المؤلفون: Xia Yao, Mingquan Xie, Yinyin Ben, Yixiang Zhu, Gaoqiang Yang, Simon Chi Wai Kwong, Zhengliang Zhang, Mark L. Chiu

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)

مصطلحات موضوعية: bispecific antibodies, manufacturing production, controlled Fab-arm exchange, antibody expression, purification, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1298890/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/90ee6ef7c4f749bba1727b5ad757c4af

المؤلفون: Pas, Hendri H., van der Molen, Marije, van Nijen-Vos, Laura, Nijenhuis, Miranda, Bremer, Jeroen

المصدر: Pas , H H , van der Molen , M , van Nijen-Vos , L , Nijenhuis , M & Bremer , J 2024 , ' The Autoimmune IgG Subclass Response Defines the IgG Deposition Pattern in Pemphigus Patient Skin ' , Journal of Investigative Dermatology , vol. 144 , no. 7 , pp. 1649-1650 . https://doi.org/10.1016/j.jid.2023.12.022

مصطلحات موضوعية: Cross-linking, Desmoglein, Fab-arm exchange, IgG4, Monovalent

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/adaa7c2d-c3a5-45c0-8db5-bd40b07032e9
https://research.rug.nl/en/publications/adaa7c2d-c3a5-45c0-8db5-bd40b07032e9
https://doi.org/10.1016/j.jid.2023.12.022
https://pure.rug.nl/ws/files/1082651259/1-s2.0-S0022202X24000289-main.pdf
http://www.scopus.com/inward/record.url?scp=85188206193&partnerID=8YFLogxK

المؤلفون: Nienke Oskam, Timon Damelang, Marij Streutker, Pleuni Ooijevaar-de Heer, Jan Nouta, Carolien Koeleman, Julie Van Coillie, Manfred Wuhrer, Gestur Vidarsson, Theo Rispens

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: antibodies, glycoengineering, fab arm exchange, IgG4-related disease, primary membranous nephropathy, complement activation, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1087532/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/fa7318757d8145ef9a4785fb09b3e46d

المؤلفون: Oskam, Nienke, Damelang, Timon, Streutker, Marij, Ooijevaar-de Heer, Pleuni, Nouta, Jan, Koeleman, Carolien, Van Coillie, Julie, Wuhrer, Manfred, Vidarsson, Gestur, Rispens, Theo

المساهمون: Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

مصطلحات موضوعية: antibodies, complement activation, fab arm exchange, glycoengineering, IgG4-related disease, primary membranous nephropathy, Immunology and Allergy, Immunology

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/435865

الاتاحة: https://dspace.library.uu.nl/handle/1874/435865

المؤلفون: Desislava Yanakieva, Lukas Pekar, Andreas Evers, Markus Fleischer, Stephan Keller, Dirk Mueller-Pompalla, Lars Toleikis, Harald Kolmar, Stefan Zielonka, Simon Krah

المصدر: mAbs, Vol 14, Iss 1 (2022)

مصطلحات موضوعية: cfae, controlled fab arm exchange, duobody, fusion protein, igg-vhh, multispecific, nk cell engager, tetraspecific, trispecific, vhh, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/b8dabdca29ac45818daecc26e6f0571c

المؤلفون: Lu Qin, Lan-Fang Tang, Lei Cheng, Hui-Ying Wang

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: IgG4, Fab-arm exchange, allergen specific immunotherapy, food allergy, eosinophilic esophagitis, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1032909/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/cbe43ce777da4f3781e2064c3df0d5bb

المؤلفون: Inga Koneczny, John Tzartos, Marina Mané-Damas, Vuslat Yilmaz, Maartje G. Huijbers, Konstantinos Lazaridis, Romana Höftberger, Erdem Tüzün, Pilar Martinez-Martinez, Socrates Tzartos, Frank Leypoldt

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: IgG4 autoimmune disease, MHC, autoimmunity, IL-4, IL-10, Fab-arm exchange, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.834342/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/78bc7e200402401ba9ded1519de3fce1

المؤلفون: Basile U., Napodano C., Pocino K., Provenzano C., Ciasca G., Marino M.

المساهمون: Basile, Umberto, Napodano, Cecilia, Gulli, F., Pocino, Krizia, Di Santo, R., Todi, L., Basile, V., Provenzano, Carlo, Ciasca, Gabriele, Marino, Mariapaola

مصطلحات موضوعية: Antibodies, Biomarker, Fab‐arm exchange, Hybrid k/λ, IgG4, MuSK‐MG, Personalized medicine, Settore MED/05 - PATOLOGIA CLINICA

Relation: info:eu-repo/semantics/altIdentifier/pmid/34502051; info:eu-repo/semantics/altIdentifier/wos/WOS:000695581100001; volume:22; issue:17; firstpage:9142; lastpage:9150; numberofpages:9; issueyear:2021; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/10807/190383; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85113736094

الاتاحة: https://hdl.handle.net/10807/190383
https://doi.org/10.3390/ijms22179142

المؤلفون: Thomas A. E. Platts-Mills, Behnam Keshavarz, Jeffrey M. Wilson, Rung-chi Li, Peter W. Heymann, Diane R. Gold, Emily C. McGowan, Elizabeth A. Erwin

المصدر: Children; Volume 8; Issue 5; Pages: 418

مصطلحات موضوعية: food allergy, IgG4 antibody, Fab-arm exchange, eosinophilic esophagitis, milk, wheat, food processing

وصف الملف: application/pdf

Relation: Pediatric Allergy and Immunology; https://dx.doi.org/10.3390/children8050418

الاتاحة: https://doi.org/10.3390/children8050418

المؤلفون: Xia Yao, Mingquan Xie, Yinyin Ben, Yixiang Zhu, Gaoqiang Yang, Simon Chi Wai Kwong, Zhengliang Zhang, Mark L. Chiu

مصطلحات موضوعية: Biotechnology, Biological Engineering, Genetic Engineering, Biomarkers, Biomaterials, Biomechanical Engineering, Biomedical Engineering not elsewhere classified, Synthetic Biology, Agricultural Marine Biotechnology, Bioremediation, Bioprocessing, Bioproduction and Bioproducts, Industrial Biotechnology Diagnostics (incl. Biosensors), Industrial Microbiology (incl. Biofeedstocks), Industrial Molecular Engineering of Nucleic Acids and Proteins, Industrial Biotechnology not elsewhere classified, Medical Biotechnology Diagnostics (incl. Biosensors), Medical Molecular Engineering of Nucleic Acids and Proteins, Regenerative Medicine (incl. Stem Cells and Tissue Engineering), Medical Biotechnology not elsewhere classified, bispecific antibodies, manufacturing production, controlled Fab-arm exchange, antibody expression, purification

Relation: https://figshare.com/articles/dataset/DataSheet1_Large_scale_controlled_Fab_exchange_GMP_process_to_prepare_bispecific_antibodies_PDF/24989985

الاتاحة: https://doi.org/10.3389/fbioe.2023.1298890.s001
https://figshare.com/articles/dataset/DataSheet1_Large_scale_controlled_Fab_exchange_GMP_process_to_prepare_bispecific_antibodies_PDF/24989985

المؤلفون: Michael W. Handlogten, Li Peng, Elizabeth A. Christian, Weichen Xu, Shihua Lin, Raghavan Venkat, William Dall’Acqua, Sanjeev Ahuja

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: antibody reduction, Fab-arm exchange, IgG4, disulfide bond, antibody engineering, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/8d31a924751447b982a0b36561feb01c

المؤلفون: Huang, Shuyu, Segués, Aina, Hulsik, David Lutje, Zaiss, Dietmar M, Sijts, Alice J A M, van Duijnhoven, Sander M J, van Elsas, Andrea

المساهمون: LS Immunologie, Immunologie, dI&I RA-I&I I&I

مصطلحات موضوعية: Bispecific antibody, Antibody chain association, Knobs-into-holes, Charge-pairs, Controlled fab-arm exchange

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/408411

الاتاحة: https://dspace.library.uu.nl/handle/1874/408411

المؤلفون: Jamie Valeich, Dan Boyd, Manu Kanwar, Daniel Stenzel, Deblina De Ghosh, Arpa Ebrahimi, James Woo, Jenny Wang, Alexandre Ambrogelly

المصدر: Antibodies; Volume 9; Issue 4; Pages: 50

مصطلحات موضوعية: monoclonal antibody, mAb, hinge, effector function, Antibody-dependent cellular cytotoxicity (ADCC), IgG4, IgG1, Fcγ receptors, FcγRI, FcγRIII, Fc neonatal receptor, FcRn, Fab arm exchange

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/antib9040050

الاتاحة: https://doi.org/10.3390/antib9040050

المؤلفون: Tim Hofmann, Simon Krah, Carolin Sellmann, Stefan Zielonka, Achim Doerner

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 18; Pages: 6551

مصطلحات موضوعية: bispecific antibodies, high throughput screening, protein trans splicing, inteins, DuoBodies, controlled Fab-arm exchange, Sortase A, microbial transglutaminase, SpyTag, SpyCatcher

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Immunology; https://dx.doi.org/10.3390/ijms21186551

الاتاحة: https://doi.org/10.3390/ijms21186551

المؤلفون: Song-Chou Hsieh, Chieh-Yu Shen, Hsien-Tzung Liao, Ming-Han Chen, Cheng-Han Wu, Ko-Jen Li, Cheng-Shiun Lu, Yu-Min Kuo, Hung-Cheng Tsai, Chang-Youh Tsai, Chia-Li Yu

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 14; Pages: 5082

مصطلحات موضوعية: IgG4-related disease, fibroinflammatory disorder, lymphoplasmacytic infiltration, storiform fibrosis, obliterative phlebitis, modified Th2 response, follicular helper T cell, CD4 + cytotoxic T cell, Fab–arm exchange

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Immunology; https://dx.doi.org/10.3390/ijms21145082

الاتاحة: https://doi.org/10.3390/ijms21145082

المؤلفون: Vergoossen, D.L.E.

المساهمون: Maarel, S.M. van der, Verschuuren, J.J.G.M., Huijbers, M.G.M., Toes, R.E.M., Vermeer, M.H., O'Connor, K.C., Punga, A.R., Leiden University

المصدر: None

مصطلحات موضوعية: IgG4, Autoimmune disease, Valency, Neuromuscular junction, Fab-arm exchange, Epitope, Neuromuscular disease, Myasthenia gravis, Antibodies, MuSK

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2853118564dd1e469f43a0c317aaf4c5
https://hdl.handle.net/1887/3567889

المؤلفون: James Steinhardt, Yanli Wu, Ryan Fleming, Ben T. Ruddle, Pooja Patel, Herren Wu, Changshou Gao, Nazzareno Dimasi

المصدر: Pharmaceutics; Volume 12; Issue 1; Pages: 3

مصطلحات موضوعية: monovalent bispecific antibodies, Fab-arm exchange, protein A binding, high-throughput bispecific generation

وصف الملف: application/pdf

Relation: Biologics and Biosimilars; https://dx.doi.org/10.3390/pharmaceutics12010003

الاتاحة: https://doi.org/10.3390/pharmaceutics12010003

المؤلفون: Nienke Oskam, Timon Damelang, Marij Streutker, Pleuni Ooijevaar-de Heer, Jan Nouta, Carolien Koeleman, Julie Van Coillie, Manfred Wuhrer, Gestur Vidarsson, Theo Rispens

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, antibodies, glycoengineering, fab arm exchange, IgG4-related disease, primary membranous nephropathy, complement activation

Relation: https://figshare.com/articles/dataset/DataSheet_1_Factors_affecting_IgG4-mediated_complement_activation_pdf/21961181

الاتاحة: https://doi.org/10.3389/fimmu.2023.1087532.s001
https://figshare.com/articles/dataset/DataSheet_1_Factors_affecting_IgG4-mediated_complement_activation_pdf/21961181

المؤلفون: Koneczny, Inga, Stevens, Jo A. A., De Rosa, Anna, Huda, Saif, Huijbers, Maartje G., Saxena, Abhishek, Maestri, Michelangelo, Lazaridis, Konstantinos, Zisimopoulou, Paraskevi, Tzartos, Socrates, Verschuuren, Jan, van der Maarel, Silvere M., van Damme, Philip, De Baets, Marc H., Molenaar, Peter C., Vincent, Angela, Ricciardi, Roberta, Martinez-Martinez, Pilar, Losen, Mario

المصدر: Koneczny , I , Stevens , J A A , De Rosa , A , Huda , S , Huijbers , M G , Saxena , A , Maestri , M , Lazaridis , K , Zisimopoulou , P , Tzartos , S , Verschuuren , J , van der Maarel , S M , van Damme , P , De Baets , M H , Molenaar , P C , Vincent , A , Ricciardi , R , Martinez-Martinez , P & Losen , M 2017 , ' IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia ....

مصطلحات موضوعية: Fab-arm exchange, IgG4, MuSK, Myasthenia gravis, Autoimmunity, THROMBOTIC THROMBOCYTOPENIC PURPURA, HUMAN-IMMUNOGLOBULIN-G, PEMPHIGUS-VULGARIS, ACQUIRED NEUROMYOTONIA, ACETYLCHOLINE-RECEPTOR, NEUROMUSCULAR-JUNCTION, SUBCLASS DISTRIBUTION, LIMBIC ENCEPHALITIS, COMPLEMENT ACTIVATION, IMMUNE-COMPLEXES

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/2d74cb42-7941-4568-9549-bf97a67d67b7
https://doi.org/10.1016/j.jaut.2016.11.005

المؤلفون: Saxena, Abhishek, Stevens, Jo, Cetin, Hakan, Koneczny, Inga, Webster, Richard, Lazaridis, Konstantinos, Tzartos, Socrates, Vrolix, Kathleen, Nogales-Gadea, Gisela, Machiels, Barbie, Molenaar, Peter C., Damoiseaux, Jan, De Baets, Marc H., Simon-Keller, Katja, Marx, Alexander, Vincent, Angela, Losen, Mario, Martinez-Martinez, Pilar

المصدر: Saxena , A , Stevens , J , Cetin , H , Koneczny , I , Webster , R , Lazaridis , K , Tzartos , S , Vrolix , K , Nogales-Gadea , G , Machiels , B , Molenaar , P C , Damoiseaux , J , De Baets , M H , Simon-Keller , K , Marx , A , Vincent , A , Losen , M & Martinez-Martinez , P 2017 , ' Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient ' , Scientific Reports , vol. 7 , 14426 ....

مصطلحات موضوعية: ARTHROGRYPOSIS MULTIPLEX CONGENITA, NICOTINIC ACETYLCHOLINE-RECEPTOR, CLASSICAL COMPLEMENT ACTIVATION, FAB-ARM EXCHANGE, NEUROMUSCULAR-JUNCTION, SOMATIC HYPERMUTATION, FETAL ANTIGEN, B-CELLS, THYMUS, AUTOANTIBODIES

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/1611a08e-be32-4bf8-a9d3-57c9cfe3bd86
https://doi.org/10.1038/s41598-017-14350-8