المؤلفون: F. P. Guengerich, Slobodan Rendic

المصدر: Curr Drug Metab

مصطلحات موضوعية: Drug, media_common.quotation_subject, Clinical Biochemistry, Pharmacology, 030226 pharmacology & pharmacy, Article, 03 medical and health sciences, 0302 clinical medicine, Cytochrome P-450 Enzyme System, In vivo, Chloroquine, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Medicine, Drug Interactions, ADME, media_common, chemistry.chemical_classification, biology, business.industry, COVID-19, Membrane Transport Proteins, Cytochrome P450, Hydroxychloroquine, COVID-19 Drug Treatment, Enzyme, Pharmaceutical Preparations, chemistry, 030220 oncology & carcinogenesis, biology.protein, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25585a74101a1a1fc40d9c5fc44d6586
https://doi.org/10.2174/1389200221999201208211537

المؤلفون: Irina A. Pikuleva, F P Guengerich, Wilkey Cj, Peter Verwilst, Natalia Mast

المصدر: J Med Chem

مصطلحات موضوعية: Cyclopropanes, Efavirenz, Protein Conformation, Allosteric regulation, Cytochrome P-450 CYP3A Inducers, In Vitro Techniques, Hydroxylation, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, immune system diseases, Catalytic Domain, parasitic diseases, Drug Discovery, Cholesterol 24-Hydroxylase, Humans, heterocyclic compounds, Cholesterol 24-hydroxylase, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Cholesterol, virus diseases, Cytochrome P450, biochemical phenomena, metabolism, and nutrition, Benzoxazines, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Pharmaceutical Preparations, chemistry, Biochemistry, Alkynes, biology.protein, Molecular Medicine, Allosteric Site

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4638d56eb4c0f479fe518a95ad66f3f8
https://doi.org/10.1021/acs.jmedchem.9b01383

المؤلفون: Pavel Soucek, Shouzou Wei, F. P. Guengerich, Renata Kozevnikovova, Yune-Fang Ueng, David Vrána

المصدر: Clinical Chemistry and Laboratory Medicine (CCLM). 56:e78-e81

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, medicine.drug_class, Metabolite, Clinical Biochemistry, Estrogen receptor, Breast Neoplasms, medicine.disease_cause, Article, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, Internal medicine, polycyclic compounds, Adjuvant therapy, Humans, Medicine, business.industry, Cholesterol, Biochemistry (medical), General Medicine, medicine.disease, In vitro, 030104 developmental biology, chemistry, Estrogen, Cancer research, Female, lipids (amino acids, peptides, and proteins), business, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc4ad7abebbcead3c967883742b0d5c
https://doi.org/10.1515/cclm-2017-0409

المؤلفون: Yueh Ching Chou, Sheng Fan Wang, Chiung Chiao Huang, Shouzuo Wei, F. P. Guengerich, Yu Ping Chang, Pavel Soucek, Yune-Fang Ueng, Ping Shan Lai, Pei Hsin Chou, Chun Wei Wang

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, 27-hydroxycholesterol, Estrogen receptor, Pharmacology, P-glycoprotein, doxorubicin, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, medicine, Doxorubicin, Protein kinase B, PI3K/AKT/mTOR pathway, 7-ketocholesterol, biology, business.industry, medicine.disease, 3. Good health, 030104 developmental biology, Oncology, chemistry, 27-Hydroxycholesterol, biology.protein, business, Fetal bovine serum, medicine.drug, Research Paper, estrogen receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4596078292337c4db300a6a9e95fd7
http://europepmc.org/articles/PMC5630390

المؤلفون: F. P. Guengerich, P. P. Ghodke

مصطلحات موضوعية: chemistry.chemical_compound, RNTP, biology, Chemistry, Stereochemistry, RNase P, biology.protein, RNA, Pyrimidine dimer, Primer (molecular biology), Reverse transcriptase, Polymerase, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a6b33201a51d4664f1d30f817f70f313
https://doi.org/10.1039/9781839162541-00164

المؤلفون: Yi Xiao, Joseph C. Corbo, Jennifer M. Enright, Thanh T.N. Phan, F. P. Guengerich, Matthew B. Toomey, Leslie D. Nagy, Kevin M. Johnson, Valerie M. Kramlinger, Rina Fujiwara

المصدر: FEBS Letters. 590:1304-1312

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Biophysics, Retinoic acid, Biochemistry, Article, law.invention, Retinoids, 03 medical and health sciences, chemistry.chemical_compound, food, Structural Biology, law, Genetics, medicine, Humans, Cytochrome P450 Family 27, Retinoid, Molecular Biology, Vitamin a1, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Retinol, Cytochrome P450, Retinal, Cell Biology, 030104 developmental biology, Enzyme, chemistry, biology.protein, Recombinant DNA, food.nutrient

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0770eccebc730613af58a52757a524ba
https://doi.org/10.1002/1873-3468.12167

المؤلفون: Yingjun Su, F. P. Guengerich, Christopher J. Wilds, Amritraj Patra, Martin Egli, Derek K. O'Flaherty

المصدر: Chemical Science. 7:4896-4904

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, biology, Stereochemistry, Oligonucleotide, DNA damage, DNA polymerase, General Chemistry, Molecular biology, Nucleobase, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Coding strand, biology.protein, Nucleotide, Polymerase, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ccb5cb2358219f1c00ff47fc5a7764be
https://doi.org/10.1039/c6sc00666c

المؤلفون: F. P. Guengerich, Slobodan Rendic

المصدر: Current drug metabolism. 19(1)

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Database, Databases, Factual, Computer science, Clinical Biochemistry, Low activity, computer.software_genre, Article, 03 medical and health sciences, chemistry.chemical_compound, Clinical therapy, 030104 developmental biology, Benzo(a)pyrene, chemistry, Cytochrome P-450 CYP1B1, Cytochrome P-450 CYP1A1, Animals, Humans, Medline database, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887cae445b9ae9705bd847f5fc6ce3fc
https://pubmed.ncbi.nlm.nih.gov/29219051

المؤلفون: F. P. Guengerich

المصدر: Drug Metabolism Prediction

مصطلحات موضوعية: chemistry.chemical_classification, Enzyme, Biochemistry, biology, chemistry, CYP1A2, biology.protein, Structure–activity relationship, Cytochrome P450, Pharmacology, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e3fd76c563ce28eed6ee195b002dc7b4
https://doi.org/10.1002/9783527673261.ch08

المؤلفون: Qianqian Zhang, L. Muller, Yingjun Su, Amritraj Patra, Leslie D. Nagy, F. P. Guengerich, Martin Egli

المصدر: Journal of Biological Chemistry. 289:16867-16882

مصطلحات موضوعية: Guanine, Stereochemistry, DNA damage, Molecular Sequence Data, DNA-Directed DNA Polymerase, DNA and Chromosomes, Biology, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Catalytic Domain, Humans, heterocyclic compounds, Nucleotide, Amino Acid Sequence, Transversion, Molecular Biology, Polymerase, chemistry.chemical_classification, Nucleotides, Active site, Cell Biology, Molecular Docking Simulation, RING finger domain, Kinetics, chemistry, biology.protein, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31126c1b4e20257b00583e0693ad4eb
https://doi.org/10.1074/jbc.m114.551820

المؤلفون: F. P. Guengerich

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Hydrogen atom abstraction, Article, Substrate Specificity, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Kinetic isotope effect, Humans, Organic chemistry, Bond cleavage, Enzyme Assays, biology, Cytochrome P450, Hydrogen Bonding, Deuterium, Kinetics, 030104 developmental biology, Models, Chemical, chemistry, Biocatalysis, biology.protein, Oxidation-Reduction, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d129e38b300d21946344b36e878c15
https://doi.org/10.1016/bs.mie.2017.06.036

المؤلفون: Masayuki Komori, Shotaro Uehara, Norie Murayama, Shigeo Takenaka, Donghak Kim, Nobuyuki Koga, F. P. Guengerich, Hiroshi Yamazaki, Kensaku Kakimoto, Tsutomu Shimada

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Pharmaceutical Science, 010501 environmental sciences, Ligands, 01 natural sciences, Catalysis, Cytochrome P-450 CYP2A6, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Catalytic Domain, Animals, Humans, CYP2A6, Heme, 0105 earth and related environmental sciences, Pharmacology, chemistry.chemical_classification, biology, Ligand, Cytochrome P450, Articles, Haplorhini, Polychlorinated Biphenyls, Amino acid, Molecular Docking Simulation, 030104 developmental biology, CYP2A13, Enzyme, Biochemistry, chemistry, biology.protein, Oxidation-Reduction, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4711d4bd8f0dee8d7e18f2ccd31d4f62
https://europepmc.org/articles/PMC6047209/

المؤلفون: D K, O'Flaherty, A, Patra, Y, Su, F P, Guengerich, M, Egli, C J, Wilds

المصدر: Chemical science. 7(8)

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dcb8b1d346b4106c2cd45b1ec0df0b3d
https://pubmed.ncbi.nlm.nih.gov/27574558

المؤلفون: Slobodan Rendic, F P Guengerich

المصدر: Current Drug Metabolism. 11:4-84

مصطلحات موضوعية: Pharmacology, Drug, media_common.quotation_subject, Clinical Biochemistry, Transporter, Computational biology, Disease, Biology, Isozyme, Carrier protein, Cyp enzymes, Drug metabolism, Human cytochrome, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::59de72c95d8a19ee71680c46e9e7240a
https://doi.org/10.2174/138920010791110917

المؤلفون: F. P. Guengerich, Katarina Stark, Miroslav Dostálek

المصدر: FEBS Journal. 275:3706-3717

مصطلحات موضوعية: chemistry.chemical_classification, Messenger RNA, biology, Cytochrome P450, Cell Biology, Anandamide, Biochemistry, Endocannabinoid system, Amino acid, chemistry.chemical_compound, chemistry, biology.protein, Ethanolamide, Arachidonic acid, Heterologous expression, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93bc0239b3bc82818134d1737f791274
https://doi.org/10.1111/j.1742-4658.2008.06518.x

المؤلفون: P. F. X. Corvini, Andreas Schäffer, F. P. Guengerich, Boris A. Kolvenbach, S. Zühlke, Jürgen Prell, N. Schlaich, Z. Raoui

المصدر: Applied and Environmental Microbiology. 73:4776-4784

مصطلحات موضوعية: endocrine system, Bisphenol A, Bisphenol, Stereochemistry, Stereoisomerism, Oxygen Isotopes, Sphingomonas, Applied Microbiology and Biotechnology, Hydroxylation, chemistry.chemical_compound, Phenols, Carbon Radioisotopes, Benzhydryl Compounds, Chromatography, High Pressure Liquid, Molecular Structure, Ecology, Hydroquinone, biology, urogenital system, Chemistry, biology.organism_classification, Nonylphenol, Biodegradation, Environmental, Models, Chemical, Biodegradation, Isopropyl, Food Science, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58066657a8637faf8e0123d8b7333760
https://doi.org/10.1128/aem.00329-07

المؤلفون: Norie Murayama, M. Minoshima, Makiko Shimizu, F. P. Guengerich, Hiroshi Yamazaki

المصدر: Xenobiotica. 37:717-724

مصطلحات موضوعية: CYP2B6, Cytochrome, Health, Toxicology and Mutagenesis, Oxidative phosphorylation, Pharmacology, Hydroxylation, Toxicology, Biochemistry, chemistry.chemical_compound, medicine, Humans, Propofol, CYP3A4, biology, Chemistry, CYP1A2, General Medicine, Steroid Hydroxylases, Microsomes, Liver, Microsome, biology.protein, Aryl Hydrocarbon Hydroxylases, Anesthetics, Intravenous, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf23ea69b0ffed6d53582a724372aad
https://doi.org/10.1080/00498250701449431

المؤلفون: H.-J. Kim, S.-B. Lee, M.-S. Dong, Y. I. Park, F. P. Guengerich

المصدر: Xenobiotica. 37:356-365

مصطلحات موضوعية: Stereochemistry, Health, Toxicology and Mutagenesis, Gene Expression, Reductase, Toxicology, Biochemistry, Catalysis, law.invention, Cytochrome P-450 CYP1A2, law, Oxazines, Escherichia coli, Humans, Amino Acid Sequence, Pharmacology, chemistry.chemical_classification, biology, CYP1A2, Cytochrome P450, Cytochrome P450 reductase, Membranes, Artificial, General Medicine, biology.organism_classification, Recombinant Proteins, Amino acid, Enzyme, chemistry, Mutagenesis, biology.protein, Recombinant DNA, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0efabe77666886f84d3e63b90dee22
https://doi.org/10.1080/00498250601178189

المؤلفون: Leslie D. Nagy, F. P. Guengerich, Eric Gonzalez

المصدر: The FASEB Journal. 29

مصطلحات موضوعية: chemistry.chemical_compound, Biochemistry, Biosynthesis, chemistry, Kinetic analysis, Genetics, Processivity, Molecular Biology, Biotechnology, Human cytochrome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1468316b4164e9f3244b208149b7a898
https://doi.org/10.1096/fasebj.29.1_supplement.722.13

المؤلفون: Keon-Hee Kim, F. P. Guengerich, Dong-Hyun Kim, Chul-Ho Yun, Emre M. Isin

المصدر: FEBS Journal. 273:2223-2231

مصطلحات موضوعية: Stereochemistry, Kinetics, 7-Alkoxycoumarin O-Dealkylase, Binding, Competitive, Biochemistry, Catalysis, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP1A2, Kinetic isotope effect, Animals, Humans, Molecular Biology, Molecular Structure, Substrate (chemistry), Cell Biology, Deuterium, Coumarin, Rats, chemistry, Isotope Labeling, Intramolecular force, Microsomes, Liver, Microsome, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6302a179d92cbe490c9271180540075
https://doi.org/10.1111/j.1742-4658.2006.05235.x