المؤلفون: Martin W. LaFleur, Thao H. Nguyen, Matthew A. Coxe, Kathleen B. Yates, Justin D. Trombley, Sarah A. Weiss, Flavian D. Brown, Jacob E. Gillis, Daniel J. Coxe, John G. Doench, W. Nicholas Haining, Arlene H. Sharpe

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f4cc26f0a06e487587662b0cfb8d4512

المؤلفون: Kevin Bi, Jernej Godec, Arlene H. Sharpe, Frank A. Schildberg, Illana A. Stanley, Debattama R. Sen, Flavian D. Brown, Veronika Lukacs-Kornek, Stéphane J. H. Ricoult, Varun N. Kapoor, Nika N. Danial, W. Nicholas Haining, Viviana Cremasco, Brendan D. Manning, Kathleen B. Yates, Shannon J. Turley, Justin D. Trombley, Martin W. LaFleur, Hye-Jung Kim

المصدر: Nat Immunol

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, Cell Survival, Cellular differentiation, medicine.medical_treatment, T cell, Immunology, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Nitric Oxide, Article, Epigenesis, Genetic, Mice, 03 medical and health sciences, 0302 clinical medicine, Reticular cell, medicine, Animals, Immunology and Allergy, Lymph node, Cells, Cultured, Cell Proliferation, Mice, Knockout, Interleukin-6, Cell growth, Chemistry, Cell Differentiation, Fibroblasts, Cellular Reprogramming, Chromatin Assembly and Disassembly, Chromatin, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Cytokine, Gene Expression Regulation, Lymph Nodes, Immunologic Memory, CD8, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22e7710b99828efbfd6c0eec8e85a1f
https://doi.org/10.1038/s41590-019-0515-x

المؤلفون: Scott J. Rodig, Girish S. Naik, Evisa Gjini, Arpit Panda, Kevin Bi, Seth Maleri, Gabriel K. Griffin, W. Nicholas Haining, Martin W. LaFleur, Sarah A. Weiss, Margaret D. Zimmer, Kristen Felt, Robert T. Manguso, Arlene H. Sharpe, F. Stephen Hodi, Yamini V. Virkud, Jeffrey J. Ishizuka, Jenna L. Collier, Ana Lako, Debattama R. Sen, Juhi R. Kuchroo, Michael Manos, Rose Al Abosy, Brian C. Miller, Kathleen B. Yates, Flavian D. Brown, Dawn E. Comstock

المصدر: Nat Immunol

مصطلحات موضوعية: 0301 basic medicine, Programmed Cell Death 1 Receptor, Immunology, Population, Melanoma, Experimental, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, Lymphocytic Choriomeningitis, Biology, complex mixtures, Article, Mice, Congenic, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, Lymphocytic choriomeningitis virus, Immunology and Allergy, Cytotoxic T cell, Antibodies, Blocking, Receptor, education, Progenitor, education.field_of_study, Melanoma, hemic and immune systems, medicine.disease, Lymphocyte Subsets, Blockade, Mice, Inbred C57BL, 030104 developmental biology, Cell culture, Cancer research, Female, human activities, CD8, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb657daf048d058e233c194f4061d44
https://doi.org/10.1038/s41590-019-0312-6

المؤلفون: John G. Doench, Flavian D. Brown, Dawn E. Comstock, Kathleen B. Yates, Juan Dubrot, Robert T. Manguso, Hans W. Pope, W. Nicholas Haining, Austin Ayer, Adrienne H. Long, Arpit Panda, Ian C. Kohnle, Peter P. Du, Margaret D. Zimmer, Erez Y. Levanon, Jeffrey J. Ishizuka, Gabriel K. Griffin, Sarah Kate Lane-Reticker, Kevin Bi, David Kozono, Ilana Buchumenski, Natalie B. Collins, Collins K. Cheruiyot, Brian C. Miller, Emily J. Robitschek, Debattama R. Sen, Arvin Iracheta-Vellve

المصدر: Signal Transduction and Targeted Therapy

مصطلحات موضوعية: 0301 basic medicine, Interferon-Induced Helicase, IFIH1, Adenosine Deaminase, medicine.medical_treatment, T cell, Programmed Cell Death 1 Receptor, Antigen presentation, Melanoma, Experimental, Inflammation, Receptors, G-Protein-Coupled, Mice, 03 medical and health sciences, 0302 clinical medicine, Interferon, Cell Line, Tumor, medicine, Animals, RNA, Double-Stranded, Multidisciplinary, business.industry, Histocompatibility Antigens Class I, RNA-Binding Proteins, Cell Cycle Checkpoints, Immunotherapy, Research Highlight, Immune checkpoint, Blockade, Mice, Inbred C57BL, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Interferons, RNA Editing, CRISPR-Cas Systems, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049eb68cbb778be01462895380b48dd6
https://doi.org/10.1038/s41586-018-0768-9

المؤلفون: Shannon J. Turley, Flavian D. Brown

المصدر: The Journal of Immunology. 194:1389-1394

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Stromal cell, T-Lymphocytes, Immunology, Mesenchymal stem cell, Connective tissue, T lymphocyte, Biology, Lymphocyte Activation, Article, Cell biology, Extracellular matrix, medicine.anatomical_structure, Reticular cell, medicine, Lymph node stromal cell, Animals, Humans, Immunology and Allergy, Lymph Nodes, Stromal Cells, Lymph node

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8655bc9e532f674eb62a3037222619
https://doi.org/10.4049/jimmunol.1402520

المؤلفون: Sarah A. Weiss, Robert T. Manguso, John G. Doench, Arlene H. Sharpe, Natalie B. Collins, Eliezer M. Van Allen, David E. Fisher, Brian C. Miller, David E. Root, Diana Miao, Kathleen B. Yates, Margaret D. Zimmer, W. Nicholas Haining, Martin W. LaFleur, Flavian D. Brown, Jennifer A. Lo, Hans W. Pope, Kevin Bi, Vikram R. Juneja

المصدر: Nature. 547(7664)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, T-Lymphocytes, Antigen presentation, Melanoma, Experimental, Biology, 03 medical and health sciences, Mice, Immune system, Cancer immunotherapy, Interferon, Loss of Function Mutation, medicine, Animals, Humans, Gene Editing, Antigen Presentation, Protein Tyrosine Phosphatase, Non-Receptor Type 2, Multidisciplinary, Melanoma, NF-kappa B, Cancer, Immunotherapy, Genomics, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Immunology, Cancer research, Unfolded Protein Response, Tumor Escape, Interferons, CRISPR-Cas Systems, medicine.drug, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bd734a9b48f342925e5388eef84394
https://pubmed.ncbi.nlm.nih.gov/31853027

المؤلفون: Gabriel K. Griffin, Kathleen B. Yates, F. Stephen Hodi, Kevin Bi, Sarah A. Weiss, Seth Maleri, Robert T. Manguso, Arlene H. Sharpe, Yamini V. Virkud, Evisa Gjini, Kristen Felt, Scott J. Rodig, Debattama R. Sen, Flavian D. Brown, Dawn E. Comstock, Martin W. LaFleur, Brian C. Miller, Rose Al Abosy, Jeffrey J. Ishizuka, W. Nicholas Haining, Jenna L. Collier, Margaret D. Zimmer, Ana Lako, Arpit Panda, Girish S. Naik, Juhi R. Kuchroo, Michael Manos

المصدر: Nature Immunology. 20:1556-1556

مصطلحات موضوعية: business.industry, Immunology, Cancer research, Immunology and Allergy, Medicine, Cytotoxic T cell, business, Tumor control, Blockade

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c262c8a874196ad16dcd3ae04fad42b7
https://doi.org/10.1038/s41590-019-0528-5

المؤلفون: Nir Yosef, W. Nicholas Haining, Debattama R. Sen, Damien C. Tully, Ulrike Gerdemann, Flavian D. Brown, Kathleen B. Yates, Pierre Tonnerre, James Kaminski, R. Anthony Barnitz, Nicole Frahm, Jernej Godec, Makoto Kurachi, Raymond T. Chung, Martin W. LaFleur, Georg M. Lauer, Todd M. Allen, Hsiao-Wei Tsao, E. John Wherry

المصدر: Science (New York, N.Y.), vol 354, iss 6316

مصطلحات موضوعية: 0301 basic medicine, HIV Infections, CD8-Positive T-Lymphocytes, Inbred C57BL, B7-H1 Antigen, Mice, 0302 clinical medicine, Gene expression, Chronic, Genetics, Regulation of gene expression, Gene Editing, Multidisciplinary, Hepatitis C, Chromatin, medicine.anatomical_structure, Infectious Diseases, 030220 oncology & carcinogenesis, Immunotherapy, Infection, Transcription, Enhancer Elements, General Science & Technology, T cell, 1.1 Normal biological development and functioning, Biology, Lymphocytic Choriomeningitis, complex mixtures, Article, 03 medical and health sciences, Genetic, Underpinning research, medicine, Animals, Humans, Cell Lineage, Epigenetics, Enhancer, Gene, Animal, SOXB1 Transcription Factors, Prevention, Human Genome, 030104 developmental biology, Disease Models, Chronic Disease, T-Box Domain Proteins, Immunologic Memory, CD8, Epigenesis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b874be2e611168d2f571c43c663718
https://researchonline.lshtm.ac.uk/id/eprint/4652487/1/nihms866105.pdf

المؤلفون: Hye-Jung Kim, Tobias A. W. Holderried, Torsten B. Meissner, R. Anthony Barnitz, Taras Kreslavsky, Harvey Cantor, W. Nicholas Haining, Howell F. Moffett, Flavian D. Brown, Yasemin Kaygusuz, Susan Chan, Philippe Kastner, Madeleine E. Lemieux

المصدر: Science (New York, N.Y.). 350(6258)

مصطلحات موضوعية: Transgene, Gene Expression, Autoimmunity, Mice, Transgenic, Biology, CD8-Positive T-Lymphocytes, medicine.disease_cause, Kidney, Lymphocyte Activation, T-Lymphocytes, Regulatory, Mice, medicine, STAT5 Transcription Factor, Animals, Transcription factor, Pancreas, STAT5, Multidisciplinary, Effector, FOXP3, Forkhead Transcription Factors, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Liver, T cell differentiation, Immunology, biology.protein, CD8, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b848f9f1dad91df8e2b6c039b4a2184
https://pubmed.ncbi.nlm.nih.gov/30656143

المؤلفون: Shannon J. Turley, Janice M Nieves, Ryan Murray, Biju Parekkadan, Flavian D. Brown, Konstantin Knoblich, J. D'Rozario, Nima Saeidi, Anne L. Fletcher, Frank A. Schildberg, Jessica S Elman, Jillian L. Astarita, Tracy Sp Heng, Richard L. Boyd

المصدر: Science Translational Medicine. 6

مصطلحات موضوعية: Lipopolysaccharides, Population, Nitric Oxide Synthase Type II, Bacteremia, Spleen, Inflammation, Punctures, Article, Proinflammatory cytokine, Sepsis, Mice, Cell Movement, Reticular cell, medicine, Animals, education, Cecum, Ligation, Lymph node, education.field_of_study, business.industry, General Medicine, Fibroblasts, medicine.disease, Survival Analysis, Endotoxemia, Disease Models, Animal, medicine.anatomical_structure, Immunology, Cytokines, Female, Lymph Nodes, Peritoneum, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b669ccbe1d1b5d3e35d59f16b29b4f85
https://doi.org/10.1126/scitranslmed.3009377

المؤلفون: Flavian D. Brown, Kenzie MacIsaac, Shannon J. Turley, Michael P Wu, Michael C. Carroll, Viviana Cremasco, Glenn Dranoff, Matthew C. Woodruff, Jillian L. Astarita, Lotte Spel, Zohreh Amoozgar, Angelo Grauel

المصدر: Cancer Immunology Research. 4:IA23-IA23

مصطلحات موضوعية: Cancer Research, education.field_of_study, Tumor microenvironment, Stromal cell, medicine.medical_treatment, Immunology, Population, Mesenchymal stem cell, Immunotherapy, Biology, Immune system, Cancer immunotherapy, Tumor progression, medicine, Cancer research, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::de1b78d9e8937e118752d2ad6f9886b3
https://doi.org/10.1158/2326-6066.imm2016-ia23