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1Academic Journal
المؤلفون: Delzenne, Nathalie M., Knudsen, Christelle, Beaumont, Martin, Rodriguez, Julie, Neyrinck, Audrey M., Bindels, Laure B.
المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute
المصدر: The Proceedings of the Nutrition Society, Vol. 78, no. 3, p. 319-328 (2019)
مصطلحات موضوعية: ALT alanine aminotransferase, AST aspartate aminotransferase, AhR aryl hydrocarbon receptor, BA bile acid, FXR farnesoid X receptor, GLP glucagon-like peptide, GPR G protein-coupled receptors, ITF inulin-type fructans, LPS lipopolysaccharides, NAFLD non-alcoholic fatty liver disease, NASH non-alcoholic steatohepatitis, Gut microbiota, Inflammation, Non-alcoholic fatty liver disease, Prebiotics
Relation: boreal:212946; http://hdl.handle.net/2078.1/212946; info:pmid/30628563; urn:ISSN:0029-6651; urn:EISSN:1475-2719
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2Academic Journal
المؤلفون: Fava, F, Rizzetto, L, Tuohy, K
المساهمون: Fava, F., Rizzetto, L., Tuohy, K.
مصطلحات موضوعية: BA bile acid, DCA deoxycholic acid, FXR farnesoid X receptor, UDCA ursodeoxycholic acid, Gut microbiota, Bile acids, Fibre, Polyphenols, Short-chain fatty acids, Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
وصف الملف: Elettronico/Electronic
Relation: info:eu-repo/semantics/altIdentifier/pmid/30561288; info:eu-repo/semantics/altIdentifier/wos/WOS:000468363700005; volume:78; issue:2; firstpage:177; lastpage:188; journal:PROCEEDINGS OF THE NUTRITION SOCIETY; http://hdl.handle.net/10449/52443; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85065083483
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3
المؤلفون: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism
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المؤلفون: Songsong Wang, Peng Li, Liang Zou, Jianbo Xiao, Feiya Sheng
المصدر: Journal of Advanced Research
مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, SREBPs, sterol regulatory element binding proteins, SREBP2, sterol regulatory element-binding protein 2, SHP, small heterodimer partner, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, LXRα, liver X receptor α, VLDL, very low-density lipoprotein, Multidisciplinary, TG, triglyceride, Bile acid, Chemistry, Fatty liver, FGF15/19, fibroblast growth factor 15/19, Cholesterol, WB, Western blot, ACC, Acetyl-CoA carboxylase, 030220 oncology & carcinogenesis, Lipogenesis, Quercetin, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, Bile acid metabolism, SDS, sodium dodecyl sulfate, TGR5, Takeda G-protein-coupled receptor 5, medicine.drug_class, Hyperoside, LC-MS, the combination of high-performance liquid chromatography and mass spectrometry, Article, Bile Acids and Salts, pACC, phosphorylated ACC, 03 medical and health sciences, Label-free proteomics, FXR, farnesoid X receptor, CYP27A1, sterol 27-hydroxylase, NAFLD, Internal medicine, medicine, Animals, Cholesterol metabolism, Liver X receptor, ComputingMethodologies_COMPUTERGRAPHICS, BAs, bile acids, SREBP1, sterol regulatory element-binding protein 1, Targeted metabolomics, Lipid Metabolism, CYP7A1, cholesterol 7α-hydroxylase, medicine.disease, Rats, TC, total cholesterol, QC, quality control, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, PMSF, phenylmethylsulfonyl fluoride, Apo, apolipoprotein, BSH, bile salt hydrolase, Farnesoid X receptor
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5
المؤلفون: Michael Goedken, Grace L. Guo, Brian Buckley, Bo Kong, Anita M. Brinker, Rulaiha Elizabeth Taylor, Daniel Rizzolo
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3847-3856 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: DKO, double knockout, WT, wild type, CYP7A1, CYP8B1, sterol 12α-hydroxylase, NTCP, sodium taurocholate cotransporting polypeptide, ASBT, apical sodium-dependent BA transporter, IBABP, intestinal BA-binding protein, 0302 clinical medicine, βMCA, beta muricholic acid, AST, aspartate transaminase, CYP27A1, General Pharmacology, Toxicology and Pharmaceutics, Receptor, LCA, lithocholic acid, 0303 health sciences, CA, cholic acid, Bile acid, Chemistry, OATP, organic anion transporters, Fibroblast growth factor 15, OSTα/β, organic solute transporters alpha and beta, medicine.anatomical_structure, 030220 oncology & carcinogenesis, BA, bile acid, Original Article, Female, Cholestasis of pregnancy, medicine.medical_specialty, medicine.drug_class, RM1-950, Cholesterol 7 alpha-hydroxylase, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, Farnesoid X receptor, CYP27A1, sterol 27-hydroxylase, Internal medicine, ALT, alanine aminotransferase, medicine, BSEP, bile salt export pump, 030304 developmental biology, ALP, alkaline phosphatase, medicine.disease, CYP7A1, cholesterol 7α-hydroxylase, Small intestine, Bile acids, Endocrinology, Nuclear receptor, DCA, deoxycholic acid, CYP7B1, 25-hydroxycholesterol 7-alpha-hydroxylase, Therapeutics. Pharmacology, CYP2C70, cytochrome P450 2C70
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6Academic Journal
المؤلفون: Chang Han
المصدر: International Journal of Molecular Sciences; Volume 19; Issue 7; Pages: 2069
مصطلحات موضوعية: nuclear receptor, FXR (farnesoid X receptor), liver diseases, metabolic disorders, pharmacological application
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Biochemistry; https://dx.doi.org/10.3390/ijms19072069
الاتاحة: https://doi.org/10.3390/ijms19072069
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المؤلفون: Grace L. Guo, Xiaoyun Chen, Zheng Dong, Bilon Khambu, Xiao Ming Yin, Shengmin Yan
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Gut Dysbiosis, OST-β, organic solute transporter subunit-β, SQSTM1, sequestosome-1, FGF15, CK19, cytokeratin 19, Gut flora, FEX, fexaramine, SHP, small heterodimer partner, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, AST, aspartate transaminase, MCA, muricholic acid, CYP8B1, cytochrome p450 family 8b1, BLU, Blu-9931, TCDCA, taurochenodeoxycholic acid, Original Research, FGFR4, fibroblast growth factor receptor 4, TBA, total bile acid, Liver injury, CA, cholic acid, biology, Bile acid, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, NRF2, nuclear factor erythroid 2-related factor 2, BA, bile acid, 030211 gastroenterology & hepatology, TDCA, taurodeoxycholic acid, medicine.drug, medicine.medical_specialty, GM, gut microbiota, ALT, alanine transaminase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, IBABP, ileal bile acid-binding protein, OST-α, organic solute transporter subunit-α, Liver Injury, ASBT (SLC10A2), apical sodium–bile acid transporter, CDCA, chenodeoxycholic acid, Bile Acids and Salts, CYP7A1, cytochrome p450 7a1, 03 medical and health sciences, FXR, farnesoid X receptor, ATG, autophagy-related gene, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Autophagy, BAS, bile acid sequestrants, lcsh:RC799-869, Cholestyramine, ALP, alkaline phosphatase, FGF15, fibroblast growth factor 15, SE, standard error, Hepatology, Fibroblast growth factor receptor 4, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, PCoA, principal coordinates analysis, BSH, bile salt hydrolase, ABX, antibiotics, TLCA, taurolithocholic acid, TMCA, tauromuricholic acid, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease
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المؤلفون: Marica Cariello, Antonio Moschetta, Elena Piccinin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1519-1539 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Peroxisome Proliferator-Activated Receptors, Nuclear Receptors, Receptors, Cytoplasmic and Nuclear, Review, AST, aspartate aminotransferase, RC799-869, FLINT, FXR ligand obeticholic acid for noncirrhotic, nonalcoholic steatohepatitis trial, SHP, small heterodimer partner, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, CCl4, carbon tetrachloride, MUFA, monounsaturated fatty acid, PNPLA3, polymorphisms in patatin-like phospholipase 3, Receptor, NOS, nitric oxide synthase, Liver X Receptors, Peroxisome Proliferator Activated Receptors (PPARs), CA, cholic acid, TNF, tumor necrosis factor, Bile acid, Nonalcoholic Steatohepatitis (NASH), Gastroenterology, SREBP1c, sterol regulatory element-binding protein 1c, WAT, white adipose tissue, NR, nuclear receptor, Diseases of the digestive system. Gastroenterology, Lipids, HSC, hepatic stellate cell, REGENERATE, Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment, OCA, obeticholic acid, NAFL, nonalcoholic fatty liver, BA, bile acid, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, NASH, nonalcoholic steatohepatitis, Metabolic Networks and Pathways, TLR, Toll-like receptor, ATP, adenosine triphosphate, Oxysterol, medicine.drug_class, HDL, high-density lipoprotein, Biology, CYP7A1, cytochrome P450 7A1, Farnesoid X Receptor (FXR), digestive system, APO-E2, apolipoprotein-E2, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, ALT, alanine aminotransferase, Liver X Receptor (LXR), medicine, Animals, Humans, Liver X receptor, SCD1, stearoyl-CoA desaturase 1, PPAR, peroxisome proliferator activated receptor, Hepatology, MCDD, methionine- and choline-deficient diet, medicine.disease, digestive system diseases, FGF, fibroblast growth factor, VLDLR, very-low-density lipoprotein receptor, 030104 developmental biology, CoA, Coenzyme A, Nuclear receptor, Gene Expression Regulation, Cancer research, Farnesoid X receptor, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, LXR, liver X receptor
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9
المؤلفون: Justine Gillard, Laure-Alix Clerbaux, Bart Staels, Anne Tailleux, Isabelle Leclercq, Laure B. Bindels, Maxime Nachit, Christine Sempoux
المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie
المصدر: JHEP reports, vol. 4, no. 1, pp. 100387
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reportsمصطلحات موضوعية: HFD, high-fat diet, CYP7A1, CYP8B1, sterol 12α-hydroxylase, WDF, western and high-fructose diet, FABP6, OGTT, oral glucose tolerance test, FGF15, RC799-869, ASBT, apical sodium-dependent BA transporter, chemistry.chemical_compound, OST, organic solute transporter, βMCA, β-muricholic acid, SHP, small heterodimer protein, WDF, CYP27A1, SHP, TNFα, Immunology and Allergy, LCA, lithocholic acid, DCA, FABP6, fatty acid binding protein 6, FGFR4, fibroblast growth factor receptor 4, CA, cholic acid, NAS, NAFLD activity score, CA, CYP7B1, CYP7B1, oxysterol 7α-hydroxylase, Bile acid, WT, αMCA, ND, normal diet, TGR5, Takeda G-protein coupled receptor 5, Chemistry, LCA, Deoxycholic acid, TLCA, TGR5, Gastroenterology, NASH, GLP-1, glucagon-like peptide-1, Diseases of the digestive system. Gastroenterology, G protein-coupled bile acid receptor, TNFα, tumor necrosis factor α, FXR, BA, bile acid, LPS, lipopolysaccharide, Research Article, CYP2A12, bile acid 7α-hydroxylase, ωMCA, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ωMCA, ω-muricholic acid, LPS, normal diet, Normal diet, βMCA, medicine.drug_class, NASH, non-alcoholic steatohepatitis, education, tumor necrosis factor α, BA, digestive system, metabolic syndrome, CDCA, chenodeoxycholic acid, CYP2A12, CYP27A1, sterol 27-hydroxylase, Internal medicine, NAFLD, Internal Medicine, medicine, OGTT, CYP7A1, cholesterol 7α-hydroxylase, DCA, deoxycholic acid, FGF15, fibroblast growth factor 15, FXR, Farnesoid X receptor, TLCA, tauro-lithocholic acid, WT, wild-type, αMCA, α-muricholic acid, wild-type, CYP8B1, Hepatology, OST, medicine.disease, Endocrinology, NAS, FGFR4, CDCA, HFD, ND, Steatohepatitis, GLP-1, ASBT
وصف الملف: application/pdf
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المؤلفون: Hugo R. de Jonge, Kelly F. Meijsen, Johan W. Jonker, Pauline T. Ikpa, Marcel J. C. Bijvelds, Natascha D.A. Nieuwenhuijze, Henkjan J. Verkade, Marcela Doktorova
المساهمون: Lifestyle Medicine (LM), Center for Liver, Digestive and Metabolic Diseases (CLDM), Gastroenterology & Hepatology
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 1, Pp 47-60 (2020)
Cellular and molecular gastroenterology and hepatology, 9(1), 47-60. HANLEY & BELFUS-ELSEVIER INC
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 9(1), 47-60. Elsevier Inc.مصطلحات موضوعية: 0301 basic medicine, Cystic Fibrosis, Gut flora, Fibroblast growth factor, ACTIVATION, Mice, 0302 clinical medicine, GROWTH-FACTOR 15, Fut2, fuc α1-2 fucosyltransferase, β-MCA, β-muricholic acid, Gut Microbiota, CFTR, Original Research, CA, cholic acid, biology, Chemistry, Microbiota, Gastroenterology, MOUSE MODEL, Intestines, B4galt1, β-1,4-galactosyltransferase I, FXR, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, TLR, Toll-like receptor, Signal Transduction, EXPRESSION, medicine.medical_specialty, BA, bile acid, BILE-ACID HOMEOSTASIS, Cholesterol 7 alpha-hydroxylase, CFLD, cystic fibrosis–related liver disease, Proinflammatory cytokine, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, LIVER-DISEASE, Internal medicine, medicine, Animals, Cytoplasmic and Nuclear Receptors, CFTR, cystic fibrosis transmembrane conductance regulator, lcsh:RC799-869, CF, cystic fibrosis, FAT-ABSORPTION, Hepatology, FGF15, medicine.disease, biology.organism_classification, FGF, fibroblast growth factor, Fibroblast Growth Factors, 030104 developmental biology, Endocrinology, Hepatic stellate cell, RISK-FACTORS, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, ASBT, apical sodium-dependent bile acid transporter, Dysbiosis
وصف الملف: application/pdf
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المؤلفون: Stephanie L. Collins, Andrew D. Patterson
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 19-32 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Enterohepatic circulation, BDE, bromodiphenyl ether, ER, estrogen receptor, GUDCA, glycoursodeoxycholic acid, Microbial metabolism, PCB, polychlorinated biphenyl, Review, SCFA, short chain fatty acid, PD, Parkinson's disease, chemistry.chemical_compound, 0302 clinical medicine, Gastrointestinal tract, NSAID, non-steroidal anti-inflammatory drug, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, cgr, cytochrome glycoside reductase, PXR, pregnane X receptor, BRV, brivudine, CAR, constitutive androgen receptor, CV, conventional, TCDF, 2,3,7,8-tetrachlorodibenzofuran, Cell biology, 030220 oncology & carcinogenesis, CYP, cytochrome P450, PAH, polycyclic aromatic hydrocarbon, SULT, sulfotransferase, SN-38G, SN-38 glucuronide, Biology, BVU, bromovinyluracil, Absorption, 03 medical and health sciences, FXR, farnesoid X receptor, TUDCA, tauroursodeoxycholic acid, Detoxification, Pharmacokinetics, Microbiome, Transcription factor, 030304 developmental biology, Gut microbiome, Bioactivation, UGT, uracil diphosphate-glucuronosyltransferase, lcsh:RM1-950, PABA, p-aminobenzenesulphonamide, PFOS, perfluorooctanesulfonic acid, Metabolism, Xenobiotic metabolism, GF, germ-free, ALDH, aldehyde dehydrogenase, lcsh:Therapeutics. Pharmacology, chemistry, 5-ASA, 5-aminosalicylic acid, AHR, aryl Hydrocarbon Receptor, 5-FU, 5-fluorouracil, Xenobiotic, Drug metabolism
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المؤلفون: Veronika Voronova, Kirill Peskov, Victor Sokolov, Amani Al-Khaifi, Chanchal Kumar, Mats Rudling, Gabriel Helmlinger, Sara Straniero, Bo Angelin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 149-170 (2020)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Malabsorption, OATP, organic anion transporting polypeptide, Physiology-Based Modeling, Gallstones, uBA, unconjugated bile acid, Bile Acids, 0302 clinical medicine, Small intestinal bacterial overgrowth, Enterohepatic Circulation, FGF-19, fibroblast growth factor-19, Bile, Intestinal Mucosa, Enterohepatic circulation, tDCA, taurine-conjugated deoxycholic acid, Farnesoid X Receptor, Original Research, CA, cholic acid, Gastrointestinal tract, Cholesterol 7α-Hydroxylase, Bile acid, Chemistry, Liver Diseases, EHC, enterohepatic circulation, Gastroenterology, Gallbladder, gDCA, glycine-conjugated deoxycholic acid, uCA, unconjugated cholic acid, Editorial, Liver, BA, bile acid, CDCA, сhenodeoxycholic acid, 030211 gastroenterology & hepatology, uCDCA, unconjugated сhenodeoxycholic acid, Diarrhea, uDCA, unconjugated deoxycholic acid, medicine.medical_specialty, Biochemical Phenomena, medicine.drug_class, NTCP, sodium-taurocholate cotransporting polypeptide, Models, Biological, Permeability, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, Metabolic Diseases, Ileum, Internal medicine, gCA, glycine-conjugated cholic acid, tCDCA, taurine-conjugated сhenodeoxycholic acid, medicine, Humans, Fibroblast Growth Factor-19, lcsh:RC799-869, tCA, taurine-conjugated cholic acid, Hepatology, gCDCA, glycine-conjugated сhenodeoxycholic acid, Metabolism, CYP7A1, cholesterol 7α-hydroxylase, Lipid Metabolism, medicine.disease, ODE, ordinary differential equation, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, Intestinal Absorption, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, ASBT, apical sodium-dependent bile acid transporter, Gastrointestinal Motility, Flux (metabolism)
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المؤلفون: Stan F.J. van de Graaf, Reinout L.P. Roscam Abbing, Joanne M. Donkers, Michel van Weeghel, Johannes H.M. Levels, Ronald P.J. Oude Elferink, Anita Boelen, Alfred H. Schinkel
المساهمون: Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases, Experimental Vascular Medicine, ACS - Diabetes & metabolism, Laboratory for Endocrinology, Graduate School
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 451-466 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(3), 451-466. Elsevier Inc.مصطلحات موضوعية: 0301 basic medicine, OATP, organic anion transporting polypeptide, NTCP, 0302 clinical medicine, HFD, high fat diet, Glucagon-Like Peptide 1, VLDL, very low-density lipoprotein, TCDCA, taurochenodeoxycholic acid, Original Research, 2. Zero hunger, OATP, Bile acid, biology, TG, triglyceride, Chemistry, Thyroid, Gastroenterology, ELISA, enzyme-linked immunosorbent assay, cAMP, adenosine 3′,5′-cyclic monophosphate, NTCP, sodium taurocholate co-transporting polypeptide, Glucagon-like peptide-1, G protein-coupled bile acid receptor, 3. Good health, Organic anion-transporting polypeptide, Postprandial, medicine.anatomical_structure, Myrcludex B, GTT, glucose tolerance test, 030211 gastroenterology & hepatology, Dio, deiodinase, medicine.medical_specialty, HDV, hepatitis delta virus, medicine.drug_class, digestive system, Bile Acids and Salts, 03 medical and health sciences, Lipopeptides, FXR, farnesoid X receptor, Hepatitis B, Chronic, Internal medicine, medicine, Humans, Secretion, Obesity, lcsh:RC799-869, PEPCK, Phosphoenolpyruvate carboxykinase, KO, knockout, Hepatology, ALP, alkaline phosphatase, WT, wild-type, BAT, brown adipose tissue, 030104 developmental biology, Endocrinology, HBV, hepatitis B virus, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, FCS, fetal calf serum, NAFLD, nonalcoholic fatty liver disease, TC, taurocholic acid, Hormone
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المؤلفون: Gary D. Wu, Arthur Kastl, Lindsey Albenberg, Natalie A. Terry
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 1, Pp 33-45 (2020)مصطلحات موضوعية: 0301 basic medicine, Disease, Review, Pouchitis, IPAA, ileal pouch–anal anastomosis, SBS, short-bowel syndrome, Irritable Bowel Syndrome, 0302 clinical medicine, Small intestinal bacterial overgrowth, Intestine, Small, Function, Intestinal Mucosa, Irritable bowel syndrome, IBD, inflammatory bowel disease, Microbiota, Gastroenterology, medicine.anatomical_structure, BA, bile acid, Small Intestine, 030211 gastroenterology & hepatology, Sample collection, SIBO, small intestinal bacterial overgrowth, Blind Loop Syndrome, Short Bowel Syndrome, IBS, irritable bowel syndrome, Computational biology, Biology, EED, environmental enteric dysfunction, CFU, colony-forming units, 03 medical and health sciences, FXR, farnesoid X receptor, PN, parenteral nutrition, HF, high-fat, medicine, Dietary Carbohydrates, FAP, familial adenomatous polyposis, Animals, Humans, Microbiome, lcsh:RC799-869, Hepatology, Structure, Feeding Behavior, medicine.disease, Dietary Fats, Small intestine, Gastrointestinal Microbiome, GF, germ-free, UC, ulcerative colitis, Disease Models, Animal, 030104 developmental biology, Dysbiosis, lcsh:Diseases of the digestive system. Gastroenterology
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المؤلفون: Petia Shipkova, Giridhar S. Tirucherai, Arun J. Sanyal, Diane E. Shevell, Benjamin E. Decato, Colleen A. McNaney, Yi Luo, Edgar D. Charles, Abraham Apfel
المصدر: JHEP Reports
مصطلحات موضوعية: GCDCA, glyco-chenodeoxycholic acid, C4, 7α-hydroxy-4-cholesten-3-one, Deoxycholic acid, FGF21, fibroblast growth factor 21, AST, aspartate aminotransferase, PGBF, pegbelfermin, Gastroenterology, chemistry.chemical_compound, FGF21, QD, once daily, Chenodeoxycholic acid, Nonalcoholic fatty liver disease, Immunology and Allergy, LCA, lithocholic acid, CA, cholic acid, Bile acid, LC, liquid chromatography, Fatty liver, baiH, 7β-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, BA, bile acid, Research Article, TCDCA, tauro-chenodeoxycholic acid, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TDCA, tauro-deoxycholic acid, hdhA, 7-alpha-hydroxysteroid dehydrogenase, GUDCA, glyco-ursodeoxycholic acid, Bile salt hydrolase, CYP7A1, cytochrome P450 7A1, PEGylated, polyethylene glycol-conjugated, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, TCA, tauro-cholic acid, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, ALT, alanine aminotransferase, Internal Medicine, medicine, GCA, glyco-cholic acid, C4, Hepatology, business.industry, T2DM, type 2 diabetes mellitus, medicine.disease, GDCA, glyco-deoxycholic acid, QW, once weekly, chemistry, DCA, deoxycholic acid, MS, mass spectrometry, BSH, bile salt hydrolase, baiCD, 7α-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, PRO-C3, N-terminal type III collagen propeptide, HbA1c, glycated haemoglobin, Microbiome, HFF, hepatic fat fraction, Steatosis, Steatohepatitis, business, ApoA1, apolipoprotein A1, Biomarkers
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المؤلفون: Jonel Trebicka, Yasuko Iwakiri
المصدر: JHEP Reports
JHEP reports 3(4), 100316 (2021). doi:10.1016/j.jhepr.2021.100316مصطلحات موضوعية: Cirrhosis, Dll4, delta like canonical Notch ligand 4, HRS, hepatorenal syndrome, PDE, phosphodiesterase, medicine.medical_treatment, Portal venous pressure, PIGF, placental growth factor, Hsp90, heat shock protein 90, AT1R, angiotensin II type I receptor, PKG, cGMP-dependent protein kinase, Review, HSC, MLCP, myosin light-chain phosphatase, Chronic liver disease, Bioinformatics, PDGF, platelet-derived growth factor, angiogenesis, Hepatorenal syndrome, NET, neutrophil extracellular trap, CCl4, carbon tetrachloride, Immunology and Allergy, JAK2, Janus kinase 2, Gastroenterology, eNOS, endothelial nitric oxide synthase, VEGF, VEGF, vascular endothelial growth factor, ECM, extracellular matrix, β1-AR, β1-adrenergic receptor, CCL2, chemokine (C-C motif) ligand 2, FXR, VCAM1, vascular cell adhesion molecule 1, Portal hypertension, NSBB, TIPS, Transjugular intrahepatic portosystemic shunt, EUS, endoscopic ultrasound, HSCs, hepatic stellate cells, NSBBs, non-selective beta blockers, NO, statins, FXR, farnesoid X receptor, TIPS, transjugular intrahepatic portosystemic shunt, Internal Medicine, medicine, ddc:610, LSEC, Rho-kinase, HVPG, hepatic venous pressure gradient, NO, nitric oxide, KO, knockout, Hepatology, business.industry, fibrosis, β2-AR, β2-adrenergic receptor, LSEC, liver sinusoidal endothelial cells, medicine.disease, Review article, liver stiffness, ACE2, angiogenesis-converting enzyme 2, CSPH, clinically significant portal hypertension, ACLF, acute-on-chronic liver failure, CLD, chronic liver disease, Hepatic stellate cell, β-Arr2, β-arrestin 2, business, HCC, hepatocellular carcinoma
وصف الملف: application/octet-stream
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المؤلفون: Shira Zelber-Sagi, Rebecca Dorner, Giulio Marchesini, Marko Korenjak, Christos Lionis, Jeffrey V. Lazarus, Sven Francque, Achim Kautz, Luca Busetto, José Willemse, G. Koek, Dror Dicker, Kate Hallsworth, Shlomo Vinker, Gema Frühbeck, Euan Woodward, Mehmet Ungan, Juan M. Mendive, Martine Walmsley
المساهمون: Francque, Sven M, Marchesini, Giulio, Kautz, Achim, Walmsley, Martine, Dorner, Rebecca, Lazarus, Jeffrey V, Zelber-Sagi, Shira, Hallsworth, Kate, Busetto, Luca, Frühbeck, Gema, Dicker, Dror, Woodward, Euan, Korenjak, Marko, Willemse, José, Koek, Gerardus H, Vinker, Shlomo, Ungan, Mehmet, Mendive, Juan M, Lionis, Christos, Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9), RS: NUTRIM - R2 - Liver and digestive health
المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 5, Pp 100322-(2021)
JHEP Reports, 3(5):100322. Elsevier BVمصطلحات موضوعية: NASH, non-alcoholic steatohepatiti, Y GASTRIC BYPASS, Disease, RC799-869, PLACEBO-CONTROLLED TRIAL, LIFE-STYLE MODIFICATION, cardiovascular disease, LDL, low-density lipoprotein, HEPATOCELLULAR-CARCINOMA, non-invasive test, T2D, GLP-1 RAs, glucagon-like receptor 1 agonists, European Association for the Study of Obesity, HCC, Gastroenterology, NASH, specific, Diseases of the digestive system. Gastroenterology, CAP, controlled attenuation parameter, CT, computed tomography, FXR, ASH, alcoholic steatohepatitis, GP, non-alcoholic steatohepatitis, GLP-1 RAs, glucagon-like receptor 1 agonist, LDL, low-density lipoproteins, medicine.medical_specialty, HDL, achievable, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, high-density lipoprotein, CVD, cardiovascular disease, LDL, Patient Guideline, Quality of life (healthcare), FXR, farnesoid X receptor, NAFLD, low-density lipoproteins, GP, general practitioner, NAFL, non-alcoholic fatty liver, FIB-4, fibrosis-4 index, Intensive care medicine, computed tomography, Guideline, medicine.disease, T1D, type 1 diabete, digestive system diseases, NIT, Human medicine, farnesoid X receptor, type 1 diabetes, BMI, body mass index, EASL, European Association for the Study of the Liver, Placebo-controlled study, Chronic liver disease, GLP-1 RAs, QUALITY-OF-LIFE, alcoholic steatohepatitis, European Association for the Study of Diabetes, EASD, European Association for the Study of Diabetes, Immunology and Allergy, magnetic resonance imaging, NASH Clinical Research Network, ALD, alcohol-related or alcoholic liver disease, Disease management (health), glucagon-like receptor 1 agonists, EASO, European Association for the Study of Obesity, NASH CRN, NASH Clinical Research Network, ASH, alcoholic steatohepatiti, Fatty liver, timely, hepatocellular carcinoma, CVD, magnetic resonance elastography, MRE, NAFL, FIB-4, non-alcoholic fatty liver, type 2 diabetes, T1D, type 1 diabetes, CAP, controlled attenuation parameter, CT, European Association for the Study of the Liver, MRI, fibrosis-4 index, NAFLD, non-alcoholic fatty liver disease, EASD, HDL, high-density lipoprotein, UNITED-STATES, ASH, body mass index, EASL, measurable, BMI, NIT, non-invasive test, Internal Medicine, medicine, NASH CRN, HEPATIC STEATOSIS, HCC, hepatocellular carcinoma, MRE, magnetic resonance elastography, MRI, magnetic resonance imaging, SMART, specific, measurable, achievable, relevant, timely, Disease burden, BARIATRIC SURGERY, Hepatology, SMART, business.industry, SERUM ALANINE AMINOTRANSFERASE, non-alcoholic fatty liver disease, PHYSICAL-ACTIVITY, alcohol-related or alcoholic liver disease, EASD, European Association for the Study of Diabete, EASO, ALD, general practitioner, relevant, T1D, business
وصف الملف: ELETTRONICO
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المؤلفون: Lucia Parlati, Catherine Postic, Marion Régnier, Hervé Guillou
المساهمون: LESUR, Hélène, Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance - - HepAdialogue2017 - ANR-17-CE14-0015 - AAPG2017 - VALID, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Catholique de Louvain = Catholic University of Louvain (UCL), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Lucia Parlati and Catherine Postic received funding from the French association for the study of the liver (AFEF). Catherine Postic and Herve Guillou received funding from the Agence Nationale de la Recherche (ANR-17-CE14-0015Hepadialogue)., ANR-17-CE14-0015,HepAdialogue,Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance(2017), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)
المصدر: JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩مصطلحات موضوعية: HFD, high-fat diet, SREBP-1c, [SDV]Life Sciences [q-bio], Disease, Review, ACC, acetyl-CoA carboxylase, ASK1, apoptosis signal-regulating kinase 1, Chronic liver disease, Bioinformatics, ChREBP, carbohydrate responsive element–binding protein, PPARα, NEFA, TNF-α, tumour necrosis factor-α, 0302 clinical medicine, Fibrosis, Immunology and Allergy, Medicine, IL-, interleukin, VLDL, very low-density lipoprotein, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, NEFA, non-esterified fatty acid, Fatty liver, Gastroenterology, NASH, lipotoxicity, FAS, fatty acid synthase, animal models, 3. Good health, [SDV] Life Sciences [q-bio], PY, persons/years, Lipotoxicity, FXR, Saturated fatty acid, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, LXR, CAP, controlled attenuation parameter, HSL, hormone-sensitive lipase, HSC, hepatic stellate cells, GGT, gamma glutamyltransferase, NAFLD, non-alcoholic fatty liver disease, ChREBP, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, TCA, tricarboxylic acid, Phf2, histone demethylase plant homeodomain finger 2, digestive system, 03 medical and health sciences, glucotoxicity, FXR, farnesoid X receptor, NAFLD, FFA, free fatty acid, Internal Medicine, RCT, randomised controlled trial, Liver X receptor, PPARa, 030304 developmental biology, FGF21, fibroblast growth factor-21, MCD, methionine- and choline-deficient, HVPG, hepatic venous pressure gradient, Hepatology, business.industry, PUFAs, polyunsaturated fatty acids, nutritional and metabolic diseases, TLR4, Toll-like receptor 4, SCD1, stearoyl-CoA desaturase-1, medicine.disease, digestive system diseases, PPARα, peroxisome proliferator-activated receptor-α, SREBP-1c, sterol regulatory element–binding protein-1c, Steatosis, LXR, liver X receptor, business, HCC, hepatocellular carcinoma, MUFA, monounsaturated fatty acids, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
وصف الملف: application/pdf
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المؤلفون: Spatz, Madeleine, Ciocan, Dragos, Merlen, Gregory, Rainteau, Dominique, Humbert, Lydie, Gomes-Rochette, Neuza, Hugot, Cindy, Trainel, Nicolas, Mercier-Nomé, Françoise, Domenichini, Séverine, Puchois, Virginie, Wrzosek, Laura, Ferrere, Gladys, Tordjmann, Thierry, Perlemuter, Gabriel, Cassard, Anne-Marie
المساهمون: Inflammation, microbiome, immunosurveillance (MI2), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Physiopathologie et traitement des maladies du foie, Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Laboratoire des biomolécules (LBM UMR 7203), Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Département de Chimie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Chimie Moléculaire de Paris Centre (FR 2769), Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Plateforme de métabolomique, Direction de la recherche [Gustave Roussy], Institut Gustave Roussy (IGR)-Institut Gustave Roussy (IGR), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100230-(2021)
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100230. ⟨10.1016/j.jhepr.2021.100230⟩
JHEP Reportsمصطلحات موضوعية: ALT, Gut-liver axis, mMMP9, matrix metallopeptidase 9, Alc, alcohol, TNF, tumour necrosis factor, TBA, UDCA, tumour necrosis factor, MCA, muricholic acid, Col1a1, collagen type-I alpha-1 chain, Kupffer cells, LCA, lithocholic acid, DCA, triglycerides, PCA, WT, alcohol, LCA, PICRUSt, TG, triglycerides, alpha-SMA, alpha-smooth muscle actin, cholic acid, Col1a1, alpha-SMA, FXR, deoxycholic acid, total bile acids, BHI, linear discriminative analysis, PICRUSt, phylogenetic investigation of communities by reconstruction of unobserved states, LDA, collagen type-I alpha-1 chain, BA, UDCA, ursodeoxycholic acid, FXR, farnesoid X receptor, OTU, operational taxonomic unit, C57C57, CC motif chemokine ligands, bile acids, operational taxonomic unit, ALD, alcohol-related liver diseases, CCL, CC motif chemokine ligands, C57C57, conventional mice transplanted with their own IM, nuclear factor-kappa B, CCL, IM, muricholic acid, RIN, MO, monocytes/macrophages, WT, wild-type, RNA integrity number, IM, intestinal microbiota, DCA, deoxycholic acid, false-discovery rate, brain heart infusion, CDCA, Microbiome, WT mice transplanted with the IM of TGR5-KO mice, C57, conventional mice, farnesoid X receptor, intestinal microbiota, TIMP1, transforming growth factor, OTU, principal component analysis, [SDV]Life Sciences [q-bio], TNF, knockout, alpha-smooth muscle actin, LEfsE, LDA effect size, TIMP1, tissue inhibitor of metalloproteinase 1, PCoA, principal coordinate analysis, C57, tissue inhibitor of metalloproteinase 1, TBA, total bile acids, TGF, transforming growth factor, CA, cholic acid, CA, KC, KO, LEfsE, TGF, ursodeoxycholic acid, lithocholic acid, LDA effect size, BA, bile acids, WTKO, WT mice transplanted with the IM of TGR5-KO mice, monocytes/macrophages, BHI, brain heart infusion, chenodeoxycholic acid, TG, Research Article, RIN, RNA integrity number, LDA, linear discriminative analysis, alanine aminotransferase, Bile acid, conventional mice, principal coordinate analysis, NFkB, FDR, CDCA, chenodeoxycholic acid, ALT, alanine aminotransferase, PCoA, conventional mice transplanted with their own IM, lcsh:RC799-869, KC, Kupffer cells, NFkB, nuclear factor-kappa B, mMMP9, wild-type, Inflammation, PCA, principal component analysis, KO, knockout, MCA, alcohol-related liver diseases, FDR, false-discovery rate, Alcoholic liver disease, Alc, MO, WTKO, ALD, matrix metallopeptidase 9, Dysbiosis, lcsh:Diseases of the digestive system. Gastroenterology, phylogenetic investigation of communities by reconstruction of unobserved states
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المؤلفون: Grzych, Guillaume, Chavez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothee, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Helene, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Rejane, Francque, Sven, Pattou, Francois, Haas, Joel T., Tailleux, Anne, Staels, Bart
المساهمون: Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Recherche translationnelle sur le diabète - U 1190 (RTD), University of Antwerp (UA), Antwerp University Hospital [Edegem] (UZA), ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), European Project: 32591,HEPADIP, European Project: 305707,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,RESOLVE(2013), Derudas, Marie-Hélène, PreciNASH - - PreciNASH2016 - ANR-16-RHUS-0006 - RHUS - VALID, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID, Hepatic and adipose tissue and functions in the metabolic syndrome - HEPADIP - 32591 - OLD, A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities, hypertriglyceridemia and low HDL-cholesterol - RESOLVE - - EC:FP7:HEALTH2013-01-01 - 2017-12-31 - 305707 - VALID, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille
المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)مصطلحات موضوعية: GHDCA, glycolithocholic acid, taurohyodeoxycholic acid, OGTT, oral glucose tolerance test, GUDCA, glycoursodeoxycholic acid, TCDCA, FXR, farnesoid-X-receptor, UDCA, ADA, American Diabetes Association, IR, insulin resistance, GCA, glycocholic acid, THDCA, taurohyodeoxycholic acid, HCA, T2D, LCA, lithocholic acid, HCA, hyocholic acid, DCA, TCDCA, taurochenodeoxycholic acid, GCDCA, glycochenodeoxycholic acid, LCA, NASH, GCDCA, GHCA, glycohyocholic acid, TCA, cholic acid, [SDV] Life Sciences [q-bio], FPG, glycoursodeoxycholic acid, FXR, deoxycholic acid, glycocholic acid, non-alcoholic steatohepatitis, TDCA, taurodeoxycholic acid, HbA1c, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, Translational study, oral glucose tolerance test, digestive system, BA, UDCA, ursodeoxycholic acid, HDCA, glycochenodeoxycholic acid, TUDCA, tauroursodeoxycholic acid, NAFLD, OGTT, taurochenodeoxycholic acid, NAFL, non-alcoholic fatty liver, GCA, FPG, fasting plasma glycaemia, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, C4, bile acids, glycodeoxycholic acid, nutritional and metabolic diseases, HOMA2, homeostatic model assessment 2, hyocholic acid, digestive system diseases, farnesoid-X-receptor, DCA, deoxycholic acid, GUDCA, IR, TLCA, taurolithocholic acid, American Diabetes Association, CDCA, Human medicine, ABOS, Biological Atlas of Severe Obesity, HDCA, hyodeoxycholic acid, [SDV]Life Sciences [q-bio], HOMA2, taurodeoxycholic acid, taurolithocholic acid, C4, 7alpha-hydroxy-4-cholesten-3-one, insulin resistance, Biological Atlas of Severe Obesity, taurohyocholic acid, MAFLD, metabolic associated fatty liver disease, CA, cholic acid, CA, THCA, GHDCA, glycohyodeoxycholic acid, Diabetes, TLCA, glycohyocholic acid, ursodeoxycholic acid, TUDCA, TDCA, fasting plasma glycaemia, lithocholic acid, NAFL, BA, bile acids, chenodeoxycholic acid, non-alcoholic fatty liver, type 2 diabetes, ABOS, Research Article, NAFLD, non-alcoholic fatty liver disease, TCA, taurocholic acid, MAFLD, taurocholic acid, CDCA, chenodeoxycholic acid, metabolic associated fatty liver disease, glycated haemoglobin, homeostatic model assessment 2, Obesity, lcsh:RC799-869, tauroursodeoxycholic acid, 7alpha-hydroxy-4-cholesten-3-one, non-alcoholic fatty liver disease, THDCA, hyodeoxycholic acid, ADA, GDCA, lcsh:Diseases of the digestive system. Gastroenterology, HbA1c, glycated haemoglobin, GHCA, glycohyodeoxycholic acid, THCA, taurohyocholic acid, GLCA
وصف الملف: application/pdf
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