المؤلفون: Kayki-Mutlu, Gizem, Michel, Martin

المصدر: http://lobid.org/resources/99370679168606441#!, 394(5):839-852.

مصطلحات موضوعية: COVID-19, New drugs, United States [MeSH], Humans [MeSH], Review Article, First-in-indication, Animals [MeSH], Drug Approval [MeSH], First-in-class, Pandemics [MeSH], United States Food and Drug Administration [MeSH], Drug Discovery [MeSH], COVID-19 [MeSH], Pharmacology, Clinical/trends [MeSH], FDA

Relation: https://repository.publisso.de/resource/frl:6448009; https://doi.org/10.1007/s00210-021-02085-3; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051285/

الاتاحة: https://repository.publisso.de/resource/frl:6448009
https://doi.org/10.1007/s00210-021-02085-3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051285/

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/journal_contribution/Supporting_figures_and_tables_/16560469

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.s001

المؤلفون: Martin C. Michel, Gizem Kayki-Mutlu

المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology

مصطلحات موضوعية: medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), 610 Medizin, New Drug Approvals, Review Article, Food and drug administration, First-in-indication, 03 medical and health sciences, 0302 clinical medicine, 610 Medical sciences, Pandemic, Drug Discovery, medicine, Animals, Humans, 030212 general & internal medicine, Intensive care medicine, Drug Approval, Pandemics, Pharmacology, First-in-class, Drug discovery, business.industry, United States Food and Drug Administration, COVID-19, General Medicine, United States, New drugs, Mechanism of action, Antisense oligonucleotides, Pharmacology, Clinical, medicine.symptom, business, 030217 neurology & neurosurgery, FDA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb2f065bdbaac10c7fc5260394d41f8
http://europepmc.org/articles/PMC8051285

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/dataset/Large_deletions_detected_in_sequenced_dogs_/16560472

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.s002

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/dataset/Phenotypes_and_candidate_marker_genotype_for_the_beagle_and_the_two_dachshund_populations_studied_/16560478

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.s004

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/dataset/Large_copy_number_variants_detected_in_sequenced_dogs_/16560475

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.s003

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/figure/Accumulation_of_deleterious_alleles_at_highly_conserved_sites_in_cKCs_/16560481

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.g001

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/figure/Candidate_MMVD_risk_variants_affecting_genes_with_known_function_of_potential_relevance_to_MMVD_pathology_/16560484

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.g002

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/figure/Regulatory_variants_near_i_NEBL_i_are_associated_with_early_MMVD_symptoms_/16560487

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.g003

المؤلفون: Erik Axelsson (201248), Ingrid Ljungvall (738379), Priyasma Bhoumik (11378158), Laura Bas Conn (11378161), Eva Muren (11378164), Åsa Ohlsson (7361789), Lisbeth Høier Olsen (8691657), Karolina Engdahl (6497957), Ragnvi Hagman (256721), Jeanette Hanson (468469), Dmytro Kryvokhyzha (3283938), Mats Pettersson (145346), Olivier Grenet (106357), Jonathan Moggs (147210), Alberto Del Rio-Espinola (11378167), Christian Epe (11378170), Bruce Taillon (83179), Nilesh Tawari (6368984), Shrinivas Mane (11378173), Troy Hawkins (2507872), Åke Hedhammar (157748), Philippe Gruet (11378176), Jens Häggström (106597), Kerstin Lindblad-Toh (11607)

مصطلحات موضوعية: Genetics, Molecular Biology, Evolutionary Biology, Ecology, Infectious Diseases, Biological Sciences not elsewhere classified, strictly controlled populations, isoform nebulette expression, first clear indication, evolutionarily conserved sites, derived cell lines, div >< p, candidate variants near, deleterious genetic variation, mmvd via loss, candidate variants, genetic variation, genetic load, genetic consequences, veterinary care, specific diseases, specific breed, selective breeding, regulatory potential, random entrapment, potential link, papillary muscle, overall increase, nebl <, mmvd )

Relation: https://figshare.com/articles/dataset/Summary_of_sequencing_and_variant_discovery_/16560490

الاتاحة: https://doi.org/10.1371/journal.pgen.1009726.t001

المؤلفون: Laurent S., Mancia G., Poulter N.

المساهمون: Laurent, S, Mancia, G, Poulter, N

مصطلحات موضوعية: Amlodipine, Calcium channel blocker, Combination, First-line indication, Hypertension, Perindopril, Renin–angiotensin system

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/29927844; info:eu-repo/semantics/altIdentifier/wos/WOS:000442250500021; volume:36; issue:9; firstpage:1915; lastpage:1920; numberofpages:6; journal:JOURNAL OF HYPERTENSION; https://hdl.handle.net/10281/433764; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85056377452

الاتاحة: https://hdl.handle.net/10281/433764
https://doi.org/10.1097/HJH.0000000000001766

المؤلفون: Sterckx, Sigrid

المصدر: EXPERT OPINION ON THERAPEUTIC PATENTS ; ISSN: 1354-3776 ; ISSN: 1744-7674

مصطلحات موضوعية: Languages and Literatures, first medical indication claims, Europe, medical devices, patents, pharmaceuticals, second medical indication claims, supplementary protection certificates

وصف الملف: application/pdf

Relation: https://biblio.ugent.be/publication/6967440; http://hdl.handle.net/1854/LU-6967440; http://dx.doi.org/10.1517/13543776.2015.1038240; https://biblio.ugent.be/publication/6967440/file/6967441

الاتاحة: https://biblio.ugent.be/publication/6967440
http://hdl.handle.net/1854/LU-6967440
https://doi.org/10.1517/13543776.2015.1038240
https://biblio.ugent.be/publication/6967440/file/6967441

المؤلفون: Laurent, S, Mancia, G, Poulter, N, Laurent S., Mancia G., Poulter N.

مصطلحات الفهرس: Amlodipine, Calcium channel blocker, Combination, First-line indication, Hypertension, Perindopril, Renin–angiotensin system, info:eu-repo/semantics/article

URL: https://hdl.handle.net/10281/433764
info:eu-repo/semantics/altIdentifier/pmid/29927844
info:eu-repo/semantics/altIdentifier/wos/WOS:000442250500021
volume:36
issue:9
firstpage:1915
lastpage:1920
numberofpages:6
journal:JOURNAL OF HYPERTENSION