-
1
المؤلفون: Heidi L. Weiss, Stephanie A. Rock, Tianyan Gao, Chi Wang, Jing Li, B. Mark Evers, Yuanyuan Wu, Kai Jiang, Yajuan Liu, Jianhang Jia
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 501-516 (2022)مصطلحات موضوعية: PPARδ, peroxisome proliferator-activated receptor δ, Enteroendocrine cell, RC799-869, Lgr5, Leucine-rich repeat-containing G-protein coupled receptor 5, Mice, chemistry.chemical_compound, GLP-2, glucagon-like peptide 2, GSEA, gene set enrichment analysis, Intestinal mucosa, FACS, fluorescence-activated cell sorting, Intestine, Small, Gene expression, Neurotensin, Original Research, Stem Cells, EdU, 5-ethynyl-2′-deoxyuridine, Gastroenterology, Wnt signaling pathway, LGR5, p-ERK1/2, phosphorylated ERK1/2, Diseases of the digestive system. Gastroenterology, EGFP, enhanced green fluorescent protein, mRNA, messenger RNA, Cell biology, Intestinal Stem Cells, medicine.anatomical_structure, CRC, colorectal cancer, ISC, intestinal stem cell, EE, enteroendocrine, qPCR, quantitative polymerase chain reaction, Drosophila, Stem cell, LRP6, low density lipoprotein receptor-related protein 6, GSK3β, glycogen synthase kinase 3 beta, p-GSK3β, phosphorylated GSK3β, NTR1, neurotensin receptor 1, PBS, phosphate-buffered saline, Biology, ERK, extracellular-signal-regulated kinase, NT, neurotensin, digestive system, cDNA, complementary DNA, medicine, Animals, p-AKT, phosphorylated AKT, TK, tachykinin, Cell Proliferation, LED, low-energy diet, Hepatology, fungi, Nutrients, Small intestine, Diet, chemistry, FAO, fatty acid oxidation, MAPK, mitogen-activated protein kinase
-
2
المؤلفون: David A. Frank, Isidora Tošić
المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)مصطلحات موضوعية: Cancer Research, p53, tumor protein 53, MEF2D, Myocyte Enhancer Factor 2D, FASN, fatty acid synthase, OXPHOS, oxidative phosphorylation, ERH, enhancer of rudimentary homolog, PDGF, platelet-derived growth factor, PFK, phosphofructokinase, CREB, cyclic AMP response element-binding protein, HDL-C, high-density lipoprotein cholesterol, chemistry.chemical_compound, PC, phosphatidylcholine, GRIM-19, gene associated with retinoid-IFN-induced mortality, Neoplasms, Transcriptional regulation, TGFβ, transforming growth factor beta, AML, acute myeloid leukemia, RC254-282, CDK, cyclin-dependent kinase, FABP6, fatty acid binding protein 6, BCL, B-cell lymphoma, CLL, chronic lymphocytic leukemia, Chemistry, LIF, leukemia inhibitory factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, VEGF, vascular endothelial growth factor, FBP1, fructose-bisphosphatase 1, GPI, glucose-6-phosphate isomerase, Cell biology, MMP, matrix metalloproteinase, STAT, signal transducer and activator of transcription, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, GP130, glycoprotein 130, Phosphorylation, NHL, non-Hodgkin's lymphoma, JAK, Janus kinase, Adenosine triphosphate, CNTF, ciliary neurotrophic factor, STAT3 Transcription Factor, ATP, adenosine triphosphate, TAG, triacylglycerol, Protein processing, Post-translational, PPARγ, peroxisome proliferator-activated receptor gamma, ETC, electron transport chain, TNFα, tumor necrosis factor alpha, RIME, rapid immunoprecipitation mass spectrometry of endogenous proteins, GLUT1, glucose transporter 1, PGK1, phosphoglycerate kinase, MPTP, mitochondrial permeability transition pore, Mediator, Review article, CML, chronic myeloid leukemia, HIF1α, hypoxia inducible factor 1α, PIAS, protein inhibitors of activated STATs, SOCS, suppressors of cytokine signaling, Animals, Humans, IFN, interferon, LDHA, lactate dehydrogenase A, Transcription factor, PKCδ, protein kinase C δ, TF, transcription factors, EGF, epidermal growth factor, SM, sphingomyelin, SREBP1, sterol regulatory element-binding protein 1, IAP, inhibitor of apoptosis, PTP, protein tyrosine phosphatases, Tyrosine phosphorylation, Lipid metabolism, BCSC, breast cancer stem cells, IL, interleukin, Metabolism, OSM, oncostatin M, Anaerobic glycolysis, NFκB, nuclear factor kappa B, TBK1, TANK-binding kinase 1, MCL, myeloid cell leukemia, LDL-C, low-density lipoprotein cholesterol, PBP, PPARγ binding protein, CPT1B, carnitine palmitoyltransferase 1B, FAO, fatty acid oxidation
-
3
المؤلفون: Bonnie Ky, Anja Karlstaedt, Matthew Barrett, Seth Thomas Gammons, Ray Hu
المصدر: JACC: Basic to Translational Science
مصطلحات موضوعية: medicine.medical_specialty, cardio-oncology, [18F]FDG, 2-deoxy-2-[fluorine-18]fluoro-D-glucose, PTM, post-translational modification, IGF, insulin-like growth factor, SGLT2, sodium glucose co-transporter 2, oncometabolism, 99mTc-MIBI, 99mtechnetium-sestamibi, FASN, fatty acid synthase, Cardiac metabolism, heart failure, IDH, isocitrate dehydrogenase, Cardiovascular care, Context (language use), Disease, CVD, cardiovascular disease, D2-HG, D-2-hydroxyglutarate, HF, heart failure, PET, positron emission tomography, GLS, glutaminase, TRF, time-restricted feeding, medicine, cancer, PI3K, insulin-activated phosphoinositide-3-kinase, Cancer biology, Cardio oncology, Intensive care medicine, α-KG, α-ketoglutarate, MCT1, monocarboxylate transporter 1, Cancer, MRS, magnetic resonance spectroscopy, medicine.disease, PDH, pyruvate dehydrogenase, State-of-the-Art Review, Cardiology and Cardiovascular Medicine, metabolism, FAO, fatty acid oxidation, Potential toxicity
-
4
المؤلفون: Tadahito Yasuda, Hideo Baba, Takatsugu Ishimoto
المصدر: Regenerative Therapy, Vol 17, Iss, Pp 8-12 (2021)
Regenerative Therapyمصطلحات موضوعية: 0301 basic medicine, Medicine (General), OXPHOS, oxidative phosphorylation, 0302 clinical medicine, Glycolysis, NRF2, nuclear factor erythroid 2–related factor 2, LSCs, leukemia stem cells, education.field_of_study, EVs, extracellular vesicles, mTORC1, mammalian target of rapamycin complex 1, ROS, GP6, glucose-6-phosphate, IncRNAs, long noncoding RNAs, Original Article, Stem cell, IMP2, insulin-like growth factor 2, EMT, epithelial–mesenchymal transition, ATP, adenosine triphosphate, Stromal cell, CSCs, cancer stem cells, Population, TCA, tricarboxylic acid, Biomedical Engineering, PPP, pentose phosphate pathway, FBP1, fructose-1,6-biphosphatase 1, GLUT1, glucose transporter 1, Oxidative phosphorylation, Biology, Stromal niche, Biomaterials, 03 medical and health sciences, ROS, reactive oxygen species, R5-920, Cancer stem cell, PDK1, pyruvate dehydrogenase kinase 1, medicine, education, HIF1a, hypoxia inducible factor 1a, TICs, tumor initiating stem-like cells, SOD2, superoxide dismutase 2, QH573-671, Cancer, medicine.disease, Mitochondrial OXPHOS, CD44v, CD44 variant isoform, Metabolic pathway, ALDH, aldehyde dehydrogenase, 030104 developmental biology, Cancer research, CSCs, HCC, hepatocellular carcinoma, Cytology, FAO, fatty acid oxidation, 030217 neurology & neurosurgery, Developmental Biology
-
5
المؤلفون: Andras Perl, Christian Geier
المصدر: Autoimmunity Reviews
مصطلحات موضوعية: ULK1, Unc-51 like autophagy activating kinase, p70S6K, P70-S6 kinase, DAMP, damage-associated molecular pattern, RA, rheumatoid arthritis, Autoimmunity, Review, Antiviral immunity, Raptor, regulatory-associated protein of mTOR, medicine.disease_cause, DEPTOR, DEP domain-containing mTOR-interacting protein, SLE, systemic lupus erythematosus, DC, dendritic cell, MOG, Myelin oligodendrocyte glycoprotein, Immunology and Allergy, Lupus Erythematosus, Systemic, ANA, antinuclear antibodies, COVID-19, coronavirus disease 2019, EAE, experimental autoimmune encephalomyelitis, TH, T helper cell, EBV, Epstein-Barr virus, TNF, tumor necrosis factor, biology, TCR, T cell receptor, TOR Serine-Threonine Kinases, mTOR, mechanistic target of rapamycin, Lc3b, microtubule-associated protein 1 light chain 3β, Rictor, rapamycin-insensitive companion of mTOR, CCR7, CC-chemokine receptor 7, Acquired immune system, medicine.anatomical_structure, 4E-BP2, eukaryotic translation initiation factor 4E-binding protein 2, mTORC, mTOR complex, G6PD, glucose-6-phosphate-dehydrogenase, mTOR, Lifespan extension, PRR5, Proline-rich protein 5, medicine.symptom, Rapa, rapamycin, Mechanistic target of rapamycin, PI3K, phosphoinositide 3-kinase, medicine.drug, IKK-β, inhibitor of nuclear factor kappa-B kinase subunit beta, TLR, Toll-like receptor, Rheb, ras homolog enriched in brain, T cell, Immunology, Longevity, SIN1, Stress-activated map kinase-interacting protein 1, Treg, regulatory T cell, Inflammation, ETV7, transcription factor ETV7, FKBP8, FKBP prolyl isomerase 8, Antiviral Agents, MSU, monosodium urate, PD-1, programmed cell death protein 1, Systemic lupus erythematosus, HHV-8, human herpesvirus-8, PRAS40, proline-rich Akt substrate of 40 kDa, medicine, Humans, eiF4E, Elongation initiation factor 4E, PI3K/AKT/mTOR pathway, Aged, Sirolimus, MHC, Major histocompatibility complex, Immune cell lineage specification, Innate immune system, IFN-γ, interferon gamma, business.industry, SARS-CoV-2, S1P1, sphingosine-1-phosphate receptor 1, COVID-19, iMCD, idiopathic multicentric Castleman disease, NAC, N-Acetylcysteine, AMPK, AMP-activated protein kinase, APC, antigen-presenting cell, KSHV, Kaposi's sarcoma-associated herpesvirus, 4E-BP1, eukaryotic translation initiation factor 4E-binding protein 1, biology.protein, business, mLST8, mammalian lethal with SEC13 protein 8, TSC, tuberous sclerosis complex, FAO, fatty acid oxidation
-
6
المصدر: JACC: Basic to Translational Science
مصطلحات موضوعية: MCT, monocrotaline, Hypochloremia, DCA, dicarboxylic fatty acid, MCT-V, monocrotaline-vehicle, TCA, tricarboxylic acid, GLUT1, glucose transporter 1, Mitochondrion, Pharmacology, PVR, pulmonary vascular resistance, AS160, 160 kDa substrate of the Akt serine/threonine kinase, Glycation, WNK, with no lysine kinase, pulmonary arterial hypertension, RV, right ventricle/ventricular, GLO2, glyoxalase 2, Medicine, PTM, post-translationally modify/modifications, Tau/τ, right ventricular relaxation time, Protein kinase A, UDP-GlcNAC, uridine diphosphate N-acetylglucosamine, GLUT4, glucose transporter 4, AMPK, adenosine monophosphate-activated protein kinase, business.industry, LV, left ventricle/ventricular, Glucose transporter, RVD, right ventricular dysfunction, lipotoxicity, medicine.disease, WNK1, Adenosine, mitochondria, PV, pressure-volume, RA, right atrial, Lipotoxicity, right ventricular dysfunction, GLO1, glyoxalase 1, Preclinical Research, PAH, pulmonary arterial hypertension, Cardiology and Cardiovascular Medicine, business, metabolism, with no lysine kinase 1, FAO, fatty acid oxidation, medicine.drug
-
7
المؤلفون: Jiancheng Zheng, Yibo Gan, XuTan, Ziwen Wang, Chi Zhang, Aihua Zhang, Huilan Wang, Min Luo, Fengying Liao, Ziyuan Zhou, Chunmeng Shi, Lei Long, Yawei Wang, Yu Wang, Zelin Chen, Peng Luo, Long Chen, Yu Huang, Zeyu Yang, Zhongyong Jiang, Xueru Li, Yunsheng Liu
المصدر: Redox Biology
Redox Biology, Vol 46, Iss, Pp 102082-(2021)مصطلحات موضوعية: Medicine (General), SDH, Succinate dehydrogenase, Succinate, QH301-705.5, Clinical Biochemistry, α-SMA, Alpha-smooth muscle actin, SDHA, Idiopathic pulmonary fibrosis, Bleomycin, Biochemistry, BALF, Bronchoalveolar Lavage Fluid, chemistry.chemical_compound, R5-920, Downregulation and upregulation, NIR, Near-infrared, Fibrosis, IR-780, medicine, Humans, FAO, Fatty acid oxidation, ECAR, Extracellular acidification rate, Biology (General), Myofibroblasts, Lung, SLC, Solute carrier family, biology, IPF, Idiopathic pulmonary fibrosis, TEM, Transmission electron microscopy, Succinate dehydrogenase, Organic Chemistry, Transdifferentiation, ECM, Excessive extracellular matrix, OATPs, Organic-anion-transporting polypeptide, respiratory system, Fibroblasts, medicine.disease, OCR, Oxygen consumption rate, respiratory tract diseases, medicine.anatomical_structure, chemistry, Pharmaceutical Preparations, Metabolic dysregulation, biology.protein, Cancer research, Research Paper
-
8
المؤلفون: Cory J. White, Michael J. Wolfgang, Jessica M. Ellis
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Central Nervous System, DHA, docosahexaenoic acid, AA, arachidonic acid, Biochemistry, PEtN, phosphoethanolamine, Substrate Specificity, chemistry.chemical_compound, PC, phosphatidylcholine, Mice, PFC, prefrontal cortex, Homeostasis, ANOVA, analysis of variance, Phospholipids, Chemistry, Fatty Acids, qRT-PCR, quantitative real-time polymerase chain reaction, Gene Expression Regulation, Developmental, HBSS, Hank’s buffered salt solution, Fasting, Lipidome, Cell biology, medicine.anatomical_structure, Docosahexaenoic acid, TRAP, translating ribosomal affinity purification, Ethanolamines, Phosphorus-Oxygen Lyases, Oxidation-Reduction, Astrocyte, Research Article, brain, Dietary lipid, Phospholipid, EtN, ethanolamine, liver, CNS, central nervous system, PE, phosphatidylethanolamine, 03 medical and health sciences, Membrane Lipids, astrocyte, Oxygen Consumption, Receptors, Glucocorticoid, lipid, eas, easily shocked, PUFA, polyunsaturated fatty acid, medicine, Animals, Molecular Biology, Glucocorticoids, Phosphatidylethanolamine, HSP, hereditary spastic paraplegia, KO, knockout, 030102 biochemistry & molecular biology, Brain morphometry, Cell Biology, Lipid Metabolism, Diet, 030104 developmental biology, phosphatidylethanolamine, Astrocytes, glucocorticoid, Etnppl, ethanolamine phosphate phospholyase, Ribosomes, FAO, fatty acid oxidation
-
9
المؤلفون: Jain Jeong, Yasuko Iwakiri
المصدر: Cellular and Molecular Gastroenterology and Hepatology
مصطلحات موضوعية: Nonalcoholic steatohepatitis, Oxidized LDL, VEGFC, LSEC, liver sinusoidal endothelial cell, MEDLINE, PBS, phosphate-buffered saline, AST, aspartate aminotransferase, HFHC, high fat, high cholesterol, Bioinformatics, VEGFC, vascular endothelial growth factor C, Permeability, OxLDL, oxidized low density lipoprotein, Text mining, Non-alcoholic Fatty Liver Disease, ALT, alanine aminotransferase, PEC, portal endothelial cell, Medicine, Humans, Lymphangiogenesis, RT-qPCR, reverse-transcription quantitative polymerase chain reaction, LEC, lymphatic endothelial cell, Original Research, LVD, lymphatic vessel density, Inflammation, Hepatology, hLEC, human lymphatic endothelial cell, business.industry, VEGFR3, vascular endothelial growth factor receptor 3, PDPN, podoplanin, Gastroenterology, HUVEC, human primary umbilical vein endothelial cell, HRP, horseradish peroxidase, LYVE-1, lymphatic vessel endothelial receptor 1, Lymphatic system, TBST, Tris-buffered saline with 0.1% Tween 20 detergent, LN, lymph node, BSA, bovine serum albumin, FITC, fluorescein isothiocyanate, NAFLD, nonalcoholic fatty liver disease, business, NASH, nonalcoholic steatohepatitis, FAO, fatty acid oxidation, CK19, cytokeratin-19
-
10
المؤلفون: Angel Tsz-Yau Wan, Wai-Yee Chan, Heung Man Lee, Juliana C.N. Chan, Zhangting Wang, Alice P.S. Kong, Kai-Kei Miu, Hoi-Hung Cheung, Gang Lu, Xueyan Zhang
المصدر: JHEP Reports
JHEP Reports, Vol 2, Iss 6, Pp 100179-(2020)مصطلحات موضوعية: Hepatic steatosis, HFD, high-fat diet, HFrD, high-fructose drink, OGTT, oral glucose tolerance test, FASN, fatty acid synthase, Glucocorticoid receptor, Diabetes mellitus, AAV, adeno-associated virus, DM, diabetes mellitus, DEG, differentially expressed gene, miRNA, microRNA, Immunology and Allergy, NR3C1, nuclear receptor subfamily 3, group C, member 1, biology, Fatty liver, Gastroenterology, VAT, visceral adipose tissue, MicroRNA, CPT, carnitine palmitoyl transferase, Fatty acid synthase, HOMA-IR, homeostatic model assessment of insulin resistance, Lipogenesis, shRNA, short hairpin RNA, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, DEX, dexamethasone, DNL, de novo lipogenesis, Transcription repressor, Insulin resistance, Internal medicine, 3′-UTR, 3′-untranslated region, Internal Medicine, medicine, lcsh:RC799-869, TAG, triacylglyceride/triglyceride, Hepatology, business.industry, FA, fatty acid, OA, oleic acid, High carbohydrate consumption, SCD1, stearoyl-CoA desaturase-1, T2DM, type 2 diabetes mellitus, medicine.disease, NT, non-targeting, Endocrinology, Nuclear receptor, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, GCR, glucocorticoid receptor, Steatosis, business, FAO, fatty acid oxidation
-
11
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Bioenergetics, Computer science, Computational biology, EFA, extracellular flux analysis, MAS, malate-aspartate shuttle, bioenergetics, Models, Biological, OxPhos, oxidative phosphorylation, Biochemistry, Oxidative Phosphorylation, Respirometry, Oxygen Consumption, ROS, reactive oxygen species, cell metabolism, Neoplasms, SUIT, substrate-inhibitor titration, Metabolic flux analysis, Diabetes Mellitus, Humans, OCR, oxygen consumption rate, Molecular Biology, MFA, metabolic flux analysis, MPC, metal-porphyrin complex, ECAR, extracellular acidification rate, JBC Reviews, Interpretation (philosophy), Genetic Diseases, Inborn, anaerobic glycolysis, Data interpretation, Cell Biology, Mitochondria, ATP, ETS, electron transfer system, Cell metabolism, Anaerobic glycolysis, pmf, proton motive force, RCR, respiratory control ratio, Glycolysis, Flux (metabolism), FAO, fatty acid oxidation
-
12
المؤلفون: Shingo Eikawa, Kouji Hase, Yukihiro Furusawa, Heiichiro Udono, Takenori Uehara, Shohei Hori, Yuki Kunisada, Shohei Domae, Nahoko Tomonobu, Akira Sasaki
المصدر: EBioMedicine
EBioMedicine, Vol 25, Iss C, Pp 154-164 (2017)مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, TIL, tumor infiltrating lymphocyte, mTORC1, T-Lymphocytes, Regulatory, Glut1, glucose transporter 1, Foxp3, forkhead box P3, 0302 clinical medicine, AMP-activated protein kinase, APC, allophycocyanin, AMP-Activated Protein Kinase Kinases, Neoplasms, Tumor immunity, CTLA4, cytotoxic T-lymphocyte-4, Tumor Microenvironment, OCR, oxygen consumption rate, CTLA-4 Antigen, IL-2 receptor, Receptors, Immunologic, KLRG1, killer cell lectin-like receptor G1, GFP, green fluorescent protein, education.field_of_study, lcsh:R5-920, Glucose Transporter Type 1, OVA, Ovalbumin, TMRE, tetramethylrhodamine ethyl ester, FOXP3, hemic and immune systems, IL-10, interleukin-10, CC, compound C, Cell Differentiation, Forkhead Transcription Factors, General Medicine, Metformin, Interleukin-10, Interleukin 10, Treg, T regulatory cell, 030220 oncology & carcinogenesis, TCR, T cell antigen receptor, mTOR, FCCP, Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone, potent mitochondrial oxidative phosphorylation uncoupler, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Glycolysis, Integrin alpha Chains, Research Paper, Met, metformin, CD103, Cluster Designation 103, Integrin αE, RA, rapamycin, FSC, forward scatter, Population, chemical and pharmacologic phenomena, T2D, type 2 diabetes, mTOR, mammalian target of rapamycin, Biology, Regulatory T cell (Treg), Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Antigens, CD, Humans, Lectins, C-Type, iTreg, inducible T regulatory cell, education, Ti-Treg, tumor infiltrating-T regulatory cell, Sirolimus, Tumor microenvironment, ECAR, extracellular acidification rate, CFSE, carboxyfluorescein diacetate succinimidyl ester, lcsh:R, AMPK, CTV, cell trace violet, TGF-β, Transforming growth factor-β1, PE, phycoerythrin, SSC, side scatter, AMPK, AMP-activated protein kinase, 030104 developmental biology, Gene Expression Regulation, biology.protein, Cancer research, Trans-Activators, Protein Kinases, FAO, fatty acid oxidation, ROS, Reactive oxygen species
-
13
المؤلفون: Balaraman Kalyanaraman
المصدر: Redox Biology, Vol 12, Iss, Pp 833-842 (2017)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, H2O, water, Teaching Materials, CoA, acetyl-coenzyme A, OXPHOS, oxidative phosphorylation, Clinical Biochemistry, Review Article, KRAS, V-Ki-ras2 Kirsten rat sarcoma, CO2, carbon dioxide, Biochemistry, G-6P, glucose-6-phosphate, Adenosine Triphosphate, MAGL, monoacylglycerol lipase, MDR, multidrug resistance, NAD+, nicotinamide adenine dinucleotide, Neoplasms, Glycolysis, FDG, fluorinated deoxyglucose, lcsh:QH301-705.5, lcsh:R5-920, LDH, lactate dehydrogenase, FAD, flavin adenine dinucleotide, Warburg effect, Mitochondria, VDAC, voltage-dependent anion channel, LN, lonidamine, BrP, bromopyruvate, GAPDH, glyceraldehyde-3-phosphate, GLUT, glucose transporters, lcsh:Medicine (General), Metabolic Networks and Pathways, ATP, adenosine triphosphate, GIAN, Global Initiative of Academic Networks, ETC, electron transport chain, TCA, tricarboxylic acid, Context (language use), Computational biology, Biology, PET, positron emission tomography, 03 medical and health sciences, 2-DG, 2-deoxyglucose, FFA, free fatty acid, medicine, Animals, Humans, MCT, monocarboxylate transporter, IDH-2, isocitrate dehydrogenase-2, Glutaminolysis, Organic Chemistry, Cancer, TPP+, triphenylphosphonium, HK, hexokinase, NADPH, nicotinamide adenine dinucleotide phosphate, medicine.disease, HIF-1, hypoxia-inducible factor 1, PDH, pyruvate dehydrogenase, Metabolic pathway, 030104 developmental biology, lcsh:Biology (General), Anaerobic glycolysis, PK, pyruvate kinase, Cancer cell, Energy Metabolism, FAO, fatty acid oxidation, PHGDH, 3-phosphoglycerate dehydrogenase, PDK, pyruvate dehydrogenase kinase
-
14
المؤلفون: Jeffrey R. Idle, Diren Beyoğlu, Georg Martin Fiedler, Thomas Pabst, Uta Ceglarek, Linda Kortz
المصدر: Pabst, Thomas; Kortz, Linda; Fiedler, Georg Martin; Ceglarek, Uta; Idle, Jeffrey; Beyoglu, Diren (2017). The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features. BBA clinical, 7, pp. 105-114. Elsevier 10.1016/j.bbacli.2017.03.002 <http://dx.doi.org/10.1016/j.bbacli.2017.03.002>
BBA Clinicalمصطلحات موضوعية: 0301 basic medicine, FAA, fatty acid amide, AA, arachidonic acid, TG, triacylglycerol (triglyceride), chemistry.chemical_compound, PC, phosphatidylcholine, PGF1α, prostaglandin 1α, 0302 clinical medicine, PCA, principal components analysis, Blast cell number, UPLC-ESI-QTOFMS, ultraperformance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry, hemic and lymphatic diseases, MUFA, monounsaturated fatty acid, DG, diacylglycerol, Prognostic risk, CML, chronic myelogenous leukemia, DIC, disseminated intravascular coagulation, 12-HEPE, 12-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid, 610 Medicine & health, AML, acute myeloid leukemia, chemistry.chemical_classification, GCMS, gas chromatography–mass spectrometry, Myeloid leukemia, EPA, eicosapentaenoic acid (20:5, 5Z,8Z,11Z,14Z,17Z), Regular Article, SCD1, stearoyl CoA desaturase 1, PLS-DA, projection to latent structures-discriminant analysis, Lipidome, FLC-QqLIT-MS, fast liquid chromatography-quadrupole linear ion-trap mass spectrometry, MRM, multiple reactions monitoring, Biochemistry, 030220 oncology & carcinogenesis, Molecular Medicine, Arachidonic acid, lipids (amino acids, peptides, and proteins), POEA, palmitoleoyl ethanolamide, Polyunsaturated fatty acid, ESI +, electrospray ionization positive mode, LPE, lysophosphatidylethanolamine, 2HG, (R)-2-hydroxyglutarate, PGH2, prostaglandin H2, MG, monoacylglycerol, Cer, ceramide, PE, phosphatidylethanolamine, CE, cholesterol ester, Pathology and Forensic Medicine, 03 medical and health sciences, PGF2α, prostaglandin F2α, Physiology (medical), 2OG, 2-oxoglutarate, Lipidomics, PUFA, polyunsaturated fatty acid, PGE2, prostaglandin E2, Fatty acids, TxB2, thromboxane B2, mPGES-1, microsomal prostaglandin E synthase-1, LPC, lysophosphatidylcholine, SM, sphingomyelin, Acute myeloid leukemia, Cholesterol, 12-LOX, 12-lipoxygenase, FAME, fatty acid methyl ester, Fatty acid, TxA2, thromboxane A2, OPLS-DA, orthogonal PLS-DA, CPT1a, carnitine palmitate transferase 1a, ALL, acute lymphoblastic leukemia, Sphingolipid, CoQ10, coenzyme Q10, ESI-, electrospray ionization negative mode, 8,9-DHET, 8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid, 030104 developmental biology, chemistry, FAB, French-American-British classification, DGLA, dihomo-γ-linoleic acid, Cancer research, Eicosanoids, FAO, fatty acid oxidation
وصف الملف: application/pdf
-
15
المؤلفون: Diego Rodríguez-Puyol, Laura García-Bermejo, Ricardo Luiz Ramos, Santiago Lamas, Verónica Miguel
المساهمون: Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Comunidad de Madrid, Sociedad Española de Nefrología, Fundación Renal Íñigo Álvarez de Toledo, Fundación Ramón Areces
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology
Redox Biology, Vol 40, Iss, Pp 101851-(2021)مصطلحات موضوعية: 0301 basic medicine, MMP, mitochondrial membrane potential, Clinical Biochemistry, Eto, etomoxir, Mitochondrion, Kidney, Biochemistry, CPT1A, 0302 clinical medicine, Fibrosis, OCR, oxygen consumption rate, Beta oxidation, lcsh:QH301-705.5, lcsh:R5-920, TFAM, mitochondrial transcription factor A, Extracellular matrix, ECM, extracellular matrix, Mitochondria, medicine.anatomical_structure, Fatty acid oxidation, lcsh:Medicine (General), Myofibroblast, Research Paper, Ureteral Obstruction, ITS, insulin-transferrin-selenium, FDR, false discovery rate, Fatty acid oxidation Extracellular matrix, ETC, electron transport chain, Biology, AKI, acute kidney injury, SPF, specific pathogen free, Nephropathy, Transforming Growth Factor beta1, 03 medical and health sciences, MicroRNAS, Kidney fibrosis, FBS, fetal bovine serum, TGF-β, transforming growth factor-β, medicine, Renal fibrosis, miRNAs, microRNAs, Humans, UUO, unilateral ureteral obstruction, ECAR, extracellular acidification rate, Organic Chemistry, CKD, chronic kidney disease, TFAM, medicine.disease, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), Cancer research, FAN, folic acid nephropathy, 030217 neurology & neurosurgery, FAO, fatty acid oxidation, EMT, epithelial-to-mesenchymal transition
-
16
المؤلفون: Gabriele Schoiswohl, Isabelle Strießnig-Bina, Gerald Hoefler, Zhiyuan Tang, Hao Xie, Rudolf Zechner, Martina Schweiger, Paul Vesely, Benedikt Kien, Christoph Heier, Veronika Sexl
المصدر: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids
مصطلحات موضوعية: 0301 basic medicine, IHC, Immunohistochemistry, WAT, White adipose tissue, Proliferation, Mice, 0302 clinical medicine, Neoplasms, NSCLC, Non-small-cell lung carcinoma, shRNA, small hairpin RNA, Cancer, Gene knockdown, BM, Bone marrow, ATGL, Adipose triglyceride lipase, Chemistry, TOR Serine-Threonine Kinases, MEF, Mouse embryonic fibroblasts, DG, Diglyceride, Lipid, Cell biology, SVF, Stroma vascular fractions, 030220 oncology & carcinogenesis, H&E, Haematoxylin/eosin, MGL, Monoacylglycerol lipase, Intracellular, Signal Transduction, Cell signaling, Lipolysis, PBS, Phosphate buffered saline, CGI-58, Comparative gene identification-58, Article, Cell Line, HSL, Hormone-sensitive lipase, TG, Triglyceride, 03 medical and health sciences, ATGL, DMSO, Dimethylsulfoxid, Animals, Humans, FAO, Fatty acid oxidation, Molecular Biology, CD31, Cluster of differentiation 31, Cell Proliferation, Cell growth, Adenylate Kinase, mTOR, Mammalian target of rapamycin, Cell Biology, Lipase, Fibroblasts, Embryonic stem cell, OCR, Oxygen consumption rate, PCNA, Proliferating cell nuclear antigen, MG, Monoglyceride, 030104 developmental biology, FA, Fatty acid, Cancer cell, Adipose triglyceride lipase, AMPK, AMP activated protein kinase, ABHD6, Alpha/beta-hydrolase domain containing 6, G0S2, G0/G1 switch gene 2, HIG2, Hypoxia-inducible gene 2, ROS, Reactive oxygen species
-
17
المؤلفون: Na Li, Yafang Wang, Tiffany Horng, Xin Zhang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, mitochondrial metabolism, FADH2, flavin adenine dinucleotide hydride, OXPHOS, oxidative phosphorylation, GAPDH, glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase, PPAR, peroxisome proliferator-activated receptor, AST, aspartate aminotransferase, PGE2, Prostaglandin E2, Mitochondrion, SUCLG1, succinyl-CoA synthetase, medicine.disease_cause, Biochemistry, DNM1L, macrophage biology, UPR, unfolded protein response, AMP-activated protein kinase, oxidative stress, Citrate synthase, α-KG, α-ketoglutarate, NF-κB, nuclear factor kappa B, NLRP3, NOD-, LRR- and pyrin domain-containing 3, oxPAPC, 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphorylcholine, GAD, glutamic acid decarboxylase, CIC, mitochondrial citrate carrier, biology, Mitochondria, Cell biology, SDH, succinate dehydrogenase, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, PARP, Poly (ADP-ribose) polymerase, TLR, Toll-like receptor, Mitochondrial DNA, NADH, adenine diphosphate hydride, ETC, electron transport chain, TCA, tricarboxylic acid, IDH, isocitrate dehydrogenase, mTOR, mammalian target of rapamycin, Oxidative phosphorylation, MAS, malate-aspartate shuttle, eIF5A, hypusination of translation factor eukaryotic initiation factor 5A, ER, endoplasmic reticulum, 03 medical and health sciences, ΔΨm, mitochondrial membrane potential, IRG1, Immune-Responsive Gene 1, KLF4, Krüppel-like factor 4, macrophage activation, PAMPs, pathogen-associated molecular patterns, mitochondrial dysfunction, Succinate receptor 1, medicine, Animals, Humans, DMF, Dimethyl fumarate, GSDMD, gasdermin D, IFNγ, interferon-γ, MDVs, mitochondria-derived vesicles, Molecular Biology, Drp1, dynamin-related protein 1, SIRT, Sirtuin, PHD, prolyl hydroxylases, NO, nitric oxide, ACLY, ATP citrate lyase, 030102 biochemistry & molecular biology, Macrophages, JBC Reviews, Cell Biology, SUCNR1, succinate receptor 1, HMGB1, high mobility group box 1, mtROS, mitochondrial reactive oxygen species, AMPK, AMP-activated protein kinase, 030104 developmental biology, DAMPs, damage-associated molecular patterns, MHC, Major Histocompatibility Complex, biology.protein, IL-4, interleukin-4, RET, reverse electron transport, GABA, γ-amino butyric acid, HIF-1α, hypoxia inducible factor 1α, OAA, oxaloacetate, FAO, fatty acid oxidation, Oxidative stress
-
18
المؤلفون: Joanna E. Gorka, Jinglin Wang, Sarangarajan Ranganathan, Xiaoguang Chen, Steven F. Dobrowolski, Huabo Wang, Jordan A. Mandel, Eric S. Goetzman, Jie Lu, Marie Schwalbe, Edward V. Prochownik
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Hepatoblastoma, 0301 basic medicine, YAP, yes-associated protein, cancer metabolism, Biochemistry, Mice, chemistry.chemical_compound, Peroxisomal Bifunctional Enzyme, Cpt1a, carnitine palmitoyltransferase 1A, Dodecanedioic acid, metabolic reprogramming, Dicarboxylic Acids, peroxisome, Beta oxidation, fatty acid oxidation, Mice, Knockout, chemistry.chemical_classification, Fatty Acids, Liver Neoplasms, HFDs, high-fat diets, hepatocellular carcinoma, Peroxisome, Mitochondria, ECM, extracellular matrix, Liver, Ehhadh, Ehhadh, enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase, HB, hepatoblastoma, DDDA, dodecanedioic acid, Oxidation-Reduction, Research Article, FDR, false discovery rate, oxidative phosphorylation, TCA, tricarboxylic acid, Biology, 03 medical and health sciences, Downregulation and upregulation, Peroxisomes, medicine, Animals, Humans, Molecular Biology, 030102 biochemistry & molecular biology, Fatty acid, Cell Biology, medicine.disease, Metabolic pathway, Metabolism, 030104 developmental biology, chemistry, OCRs, oxygen consumption rates, Cancer research, Warburg effect, HCC, hepatocellular carcinoma, AcCoA, acetyl coenzyme A, FAO, fatty acid oxidation
-
19
المؤلفون: Abhinav Choubey, Mohan Kamthan, Sangam Rajak, Prosenjit Mondal, Priya Rawat, Surbhi Dogra, Aiysha Siddiq Khan, P. Vineeth Daniel
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, ChREBP, carbohydrate response element-binding protein, NCoRI, nuclear receptor corepressor 1, ChREBP, PDTC, pyrrolidine dithiocarbamate, FASN, fatty acid synthase, Active Transport, Cell Nucleus, ACC, acetyl-CoA carboxylase, DNL, de novo lipogenesis, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, AMP-activated protein kinase, Dietary Carbohydrates, Humans, OCR, oxygen consumption rate, NF-κB p65, Carbohydrate-responsive element-binding protein, sorcin, Molecular Biology, Transcription factor, Beta oxidation, Cell Nucleus, 030102 biochemistry & molecular biology, biology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Lipogenesis, dyslipidemia, Transcription Factor RelA, Acetyl-CoA carboxylase, NF-κB, Hep G2 Cells, Cell Biology, Cell biology, AMPK, AMP-activated protein kinase, Fatty acid synthase, 030104 developmental biology, Liver, chemistry, lipid partitioning, NF-κB, nuclear factor kappa-light chain enhancer of activated B cells, ICC, immunocytochemistry, biology.protein, high carbohydrate diet, NAFLD, nonalcoholic fatty liver disease, SREBP-1c, sterol regulatory element-binding transcription factor 1, FAO, fatty acid oxidation, Research Article
-
20
المؤلفون: Yi Ren, Han-Ming Shen
المصدر: Redox Biology
Redox Biology, Vol 25, Iss, Pp-(2019)مصطلحات موضوعية: AMPK, AICAR, 5-aminoimidazole-4-carboxamide ribonucleotide, MAGE A3/6, melanoma-associated antigen 3/6, OXPHOS, oxidative phosphorylation, DHA, dehydroascorbic acid, PPAR, peroxisome proliferator-activated receptor, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, Biochemistry, G6PD, glucose-6-phosphate dehydrogenase, NADPH, reduced nicotinamide adenine dinucleotide phosphate, 0302 clinical medicine, ARE, antioxidant response, 6PGD, 6-phosphogluconate dehydrogenase, HIF-1α, hypoxia-inducible factor 1-α, GR, glutathione reductase, PPP, the pentose phosphate pathway, Glycolysis, lcsh:QH301-705.5, Cancer, Glucose metabolism, α-KG, α-ketoglutaric acid, Kinase, FAS, fatty acid synthesis, GSSG, oxidized glutathione, SREBP, sterol regulatory element binding protein, ME, malic enzyme, Cell biology, ECM, extracellular matrix, NRF2, nuclear factor (erythroid-derived 2)-like 2, COX-2, cyclooxygenase-2, CRC, colorectal cancer, KEAP1, Kelch-like ECH-associated protein 1, lcsh:Medicine (General), 3PG, 3-phosphoglyceric acid, R-5P, ribose 5-phosphate, KRAS, Kirsten rat sarcoma, IDH, isocitrate dehydrogenase, GLUT1, glucose transporter 1, Pentose phosphate pathway, 6P-2DG, 6-phospho 2-deoxygluconate, mTORC1, mTOR Complex 1, Article, 03 medical and health sciences, LKB1, liver kinase B1, RAPTOR, regulatory-associated protein of mammalian target of rapamycin, ULK1, UNC-51-like kinase 1, Humans, PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1-α, Protein kinase A, Fatty acid metabolism, HK, hexokinase, NQO1, NADPH dehydrogenase (quinone 1), Metabolic pathway, 030104 developmental biology, Glucose, 6P-G, 6-phosphogluconate, NADP+, nicotinamide adenine dinucleotide phosphate, CRM, calorie restriction mimetic, UCP2, mitochondrial uncoupling protein 2, CAT, catalase, 030217 neurology & neurosurgery, FAO, fatty acid oxidation, MAPK, mitogen-activated protein kinase, 0301 basic medicine, ERK2, extracellular signal-regulated kinase 2, GSH, reduced glutathione, PDAC, pancreatic ductal adenocarcinoma, Clinical Biochemistry, FASN, fatty acid synthase, 5TG, 5-thioglucose, HO-1, heme oxygenase 1, medicine.disease_cause, chemistry.chemical_compound, UBE2O, (E3-independent) E2 ubiquitin-conjugating enzyme, Neoplasms, FADH2, the quinone form flavin adenine dinucleotide, Trx, thioredoxin, BRAF, B-Raf proto-oncogene, 2DG-6P, 2-deoxyglucose 6-phosphate, lcsh:R5-920, GPx, glutathione peroxidase, Chemistry, AMPK, 5′ AMP-activated protein kinase, mTOR, the mechanistic target of rapamycin, Glc, glucose, NOX, NADPH oxidases, NADH, the reduced nicotinamide adenine dinucleotide, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, SGLT2, sodium/glucose cotransporter 2, Oxidation-Reduction, CaMKKβ, calcium/calmodulin-dependent protein kinase kinase β, TCA, tricarboxylic acid cycle, CPT1, carnitine palmitoyltransferase 1, PI3K, phosphoinositide-3-kinase, ETC, electron transport chain, G-6P, glucose 6-phosphate, TSC2, tuberous sclerosis complex 2, ROS, reactive oxygen species, MTP, mitochondrial trifunctional protein, NSCLC, non-small cell lung cancer, SOD, superoxide dismutase, medicine, Animals, 2DG, 2-deoxyglucose, MEF, mouse embryonic fibroblasts, TP, trifunctional protein, KO, knockout, MEK, MAPK Kinase, Organic Chemistry, SCD1, stearoyl-CoA desaturase-1, HNE, 4-hydroxy-2-nonenal, TRIM28, tripartite motif-containing 28, PTEN, phosphatase and tensin homolog, Oxidative Stress, lcsh:Biology (General), NAC, N-acetyl cysteine, Reactive oxygen species, Oxidative stress