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1
المؤلفون: Hong-Min Liu, Ya-Hong Wu, Yihui Song, Min Zhao, Bin Yu
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 750-762 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: PMSF, phenylmethanesulfonyl fluoride, LS, LEOPARD syndrome, Mutant, IC50, half maximal inhibitory concentration, Protein tyrosine phosphatase, HTS, high-throughput screening, chemistry.chemical_compound, 0302 clinical medicine, DiFMUP, 6,8-difluoro-4-methylumbelliferyl phosphate, General Pharmacology, Toxicology and Pharmaceutics, AML, acute myelogenous leukemia, Tm, melting temperature, 0303 health sciences, LB, lysogeny broth, SDS-PAGE, sodium dodecyl sulphate polyacyrlamide gel electrophoresis, High-throughput screening, R2, coefficient of determination, S/B, signal over background, STAT, signal transducer and activator of transcription, SHP2, Src homology phosphotyrosyl phosphatase 2, Biochemistry, 030220 oncology & carcinogenesis, Original Article, BTLA, B and T lymphocyte attenuator, PTP, protein tyrosine phosphatase, SH2, Src homology 2, Proto-oncogene tyrosine-protein kinase Src, Thermal shift assay, Allosteric regulation, Phosphatase, JAK, janus kinase, AKT, protein kinase B, SHP2-WT, wild type Src homology phosphotyrosyl phosphatase 2, SHP2-PTP, protein tyrosine phosphatase domain of Src homology phosphotyrosyl phosphatase 2, 03 medical and health sciences, PI3K, phosphatidylinositol 3 kinase, NS, Noonan syndrome, RAS, rat sarcoma, FI, fluorescence intensity, NPC, no protein control, 030304 developmental biology, ΔTm, melting temperature change, DiFMU, 6,8-difluoro-4-methylumbelliferyl hydroxid, ALK, anaplastic lymphoma kinase, lcsh:RM1-950, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, MEK, extracellular regulated protein kinase kinases, JMML, juvenile myelomonocytic leukaemia, Enzyme assay, PD-1, programmed death 1, p-IRS1, phosphorylated insulin receptor substrate 1, Bis-tris, bis-(2-hydroxyethyl)amino-tris(hydroxymethyl)methane, OD, optical density, lcsh:Therapeutics. Pharmacology, chemistry, DTT, dithiothreitol, SHP2, Allosteric inhibitors, Bioisostere, LOC, ligand only control, SD, standard deviation, MAPK, mitogen-activated protein kinase
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2
المؤلفون: Pengcheng Zhang, Junyang Wang, Yaping Li, Yiran Liu, Yihui Zhai, Wei Ran, Xiyue Zhao, Yaping Ding, Ying Cai, Guanru Wang, Xiaoyu Liu
المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 1050-1060 (2019)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Tmax, time to reach highest fluorescence intensity, BUN, blood urea nitrogen, Hepatocellular carcinoma, DL, drug loading, medicine.medical_treatment, FI range, fluorescence intensity range, C16-N/DiR, DiR-labeled C16-N hydrogel, DSPE-PEG/T, drug-loaded DSPE-PEG micelles, EE, encapsulation efficiency, Pharmacology, chemistry.chemical_compound, 0302 clinical medicine, AST, aspartate transaminase, CKS2, cyclin kinase subunit-2, LC–MS, liquid chromatography–mass spectrometry, General Pharmacology, Toxicology and Pharmaceutics, Cytotoxicity, CD, circular dichroism, ANOVA, analysis of variance, 0303 health sciences, C16-N/DiI, DiI-labeled C16-N, Self-assembly, AURKA, aurora A kinase, AUC0–13, areas under the curve, 030220 oncology & carcinogenesis, Growth inhibition, Original article, CRE, creatinine, Intraperitoneal injection, TACE, transarterial chemoembolization, TIR, tumor inhibition rate, 03 medical and health sciences, Therapeutic index, FBS, fetal bovine serum, GEMOX, gemcitabine and oxaliplatin, d-Luciferin, (S)-4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium, DSPE-PEG, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino (polyethylene glycol)-2000], medicine, Peptide amphiphile, TEM, transmission electron microscopy, FI, fluorescence intensity, 030304 developmental biology, Chemotherapy, Triptolide, business.industry, Bel-7402/Luc, luciferase transfected human HCC cell line Bel-7402, lcsh:RM1-950, C16-N/T, triptolide-loaded peptide amphiphile-based hydrogel, medicine.disease, digestive system diseases, CAS, Chinese Academy of Sciences, DSPE-PEG/DiR, DiR-labeled DSPE-PEG micelle, HFIP, 1,1,1,3,3,3-hexafluoro-2-propanol, Hydrogel, C16-N, C16-GNNQQNYKD-OH, lcsh:Therapeutics. Pharmacology, DSPE-PEG/DiI, DiI-labeled DSPE-PEG, chemistry, ATL, alanine transaminase, Akt, protein kinase B, HPLC, high-performance liquid chromatography, H&E, hematoxylin and eosin, OB glue, EPIGLUs, RFI, relative fluorescence intensity, business
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3
المؤلفون: Oliver Lung, Tara Furukawa-Stoffer, Cody Buchanan, Niroshan Thanthrige-Don, Dale L. Godson, Tomy Joseph, John S. Gilleard, Aruna Ambagala, Trevor W. Alexander
المصدر: Journal of Virological Methods
مصطلحات موضوعية: 0301 basic medicine, BED, bovine enteric diseases, Time Factors, Microarray, Gastrointestinal Diseases, BCoV, bovine corona virus, DENV, dengue virus, Lt, heat labile toxin, ETEC, enterotoxigenicE. coli, law.invention, 0403 veterinary science, BRSV, bovine respiratory syncytial virus, PCR, polymerase chain reaction, law, EPEC, enteropathogenic E. coli, Multiplex, EHEC, enterohemorrhagic E. coli, Pasteurella multocida, Respiratory Tract Infections, Polymerase chain reaction, BToV, bovine torovirus, biology, LNA, lock nucleic acid, lktA, leukotoxin-A, stx-1, shiga-like toxin 1, Bovine enteric diseases, 04 agricultural and veterinary sciences, E.coli, Escherichia coli, Molecular Diagnostic Techniques, Salmonella enterica, Viruses, BoHV-1, Bovine herpesvirus 1, Veterinary Medicine, Bovine respiratory disease complex, 040301 veterinary sciences, 030106 microbiology, Cattle Diseases, BPI-3, bovine parainfluenza virus 3, Sensitivity and Specificity, Article, 03 medical and health sciences, RT-PCR, reverse transcription polymerase chain reaction, Virology, Multiplex polymerase chain reaction, Animals, 5′UTR, 5′ untranslated region, FI, fluorescence intensity, Bovine coronavirus, LOD, limit of detection, Bacteria, BRoV, bovine rotavirus, DNA microarray, Multiplex PCR, Microarray Analysis, biology.organism_classification, Bovine Respiratory Disease Complex, Coccidia, BRDC, bovine respiratory disease complex, LSB, low salt buffer, Cattle, BVDV, bovine viral diarrhea virus, nmaA, UDP-N-acetyle-D-glucosamine-2-epimerase gene, tbpB, transferring-binding protein B gene, Multiplex Polymerase Chain Reaction, GI, Geninfo identifier, NTC, no-template control
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4
المؤلفون: Yi-Hsuan Pan, Chonggang Yuan, Jiyan Ma, Xiangyi Zhang, Guohua Yu, Ji Ma, Chenhua Pan, Ying Chen
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: PrPSc Proteins, animal diseases, medicine.medical_treatment, prion disease, Mutant, Fi, fluorescence intensity, POPG, POPG, 1-palmitoyl-2-oleoylphosphatidylglycerol, Scrapie, NPR, N-terminal polybasic region of PrP, Biochemistry, Cofactor, Cell Line, Prion Diseases, law.invention, prion, Mice, chemistry.chemical_compound, conformational change, N-terminal polybasic region, law, PK, proteinase K, medicine, Animals, PrPC Proteins, Molecular Biology, chemistry.chemical_classification, PrP, prion protein, Methionine, Protease, biology, Chemistry, Brain, sPMCA, serial protein misfolding cyclic amplification, Cell Biology, Proteinase K, convertibility, nervous system diseases, Amino acid, Mutation, biology.protein, Recombinant DNA, recPrP, recombinant PrP, Rabbits, DPI, days post inoculation, Research Article
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5
المؤلفون: Mayuko Morita, Yuji Naito, Toshikazu Yoshikawa, Etsuo Niki
المصدر: Redox Biology
Redox Biology, Vol 8, Iss C, Pp 127-135 (2016)مصطلحات موضوعية: Male, 0301 basic medicine, Antioxidant, medicine.medical_treatment, SIN-1, 3-morpholinosydnonimine, Lipoxygenase, Clinical Biochemistry, Hypochlorite, Photochemistry, Biochemistry, Peroxynitrite, Antioxidants, Lipid peroxidation, Mice, chemistry.chemical_compound, NDGA, nordihydroguaiaretic acid, lcsh:QH301-705.5, LOX, lipoxygenase, Dipheyl-1-pyrenylphosphine (DPPP), lcsh:R5-920, Pyrenes, biology, AAPH, 2,2′-azobis(2-amidinopropane) dihydrochloride, Oxidants, Lipids, Lipid oxidation, Peroxides, lipids (amino acids, peptides, and proteins), lcsh:Medicine (General), Oxidation-Reduction, Research Paper, Hypochlorous acid, 03 medical and health sciences, Organophosphorus Compounds, Peroxynitrous Acid, medicine, Animals, FI, fluorescence intensity, Organic Chemistry, DPPP, diphenyl-1-pyrenylphosphine, Hypochlorous Acid, Peroxynitrous acid, 030104 developmental biology, lcsh:Biology (General), chemistry, MeO-AMVN, 2,2′-azobis-(4-methoxy-2,4-dimethyllvaleronitrile), biology.protein, Lipid Peroxidation, Biomarkers
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6
المؤلفون: Ruifu Yang, Dongsheng Zhou, Long Qin, Zeliang Chen, Zongmin Du, Bei Li, Zhaobiao Guo, Yajun Song, Yanping Han, Jianshan Zhang
المصدر: Microbes and Infection
مصطلحات موضوعية: Male, Pore Forming Cytotoxic Proteins, Proteomics, Virulence Factors, Yersinia pestis, Immunology, Mutant, Protein Array Analysis, PBS, phosphate-buffered saline, Virulence, Microbiology, Article, T3SS, Type III secretion system, QSM, QS double mutant, Bacterial Proteins, Animals, Virulence-associated protein, LCRS, low calcium response stimulon, YOP, Yersinia outer protein, LcrV, FI, fluorescence intensity, SARS-CoV, severe acute respiratory syndrome-associated coronavirus, Antigens, Bacterial, biology, Wild type, Quorum Sensing, TMB, tetramethylbenzidine, HRP, horseradish peroxidase, ELISA, enzyme-linked immunosorbent assay, biology.organism_classification, QSW, QS wild type, Quorum sensing mutant, Quorum sensing, Infectious Diseases, Mutation, QS, quorum sensing, Protein microarray, Rabbits, Antibody profiling
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7
المؤلفون: Maofeng Qiu, Dongsheng Zhou, Xin Pang, Yong Zhang, Bingyin Si, Junhui Zhai, Xiaoyi Wang, Jian Wang, Zongmin Du, Runsheng Chen, Hongxia Wang, Yuling Shi, Erhei Dai, Jin Wang, Ling Yang, Bing Sun, Ruifu Yang, Ying Liu, Zhaobiao Guo, Jingxiang Li, Rongqiao He, Yajun Song, Linhai Li, Zeliang Chen
المصدر: Microbes and Infection
مصطلحات موضوعية: Recombinant protein, SARS coronavirus, E protein, envelope glycoprotein, Immunology, Protein microarray, Biology, medicine.disease_cause, Antibodies, Viral, Neutralizing antibodies, Microbiology, Virus, Article, Antibodies, S protein, spike glycoprotein, Viral Proteins, Nidovirales, Neutralization Tests, TCID50, 50% tissue culture infective doses, medicine, Coronaviridae, Animals, Humans, M protein, membrane protein, Neutralizing antibody, skin and connective tissue diseases, FI, fluorescence intensity, Coronavirus, Antiserum, SARS-CoV, the SARS coronavirus, fungi, biology.organism_classification, Virology, N protein, nucleocapsid protein, body regions, Infectious Diseases, Severe acute respiratory syndrome-related coronavirus, Immunoglobulin G, Humoral immunity, biology.protein, Rabbits, Antibody
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8Academic Journal
المؤلفون: Kesavan, Jana, Doherty, Robert W.
المساهمون: EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
المصدر: DTIC AND NTIS
مصطلحات موضوعية: Physical Chemistry, Atomic and Molecular Physics and Spectroscopy, AEROSOLS, FLUORESCENT DYES, TRACER STUDIES, TEST AND EVALUATION, PARTICLE SIZE, FLUORESCENCE, EXCITATION, EMISSION SPECTRA, GLASS FIBERS, SAMPLING, FILTERS, FLUOROMETERS, LABELED SUBSTANCES, FLUORESCEIN, FI(FLUORESCENCE INTENSITY), PE62238A
وصف الملف: text/html
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9
المؤلفون: S. J. Gunn, Jacob Hooper, Thomas Lanyon-Hogg, Alison Baker, Stuart L. Warriner
المصدر: Febs Letters
مصطلحات موضوعية: Peroxisome-Targeting Signal 1 Receptor, Arabidopsis thaliana, Biophysics, Arabidopsis, Receptors, Cytoplasmic and Nuclear, Plasma protein binding, macromolecular substances, PMP, peroxisomal membrane protein, Peroxisome, PEX14, Biochemistry, environment and public health, Article, law.invention, Structural Biology, law, Genetics, Receptor, Molecular Biology, Peroxisomal targeting signal, FI, fluorescence intensity, Peroxisomal Targeting Signal 2 Receptor, biology, Thiolase, Arabidopsis Proteins, FA, fluorescence anisotropy, Membrane Proteins, HRP, horseradish peroxidase, Cell Biology, PEX7, biology.organism_classification, PEX5, Cell biology, Transport protein, PTS, peroxisomal targeting signal, Repressor Proteins, Kinetics, Protein Transport, Membrane protein, PEX, peroxisome biogenesis, Recombinant DNA, PTS2, PTS1, Protein Binding, Cargo unloading
وصف الملف: application/pdf
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10Evaluation of hepatic perfusion in the liver graft using fluorescence imaging with indocyanine green
المؤلفون: Junichi Kaneko, Yoshihiro Sakamoto, Junichi Arita, Kiyoshi Hasegawa, Takeaki Ishizawa, Nobuhisa Akamatsu, Yoshikuni Kawaguchi, Norihiro Kokudo
المصدر: International Journal of Surgery Case Reports
مصطلحات موضوعية: Fluorescence imaging technique, medicine.medical_specialty, Fluorescence-lifetime imaging microscopy, Graft dysfunction, Pathology, genetic structures, medicine.medical_treatment, ICG, indocyanine green, Liver transplantation, LT, liver transplantation, behavioral disciplines and activities, Article, D-IOUS, Doppler intraoperative ultrasonography, chemistry.chemical_compound, mental disorders, Medicine, FI, fluorescence intensity, business.industry, PVT, portal vein thrombosis, food and beverages, medicine.disease, Portal vein thrombosis, eye diseases, Indocyanine green, Liver graft, Fluorescence intensity, Living-donor liver transplantation, surgical procedures, operative, chemistry, Surgery, Radiology, business, human activities, Perfusion
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11Electronic Resource
المؤلفون: EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD, Kesavan, Jana, Doherty, Robert W.
المصدر: DTIC AND NTIS
مصطلحات الفهرس: Physical Chemistry, Atomic and Molecular Physics and Spectroscopy, AEROSOLS, FLUORESCENT DYES, TRACER STUDIES, TEST AND EVALUATION, PARTICLE SIZE, FLUORESCENCE, EXCITATION, EMISSION SPECTRA, GLASS FIBERS, SAMPLING, FILTERS, FLUOROMETERS, LABELED SUBSTANCES., FLUORESCEIN, FI(FLUORESCENCE INTENSITY), PE62238A, Text