المؤلفون: Cho, Choi-Fong, Farquhar, Charlotte E, Fadzen, Colin M, Scott, Benjamin, Zhuang, Pei, von Spreckelsen, Niklas, Loas, Andrei, Hartrampf, Nina, Pentelute, Bradley L, Lawler, Sean E

المصدر: Cho, Choi-Fong; Farquhar, Charlotte E; Fadzen, Colin M; Scott, Benjamin; Zhuang, Pei; von Spreckelsen, Niklas; Loas, Andrei; Hartrampf, Nina; Pentelute, Bradley L; Lawler, Sean E (2022). A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma. Cancers, 14(9):2207.

مصطلحات موضوعية: Department of Chemistry, 540 Chemistry, Cancer Research, Oncology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/219208/1/cancers_14_02207_v3.pdf; info:pmid/35565337; urn:issn:2072-6694

الاتاحة: https://www.zora.uzh.ch/id/eprint/219208/
https://www.zora.uzh.ch/id/eprint/219208/1/cancers_14_02207_v3.pdf
https://doi.org/10.3390/cancers14092207

المؤلفون: von Spreckelsen, Niklas, Fadzen, Colin M., Hartrampf, Nina, Ghotmi, Yarah, Wolfe, Justin M., Dubey, Shipra, Yang, Bo Yeun, Kijewski, Marie F., Wang, Shuyan, Farquhar, Charlotte, Bergmann, Sonja, Zdioruk, Mykola, Wasserburg, J. Roscoe, Scott, Benjamin, Murrell, Emily, Bononi, Fernanda C., Luyt, Leonard G., DiCarli, Marcelo, Lamfers, Martine L.M., Ligon, Keith L., Chiocca, E. Antonio, Viapiano, Mariano S., Pentelute, Bradley L., Lawler, Sean E., Cho, Choi Fong

المصدر: von Spreckelsen , N , Fadzen , C M , Hartrampf , N , Ghotmi , Y , Wolfe , J M , Dubey , S , Yang , B Y , Kijewski , M F , Wang , S , Farquhar , C , Bergmann , S , Zdioruk , M , Wasserburg , J R , Scott , B , Murrell , E , Bononi , F C , Luyt , L G , DiCarli , M , Lamfers , M L M , Ligon , K L , Chiocca , E A , Viapiano , M ....

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الاتاحة: https://pure.eur.nl/en/publications/0b8af911-572a-45f6-94d7-4cdc5b410b96
https://doi.org/10.1002/adtp.202000244
http://www.scopus.com/inward/record.url?scp=85104211803&partnerID=8YFLogxK
https://dspace.mit.edu/bitstream/1721.1/140314/1/10.1002-adtp.202000244.pdf

المؤلفون: Spreckelsen, Niklas, Fadzen, Colin M., Hartrampf, Nina, Ghotmi, Yarah, Wolfe, Justin M., Dubey, Shipra, Yang, Bo Yeun, Kijewski, Marie F., Wang, Shuyan, Farquhar, Charlotte, Bergmann, Sonja, Zdioruk, Mykola, Wasserburg, J. Roscoe, Scott, Benjamin, Murrell, Emily, Bononi, Fernanda C., Luyt, Leonard G., DiCarli, Marcelo, Lamfers, Martine L. M., Ligon, Keith L., Chiocca, E. Antonio, Viapiano, Mariano S., Pentelute, Bradley L., Lawler, Sean E., Cho, Choi‐Fong

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: Wiley

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1002/adtp.202000244; Advanced Therapeutics; https://hdl.handle.net/1721.1/140314; Spreckelsen, Niklas, Fadzen, Colin M., Hartrampf, Nina, Ghotmi, Yarah, Wolfe, Justin M. et al. 2021. "Targeting Glioblastoma Using a Novel Peptide Specific to a Deglycosylated Isoform of Brevican." Advanced Therapeutics, 4 (4).

الاتاحة: https://hdl.handle.net/1721.1/140314

المؤلفون: Wolfe, Justin, Fadzen, Colin M., Holden, Rebecca Lynn, Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: PMC

مصطلحات موضوعية: General Chemistry, Catalysis

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1002/anie.201801167; Angewandte Chemie International Edition; https://hdl.handle.net/1721.1/123522; Wolfe, Justin M. et al. "Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides." Angewandte Chemie International Edition 57, 17 (February 2018): 4756 © 2018 Wiley

الاتاحة: https://hdl.handle.net/1721.1/123522

المؤلفون: Calligaris, David, Hornburg, Kalvis, Chiocca, E. Antonio, Agar, Nathalie Y. R., Lawler, Sean E., Cho, Choi-Fong, Wolfe, Justin, Fadzen, Colin M., Pentelute, Bradley L.

المساهمون: Massachusetts Institute of Technology. Department of Chemistry, Cho, Choi-Fong, Wolfe, Justin, Fadzen, Colin M., Pentelute, Bradley L.

المصدر: Nature

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1038/NCOMMS15623; Nature Communications; http://hdl.handle.net/1721.1/113429; Cho, Choi-Fong et al. “Blood-Brain-Barrier Spheroids as an in Vitro Screening Platform for Brain-Penetrating Agents.” Nature Communications 8 (June 2017): 15623 © 2017 The Author(s); orcid:0000-0001-9811-4396; orcid:0000-0002-1003-6045; orcid:0000-0002-4139-9578

الاتاحة: http://hdl.handle.net/1721.1/113429

المؤلفون: Wolfe, Justin M., Fadzen, Colin M., Holden, Rebecca L., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

المساهمون: National Institutes of Health, National Science Foundation

المصدر: Angewandte Chemie ; volume 130, issue 17, page 4846-4849 ; ISSN 0044-8249 1521-3757

الاتاحة: http://dx.doi.org/10.1002/ange.201801167
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fange.201801167
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.201801167
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ange.201801167
https://onlinelibrary.wiley.com/doi/am-pdf/10.1002/ange.201801167

المؤلفون: Wolfe, Justin M., Fadzen, Colin M., Choo, Zi-Ning, Holden, Rebecca L., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

المساهمون: Division of Graduate Education, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Sarepta Therapeutics

المصدر: ACS Central Science ; volume 4, issue 4, page 512-520 ; ISSN 2374-7943 2374-7951

الاتاحة: http://dx.doi.org/10.1021/acscentsci.8b00098
http://pubs.acs.org/doi/pdf/10.1021/acscentsci.8b00098
https://pubs.acs.org/doi/pdf/10.1021/acscentsci.8b00098

المؤلفون: Cho, Choi-Fong, Wolfe, Justin M., Fadzen, Colin M., Calligaris, David, Hornburg, Kalvis, Chiocca, E. Antonio, Agar, Nathalie Y. R., Pentelute, Bradley L., Lawler, Sean E.

المصدر: Nature Communications ; volume 8, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/ncomms15623
https://www.nature.com/articles/ncomms15623.pdf
https://www.nature.com/articles/ncomms15623
http://www.nature.com/doifinder/10.1038/ncomms15623

المؤلفون: Schissel, Carly K., Mohapatra, Somesh, Wolfe, Justin M., Fadzen, Colin M., Bellovoda, Kamela, Wu, Chia-Ling, Wood, Jenna A., Malmberg, Annika B., Loas, Andrei, Gómez-Bombarelli, Rafael, Pentelute, Bradley L.

المصدر: PMC

وصف الملف: application/octet-stream

Relation: http://dx.doi.org/10.1038/s41557-021-00766-3; Nature Chemistry; https://hdl.handle.net/1721.1/141196.2; Schissel, Carly K, Mohapatra, Somesh, Wolfe, Justin M, Fadzen, Colin M, Bellovoda, Kamela et al. 2021. "Deep learning to design nuclear-targeting abiotic miniproteins." Nature Chemistry, 13 (10).

الاتاحة: https://hdl.handle.net/1721.1/141196.2

المؤلفون: Massachusetts Institute of Technology. Department of Chemistry, Spreckelsen, Niklas, Fadzen, Colin M., Hartrampf, Nina, Ghotmi, Yarah, Wolfe, Justin M., Dubey, Shipra, Yang, Bo Yeun, Kijewski, Marie F., Wang, Shuyan, Farquhar, Charlotte, Bergmann, Sonja, Zdioruk, Mykola, Wasserburg, J. Roscoe, Scott, Benjamin, Murrell, Emily, Bononi, Fernanda C., Luyt, Leonard G., DiCarli, Marcelo, Lamfers, Martine L. M., Ligon, Keith L., Chiocca, E. Antonio, Viapiano, Mariano S., Pentelute, Bradley L., Lawler, Sean E., Cho, Choi‐Fong

المصدر: Wiley

مصطلحات الفهرس: Article, http://purl.org/eprint/type/JournalArticle

URL: https://hdl.handle.net/1721.1/140314
http://dx.doi.org/10.1002/adtp.202000244
Advanced Therapeutics

المؤلفون: Massachusetts Institute of Technology. Department of Chemistry, Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology. Center for Environmental Health Sciences, Cho, Choi-Fong, Farquhar, Charlotte E., Fadzen, Colin M., Scott, Benjamin, Zhuang, Pei, von Spreckelsen, Niklas, Loas, Andrei, Hartrampf, Nina, Pentelute, Bradley L., Lawler, Sean E.

المصدر: Multidisciplinary Digital Publishing Institute

مصطلحات الفهرس: Article, http://purl.org/eprint/type/JournalArticle

URL: https://hdl.handle.net/1721.1/142518
http://dx.doi.org/10.3390/cancers14092207

المؤلفون: Schissel, Carly K, Mohapatra, Somesh, Wolfe, Justin M, Fadzen, Colin M, Bellovoda, Kamela, Wu, Chia-Ling, Wood, Jenna A, Malmberg, Annika B, Loas, Andrei, Gómez-Bombarelli, Rafael, Pentelute, Bradley L

المصدر: PMC

مصطلحات الفهرس: Article, http://purl.org/eprint/type/JournalArticle

URL: https://hdl.handle.net/1721.1/141196
10.1038/S41557-021-00766-3
Nature Chemistry

المؤلفون: Cho, Choi-Fong; https://orcid.org/0000-0003-1473-9773, Farquhar, Charlotte E, Fadzen, Colin M, Scott, Benjamin, Zhuang, Pei; https://orcid.org/0000-0003-2370-8813, von Spreckelsen, Niklas; https://orcid.org/0000-0002-9873-1711, Loas, Andrei; https://orcid.org/0000-0001-5640-1645, Hartrampf, Nina; https://orcid.org/0000-0003-0875-6390, Pentelute, Bradley L; https://orcid.org/0000-0002-7242-801X, Lawler, Sean E

المصدر: Cho, Choi-Fong; Farquhar, Charlotte E; Fadzen, Colin M; Scott, Benjamin; Zhuang, Pei; von Spreckelsen, Niklas; Loas, Andrei; Hartrampf, Nina; Pentelute, Bradley L; Lawler, Sean E (2022). A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma. Cancers, 14(9):2207.

مصطلحات الفهرس: Department of Chemistry, 540 Chemistry, Cancer Research, Oncology, Journal Article, PeerReviewed, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion

URL: https://www.zora.uzh.ch/id/eprint/219208/
https://www.zora.uzh.ch/id/eprint/219208
10.3390/cancers14092207

المؤلفون: Schissel, Carly K., Mohapatra, Somesh, Wolfe, Justin M., Fadzen, Colin M., Bellovoda, Kamela, Wu, Chia-Ling, Wood, Jenna A., Malmberg, Annika B., Loas, Andrei, Gómez-Bombarelli, Rafael, Pentelute, Bradley L.

المساهمون: National Science Foundation, Abdul Latif Jameel Clinic for Machine Learning in Health, MIT-SenseTime Alliance on Artificial Intelligence, Sarepta Therapeutics

المصدر: Nature Chemistry ; volume 13, issue 10, page 992-1000 ; ISSN 1755-4330 1755-4349

الاتاحة: http://dx.doi.org/10.1038/s41557-021-00766-3
https://www.nature.com/articles/s41557-021-00766-3.pdf
https://www.nature.com/articles/s41557-021-00766-3

المؤلفون: Anderson, Mark A., Dhami, Ranjodh S., Fadzen, Colin M., Molina, George, Taylor, Martin S., Deshpande, Vikram, Qadan, Motaz, Catalano, Onofrio A., Ferrone, Cristina R., Mojtahed, Amirkasra

المصدر: Clinical Imaging ; volume 76, page 46-52 ; ISSN 0899-7071

الاتاحة: http://dx.doi.org/10.1016/j.clinimag.2021.01.036
https://api.elsevier.com/content/article/PII:S0899707121000498?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0899707121000498?httpAccept=text/plain

المؤلفون: Massachusetts Institute of Technology. Department of Chemistry, Koch Institute for Integrative Cancer Research at MIT, Fadzen, Colin M, Wolfe, Justin M, Zhou, Wen, Cho, Choi-Fong, von Spreckelsen, Niklas, Hutchinson, Kathryn T, Lee, Yen-Chun, Chiocca, E Antonio, Lawler, Sean E, Yilmaz, Omer H, Lippard, Stephen J, Pentelute, Bradley L

المصدر: PMC

مصطلحات الفهرس: Article, http://purl.org/eprint/type/JournalArticle

URL: https://hdl.handle.net/1721.1/135410
10.1021/ACS.JMEDCHEM.0C00022
Journal of Medicinal Chemistry

المؤلفون: Fadzen, Colin M., Wolfe, Justin M., Zhou, Wen, Cho, Choi-Fong, von Spreckelsen, Niklas, Hutchinson, Kathryn T., Lee, Yen-Chun, Chiocca, E. Antonio, Lawler, Sean E., Yilmaz, Omer H., Lippard, Stephen J., Pentelute, Bradley L.

مصطلحات موضوعية: ddc:no

Relation: Fadzen, Colin M., Wolfe, Justin M., Zhou, Wen, Cho, Choi-Fong, von Spreckelsen, Niklas orcid:0000-0002-9873-1711 , Hutchinson, Kathryn T., Lee, Yen-Chun, Chiocca, E. Antonio, Lawler, Sean E., Yilmaz, Omer H., Lippard, Stephen J. and Pentelute, Bradley L. (2020). A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain. J. Med. Chem., 63 (13). S. 6741 - 6748. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

الاتاحة: https://kups.ub.uni-koeln.de/32664/

المؤلفون: Bergmann, Sonja, Lawler, Sean E., Qu, Yuan, Fadzen, Colin M., Wolfe, Justin, Regan, Michael S., Pentelute, Bradley L., Agar, Nathalie Y. R., Cho, Choi-Fong

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: PMC

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1038/s41596-018-0066-x; Nature Protocols; https://hdl.handle.net/1721.1/123679; Bergmann, Sonja et al. "Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics." Nature Protocols 13, 12 (December 2018): 2827–2843 © 2018 Springer Nature

الاتاحة: https://hdl.handle.net/1721.1/123679

المؤلفون: Fadzen, Colin M., Holden, Rebecca Lynn, Wolfe, Justin, Choo, Zi-Ning, Schissel, Carly K., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

المساهمون: Massachusetts Institute of Technology. Center for Environmental Health Sciences, Massachusetts Institute of Technology. Department of Chemistry, Koch Institute for Integrative Cancer Research at MIT

المصدر: Prof. Pentelute via Ye Li

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1021/acs.biochem.9b00413; Biochemistry; https://hdl.handle.net/1721.1/128007; Fadzen, Colin M. et al. "Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy." Biochemistry 58, 38 (August 2019): 3980–3989 © 2019 American Chemical Society

الاتاحة: https://hdl.handle.net/1721.1/128007

المؤلفون: Cohen, Daniel Tzvi, Zhang, Chi, Fadzen, Colin M., Mijalis, Alexander James, Hie, Liana, Johnson, Kenneth D., Shriver, Zachary, Plante, Obadiah, Miller, Scott J., Buchwald, Stephen Leffler, Pentelute, Bradley L.

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: PMC

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1038/s41557-018-0154-0; Nature Chemistry; https://hdl.handle.net/1721.1/123668; Cohen, Daniel T. et al. "A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins." Nature Chemistry 11, 1 (November 2018): 78–85 © 2018, The Author(s), under exclusive licence to Springer Nature Limited

الاتاحة: https://hdl.handle.net/1721.1/123668