المؤلفون: Domenico Spinelli, Roberta Budriesi, Barbara Cosimelli, Elda Severi, Matteo Micucci, Massimo Baroni, Fabio Fusi, Pierfranco Ioan, Simon Cross, Maria Frosini, Simona Saponara, Rosanna Matucci, Camillo Rosano, Maurizio Viale, Alberto Chiarini, Emanuele Carosati

المصدر: Molecules, Vol 19, Iss 10, Pp 16543-16572 (2014)

مصطلحات موضوعية: 3D-QSAR, docking, Fingerprints for Ligands and Proteins (FLAP), L-Type Calcium Channels (LTCC), multidrug resistance (MDR1), negative inotropic activity, oxadiazolothiazinones, pharmacophore modeling, ternary complex, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/19/10/16543; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/ddf26899b337451bb7cef0ca2fc0bb1d

المؤلفون: Antonio Scilimati, Morena Miciaccia, Thaisa Francielle Souza Domingos, Savina Ferorelli, Plínio Cunha Sathler, Lucio Mendes Cabral, Cristina da Costa Bernardes Araújo, Luiz Cláudio Rodrigues Pereira da Silva, Paola Vitale, Carmela Bonaccorso, Maria Grazia Perrone, Marcelo de Pádula, Cosimo G. Fortuna, Gabriella Silva de Almeida

مصطلحات موضوعية: Models, Molecular, Erythrocytes, Mofezolac, Anti-Inflammatory Agents, 01 natural sciences, chemistry.chemical_compound, Models, Drug Discovery, Chlorocebus aethiops, Moiety, Cytotoxicity, 0303 health sciences, Arachidonic Acid, Anti-Inflammatory Agents, Non-Steroidal, Antiplatelet agents, General Medicine, Cardiovascular diseases, Arachidonic acid, Fingerprints for ligands and proteins, Selectivity, Non-Steroidal, Algorithms, medicine.drug, Protein Binding, Stereochemistry, Drug design, 03 medical and health sciences, Structure-Activity Relationship, medicine, Animals, Humans, Cyclooxygenase Inhibitors, Platelet activation, Blood Coagulation, Vero Cells, 030304 developmental biology, Pharmacology, 010405 organic chemistry, Organic Chemistry, COX-1 and COX-2 selective inhibitors, Molecular, Thrombosis, Isoxazoles, Benzidine, 0104 chemical sciences, chemistry, Cyclooxygenase 2, Cyclooxygenase 1, Protein Multimerization, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b34cbc6db961807c18b321980aeaf4
http://hdl.handle.net/20.500.11769/523566

المؤلفون: Simona Saponara, Massimo Baroni, Domenico Spinelli, Barbara Cosimelli, Elda Severi, Pierfranco Ioan, Camillo Rosano, Roberta Budriesi, Fabio Fusi, Rosanna Matucci, Emanuele Carosati, Simon Cross, Maria Frosini, Maurizio Viale, Alberto Chiarini, Matteo Micucci

المساهمون: Spinelli, D., Budriesi, R., Cosimelli, B., Severi, E., Micucci, M., Baroni, M., Fusi, F., Ioan, P., Cross, S., Frosini, M., Saponara, S., Matucci, R., Rosano, C., Viale, M., Chiarini, A., Carosati, E., Domenico, Spinelli, Roberta, Budriesi, Cosimelli, Barbara, Elda, Severi, Matteo, Micucci, Massimo, Baroni, Fabio, Fusi, Pierfranco, Ioan, Simon, Cro, Maria, Frosini, Simona, Saponara, Rosanna, Matucci, Camillo, Rosano, Maurizio, Viale, Alberto, Chiarini, Emanuele, Carosati

المصدر: Molecules, Vol 19, Iss 10, Pp 16543-16572 (2014)
Molecules
Volume 19
Issue 10
Pages 16543-16572

مصطلحات موضوعية: oxadiazolothiazinones, Pharmaceutical Science, Quantitative Structure-Activity Relationship, Multidrug resistance, ternary complex, Analytical Chemistry, Heterocyclic Compounds, Drug Discovery, Ternary complex, L-type calcium channel, Oxadiazoles, Chemistry, Calcium Channel Blockers, Molecular Docking Simulation, Subfamily B, Chemistry (miscellaneous), docking, Molecular Medicine, ATP Binding Cassette Transporter, Subfamily B, Animals, Guinea Pigs, Heart Atria, Muscle, Smooth, Structural Homology, Protein, Muscle, Smooth, Pharmacophore, structure-activity relationship, L-type calcium channels, oxadiazolothiazinone, P-glycoprotein, Quantitative structure–activity relationship, Stereochemistry, In silico, negative inotropic activity, ATP Binding Cassette Transporter, Fingerprints for Ligands and Proteins (FLAP), L-Type Calcium Channels (LTCC), Article, lcsh:QD241-441, lcsh:Organic chemistry, Homology modeling, Physical and Theoretical Chemistry, multidrug resistance (MDR1), 3D-QSAR, Structural Homology, Virtual screening, Calcium channel, Protein, Organic Chemistry, Combinatorial chemistry, Docking (molecular), pharmacophore modeling

وصف الملف: application/pdf; STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61554762b7203fa9fbc751ecaa3e5b93
https://hdl.handle.net/11576/2696050