يعرض 1 - 20 نتائج من 219 نتيجة بحث عن '"F. Zunino"', وقت الاستعلام: 0.52s تنقيح النتائج
  1. 1
    Academic Journal
    Biphenyl-4-yl-acrylohydroxamic acids: identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity

    المؤلفون: R. Cincinelli, V. Zwick, L. Musso, V. Zuco, M. De Cesare, F. Zunino, C. Simoes Pires, A. Nurisso, G. Giannini, M. Cuendet, S. Dallavalle

    المساهمون: R. Cincinelli, V. Zwick, L. Musso, V. Zuco, M. De Cesare, F. Zunino, C. Simoes Pire, A. Nurisso, G. Giannini, M. Cuendet, S. Dallavalle

    مصطلحات موضوعية: Hydroxamic acid, HDAC inhibitor, Antiproliferative activity, Antitumor activity, Synthesis, Settore CHIM/08 - Chimica Farmaceutica, Settore CHIM/06 - Chimica Organica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/26890116; info:eu-repo/semantics/altIdentifier/wos/WOS:000372558200010; volume:112; firstpage:99; lastpage:105; numberofpages:7; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/2434/420166; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84987829354

    الاتاحة: http://hdl.handle.net/2434/420166
    https://doi.org/10.1016/j.ejmech.2016.02.001

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  2. 2
    Academic Journal
    3-Arylidene-N-hydroxyoxindoles : a new class of compounds endowed with antitumor activity

    المؤلفون: L. Musso, R. Cincinelli, V. Zuco, M. Decesare, F. Zunino, A. L. Fallacara, M. Botta, S. Dallavalle

    المساهمون: L. Musso, R. Cincinelli, V. Zuco, M. Decesare, F. Zunino, A.L. Fallacara, M. Botta, S. Dallavalle

    مصطلحات موضوعية: Antiproliferative activity, Antitumor agent, Apoptosi, N-hydroxyoxindole, P53, Settore CHIM/08 - Chimica Farmaceutica, Settore CHIM/06 - Chimica Organica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/27311681; info:eu-repo/semantics/altIdentifier/wos/WOS:000383579700005; National Meeting of the Medicinal-Chemistry-Division of the Italian-Chemical-Society (DCF-SCI); volume:11; issue:16; firstpage:1700; lastpage:1704; numberofpages:5; journal:CHEMMEDCHEM; http://hdl.handle.net/2434/431069; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84983239017

    الاتاحة: http://hdl.handle.net/2434/431069
    https://doi.org/10.1002/cmdc.201600225

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  3. 3
    Academic Journal
    Perspectives in the development of hybrid bifunctional antitumour agents

    المؤلفون: L. Musso, S. Dallavalle, F. Zunino

    المساهمون: L. Musso, S. Dallavalle, F. Zunino

    مصطلحات موضوعية: Dual action, Hybrid, Bifunctional antitumor agent, Drugs design, Multitarget compounds, Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/26074269; info:eu-repo/semantics/altIdentifier/wos/WOS:000359393600001; volume:96; issue:4; firstpage:297; lastpage:305; numberofpages:9; journal:BIOCHEMICAL PHARMACOLOGY; http://hdl.handle.net/2434/336373; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84938291452

    الاتاحة: http://hdl.handle.net/2434/336373
    https://doi.org/10.1016/j.bcp.2015.06.006

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  4. 4
    Academic Journal
    Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors

    المؤلفون: L. Musso, R. Cincinelli, V. Zuco, F. Zunino, A. Nurisso, M. Cuendet, G. Giannini, L. Vesci, C. Pisano, S. Dallavalle

    المساهمون: L. Musso, R. Cincinelli, V. Zuco, F. Zunino, A. Nurisso, M. Cuendet, G. Giannini, L. Vesci, C. Pisano, S. Dallavalle

    مصطلحات موضوعية: Antiproliferative activity, Histone deacetylase (HDAC) inhibitor, Synthesi, Zn-binding group, Biochemistry, Clinical Biochemistry, Molecular Biology, Molecular Medicine, Organic Chemistry, Drug Discovery3003 Pharmaceutical Science, Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Time: 3003

    Relation: info:eu-repo/semantics/altIdentifier/pmid/26376355; info:eu-repo/semantics/altIdentifier/wos/WOS:000362102200016; volume:25; issue:20; firstpage:4457; lastpage:4460; numberofpages:4; journal:BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; http://hdl.handle.net/2434/336381; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84942825718

    الاتاحة: http://hdl.handle.net/2434/336381
    https://doi.org/10.1016/j.bmcl.2015.09.006

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  5. 5
    Academic Journal
    Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors

    المؤلفون: R. Cincinelli, L. Musso, G. Giannini, V. Zuco, M. De Cesare, F. Zunino, S. Dallavalle

    المساهمون: R. Cincinelli, L. Musso, G. Giannini, V. Zuco, M. De Cesare, F. Zunino, S. Dallavalle

    مصطلحات موضوعية: Adamantyl moiety, Hydroxamic acid, HDAC inhibitor, Antiproliferative activity, Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/24742384; info:eu-repo/semantics/altIdentifier/wos/WOS:000336700600025; volume:79; firstpage:251; lastpage:259; numberofpages:9; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/2434/234557; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84921998819

    الاتاحة: http://hdl.handle.net/2434/234557
    https://doi.org/10.1016/j.ejmech.2014.04.021

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  6. 6
    Academic Journal
    7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors

    المؤلفون: R. Cincinelli, L. Musso, L. Merlini, G. Giannini, L. Vesci, F. M. Milazzo, N. Carenini, P. Perego, S. Penco, R. Artali, F. Zunino, C. Pisano, S. Dallavalle

    المساهمون: R. Cincinelli, L. Musso, L. Merlini, G. Giannini, L. Vesci, F.M. Milazzo, N. Carenini, P. Perego, S. Penco, R. Artali, F. Zunino, C. Pisano, S. Dallavalle

    مصطلحات موضوعية: PARP inhibitor, Synthesi, Molecular modelling, 7-Azaindole, Antitumor, Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/24398383; info:eu-repo/semantics/altIdentifier/wos/WOS:000329977300017; volume:22; issue:3; firstpage:1089; lastpage:1103; numberofpages:15; journal:BIOORGANIC & MEDICINAL CHEMISTRY; http://hdl.handle.net/2434/230356; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84892805503

    الاتاحة: http://hdl.handle.net/2434/230356
    https://doi.org/10.1016/j.bmc.2013.12.031

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  7. 7
    Academic Journal
    Design, modeling, synthesis and biological activity evaluation of camptothecin linked platinum anticancer agents

    المؤلفون: R. Cincinelli, L. Musso, S. Dallavalle, R. Artali, S. Tinelli, D. Colangelo, F. Zunino, M. De Cesare, G. L. Beretta, N. Zaffaroni

    المساهمون: R. Cincinelli, L. Musso, S. Dallavalle, R. Artali, S. Tinelli, D. Colangelo, F. Zunino, M. De Cesare, G.L. Beretta, N. Zaffaroni

    مصطلحات موضوعية: Antitumor compound, Docking, Camptothecin, Diaminedichloro-platinum (II), Settore CHIM/06 - Chimica Organica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/23517728; info:eu-repo/semantics/altIdentifier/wos/WOS:000322855400037; volume:63; firstpage:387; lastpage:400; numberofpages:14; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/2434/218926; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84875007757

    الاتاحة: http://hdl.handle.net/2434/218926
    https://doi.org/10.1016/j.ejmech.2013.02.022

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  8. 8
    Academic Journal
    REST Controls Self-Renewal and Tumorigenic Competence of Human Glioblastoma Cells

    المؤلفون: L. Conti, L. Crisafulli, P. Conforti, E. Cattaneo, V. Caldera, M. Tortoreto, E. Brilli, F. Zunino, L. Magrassi, D. Schiffer

    المساهمون: L. Conti, L. Crisafulli, V. Caldera, M. Tortoreto, E. Brilli, P. Conforti, F. Zunino, L. Magrassi, D. Schiffer, E. Cattaneo

    مصطلحات موضوعية: microRNA 124, protein REST, repressor element 1 silencing transcription factor, repressor protein, transcription factor, animal cell, animal experiment, animal model, article, carcinogenesi, cell compartmentalization, cell renewal, controlled study, downstream processing, glioblastoma, human, human cell, human tissue, in vitro study, in vivo study, mouse, nonhuman, protein expression, protein function, protein targeting, tumor cell, Settore BIO/14 - Farmacologia

    Relation: info:eu-repo/semantics/altIdentifier/pmid/22701651; info:eu-repo/semantics/altIdentifier/wos/WOS:000305337600026; volume:7; issue:6; firstpage:1; lastpage:13; numberofpages:13; journal:PLOS ONE; http://hdl.handle.net/2434/206846; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84862188342

    الاتاحة: http://hdl.handle.net/2434/206846
    https://doi.org/10.1371/journal.pone.0038486

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  9. 9
    Academic Journal
    Histone Deacetylase and Microtubules as Targets for the Synthesis of Releasable Conjugate Compounds

    المؤلفون: D. Passarella, D. Comi, FERRANTE, LUCA, B. Danieli, A. Vanossi, G. Paganini, F. Colombo, V. Zuco, F. Zunino

    المساهمون: D. Passarella, D. Comi, A. Vanossi, G. Paganini, F. Colombo, L. Ferrante, V. Zuco, B. Danieli, F. Zunino

    مصطلحات موضوعية: Anticancer compound, Disulfide bond, HDAC inhibitor, Releasable conjugate compound, Tubulin binders, Settore CHIM/06 - Chimica Organica

    Relation: info:eu-repo/semantics/altIdentifier/pmid/19833515; info:eu-repo/semantics/altIdentifier/wos/WOS:000271029600022; volume:19; issue:22; firstpage:6358; lastpage:6363; journal:BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; http://hdl.handle.net/2434/142765; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-71049188845

    الاتاحة: http://hdl.handle.net/2434/142765
    https://doi.org/10.1016/j.bmcl.2009.09.075

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  10. 10
    Academic Journal
    metabolic approach to the enhancement of antitumor effect of chemotherapy a key role of acetyl l carnitine

    المؤلفون: C. Pisano, L. Vesci, F. M. Milazzo, M. B. Guglielmi, R. Fodera, M. Barbarino, M. D'Incalci, M. Zucchetti, G. Petrangolini, M. Tortoreto, P. Perego, V. Zuco, A. Orlandi, D. Passeri, P. Carminati, C. Cavazza, F. Zunino

    مصطلحات موضوعية: Cancer Research, Oncology

    Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/49444

    الاتاحة: https://www.openaccessrepository.it/record/49444
    https://doi.org/10.1158/1078-0432.ccr-10-0964

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  11. 11
    Conference
    3-Arylideneindolin-2-ones as inhibitors of MDM2-p53 interaction

    المؤلفون: L. Musso, R. Cincinelli, S. Dallavalle, F. Zunino, A. L. Fallacara, M. Botta, R. Cetin Atalay, D. Gozen

    المساهمون: L. Musso, R. Cincinelli, S. Dallavalle, F. Zunino, A.L. Fallacara, M. Botta, R. Cetin Atalay, D. Gozen

    مصطلحات موضوعية: Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Relation: Workshop; http://hdl.handle.net/2434/269145

    الاتاحة: http://hdl.handle.net/2434/269145

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  12. 12
    Conference
    Novel HDAC inhibitors with a phenylcinnamic scaffold: synthesis and evaluation of antitumor activity

    المؤلفون: L. Musso, R. Cincinelli, S. Dallavalle, F. Zunino, V. Zwick, C. Simoes Pires, A. Nurisso, M. Cuendet

    المساهمون: L. Musso, R. Cincinelli, F. Zunino, V. Zwick, C. Simoes Pire, A. Nurisso, M. Cuendet, S. Dallavalle

    مصطلحات موضوعية: Settore CHIM/06 - Chimica Organica, Settore CHIM/08 - Chimica Farmaceutica

    Relation: Chemical approaches to targeting drug resistance in cancer stem cells; http://hdl.handle.net/2434/269141

    الاتاحة: http://hdl.handle.net/2434/269141

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  13. 13
    Conference
    NATURAL AND SEMISYNTHETIC AZAPHILONES AS A NEW SCAFFOLD FOR Hsp90 INHIBITORS

    المؤلفون: L. Musso, S. Dallavalle, L. Merlini, A. Bava, G. Nasini, S. Penco, G. Giannini, C. Giommarelli, A. De Cesare, V. Zuco, L. Vesci, C. Pisano, M. Castorina, F. Milazzo, F. Dal Piaz, N. De Tommasi, F. Zunino

    المساهمون: L. Musso, S. Dallavalle, L. Merlini, A. Bava, G. Nasini, S. Penco, G. Giannini, C. Giommarelli, A. De Cesare, V. Zuco, L. Vesci, C. Pisano, M. Castorina, F. Milazzo, F. Dal Piaz, N. De Tommasi, F. Zunino

    مصطلحات موضوعية: azaphilones, bulgarialactone B, Hsp90 inhibitors, client proteins, surface plasmon resonance, limited proteolysis assays, antiproliferative activity, Settore CHIM/06 - Chimica Organica

    Relation: NatPharma : Nature Aided Drug Discovery; http://hdl.handle.net/2434/161229

    الاتاحة: http://hdl.handle.net/2434/161229

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  14. 14
    Academic Journal
    Targeting the invasive phenotype of cisplatin-resistant non-small lung cancer cells by a novel histone deacetylase inhibitor

    المؤلفون: V. Zuco, G. Cassinelli, G. Cossa, L. Gatti, E. Favini, M. Tortoreto, D. Cominetti, R. Cincinelli, G. Giannini, F. Zunino, N. Zaffaroni, C. Lanzi, P. Perego, E. Scanziani, V. Castiglioni

    المساهمون: V. Zuco, G. Cassinelli, G. Cossa, L. Gatti, E. Favini, M. Tortoreto, D. Cominetti, E. Scanziani, V. Castiglioni, R. Cincinelli, G. Giannini, F. Zunino, N. Zaffaroni, C. Lanzi, P. Perego

    مصطلحات موضوعية: Non-Small-Cell Lung Cancer, cisplatin, drug resistance, histone deacetylase inhibitor, Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria

    Relation: info:eu-repo/semantics/altIdentifier/pmid/25600908; info:eu-repo/semantics/altIdentifier/wos/WOS:000351479500004; volume:94; issue:22; firstpage:79; lastpage:90; numberofpages:12; journal:BIOCHEMICAL PHARMACOLOGY; http://hdl.handle.net/2434/262140; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84923914541

    الاتاحة: http://hdl.handle.net/2434/262140
    https://doi.org/10.1016/j.bcp.2015.01.002

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  15. 15
    Conference
    Multi tyrosine kinase targeting in concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells

    المؤلفون: G. Cassinelli, D. Laccabue, M. Mattioli, G. Cuccuru, E. Favini, V. Nicolini, A. Greco, F. Zunino, C. Lanzi, D. Ronchetti, A. Neri

    المساهمون: G. Cassinelli, D. Ronchetti, D. Laccabue, M. Mattioli, G. Cuccuru, E. Favini, V. Nicolini, A. Greco, A. Neri, F. Zunino, C. Lanzi

    مصطلحات موضوعية: Settore MED/15 - Malattie del Sangue

    Relation: AACR-NCI-EORTC International Conference : Molecular Targets and Cancer Therapeutics; http://hdl.handle.net/2434/69630

    الاتاحة: http://hdl.handle.net/2434/69630

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  16. 16
    Conference
    Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting

    المؤلفون: V. Nicolini, G. Cassinelli, D. Ronchetti, D. Laccabue, M. Mattioli, G. Cuccuru, A. Greco, F. Zunino, C. Lanzi, F. Favini, A. Neri

    المساهمون: V. Nicolini, G. Cassinelli, D. Ronchetti, D. Laccabue, M. Mattioli, G. Cuccuru, A. Greco, A. Neri, F. Zunino, C. Lanzi, F. Favini

    مصطلحات موضوعية: Settore MED/15 - Malattie del Sangue

    Relation: Annual Meeting of the Italian Cancer Society; http://hdl.handle.net/2434/70118

    الاتاحة: http://hdl.handle.net/2434/70118

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  17. 17
    Conference
    Multi-tyrosine kinase targeting in concomitant down regulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells

    المؤلفون: G. Cassinelli, D. Ronchetti, D. Laccabue, M. Mattioli, G. Cuccuru, E. Favini, V. Nicolini, A. Greco, F. Zunino, C. Lanzi, A. Neri

    المساهمون: G. Cassinelli, D. Ronchetti, D. Laccabue, M. Mattioli, G. Cuccuru, E. Favini, V. Nicolini, A. Greco, A. Neri, F. Zunino, C. Lanzi

    مصطلحات موضوعية: Settore MED/15 - Malattie del Sangue

    Relation: AACR-NCI-EORTC international conference : molecular targets and cancer therapeutics; http://hdl.handle.net/2434/69909

    الاتاحة: http://hdl.handle.net/2434/69909

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  18. 18
    Conference
    Synthesis, modeling and RET protein kinase inhibitory activity of substituted β-carbolin-2-ones and dihydro-2H-azepino3,4-bindol-1-ones

    المؤلفون: R. CINCINELLI, G. CASSINELLI, S. DALLAVALLE, C. LANZI, L. MERLINI, M. BOTTA, S. PENCO, F. ZUNINO, MARTINELLI, ADRIANO, TUCCINARDI, TIZIANO

    المساهمون: R., Cincinelli, G., Cassinelli, S., Dallavalle, C., Lanzi, L., Merlini, M., Botta, Martinelli, Adriano, Tuccinardi, Tiziano, S., Penco, F., Zunino

    Relation: ispartofbook:XIX National Meeting on Medicinal Chemistry; XIX National Meeting on Medicinal Chemistry; http://hdl.handle.net/11568/126642

    الاتاحة: http://hdl.handle.net/11568/126642

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  19. 19
    Conference
    Synthesis, molecular modelling and cytotoxicity of new 1,3,4-oxadiazoles derivatives with antimitotic activity

    المؤلفون: S. Villa, R. Artali, G. Cignarella, G. A. Pinna, F. Zunino, E. Villa

    المساهمون: S. Villa, G.A. Pinna, F. Zunino, R. Artali, G. Cignarella, E. Villa

    مصطلحات موضوعية: Settore CHIM/08 - Chimica Farmaceutica

    Relation: Meeeting on Medicinal Chemistry; http://hdl.handle.net/2434/62189

    الاتاحة: http://hdl.handle.net/2434/62189

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  20. 20
    Conference
    Synthesis, cytotoxic activity and DNA-interaction studies if a new sweies of Topoisomerase I inhibitors

    المؤلفون: S. Dallavalle, GATTINONI, SONIA, L. Merlini, MONDELLI, ROSANNA, L. Scaglioni, G. L. Beretta, F. Zunino

    المساهمون: S. Dallavalle, S. Gattinoni, L. Merlini, R. Mondelli, L. Scaglioni, G.L. Beretta, F. Zunino

    مصطلحات موضوعية: Settore CHIM/06 - Chimica Organica

    Relation: DNA Supercoiling & Topoisomerases; http://hdl.handle.net/2434/42090

    الاتاحة: http://hdl.handle.net/2434/42090

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