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المؤلفون: Yi-Chao Zheng, Hong-Min Liu, Ouwen Li, Jun-Wei Wang, Zhenhe Suo, Fengyu Qi, Wen-Ting Kang, Pengxing He, Zhi-Ru Wang, Yinghua You
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)مصطلحات موضوعية: USP18, ubiquitin specific peptidase 18, medicine.medical_treatment, RIPA, radioimmunoprecipitation, PTMs, post-translational modifications, WB, Western blotting, 0302 clinical medicine, General Pharmacology, Toxicology and Pharmaceutics, HDN, well differentiated matched adjacent normal tissues, 0303 health sciences, PDN, poor differentiated matched adjacent normal tissues, biology, USP7, ubiquitin-specific processing protease 7, HDT, well differentiated tumor tissues, TCR, T cell receptor, Melanoma, DUB, deubiquitinating enzymes, PDT, poor differentiated tumor tissues, medicine.anatomical_structure, PBMC, peripheral blood mononuclear cells, 030220 oncology & carcinogenesis, GC, gastric cancer, Original Article, Epigenetics, USP22, ubiquitin specific peptidase 22, Immunotherapy, PD-L1, T cell, TCGA, the Cancer Genome Atlas, Cancer biology, irAEs, immune-related adverse effects, H2O2, hydrogen peroxidase, TILs, tumor-infiltrating T cells, PD-1, programmed cell death protein 1, 03 medical and health sciences, Immune system, PBS, phosphate buffer saline, Downregulation and upregulation, CHX, cycloheximide, medicine, HAUSP, herpes virus-associated ubiquitin-specific protease, EBNA1, Epstein–Barr nuclear antigen 1, 030304 developmental biology, Bladder cancer, ICP0, infected cell protein 0, business.industry, qRT-PCR, quantitative real time polymerase chain reaction, lcsh:RM1-950, Ubiquitination, GEPIA, Gene-Expression Profiling Interactive Analysis, medicine.disease, BCA, bicinchoninic acid, MDM2, murine double minute-2, USP38, ubiquitin specific peptidase 38, FDA, U.S. Food and Drug Administration, PD-L1, programmed death ligand-1, lcsh:Therapeutics. Pharmacology, FOXO4, forkhead box O4, USP9X, ubiquitin specific peptidase 9 X-linked, Cancer cell, biology.protein, Cancer research, USP7, IL-2, interleukin 2, CSN5, COP9 signalosome 5, business, Gastric cancer, Immunosuppression
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المؤلفون: Gustavo M. Silva, Nathan A. Snyder
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: translation, Ubiquitin C-Terminal Hydrolase, CYLD, conserved cylindromatosis, SUMO, small ubiquitin-like modifier, Biochemistry, MJD, Machado–Josephin domain, Deubiquitinating enzyme, TRAF6, tumor necrosis factor (TNF) receptor associated factor 6, RTU, redox control of translation by ubiquitin, USP, ubiquitin-specific protease, Ubiquitin, oxidative stress, Homeostasis, deubiquitination, BER, base excision repair, TNF, tumor necrosis factor, biology, Deubiquitinating Enzymes, Chemistry, OTU, ovarian tumor domain, Cell biology, AMSH, associated molecule with the SH3 domain of STAM, Mdm2, Polβ, DNA polymerase beta, Ubp, ubiquitin-binding protein, Oxidation-Reduction, Deubiquitination, Signal Transduction, TRAF2, tumor necrosis factor (TNF) receptor associated factor 2, PCNA, proliferating cell nuclear antigen, OTUB, varian tumor deubiquitinase, ubiquitin aldehyde binding, DUB, A20, tumor necrosis factor alpha–induced protein 3, MIC-CAP, microcephaly-capillary malformation, ROS, reactive oxygen species, ESCRT, endosomal sorting complexes required for transport, MDM2, Mouse double minute 2, ubiquitin, TGF-β, transforming growth factor beta, Endopeptidases, ATXN, ataxin, Integrated stress response, UPS, ubiquitin-proteasome system, Animals, Humans, redox signaling, Molecular Biology, enzymatic regulation, ISR, integrated stress response, BAP1, BRCA1-associated protein 1, JBC Reviews, Ubiquitination, WDR48, WD repeat domain 48, Tumor Necrosis Factor alpha-Induced Protein 3, Cell Biology, RPN11, regulatory particle non-ATPase 11, EGFR, epidermal growth factor receptor, CK2, casein kinase 2, QC, quality control, MINDY, motif interacting with Ub-containing novel DUB, FOXO4, forkhead box O4, Proteasome, DTT, dithiothreitol, NLS, nuclear localization signal, UCH, ubiquitin C-terminal hydrolase, biology.protein, RQC, ribosome-associated quality control, PTM, posttranslational modification, UIM, ubiquitin interacting motif, OTUD, ovarian tumor deubiquitinase, Reactive Oxygen Species, Protein Processing, Post-Translational, DUB, deubiquitinating enzyme or deubiquitinase