المؤلفون: Ingrid Fert, Laëtitia Douguet, Benjamin Vesin, Fanny Moncoq, Amandine Noirat, Pierre Authié, Sylvain Ciret, Fabien Le Chevalier, Catherine Blanc, Yakov Vitrenko, Pierre Charneau, Laleh Majlessi, François Anna

المصدر: npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2059-0105

URL الوصول: https://doaj.org/article/5be4580b01cc47c9a59f64f70f8a2add

المؤلفون: Laëtitia Douguet, Ingrid Fert, Jodie Lopez, Benjamin Vesin, Fabien Le Chevalier, Fanny Moncoq, Pierre Authié, Trang‐My Nguyen, Amandine Noirat, Fabien Névo, Catherine Blanc, Maryline Bourgine, David Hardy, François Anna, Laleh Majlessi, Pierre Charneau

المصدر: EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)

مصطلحات موضوعية: early E6‐E7 oncoproteins, immuno‐oncotherapy, intra‐tumoral immune cells, lentiviral vector, tumor microenvironment, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/322a19d1d52f4623ae50d523d363e035

المؤلفون: Fabien Le Chevalier, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, Pascal Belin

المصدر: Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Synthetic biology, Combinatorial biosynthesis, Natural products, 2,5-diketopiperazine, Cyclodipeptide synthase, Cyclodipeptide oxidase, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-020-01432-y; https://doaj.org/toc/1475-2859

URL الوصول: https://doaj.org/article/f25dc7239b8a4460a3d5f4a96e21e08c

المؤلفون: Benjamin Vesin, Pierre Authié, Catherine Blanc, Ingrid Fert, Amandine Noirat, Fabien Le Chevalier, Yu Wei, Min-Wen Ku, Kirill Nemirov, François Anna, David Hardy, Cyril Planchais, Hugo Mouquet, Françoise Guinet, Pierre Charneau, Laleh Majlessi, Maryline Bourgine

المصدر: Vaccines, Vol 11, Iss 1, p 12 (2022)

مصطلحات موضوعية: lentiviral vectors, SARS-CoV-2 variants, intranasal vaccination, mucosal immunity, lung inflammation, cross-neutralization, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-393X/11/1/12; https://doaj.org/toc/2076-393X

URL الوصول: https://doaj.org/article/34cede2634f945f8b23c021e868dce71

المؤلفون: Fadel Sayes, Catherine Blanc, Louis S. Ates, Nathalie Deboosere, Mickael Orgeur, Fabien Le Chevalier, Matthias I. Gröschel, Wafa Frigui, Ok-Ryul Song, Richard Lo-Man, Florence Brossier, Wladimir Sougakoff, Daria Bottai, Priscille Brodin, Pierre Charneau, Roland Brosch, Laleh Majlessi

المصدر: Cell Reports, Vol 23, Iss 4, Pp 1072-1084 (2018)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718305011; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/1d85853904c84b0698247d51802126df

المؤلفون: Barbara Rieck, Giulia Degiacomi, Michael Zimmermann, Alessandro Cascioferro, Francesca Boldrin, Natalie R Lazar-Adler, Andrew R Bottrill, Fabien le Chevalier, Wafa Frigui, Marco Bellinzoni, María-Natalia Lisa, Pedro M Alzari, Liem Nguyen, Roland Brosch, Uwe Sauer, Riccardo Manganelli, Helen M O'Hare

المصدر: PLoS Pathogens, Vol 13, Iss 5, p e1006399 (2017)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/fcfce8ed562f48a58fcab50a5ba17c92

المؤلفون: Fred S Sarfo, Fabien Le Chevalier, N'Guetta Aka, Richard O Phillips, Yaw Amoako, Ivo G Boneca, Pascal Lenormand, Mireille Dosso, Mark Wansbrough-Jones, Romain Veyron-Churlet, Laure Guenin-Macé, Caroline Demangel

المصدر: PLoS Neglected Tropical Diseases, Vol 5, Iss 7, p e1237 (2011)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3139662?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/2d998ecef65346a7ae77ed2dd58d0674

المؤلفون: Fabien Le Chevalier, Pierre Authié, Sébastien Chardenoux, Maryline Bourgine, Benjamin Vesin, Delphine Cussigh, Yohann Sassier, Ingrid Fert, Amandine Noirat, Kirill Nemirov, François Anna, Marion Bérard, Françoise Guinet, David Hardy, Pierre Charneau, François Lemonnier, Francina Langa-Vives, Laleh Majlessi

المساهمون: Laboratoire commun Pasteur-TheraVectys, Institut Pasteur [Paris] (IP)-TheraVectys-Université Paris Cité (UPCité), Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Animalerie Centrale (plateforme) - Central Animal Facility (platform) (C2RA), Lymphocytes et Immunité - Lymphocytes and Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Plate-Forme d’Histopathologie / Histopathology Platform, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur et Theravectys

المصدر: Microbes and Infection
Microbes and Infection, In press, ⟨10.1016/j.micinf.2023.105142⟩

مصطلحات موضوعية: HLA, Infectious Diseases, SARS-CoV-2, [SDV]Life Sciences [q-bio], Immunology, Transgenesis, Omicron variant, Microbiology, COVID-19 animal model

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c299fac6dd7c380545b7ffe1457684
https://hal-pasteur.archives-ouvertes.fr/pasteur-04113334/document

المؤلفون: Fabien Le Chevalier, Pierre Authié, Sébastien Chardenoux, Maryline Bourgine, Benjamin Vesin, Delphine Cussigh, Yohann Sassier, Ingrid Fert, Amandine Noirat, Kirill Nemirov, François Anna, Marion Bérard, Françoise Guinet, David Hardy, Pierre Charneau, François Lemonnier, Francina Langa-Vives, Laleh Majlessi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::13f5cc754198087eb3bdb52aee23b995
https://doi.org/10.1101/2022.12.01.518541

المؤلفون: Benjamin Vesin, Jodie Lopez, Amandine Noirat, Pierre Authié, Ingrid Fert, Fabien Le Chevalier, Fanny Moncoq, Kirill Nemirov, Catherine Blanc, Cyril Planchais, Hugo Mouquet, Françoise Guinet, David Hardy, Christiane Gerke, François Anna, Maryline Bourgine, Laleh Majiessi, Pierre Charneau

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a0e7ded6bd32ab0f1e76f9f96a8eb022
https://doi.org/10.1101/2022.01.30.478159

المؤلفون: Benjamin Vesin, Jodie Lopez, Amandine Noirat, Pierre Authié, Ingrid Fert, Fabien Le Chevalier, Fanny Moncoq, Kirill Nemirov, Catherine Blanc, Cyril Planchais, Hugo Mouquet, Françoise Guinet, David Hardy, Francina Langa Vives, Christiane Gerke, François Anna, Maryline Bourgine, Laleh Majlessi, Pierre Charneau

المساهمون: Laboratoire commun Pasteur-TheraVectys, Institut Pasteur [Paris] (IP)-TheraVectys-Université Paris Cité (UPCité), Immunologie humorale - Humoral Immunology, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Lymphocytes et Immunité - Lymphocytes and Immunity, Plate-Forme d’Histopathologie / Histopathology Platform, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Service développement de l'innovation - Innovation Office, Direction des Applications de la Recherche et des Relations industrielles - The Technology Transfer and Industrial Partnership Department (DARRI), Institut Pasteur [Paris] (IP)-Institut Pasteur [Paris] (IP), This work was supported by TheraVectys and Institut Pasteur., The authors are grateful to Dr. Marie José Quentin-Millet and Estelle Besson (TheraVectys) for discussion and advice, to Magali Tichit and Sabine Maurin for excellent technical assistance in preparing histological sections, to Sébastien Chardenoux (CIGM, Institut Pasteur) for excellent technical assistance in B6.K18-hACE2IP−THV mouse transgenesis, and to Marie Laure Loriquet and Dr. Paul-Henri Consigny (Institut Pasteur Medical Center) for their gift of the leftover Moderna vaccines, not unusable in humans, so that this study did not deprive any individual of a vaccine dose during the COVID-19 pandemic. The SARS-CoV2 variant Delta/2021/I7.2 200 was supplied by the Virus and Immunity Unit (Institut Pasteur, Paris, France) headed by Olivier Schwartz. The SARS-CoV-2 Omicron BA.1 variant was initially supplied by the Virus and Immunity Unit (Institut Pasteur, Paris, France) headed by Olivier Schwartz, and was provided to our laboratory by Matthieu Prot and Etienne Simon-Lorière (G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France)., Majlessi, Laleh

المصدر: Molecular Therapy
Molecular Therapy, 2022, ⟨10.1016/j.ymthe.2022.04.016⟩

مصطلحات موضوعية: COVID-19 Vaccines, lentiviral vaccine, Antibodies, Viral, Mice, [SDV.IMM.VAC] Life Sciences [q-bio]/Immunology/Vaccinology, Drug Discovery, Genetics, mucosal booster vaccine, Animals, Humans, SARS-CoV-2 emerging variants of concern, Lung, Molecular Biology, Pharmacology, Vaccines, Synthetic, Mucous Membrane, SARS-CoV-2, Vaccination, COVID-19, Viral Vaccines, Antibodies, Neutralizing, intranasal vaccination, Molecular Medicine, mucosal immunity, waning anti-COVID-19 immunity, mRNA Vaccines, [SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96997045b6b7237750e8b925352e3291
https://hal-pasteur.archives-ouvertes.fr/pasteur-03695076

المؤلفون: Nicolas Canu, Muriel Gondry, Isabelle Correia, Pascal Belin, Robert Thai, Olivier Lequin, Isabelle Jacques, Pavlina Dubois, Steven G. DuBois, Fabien Le Chevalier, Mireille Moutiez

المساهمون: Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire des biomolécules (LBM UMR 7203), Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Département de Chimie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Chimie Moléculaire de Paris Centre (FR 2769), Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO) (SIMoS), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), This work was supported by the French Alternative Energies and Atomic Energy Commission (CEA), the French National Centre for Scientific Research (CNRS), the Sorbonne University and the French National Research Agency (grant ANR-16-CE29-0026)., We thank Dr Taek Soon Lee and Melanya Gudzeva from the Lawrence Berkeley National Laboratory for providing us with plasmids pJBEI-3085 and pJBEI-3122., ANR-16-CE29-0026,DKP-COMBIBIO,L'utilisation des voies de biosynthèse dépendant des synthases de cyclodipeptides pour obtenir de nouvelles 2,5-dicétopipérazines bioactives(2016), Chimie Moléculaire de Paris Centre (FR 2769), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Département de Chimie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), Institute of Neurosciences and Psychology [Glasgow], University of Glasgow, Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, [SDV]Life Sciences [q-bio], lcsh:Medicine, Context (language use), Diketopiperazines, medicine.disease_cause, Article, Indole Alkaloids, 03 medical and health sciences, 0302 clinical medicine, medicine, Escherichia coli, Moiety, [CHIM]Chemical Sciences, Author Correction, lcsh:Science, 2. Zero hunger, chemistry.chemical_classification, Indole test, Prenylation, Multidisciplinary, Chemistry, Alkaloid, lcsh:R, Bioproduction, 030104 developmental biology, Enzyme, Biocatalysis, lcsh:Q, Mevalonate pathway, Genetic Engineering, Metabolic engineering, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a5335bac05615da5e01450efeb2a44
http://link.springer.com/article/10.1038/s41598-019-45519-y

المؤلفون: Pavlina Dubois, Robert Thai, Mireille Moutiez, Steven G. DuBois, Muriel Gondry, Pascal Belin, Isabelle Correia, Nicolas Canu, Fabien Le Chevalier, Olivier Lequin, Isabelle Jacques

المساهمون: Enzymologie et Biosynthèse Peptidique Non Ribosomale (BIOSYN), Département Microbiologie (Dpt Microbio), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-2 (2019)

مصطلحات موضوعية: Indole test, 0303 health sciences, Multidisciplinary, Chemistry, [SDV]Life Sciences [q-bio], lcsh:R, lcsh:Medicine, medicine.disease_cause, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Biochemistry, Prenylation, medicine, lcsh:Q, lcsh:Science, Reprogramming, Escherichia coli, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8263d20188764cd714303519890bc22a
https://doi.org/10.1038/s41598-019-51404-5

المؤلفون: Roland Brosch, Nathalie Deboosere, Florence Brossier, Richard Lo-Man, Wafa Frigui, Fadel Sayes, Catherine Blanc, Pierre Charneau, Priscille Brodin, Mickael Orgeur, Matthias I. Gröschel, Ok-Ryul Song, Fabien Le Chevalier, Daria Bottai, Louis S. Ates, Wladimir Sougakoff, Laleh Majlessi

المساهمون: Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Virologie moléculaire et Vaccinologie, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Histopathologie humaine et Modèles animaux, Institut Pasteur [Paris] (IP), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University of Pisa - Università di Pisa, This work was supported in part by the Institut Pasteur (PTR 441 to L.M. and P.B.), the Agence National de Recherche (ANR-14-CE08-0017 to L.M. and P.B and ANR-14-JAMR-001-02, ANR-10-LABX-62-IBEID, and ANR-16-CE35-0009 to R.B.), the European Union’s Research and Innovation Program (MM4TB 260872 to R.B. and P.B., TBVAC2020 643381 to R.B. and P.C., and ERC-STG INTRACELLTB 260901 to P.B.), grants from the Fondation pour la Recherche Médicale (DEQ20130326471 and SPF20160936136 to R.B. and M.O.), and contributions from the Feder (12001407 D-AL), Equipex Imaginex BioMed (ANR-10-EQPX-04-01), and the Région Nord Pas de Calais (Convention 12000080) to P.B., ANR-14-CE08-0017,ANTI-TB-NANO,Une galénique ' verte ' à base de nanoparticules de cyclodextrines pour un traitement plus efficace de la tuberculose(2014), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-16-CE35-0009,TBemerg,Naissance d'un tueur: facteurs génétiques et adaptations métaboliques impliquées dans l'émergence des bacilles tuberculeux épidémiques(2016), European Project: 260872,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,MM4TB(2011), European Project: 643381,H2020,H2020-PHC-2014-single-stage,TBVAC2020(2015), European Project: 260901,EC:FP7:ERC,ERC-2010-StG_20091118,INTRACELLTB(2010), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Institut Pasteur [Paris], Centre National de Référence des Mycobactéries et de la Résistance aux Antituberculeux [CHU Pitié-Salpêtrière], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

المصدر: Cell Reports
Cell Reports, 2018, 23 (4), pp.1072-1084. ⟨10.1016/j.celrep.2018.03.125⟩
Cell Reports, Vol 23, Iss 4, Pp 1072-1084 (2018)
Cell Reports, Elsevier Inc, 2018, 23 (4), pp.1072-1084. ⟨10.1016/j.celrep.2018.03.125⟩

مصطلحات موضوعية: 0301 basic medicine, Genetics and Molecular Biology (all), Epitopes, T-Lymphocyte, lentiviral vectors, Biochemistry, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Epitope, Mice, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, mycobacterial virulence factors, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], Bacterial Secretion Systems, reporter T cells, lcsh:QH301-705.5, in vivo antigen presentation, Phagocytes, biology, intracellular bacteria, type VII secretion systems, T-cell hybridomas, 3. Good health, Cell biology, medicine.anatomical_structure, Granuloma, Respiratory Tract, T cell, protein localization, Article, General Biochemistry, Genetics and Molecular Biology, Mycobacterium tuberculosis, 03 medical and health sciences, Immune system, Cell Line, Tumor, medicine, Animals, Secretion, Tuberculosis, Pulmonary, mycobacterium tuberculosis, MHC class II, Intracellular parasite, T-cell receptor, Histocompatibility Antigens Class II, biology.organism_classification, bacterial antigen presentation, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, 030104 developmental biology, Biochemistry, Genetics and Molecular Biology (all), lcsh:Biology (General), [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880262557b7cb79e2e90fed04a48cc6b
https://hal-pasteur.archives-ouvertes.fr/pasteur-02046037/document

المؤلفون: Aniek D. van der Woude, Robin M. Warren, Arnab Pain, Louis S. Ates, Connie R. Jimenez, Anzaan Dippenaar, Jorge Barrios-Payán, Wilbert Bitter, Brenda Marquina-Castillo, Edith N.G. Houben, Roland Brosch, Roy Ummels, Rogelio Hernández-Pando, Dulce Mata-Espinosa, Sander R. Piersma, Carolina Guapillo, Kim van der Kuij, Fabien Le Chevalier

المساهمون: Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), VU University Medical Center [Amsterdam], Stellenbosch University, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico], King Abdullah University of Science and Technology (KAUST), Vrije Universiteit Amsterdam [Amsterdam] (VU), E.N.G.H. was funded by a VIDI grant from the Netherlands Organization of Scientific Research. R.H.-P. was funded by grant CONACyT contract FC 2015-/115 and IMMUNOCANEI grant 253053. A.P. is funded by a faculty baseline funding (BAS/1/1020-01-01) by KAUST. L.S.A., F.L.C. and R.B. acknowledge support by grants ANR-14-JAMR-001-02 and ANR-10-LABX-62-IBEID and the European Union’s Horizon 2020 Research and Innovation Program grant 643381., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 643381,H2020,H2020-PHC-2014-single-stage,TBVAC2020(2015), VU University medical center, Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, AII - Infectious diseases, Medical Microbiology and Infection Prevention, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Molecular Microbiology, Molecular and Cellular Neurobiology, AIMMS

المصدر: Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2018, 3 (2), pp.181-188. ⟨10.1038/s41564-017-0090-6⟩
Nature Microbiology, 3(2), 181-188. Nature Publishing Group
Nature Microbiology, 2018, 3 (2), pp.181-188. ⟨10.1038/s41564-017-0090-6⟩
NATURE MICROBIOLOGY, 3(2), 181-188. Nature Publishing Group
Ates, L S, Dippenaar, A, Ummels, R, Piersma, S R, van der Woude, A D, van der Kuij, K, Le Chevalier, F, Mata-Espinosa, D, Barrios-Payán, J, Marquina-Castillo, B, Guapillo, C, Jiménez, C R, Pain, A, Houben, E N G, Warren, R M, Brosch, R, Hernández-Pando, R & Bitter, W 2018, ' Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis ', NATURE MICROBIOLOGY, vol. 3, no. 2, pp. 181-188 . https://doi.org/10.1038/s41564-017-0090-6
Ates, L S, Dippenaar, A, Ummels, R, Piersma, S R, van der Woude, A D, van der Kuij, K, le Chevalier, F, Mata-Espinosa, D, Barrios-Payán, J, Marquina-Castillo, B, Guapillo, C, Jiménez, C R, Pain, A, Houben, E N G, Warren, R M, Brosch, R, Hernández-Pando, R & Bitter, W 2018, ' Mutations in ppe38 block PE-PGRS secretion and increase virulence of Mycobacterium tuberculosis ', Nature Microbiology, vol. 3, no. 2, pp. 181-188 . https://doi.org/10.1038/s41564-017-0090-6

مصطلحات موضوعية: DNA, Bacterial, 0301 basic medicine, Microbiology (medical), Lineage (genetic), Virulence Factors, Immunology, Virulence, medicine.disease_cause, Applied Microbiology and Biotechnology, Microbiology, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Mycobacterium tuberculosis, 03 medical and health sciences, Bacterial Proteins, SDG 3 - Good Health and Well-being, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], Genetics, medicine, Journal Article, Animals, Humans, Secretion, Tuberculosis, Pulmonary, Phylogeny, Antigens, Bacterial, Mice, Inbred BALB C, Mutation, biology, Membrane Proteins, Cell Biology, Glutamic acid, biology.organism_classification, Phenotype, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, 3. Good health, Disease Models, Animal, 030104 developmental biology, Secretory protein, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Beijing, Type VII Secretion Systems, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89147d00309a8f5efc288e7d132ebee9
https://hal-pasteur.archives-ouvertes.fr/pasteur-02046016

المؤلفون: Jean-Louis Herrmann, Isabelle Poncin, Vincent Le Moigne, Carole Serveau-Avesque, Laura Laencina, Nathalie Soismier, Stéphane Canaan, Roland Brosch, Martin Rottman, Gilles Etienne, Fabienne Girard-Misguich, Jean-Louis Gaillard, Anne-Laure Roux, Fabien Le Chevalier, Jean Claude Bakala N'Goma

المساهمون: Enzymologie interfaciale et de physiologie de la lipolyse (EIPL), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Raymond Poincaré [AP-HP], Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Cellule Pasteur, Université Paris Diderot - Paris 7 (UPD7)-PRES Sorbonne Paris Cité, Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), We thank Vaincre La Mucoviscidose (VLM IC1014 and RF20120600689) and the Région Ile-de-France (Domaine d'Intérêt Majeur Maladies Infectieuses et Emergentes) for funding the postdoctoral fellowship to V.L.M. and a Ph.D. program for F.L.C. We are also grateful for the support from the Centre National de la Recherche Scientifique (CNRS)., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Infection et inflammation (2I), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPC), Vaincre la mucoviscidose (VLM): VLMIC1014 and RF20120600689, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Epidémiologie et Physiopathologie des Infections Microbiennes (EPIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2015, 83 (2), pp.780-791. ⟨10.1128/IAI.02032-14⟩
Infection and Immunity, 2015, 83 (2), pp.780-791. ⟨10.1128/IAI.02032-14⟩
Infection and Immunity, 2015, 83, pp.780-791. ⟨10.1128/iai.02032-14⟩

مصطلحات موضوعية: Cystic Fibrosis, Virulence Factors, [SDV]Life Sciences [q-bio], Immunology, Mycobacterium Infections, Nontuberculous, Mycobacterium chelonae, Virulence, Mycobacterium abscessus, medicine.disease_cause, Microbiology, Mycobacterium, Gene Knockout Techniques, Membrane Lipids, Mice, medicine, Animals, Amoeba, Cells, Cultured, Mice, Inbred BALB C, Base Sequence, biology, Phospholipase C, Macrophages, Mycobacterium smegmatis, Pathogenic bacteria, Sequence Analysis, DNA, bacterial infections and mycoses, biology.organism_classification, Molecular Pathogenesis, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Coculture Techniques, Recombinant Proteins, Infectious Diseases, Type C Phospholipases, bacteria, Protozoa, Parasitology, Genome, Bacterial

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5f6871343a887bcb7e76cf87d678a3
https://doi.org/10.1128/iai.02032-14

المؤلفون: Alessandro Cascioferro, Michael B. Zimmermann, Uwe Sauer, Wafa Frigui, Giulia Degiacomi, Francesca Boldrin, Marco Bellinzoni, Riccardo Manganelli, Natalie R. Lazar-Adler, Helen M. O'Hare, Andrew R. Bottrill, María-Natalia Lisa, Barbara Rieck, Pedro M. Alzari, Fabien Le Chevalier, Liem Nguyen, Roland Brosch

المساهمون: University of Leicester, Universita degli Studi di Padova, Yale University School of Medicine, Pathogénomique mycobactérienne intégrée, Institut Pasteur [Paris], Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Montevideo, Réseau International des Instituts Pasteur (RIIP), Case Western Reserve University [Cleveland], Institute for Molecular Systems Biology [ETH Zurich] (IMSB), Department of Biology [ETH Zürich] (D-BIOL), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), We acknowledge financial support from the BBSRC (BB/H007865/10) (HMO), the Agence Nationale pour la Recherche (France) grant 09 BLAN 0400 01 (RB) and the European Commission 260872 (MM4TB) (MB and PMA). This research was, in part, funded by EU FP7 project SysteMTb (MZ and US). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., ANR-09-BLAN-0400,MuKit(2009), European Project: 260872,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,MM4TB(2011), European Project: 241587,EC:FP7:HEALTH,FP7-HEALTH-2009-two-stage,SYSTEMTB(2010), Université Paris Diderot - Paris 7 (UPD7)-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology in Zürich [Zürich] (ETH Zürich)-Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology in Zürich [Zürich] (ETH Zürich), ANR-09-BLAN-0400,MuKit,Development of multiple kinase target (MuKiT) inhibitors for treating tuberculosis(2009), Università degli Studi di Padova = University of Padua (Unipd), Yale School of Medicine [New Haven, Connecticut] (YSM), Institut Pasteur [Paris] (IP), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

المصدر: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2017, 13 (5), pp.e1006399. ⟨10.1371/journal.ppat.1006399⟩
PLoS Pathogens, 13 (5)
PLoS Pathogens, 2017, 13 (5), pp.e1006399. ⟨10.1371/journal.ppat.1006399⟩
PLoS Pathogens, Vol 13, Iss 5, p e1006399 (2017)

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, Amino Acids, Animals, Aspartic Acid, Bacterial Proteins, Glutamic Acid, Homeostasis, Macrophages, Mice, Phosphorylation, Protein-Serine-Threonine Kinases, Tuberculosis, Virulence, Metabolomics, Mycobacterium tuberculosis, Parasitology, Microbiology, Immunology, Molecular Biology, Genetics, Virology, [SDV]Life Sciences [q-bio], 030106 microbiology, Serine, 03 medical and health sciences, Amino acid homeostasis, Protein phosphorylation, Biology (General), biology, RC581-607, biology.organism_classification, 3. Good health, Citric acid cycle, 030104 developmental biology, Immunologic diseases. Allergy, cGMP-dependent protein kinase

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f943836b17f793918750c2a931dd0fe6
https://hal-pasteur.archives-ouvertes.fr/pasteur-01570229

المؤلفون: Roland Brosch, Jean-Louis Herrmann, Alessandro Cascioferro, Fabien Le Chevalier, Laleh Majlessi

المصدر: Future Microbiology. 9:969-985

مصطلحات موضوعية: Microbiology (medical), Tuberculosis, Virulence Factors, Antitubercular Agents, Disease, Microbiology, Evolution, Molecular, Mycobacterium tuberculosis, Pathogenesis, Mice, medicine, Animals, Humans, Molecular Targeted Therapy, Pathogen, Genes, Essential, biology, Treatment regimen, biology.organism_classification, medicine.disease, Virology, Drug development, Genes, Bacterial, Drug Design, Immunology, Mycobacterium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652b93c362ac35db84c087ae9bbf32f9
https://doi.org/10.2217/fmb.14.70

المؤلفون: Guillaume Garnier, Jean-Yves Coppée, Amanda J. Lohan, Mickael Orgeur, Roland Brosch, Jean-Louis Gaillard, Nadine Honoré, Pin Tong, Anne-Laure Roux, Fabien Le Chevalier, Stephen V. Gordon, Alexandre Pawlik, Laurence Ma, Marie-Agnès Dillies, Guillaume Sapriel, Kevin M. Conlon, Christiane Bouchier, Jean-Louis Herrmann, Brendan J. Loftus

المصدر: Molecular Microbiology. 90:612-629

مصطلحات موضوعية: Genetics, 0303 health sciences, biology, 030306 microbiology, Single-nucleotide polymorphism, Locus (genetics), Mycobacterium abscessus, biology.organism_classification, Microbiology, Genome, 3. Good health, Transcriptome, 03 medical and health sciences, Gene cluster, Indel, Molecular Biology, 030304 developmental biology, Mycobacterium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea0be6a0e6bcaa951bc941790051ef67
https://doi.org/10.1111/mmi.12387

المؤلفون: Christian Chalut, Roland Brosch, Catherine Astarie-Dequeker, Christophe Guilhot, Fadel Sayes, Fabien Le Chevalier, Ainhoa Arbues, Jacques Augenstreich, Alice Wegener, Evert Haanappel, Wladimir Malaga, Roxane Simeone

المساهمون: Chimie et Biologie des Membranes et des Nanoobjets (CBMN), Université Sciences et Technologies - Bordeaux 1-École Nationale d'Ingénieurs des Travaux Agricoles - Bordeaux (ENITAB)-Centre National de la Recherche Scientifique (CNRS), Pathogénomique mycobactérienne intégrée, Institut Pasteur [Paris], Laboratoire National des Champs Magnétiques Pulsés (LNCMP), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UPS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie et de biologie structurale (IPBS), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UPS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), This study was in part supported by the European Community's grant TBVAC2020, 643381, the Agence National de Recherche (ANR‐10‐LABX‐62‐IBEID, ANR‐14‐JAMR‐001‐02 and ANR‐16‐CE15‐0003), the Fondation pour la Recherche Médicale FRM (DEQ20090515399, DEQ20130326471 and ING20140129051) and the Centre National de la Recherche Scientifique (CNRS). J.A. is a recipient of a PhD scholarship from the French government., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-14-JAMR-0001,noTBsec,New intervention strategy for tuberculosis: blocking multiple essential targets(2014), ANR-16-CE15-0003,MTBLipVir,Analyse multi-échelle et multidisciplinaire des mécanismes intimes d'action des lipides de virulence de l'enveloppe de Mycobacterium tuberculosis(2016), European Project: 643381,H2020,H2020-PHC-2014-single-stage,TBVAC2020(2015), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)

المصدر: Cellular Microbiology
Cellular Microbiology, Wiley, 2017, 19 (7), pp.e12726. ⟨10.1111/cmi.12726⟩
Cellular Microbiology, 2017, 19 (7), pp.e12726. ⟨10.1111/cmi.12726⟩

مصطلحات موضوعية: 0301 basic medicine, ESX-1, THP-1 Cells, Virulence Factors, [SDV]Life Sciences [q-bio], 030106 microbiology, Immunology, Virulence, Apoptosis, macrophage, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Microbiology, Virulence factor, Mycobacterium, Mycobacterium tuberculosis, 03 medical and health sciences, phthiocerol dimycocerosates, Bacterial Proteins, Virology, Cell Line, Tumor, Phagosomes, Humans, Secretion, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, ComputingMilieux_MISCELLANEOUS, Mycobacterium bovis, Antigens, Bacterial, biology, Macrophages, Cell Membrane, biology.organism_classification, Lipids, 3. Good health, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, tuberculosis, ESAT-6, [SDV.IMM]Life Sciences [q-bio]/Immunology, Bacterial outer membrane, phagosomal membrane rupture

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233f8d3df9945a370d863a0e30e27bee
https://pubmed.ncbi.nlm.nih.gov/28095608