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المؤلفون: Ole H. Petersen, Ciara M. Walsh, Robert D. Burgoyne, Lee P. Haynes, Alexei V. Tepikin, Michael Chvanov
المصدر: Biochemical Journal
مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, Orai1, ORAI1 Protein, PtdIns(3,4,5)P3, Inositol 1,4,5-Trisphosphate, Endoplasmic Reticulum, Phosphatidylinositols, Biochemistry, ICRAC, Ca2+ release-activated Ca2+ current, Wortmannin, Phosphatidylinositol 3-Kinases, RFP, red fluorescent protein, chemistry.chemical_compound, Adenosine Triphosphate, 0302 clinical medicine, (E)CFP, (enhanced) cyan fluorescent protein, SOC, store-operated Ca2+ channel, 1-Phosphatidylinositol 4-Kinase, Phosphoinositide-3 Kinase Inhibitors, GFP, green fluorescent protein, PtdIns(4,5)P2, 0303 health sciences, Microscopy, Confocal, storeoperated calcium entry (SOCE), EYFP, enhanced yellow fluorescent protein, Voltage-dependent calcium channel, ORAI1, Chemistry, HEK-293, human embryonic kidney, NA, numerical aperture, calcium signal, PI3K, phosphatidylinositol 3-kinase, STIM1, [Ca2+]i, intracellular free Ca2+ concentration, fluo-4/AM, fluo-4 acetoxymethyl ester, Store-operated calcium entry, Neoplasm Proteins, phosphoinositide, Cell biology, PI4K, phosphatidylinositol 4-kinase, Protein Transport, PM, plasma membrane, SOCE, store-operated Ca2+ entry, FKBP12, FK506-binding protein 12, Protein Binding, Research Article, Morpholines, stromal interaction molecule 1 (STIM1), PH, pleckstrin homology, Transfection, ER, endoplasmic reticulum, 03 medical and health sciences, PLC, phospholipase C, Humans, Stromal Interaction Molecule 1, Phosphatidylinositol, Molecular Biology, 030304 developmental biology, Endoplasmic reticulum, Cell Membrane, Membrane Proteins, Cell Biology, endoplasmic reticulum calcium, Androstadienes, Kinetics, Luminescent Proteins, Chromones, FRB, fragment of mammalian target of rapamycin that binds FKBP12, RFP–ptase-dom, type IV 5-phosphatase domain fused to an RFP tag, Calcium, STIM, stromal interaction molecule, Calcium Channels, 030217 neurology & neurosurgery, HeLa Cells
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المؤلفون: Lauren E. Mursch, Kathryn K. Bercury, Jungsoo Min, Jinxiang Dai, Wendy B. Macklin, Stacey E. Cifelli, Teresa L. Wood
المصدر: ASN Neuro, Vol 5 (2013)
ASN NEUROمصطلحات موضوعية: MBP, myelin basic protein, protor, protein observed with rictor, Cellular differentiation, HDAC, histone deacetylase, Review Article, IGF-I, insulin-like growth factor 1, Nervous System, PDGF, platelet-derived growth factor, Myelin, C/EBP, CCAAT/enhancer-binding protein, PGC-1α, peroxisome-proliferator-activated receptor coactivator-1α, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, ID, inhibitor of DNA binding/differentiation, SREBP-1, sterol-regulatory-element-binding protein, Transcriptional regulation, GalC, galactosyl cerebroside, S6K1/2, S6 kinase, 0303 health sciences, YY1, Yin Yang 1, General Neuroscience, TOR Serine-Threonine Kinases, mammalian target of rapamycin (mTOR), myelination, Gene Expression Regulation, Developmental, TCF4/TCF7L2, T cell factor 4, Cell Differentiation, AGC-type kinases, protein kinase A/protein kinase G/protein kinase C-family kinases, PLP, proteolipid protein, VEGF, vascular endothelial growth factor, S11, Cell biology, myelin, Oligodendroglia, medicine.anatomical_structure, IRS, insulin receptor substrate, FKBP12, FK506-binding protein 12, PI3K, phosphoinositide 3-kinase, GPR17, G-protein coupled receptor 17, Signal Transduction, PTEN, phosphatase and tensin homologue deleted on chromosome 10, mTOR, mammalian target of rapamycin, Biology, PKC-α, protein kinase C-α, CNS, central nervous system, S2, bHLH, basic helix–loop–helix, lcsh:RC321-571, 03 medical and health sciences, SGK1, serum- and glucocorticoid-induced protein kinase 1, IGF-IR, IGF type 1 receptor, 4EBP1-3, eIF4E-binding proteins, medicine, Animals, Humans, PDK2, phosphoinositide-dependent kinase 2, Transcription factor, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, PI3K/AKT/mTOR pathway, 030304 developmental biology, HAT, histone acetyl transferase, RPTOR, Oligodendrocyte differentiation, OPC, oligodendrocyte progenitor cell, BMP, bone morphogenetic protein, PPARγ, peroxisome-proliferator-activated-receptor γ, mTOR complex 2 (mTORC2), HIF1α, hypoxia-induced factor 1α, Oligodendrocyte, siRNA, small interfering RNA, mSIN1, mammalian stress-activated protein kinase interacting protein 1, PNS, peripheral nervous system, Neurology (clinical), PRAS40, praline-rich Akt substrate of 40 kDa, mTOR complex 1 (mTORC1), TSC, tuberous sclerosis complex, Neuroscience, 030217 neurology & neurosurgery, oligodendrocyte, MAPK, mitogen-activated protein kinase, mTORC2, rictor-mTOR complex, Rheb, Ras homologue enriched in brain, mTORC1, raptor-mTOR complex