المؤلفون: Fiona K. Middleton, John R. Pollard, Nicola J. Curtin

المصدر: Cancers, Vol 10, Iss 8, p 275 (2018)

مصطلحات موضوعية: ATR, p53, radiation, gemcitabine, cytotoxicity, cell cycle, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: http://www.mdpi.com/2072-6694/10/8/275; https://doaj.org/toc/2072-6694; https://doaj.org/article/5ef8504901914f088b409cb813a0d288

الاتاحة: https://doi.org/10.3390/cancers10080275
https://doaj.org/article/5ef8504901914f088b409cb813a0d288

المؤلفون: Nicola J. Curtin, John Pollard, Fiona K. Middleton

المصدر: Cancers, Vol 10, Iss 8, p 275 (2018)
Cancers
Volume 10
Issue 8

مصطلحات موضوعية: 0301 basic medicine, p53, Cancer Research, Cell cycle checkpoint, DNA repair, DNA damage, lcsh:RC254-282, Article, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, medicine, Cytotoxicity, medicine.diagnostic_test, Kinase, Chemistry, gemcitabine, Cancer, Cell cycle, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, radiation, 030104 developmental biology, ATR, Oncology, 030220 oncology & carcinogenesis, Cancer research, cytotoxicity, cell cycle

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86470362e245f1b1fbd19b665192860c
http://www.mdpi.com/2072-6694/10/8/275

المؤلفون: Ian O. Ellis, Christina Perry, Rachel Doherty, Fiona K. Middleton, Stephen Chan, Emad A. Rakha, Nicola J. Curtin, Arvind Arora, Tarek M. A. Abdel-Fatah, Paul M. Moseley, Tao Chen, Srinivasan Madhusudan, Graham Ball, Devika Agarwal, Andrew R. Green

المصدر: Molecular Oncology. 9:569-585

مصطلحات موضوعية: Cancer Research, Mitotic index, Lymphovascular invasion, Breast Neoplasms, Ataxia Telangiectasia Mutated Proteins, Kaplan-Meier Estimate, Biology, Bioinformatics, Cohort Studies, Phosphoserine, Breast cancer, Stress, Physiological, Cell Line, Tumor, Genetics, medicine, Humans, Neoplasm Invasiveness, Molecular Targeted Therapy, RNA, Messenger, CHEK1, Phosphorylation, skin and connective tissue diseases, Lymph node, Research Articles, Cell Proliferation, Gene knockdown, Reproducibility of Results, General Medicine, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, HEK293 Cells, Phenotype, medicine.anatomical_structure, Oncology, Pleomorphism (cytology), Checkpoint Kinase 1, Multivariate Analysis, Cancer cell, Cancer research, Molecular Medicine, Female, biological phenomena, cell phenomena, and immunity, Protein Kinases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6860b79ae77c5109714fb4cf717994a
https://doi.org/10.1016/j.molonc.2014.10.013

المؤلفون: Peter Stephens, Tao Chen, Fiona K. Middleton, Nicola J. Curtin

المصدر: Drug Discovery Today. 17:194-202

مصطلحات موضوعية: G2 Phase, Cell cycle checkpoint, DNA repair, DNA damage, Drug Evaluation, Preclinical, Antineoplastic Agents, Synthetic lethality, S Phase, Clinical Trials, Phase II as Topic, Neoplasms, Drug Discovery, medicine, Animals, Humans, Cytotoxicity, Protein Kinase Inhibitors, Pharmacology, Clinical Trials, Phase I as Topic, business.industry, Cancer, Cell Cycle Checkpoints, G2-M DNA damage checkpoint, medicine.disease, Cancer cell, Cancer research, biological phenomena, cell phenomena, and immunity, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b29cb7d3d8a813b8152f336f54ba35
https://doi.org/10.1016/j.drudis.2011.12.009

المؤلفون: Rachel Doherty, Emad A. Rakha, Tarek M. A. Abdel-Fatah, Nouf Alsubhi, Nicola J. Curtin, Peter Stephens, Andrew R. Green, Fiona K. Middleton, Stephen Chan, Paul M. Moseley, Mohammed A. Aleskandarany, Arvind Arora, Srinivasan Madhusudan, Ian O. Ellis, Stewart G. Martin

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Ku80, Indoles, DNA Repair, Pyridones, medicine.medical_treatment, RAD51, Breast Neoplasms, Ataxia Telangiectasia Mutated Proteins, Radiation Tolerance, Cohort Studies, 03 medical and health sciences, XRCC1, 0302 clinical medicine, Breast cancer, PARP1, Genetics, medicine, Serine, PTEN, Humans, Sulfones, Phosphorylation, RNA, Small Interfering, Neoplasm Staging, Ku70, biology, General Medicine, Articles, medicine.disease, Up-Regulation, Radiation therapy, DNA-Binding Proteins, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Pyrazines, Checkpoint Kinase 1, Cancer research, biology.protein, MCF-7 Cells, Molecular Medicine, Female, RNA Interference, Neoplasm Recurrence, Local, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab14df8b1dcffc5b1c1dfadf47112ea
https://europepmc.org/articles/PMC5528957/

المؤلفون: Aiste McCormick, Nicola J. Curtin, Sarah E. Fordham, Claire Elstob, Felicity E. B. May, Miranda J. Patterson, Mark Wade, Ashleigh Herriott, Fiona K. Middleton, John Pollard, James M. Allan, Richard J. Edmondson

المصدر: Oncotarget

مصطلحات موضوعية: p53, Ku80, Time Factors, DNA Repair, DNA damage, DNA repair, RAD51, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, CHO Cells, DNA-Activated Protein Kinase, Biology, Transfection, DNA damage response, Gene Expression Regulation, Enzymologic, Proto-Oncogene Proteins c-myc, XRCC1, Cricetulus, Cell Line, Tumor, Cricetinae, Databases, Genetic, Animals, Humans, Molecular Targeted Therapy, Sulfones, Protein Kinase Inhibitors, DNA-PKcs, Genetics, Dose-Response Relationship, Drug, Brain Neoplasms, Gene Expression Profiling, Computational Biology, Nuclear Proteins, Base excision repair, synthetic lethality, G2 Phase Cell Cycle Checkpoints, Gene Expression Regulation, Neoplastic, DNA Repair Enzymes, ATR, Oncology, Pyrazines, Cancer cell, Cancer research, biological phenomena, cell phenomena, and immunity, Glioblastoma, DNA Damage, Signal Transduction, Priority Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6454c73a1d8079256b2ac150725caf
https://pubmed.ncbi.nlm.nih.gov/26486089

المؤلفون: Nicola J. Curtin, Philip Michael Reaper, Fiona K. Middleton, John Pollard, Susanna C. Falcon, Tao Chen

المصدر: Molecular oncology. 9(2)

مصطلحات موضوعية: Male, Cancer Research, Cell cycle checkpoint, animal structures, DNA damage, genetic processes, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, Biology, Peripheral blood mononuclear cell, environment and public health, Flow cytometry, Cell cycle phase, Histones, Genetics, medicine, Biomarkers, Tumor, Humans, Protein Kinase Inhibitors, Research Articles, Whole blood, Gene knockdown, medicine.diagnostic_test, General Medicine, Molecular biology, Neoplasm Proteins, enzymes and coenzymes (carbohydrates), Oncology, Biochemistry, Checkpoint Kinase 1, Molecular Medicine, Phosphorylation, Female, biological phenomena, cell phenomena, and immunity, K562 Cells, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a9a7d143e5a148c6025e7a2ed05a73
https://pubmed.ncbi.nlm.nih.gov/25459351

المؤلفون: Nicola J. Curtin, Fiona K. Middleton

المصدر: Advances in DNA Repair in Cancer Therapy ISBN: 9781461447405

مصطلحات موضوعية: chemistry.chemical_compound, Cell cycle checkpoint, DNA repair, Chemistry, DNA damage, medicine, DNA replication, Cell cycle, Homologous recombination, medicine.disease, Nijmegen breakage syndrome, DNA, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a25fa0e49db9e8df32867f80731c2e43
https://doi.org/10.1007/978-1-4614-4741-2_10

المؤلفون: Tao Chen, Nicola J. Curtin, Fiona K. Middleton, John Pollard

المصدر: Cancer Research. 74:2418-2418

مصطلحات موضوعية: Genetics, Cancer Research, Cell cycle checkpoint, biology, Chemistry, DNA damage, Chinese hamster ovary cell, biology.organism_classification, Chinese hamster, medicine.anatomical_structure, Oncology, Cell culture, medicine, Null cell, Cancer research, Fibroblast, Homologous recombination

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bfba167214401eb651b4085ac0e1a9ed
https://doi.org/10.1158/1538-7445.am2014-2418