المؤلفون: Gahbauer, Stefan, DeLeon, Chelsea, Braz, Joao, Craik, Veronica, Kang, Hye, Wan, Xiaobo, Huang, Xi-Ping, Billesbølle, Christian, Liu, Yongfeng, Che, Tao, Deshpande, Ishan, Fink, Elissa, Kondratov, Ivan, Moroz, Yurii, Roth, Bryan, Basbaum, Allan, Shoichet, Brian, Jewell, Madison, Irwin, John

المصدر: Nature Communications. 14(1)

مصطلحات موضوعية: Humans, Mice, Animals, Dinoprostone, Receptors, Prostaglandin, Phagocytosis, Anti-Inflammatory Agents, Pain, Anti-Inflammatory Agents, Non-Steroidal

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4xz106d7
https://escholarship.org/content/qt4xz106d7/qt4xz106d7.pdf

المؤلفون: Fink, Elissa A, Bardine, Conner, Gahbauer, Stefan, Singh, Isha, Detomasi, Tyler C, White, Kris, Gu, Shuo, Wan, Xiaobo, Chen, Jun, Ary, Beatrice, Glenn, Isabella, O'Connell, Joseph, O'Donnell, Henry, Fajtová, Pavla, Lyu, Jiankun, Vigneron, Seth, Young, Nicholas J, Kondratov, Ivan S, Alisoltani, Arghavan, Simons, Lacy M, Lorenzo‐Redondo, Ramon, Ozer, Egon A, Hultquist, Judd F, O'Donoghue, Anthony J, Moroz, Yurii S, Taunton, Jack, Renslo, Adam R, Irwin, John J, García‐Sastre, Adolfo, Shoichet, Brian K, Craik, Charles S

المصدر: Protein Science. 32(8)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Emerging Infectious Diseases, Infectious Diseases, Coronaviruses, 5.1 Pharmaceuticals, Good Health and Well Being, Humans, COVID-19, SARS-CoV-2, Pandemics, Protease Inhibitors, Molecular Docking Simulation, Viral Nonstructural Proteins, Antiviral Agents, major protease, SARS-COV-2, structure-based inhibitor, discoverydockinganti-viral, Biochemistry and Cell Biology, Computation Theory and Mathematics, Other Information and Computing Sciences, Biophysics, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/61h336z6
https://escholarship.org/content/qt61h336z6/qt61h336z6.pdf

المؤلفون: Singh, Isha, Li, Fengling, Fink, Elissa A, Chau, Irene, Li, Alice, Rodriguez-Hernández, Annía, Glenn, Isabella, Zapatero-Belinchón, Francisco J, Rodriguez, M Luis, Devkota, Kanchan, Deng, Zhijie, White, Kris, Wan, Xiaobo, Tolmachova, Nataliya A, Moroz, Yurii S, Kaniskan, H Ümit, Ott, Melanie, García-Sastre, Adolfo, Jin, Jian, Fujimori, Danica Galonić, Irwin, John J, Vedadi, Masoud, Shoichet, Brian K

المصدر: Journal of Medicinal Chemistry. 66(12)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Emerging Infectious Diseases, Infectious Diseases, Humans, Methyltransferases, SARS-CoV-2, Viral Nonstructural Proteins, COVID-19, RNA, Viral, Exoribonucleases, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9th7x7gc
https://escholarship.org/content/qt9th7x7gc/qt9th7x7gc.pdf

المؤلفون: Fink, Elissa A, Xu, Jun, Hübner, Harald, Braz, Joao M, Seemann, Philipp, Avet, Charlotte, Craik, Veronica, Weikert, Dorothee, Schmidt, Maximilian F, Webb, Chase M, Tolmachova, Nataliya A, Moroz, Yurii S, Huang, Xi-Ping, Kalyanaraman, Chakrapani, Gahbauer, Stefan, Chen, Geng, Liu, Zheng, Jacobson, Matthew P, Irwin, John J, Bouvier, Michel, Du, Yang, Shoichet, Brian K, Basbaum, Allan I, Gmeiner, Peter

المصدر: Science. 377(6614)

مصطلحات موضوعية: Adrenergic alpha-2 Receptor Agonists, Analgesics, Non-Narcotic, Animals, Dexmedetomidine, Drug Design, Drug Discovery, Humans, Ligands, Mice, Molecular Docking Simulation, Pain, Pain Management, Structure-Activity Relationship, Neurosciences, Pain Research, Chronic Pain, General Science & Technology

URL الوصول: https://escholarship.org/uc/item/6r0990sd

المؤلفون: Bender, Brian J, Gahbauer, Stefan, Luttens, Andreas, Lyu, Jiankun, Webb, Chase M, Stein, Reed M, Fink, Elissa A, Balius, Trent E, Carlsson, Jens, Irwin, John J, Shoichet, Brian K

المصدر: Nature Protocols. 16(10)

مصطلحات موضوعية: Theory Of Computation, Information and Computing Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, 5.1 Pharmaceuticals, Molecular Docking Simulation, Software, Drug Discovery, Biological Sciences, Medical and Health Sciences, Bioinformatics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9hs932s0
https://escholarship.org/content/qt9hs932s0/qt9hs932s0.pdf

المؤلفون: Newberry, Robert W, Arhar, Taylor, Costello, Jean, Hartoularos, George C, Maxwell, Alison M, Naing, Zun Zar Chi, Pittman, Maureen, Reddy, Nishith R, Schwarz, Daniel MC, Wassarman, Douglas R, Wu, Taia S, Barrero, Daniel, Caggiano, Christa, Catching, Adam, Cavazos, Taylor B, Estes, Laurel S, Faust, Bryan, Fink, Elissa A, Goldman, Miriam A, Gomez, Yessica K, Gordon, M Grace, Gunsalus, Laura M, Hoppe, Nick, Jaime-Garza, Maru, Johnson, Matthew C, Jones, Matthew G, Kung, Andrew F, Lopez, Kyle E, Lumpe, Jared, Martyn, Calla, McCarthy, Elizabeth E, Miller-Vedam, Lakshmi E, Navarro, Erik J, Palar, Aji, Pellegrino, Jenna, Saylor, Wren, Stephens, Christina A, Strickland, Jack, Torosyan, Hayarpi, Wankowicz, Stephanie A, Wong, Daniel R, Wong, Garrett, Redding, Sy, Chow, Eric D, DeGrado, William F, Kampmann, Martin

المصدر: ACS Chemical Biology. 15(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Parkinson's Disease, Brain Disorders, Neurosciences, Genetics, Neurodegenerative, 2.1 Biological and endogenous factors, Generic health relevance, Amino Acid Sequence, Humans, Mutation, Parkinson Disease, Protein Conformation, Saccharomyces cerevisiae, alpha-Synuclein, Chemical Sciences, Organic Chemistry, Biological sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9k81784d
https://escholarship.org/content/qt9k81784d/qt9k81784d.pdf

المؤلفون: Fink, Elissa A., Xu, Jun, Hübner, Harald, Braz, Joao M., Seemann, Philipp, Avet, Charlotte, Craik, Veronica, Weikert, Dorothee, Schmidt, Maximilian F., Webb, Chase M., Tolmachova, Nataliya A., Moroz, Yurii S., Huang, Xi-Ping, Kalyanaraman, Chakrapani, Gahbauer, Stefan, Chen, Geng, Liu, Zheng, Jacobson, Matthew P., Irwin, John J., Bouvier, Michel, Du, Yang, Shoichet, Brian K., Basbaum, Allan I., Gmeiner, Peter

المصدر: Science ; volume 377, issue 6614 ; ISSN 0036-8075 1095-9203

الاتاحة: http://dx.doi.org/10.1126/science.abn7065
https://www.science.org/doi/pdf/10.1126/science.abn7065

المؤلفون: Fink, Elissa

المساهمون: Shoichet, Brian K

مصطلحات موضوعية: Biophysics, Biology, Chemistry, molecular docking, MPro, Nsp14, pain, polypharmacology, α2A adrenergic receptor

وصف الملف: application/pdf

Relation: qt41n618z3; https://escholarship.org/uc/item/41n618z3; https://escholarship.org/content/qt41n618z3/qt41n618z3.pdf

الاتاحة: https://escholarship.org/uc/item/41n618z3
https://escholarship.org/content/qt41n618z3/qt41n618z3.pdf

المؤلفون: Bender, Brian J., Gahbauer, Stefan, Luttens, Andreas, Lyu, Jiankun, Webb, Chase M., Stein, Reed M., Fink, Elissa A., Balius, Trent E., Carlsson, Jens, Irwin, John J., Shoichet, Brian K.

المصدر: Nature Protocols ; volume 17, issue 1, page 177-177 ; ISSN 1754-2189 1750-2799

الاتاحة: https://doi.org/10.1038/s41596-021-00650-x
https://www.nature.com/articles/s41596-021-00650-x.pdf
https://www.nature.com/articles/s41596-021-00650-x

المؤلفون: Bender, Brian J., Gahbauer, Stefan, Luttens, Andreas, Lyu, Jiankun, Webb, Chase M., Stein, Reed M., Fink, Elissa A., Balius, Trent E., Carlsson, Jens, Irwin, John J., Shoichet, Brian K.

مصطلحات الفهرس: Biochemistry and Molecular Biology, Biokemi och molekylärbiologi, Article in journal, info:eu-repo/semantics/article, text

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-469391
Nature Protocols, 1754-2189, 2021, 16:10, s. 4799-4832

المؤلفون: Zang, Xiaoyu, Peraro, Leila, Davison, Ryan T., Blum, Travis R., Vallabhaneni, Deepak, Fennell, Caitlyn E., Cramer, Stephanie L., Shah, Heli K., Wholly, Deirdre M., Fink, Elissa A., Sivak, Jacob T., Ingalls, Kathryn M., Herr, Chelsea T., Lawson, Vernon E., Burnett, Matthew R., Slade, David J., Cole, Kathryn E., Carle, Sigrid A., Miller, Justin S.

المساهمون: U.S. Department of Health and Human Services, National Science Foundation, Virginia Academy of Science, Camille and Henry Dreyfus Foundation, Virginia's Commonwealth Health Research Board, Research Corp

المصدر: The Journal of Organic Chemistry ; volume 85, issue 12, page 8253-8260 ; ISSN 0022-3263 1520-6904

الاتاحة: http://dx.doi.org/10.1021/acs.joc.0c00854
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00854

المؤلفون: Bender, Brian J., Gahbauer, Stefan, Luttens, Andreas, Lyu, Jiankun, Webb, Chase M., Stein, Reed M., Fink, Elissa A., Balius, Trent E., Carlsson, Jens, Irwin, John J., Shoichet, Brian K.

المصدر: Nature Protocols; Jan2022, Vol. 17 Issue 1, p177-177, 1p