonko, Nielsen, Anders Thorup, Harpsøe, Kasper, Gentry, Patrick R, Bräuner-Osborne, Hans, Gloriam, David E, Foster, Simon R

المصدر: Pallareti , L , Rath , T F , Trapkov , B , Tsonkov , T , Nielsen , A T , Harpsøe , K , Gentry , P R , Bräuner-Osborne , H , Gloriam , D E & Foster , S R 2023 , ' Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139 ' , European Journal of Pharmacology , vol. 943 , 175553 . https://doi.org/10.1016/j.ejphar.2023.175553

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/pharmacological-characterization-of-novel-small-molecule-agonists-and-antagonists-for-the-orphan-receptor-gpr139(badec937-fbde-472d-9b41-5c7252923c41).html
https://doi.org/10.1016/j.ejphar.2023.175553
https://curis.ku.dk/ws/files/336198909/1_s2.0_S001429992300064X_main.pdf

المؤلفون: Pokhrel, Rina, Morgan, Alexandra L., Robinson, Harley R., Stone, Martin J., Foster, Simon R.

المساهمون: National Health and Medical Research Council, National Heart Foundation of Australia

المصدر: British Journal of Pharmacology ; volume 181, issue 14, page 2359-2370 ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1111/bph.16052
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.16052
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/bph.16052
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.16052

المؤلفون: Voges, Holly K., Foster, Simon R., Reynolds, Liam, Parker, Benjamin L., Devilée, Lynn, Quaife-Ryan, Gregory A., Fortuna, Patrick R.J., Mathieson, Ellen, Fitzsimmons, Rebecca, Lor, Mary, Batho, Christopher, Reid, Janice, Pocock, Mark, Friedman, Clayton E., Mizikovsky, Dalia, Francois, Mathias, Palpant, Nathan J., Needham, Elise J., Peralta, Marina, Monte-Nieto, Gonzalo del, Jones, Lynelle K., Smyth, Ian M., Mehdiabadi, Neda R., Bolk, Francesca, Janbandhu, Vaibhao, Yao, Ernestene, Harvey, Richard P., Chong, James J.H., Elliott, David A., Stanley, Edouard G., Wiszniak, Sophie, Schwarz, Quenten, James, David E., Mills, Richard J., Porrello, Enzo R., Hudson, James E.

المصدر: Cell Reports ; volume 42, issue 5, page 112322 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2023.112322
https://api.elsevier.com/content/article/PII:S2211124723003339?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124723003339?httpAccept=text/plain

المؤلفون: Franck, Charlotte, Foster, Simon R., Johansen-Leete, Jason, Chowdhury, Sayeeda, Cielesh, Michelle, Bhusal, Ram Prasad, Mackay, Joel P., Larance, Mark, Stone, Martin J., Payne, Richard J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun 01. 117(23), 12657-12664.

URL الوصول: https://www.jstor.org/stable/26968307

المؤلفون: Pokhrel, Rina, Morgan, Alexandra L., Robinson, Harley R., Stone, Martin J., Foster, Simon R.

المصدر: British Journal of Pharmacology; Jul2024, Vol. 181 Issue 14, p2359-2370, 12p

مصطلحات موضوعية: G protein coupled receptors, DRUG receptors, PROTEOMICS, DRUG discovery, CELLULAR signal transduction

المؤلفون: Mills, Richard J, Humphrey, Sean J, Fortuna, Patrick RJ, Lor, Mary, Foster, Simon R, Quaife-Ryan, Gregory A, Johnston, Rebecca L, Dumenil, Troy, Bishop, Cameron, Rudraraju, Rajeev, Rawle, Daniel J, Le, Thuy, Zhao, Wei, Engwerda, Christian R

مصطلحات موضوعية: Biological sciences, Biomedical and clinical sciences, Bromodomain and extraterminal family inhibitors, COVID-19, drug discovery, heart, inflammation

Relation: Cell; Mills, RJ; Humphrey, SJ; Fortuna, PRJ; Lor, M; Foster, SR; Quaife-Ryan, GA; Johnston, RL; Dumenil, T; Bishop, C; Rudraraju, R; Rawle, DJ; Le, T; Zhao, W; Engwerda, CR; et al., BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection., Cell, 2021, 184 (8), pp. 2167-2182.e22; http://hdl.handle.net/10072/404132

الاتاحة: http://hdl.handle.net/10072/404132
https://doi.org/10.1016/j.cell.2021.03.026

المؤلفون: Arsova, Angela, Møller, Thor C., Hellyer, Shane D., Vedel, Line, Foster, Simon R., Hansen, Jakob L., Bräuner-osborne, Hans, Gregory, Karen J.

المصدر: Arsova , A , Møller , T C , Hellyer , S D , Vedel , L , Foster , S R , Hansen , J L , Bräuner-osborne , H & Gregory , K J 2021 , ' Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias ' , Molecular Pharmacology , vol. 99 , no. 5 , pp. 328-241 . https://doi.org/10.1124/molpharm.120.000185

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/positive-allosteric-modulators-of-metabotropic-glutamate-receptor-5-as-tool-compounds-to-study-signaling-bias(13e3b5f3-7ba1-441c-9c4b-3d0830337c58).html
https://doi.org/10.1124/molpharm.120.000185
https://curis.ku.dk/ws/files/260551942/Arsova2021_accepted_manuscript_with_figures_and_supplementary.pdf

المؤلفون: Arsova, Angela, Møller, Thor C., Vedel, Line, Hansen, Jakob Lerche, Foster, Simon R., Gregory, Karen J., Bräuner-Osborne, Hans

المصدر: Arsova , A , Møller , T C , Vedel , L , Hansen , J L , Foster , S R , Gregory , K J & Bräuner-Osborne , H 2020 , ' Detailed In Vitro Pharmacological Characterization of Clinically Tested Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5 ' , Molecular Pharmacology , vol. 98 , no. 1 , pp. 49-60 . https://doi.org/10.1124/mol.119.119032

وصف الملف: application/pdf

Relation: https://research.monash.edu/en/publications/4ee2f42c-ec54-4afa-897b-0123c371fb5f

الاتاحة: https://research.monash.edu/en/publications/4ee2f42c-ec54-4afa-897b-0123c371fb5f
https://doi.org/10.1124/mol.119.119032
https://researchmgt.monash.edu/ws/files/313265715/312613629_oa.pdf
http://www.scopus.com/inward/record.url?scp=85086345977&partnerID=8YFLogxK

المؤلفون: Huang, Cheng, Foster, Simon R., Shah, Anup D., Kleifeld, Oded, Canals, Meritxell, Schittenhelm, Ralf B., Stone, Martin J.

مصطلحات موضوعية: Cell Biology, Biochemistry, Molecular Biology

Relation: https://nottingham-repository.worktribe.com/output/4247624; Journal of Biological Chemistry; Volume 295; Pagination 6518-6531; https://nottingham-repository.worktribe.com/file/4247624/1/Phosphoproteomic%20characterization%20of%20the%20signaling%20network

الاتاحة: https://doi.org/10.1074/jbc.ra119.012026
https://nottingham-repository.worktribe.com/file/4247624/1/Phosphoproteomic%20characterization%20of%20the%20signaling%20network
https://nottingham-repository.worktribe.com/output/4247624

المؤلفون: Hauser, Alexander S., Gloriam, David E., Bräuner-Osborne, Hans, Foster, Simon R.

المصدر: Hauser , A S , Gloriam , D E , Bräuner-Osborne , H & Foster , S R 2020 , ' Novel approaches leading towards peptide GPCR de-orphanisation ' , British Journal of Pharmacology , vol. 177 , no. 5 , pp. 961-968 . https://doi.org/10.1111/bph.14950

وصف الملف: application/pdf

Relation: https://research.monash.edu/en/publications/c20dc28d-3518-4abf-95b8-76dd1de12a55

الاتاحة: https://research.monash.edu/en/publications/c20dc28d-3518-4abf-95b8-76dd1de12a55
https://doi.org/10.1111/bph.14950
https://researchmgt.monash.edu/ws/files/299677367/298249030_oa.pdf
http://www.scopus.com/inward/record.url?scp=85078903732&partnerID=8YFLogxK

المؤلفون: Bloxham, Conor J., Foster, Simon R., Thomas, Walter G.

المصدر: Bloxham , C J , Foster , S R & Thomas , W G 2020 , ' A Bitter Taste in Your Heart ' , Frontiers in Physiology , vol. 11 , 431 . https://doi.org/10.3389/fphys.2020.00431

مصطلحات موضوعية: bitter ligands, cardiac physiology, G protein-coupled receptors, polymorphisms, signaling, taste receptors

وصف الملف: application/pdf

Relation: https://research.monash.edu/en/publications/a1cbaeb3-651a-4175-a3d0-847a014d4a0f

الاتاحة: https://research.monash.edu/en/publications/a1cbaeb3-651a-4175-a3d0-847a014d4a0f
https://doi.org/10.3389/fphys.2020.00431
https://researchmgt.monash.edu/ws/files/311473166/310692712_oa.pdf
http://www.scopus.com/inward/record.url?scp=85085104016&partnerID=8YFLogxK

المؤلفون: Foster, Simon R., Hauser, Alexander S., Vedel, Line, Strachan, Ryan T., Huang, Xi Ping, Gavin, Ariana C., Shah, Sushrut D., Nayak, Ajay P., Haugaard-Kedström, Linda M., Penn, Raymond B., Roth, Bryan L., Bräuner-Osborne, Hans, Gloriam, David E.

المصدر: Foster , S R , Hauser , A S , Vedel , L , Strachan , R T , Huang , X P , Gavin , A C , Shah , S D , Nayak , A P , Haugaard-Kedström , L M , Penn , R B , Roth , B L , Bräuner-Osborne , H & Gloriam , D E 2019 , ' Discovery of Human Signaling Systems : Pairing Peptides to G Protein-Coupled Receptors ' , Cell , vol. 179 , no. 4 , pp. 895-908 . https://doi.org/10.1016/j.cell.2019.10.010

مصطلحات موضوعية: deorphanization, endogenous ligand, evolution, genomics, GPCR, machine learning, orphan receptor, peptide ligand, pharmacological screening, receptor internalization

وصف الملف: application/pdf

الاتاحة: https://research.monash.edu/en/publications/fc5a315d-85fb-44be-8089-6cb36492d11c
https://doi.org/10.1016/j.cell.2019.10.010
https://researchmgt.monash.edu/ws/files/290057851/288431042_oa.pdf
http://www.scopus.com/inward/record.url?scp=85074150048&partnerID=8YFLogxK

المؤلفون: Nøhr, Anne Cathrine, Shehata, Mohamed A, Palmer, Daniel, Pokhrel, Rina, Vallianou, Maria, Foster, Simon R, Gentry, Patrick R, Gloriam, David E, Bräuner-Osborne, Hans

المصدر: Nøhr , A C , Shehata , M A , Palmer , D , Pokhrel , R , Vallianou , M , Foster , S R , Gentry , P R , Gloriam , D E & Bräuner-Osborne , H 2019 , ' Identification of a novel scaffold for a small molecule GPR139 receptor agonist ' , Scientific Reports , vol. 9 , no. 1 , 3802 . https://doi.org/10.1038/s41598-019-40085-9

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/identification-of-a-novel-scaffold-for-a-small-molecule-gpr139-receptor-agonist(16b282ff-ad28-4a8e-b32a-6b41c81efd31).html
https://doi.org/10.1038/s41598-019-40085-9
https://curis.ku.dk/ws/files/236372117/s41598_019_40085_9.pdf

المؤلفون: Mos, Iris, Jacobsen, Stine E, Foster, Simon R, Bräuner-Osborne, Hans

المصدر: Mos , I , Jacobsen , S E , Foster , S R & Bräuner-Osborne , H 2019 , ' Calcium-Sensing Receptor Internalization Is β-Arrestin-Dependent and Modulated by Allosteric Ligands ' , Molecular Pharmacology , vol. 96 , no. 4 , pp. 463-474 . https://doi.org/10.1124/mol.119.116772

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/calciumsensing-receptor-internalization-is-arrestindependent-and-modulated-by-allosteric-ligands(68fbd7e4-59ac-4575-b87f-ca7dce8de4a1).html
https://doi.org/10.1124/mol.119.116772
https://curis.ku.dk/ws/files/229104585/463.full.pdf

المؤلفون: Roura, Eugeni, Aldayyani, Asya, Thavaraj, Pridhuvi, Prakash, Sangeeta, Greenway, Delma, Thomas, Walter G., Meyerhof, Wolfgang, Roudnitzky, Natacha, Foster, Simon R.

مصطلحات موضوعية: Original Article

وصف الملف: text/html

Relation: http://chemse.oxfordjournals.org/cgi/content/short/40/6/427; http://dx.doi.org/10.1093/chemse/bjv024

الاتاحة: http://chemse.oxfordjournals.org/cgi/content/short/40/6/427
https://doi.org/10.1093/chemse/bjv024

المؤلفون: Wang, Siyao, Foster, Simon R., Sanchez, Julie, Corcilius, Leo, Larance, Mark, Canals, Meritxell, Stone, Martin J., Payne, Richard J.

مصطلحات موضوعية: Molecular Medicine, Biochemistry, General Medicine

Relation: https://nottingham-repository.worktribe.com/output/5536250; ACS Chemical Biology; Volume 16; Issue 6; Pagination 973-981

الاتاحة: https://doi.org/10.1021/acschembio.1c00006
https://nottingham-repository.worktribe.com/output/5536250

المؤلفون: Foster, Simon R., Porrello, Enzo R., Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D., Moritz, Karen M., Simmons, David G., Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang, Thomas, Walter G.

المساهمون: Ishimaru, Yoshiro

المصدر: PLoS ONE ; volume 8, issue 5, page e64579 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0064579
http://dx.plos.org/10.1371/journal.pone.0064579

المؤلفون: James, Gregory, Foster, Simon R., Key, Brian, Beverdam, Annemiek

المساهمون: Labrador, Juan-Pablo

المصدر: PLoS ONE ; volume 8, issue 9, page e74115 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0074115
http://dx.plos.org/10.1371/journal.pone.0074115