يعرض 1 - 20 نتائج من 134 نتيجة بحث عن '"Ferrante, Carino"', وقت الاستعلام: 0.57s تنقيح النتائج
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    المساهمون: Fumero, Giuseppe, Batignani, Giovanni, Cassetta, Edoardo, Ferrante, Carino, Giagu, Stefano, Scopigno, Tullio

    Relation: volume:9; issue:6; firstpage:1; lastpage:11; numberofpages:11; journal:APL PHOTONICS; https://hdl.handle.net/11573/1714449

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    المساهمون: Batignani, Giovanni, Ferrante, Carino, Fumero, Giuseppe, Martinati, Mile, Scopigno, Tullio

    Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001230248900002; volume:4; issue:1; firstpage:1; lastpage:21; numberofpages:21; journal:NATURE REVIEWS METHODS PRIMERS; https://hdl.handle.net/11573/1714001; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85194387906

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    المساهمون: Andrews, David L., Bain, Angus J., Ambrosio, Antonio

    المصدر: Nanophotonics X

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    المصدر: Frontiers in Molecular Biosciences, 9, 986022, (2022-11-23)

    مصطلحات موضوعية: 2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans Emily Schifano 1†, Giorgia Conta 2 ,3†, Adele Preziosi 1, Carino Ferrante 4, Giovanni Batignani 4 ,5, Patrizia Mancini 6, Alberta Tomassini 2 ,3, Fabio Sciubba 2 ,3, Tullio Scopigno 4 ,5, Daniela Uccelletti 1 * and Alfredo Miccheli 2 ,3 1 Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Rome, Italy, 2 Department of Environmental Biology, 3 NMR-based Metabolomics Laboratory of Sapienza (NMLab), 4 Department of Physics, 5 Center for Life Nano- and Neuro- science, Istituto Italiano di Tecnologia, 6 Department of Experimental Medicine, Italy High levels of 2-hydroxyisobutyric acid (2-HIBA) were found in urines of patients with obesity and hepatic steatosis, suggesting a potential involvement of this metabolite in clinical conditions. The gut microbial origin of 2-HIBA was hypothesized, however its actual origin and role in biological processes are still not clear. We investigated how treatment with 2-HIBA affected the physiology of the model organism Caenorhabditis elegans, in both standard and high-glucose diet (HGD) growth conditions, by targeted transcriptomic and metabolomic analyses, Coherent Anti-Stokes Raman Scattering (CARS) and two-photon fluorescence microscopy. In standard conditions, 2-HIBA resulted particularly effective to extend the lifespan, delay ageing processes and stimulate the oxidative stress resistance in wild type nematodes through the activation of insulin/IGF-1 signaling (IIS) and p38 MAPK pathways and, consequently, through a reduction of ROS levels. Moreover

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    المساهمون: Biological and Environmental Science and Engineering (BESE) Division, Bioscience, Bioscience Program, Computer, Electrical and Mathematical Science and Engineering (CEMSE) Division, Computer, Electrical and Mathematical Sciences Division, King Abdullah University of Science and Technology (KAUST), 23955 Thuwal, Saudi Arabia, Label-Free Optical Microscopy for Biology Lab, Physics Department, Politecnico di Milano, Milan, Italy, Electronics, Information, and Bioengineering Department, Politecnico di Milano, Italy, Institute for Photonics and Nanotechnologies, CNR (IFN-CNR), Milan, Italy, Physics Department, Universitá di Roma “La Sapienza,” Roma, Italy, Italian Institute of Technology, Center for Life Nano-and Neuro-Science, Roma, Italy, ENEA, FSN-FISS-SNI Laboratory, Roma, Italy, Italian Institute of Technology, Graphene Labs, Genoa, Italy, Enrico Fermi Research Center, Roma, Italy, Unit of Advanced Optical Microscopy, IRCCS Humanitas Research Hospital, Milan, Italy

    وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

    Relation: De la Cadena, A., Vernuccio, F., Ragni, A., Sciortino, G., Vanna, R., Ferrante, C., Pediconi, N., Valensise, C., Genchi, L., Laptenok, S. P., Doni, A., Erreni, M., Scopigno, T., Liberale, C., Ferrari, G., Sampietro, M., Cerullo, G., & Polli, D. (2022). Broadband stimulated Raman imaging based on multi-channel lock-in detection for spectral histopathology. APL Photonics, 7(7), 076104. https://doi.org/10.1063/5.0093946; APL Photonics; 076104; http://hdl.handle.net/10754/679756