المؤلفون: Magdalena Łysakowska, Iwona E. Głowacka, Ewelina Honkisz-Orzechowska, Jadwiga Handzlik, Dorota G. Piotrowska

المصدر: Molecules, Vol 29, Iss 13, p 3050 (2024)

مصطلحات موضوعية: cis/trans-isoxazolidines, quinazoline-2,4-diones, phosphonates, anticancer activity, apoptosis, safety, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/13/3050; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/b6bb75c24596445f9790ed339e54bf83

المؤلفون: Anna Stasiak, Ewelina Honkisz-Orzechowska, Zbigniew Gajda, Waldemar Wagner, Katarzyna Popiołek-Barczyk, Kamil J. Kuder, Gniewomir Latacz, Michał Juszczak, Katarzyna Woźniak, Tadeusz Karcz, Katarzyna Szczepańska, Marta Jóźwiak-Bębenista, Katarzyna Kieć-Kononowicz, Dorota Łażewska

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 15, p 8035 (2024)

مصطلحات موضوعية: histamine H 3 receptor, chalcone, metabolic stability, cytotoxicity, neuroprotection, analgesic activity, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/15/8035; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/07f15c28e5634125bbc9b416bd8c2a3d

الاتاحة: https://doi.org/10.3390/ijms25158035
https://doaj.org/article/07f15c28e5634125bbc9b416bd8c2a3d

المؤلفون: Ewelina Honkisz-Orzechowska, Dorota Łażewska, Grzegorz Baran, Katarzyna Kieć-Kononowicz

المصدر: Molecules, Vol 29, Iss 6, p 1258 (2024)

مصطلحات موضوعية: GPR18, agonist, antagonist, resolvin D2, inflammation, resolution, Organic chemistry, QD241-441

Relation: https://www.mdpi.com/1420-3049/29/6/1258; https://doaj.org/toc/1420-3049; https://doaj.org/article/83d7208dabf44b74b88d8ee8337442dd

الاتاحة: https://doi.org/10.3390/molecules29061258
https://doaj.org/article/83d7208dabf44b74b88d8ee8337442dd

المؤلفون: Ewelina Honkisz-Orzechowska, Olga Barczyk-Woźnicka, Maria Kaleta, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 11, p 6100 (2024)

مصطلحات موضوعية: fibrosarcoma, autophagy, LC3-II, apoptosis, indole-based chalcone, MIPP, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/11/6100; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/fa698ba49c88436f95702c1791025128

الاتاحة: https://doi.org/10.3390/ijms25116100
https://doaj.org/article/fa698ba49c88436f95702c1791025128

المؤلفون: Michał Załuski, Dorota Łażewska, Piotr Jaśko, Ewelina Honkisz-Orzechowska, Kamil J. Kuder, Andreas Brockmann, Gniewomir Latacz, Małgorzata Zygmunt, Maria Kaleta, Beril Anita Greser, Agnieszka Olejarz-Maciej, Magdalena Jastrzębska-Więsek, Christin Vielmuth, Christa E. Müller, Katarzyna Kieć-Kononowicz

المصدر: International Journal of Molecular Sciences ; Volume 24 ; Issue 18 ; Pages: 13707

مصطلحات موضوعية: adenosine A 2A receptor, adenosine A 1 receptor, xanthine derivatives, anti-inflammatory activity, Griess assay, phagocytic activity, molecular modelling, metabolic stability

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms241813707

الاتاحة: https://doi.org/10.3390/ijms241813707

المؤلفون: Agnieszka Olejarz-Maciej, Szczepan Mogilski, Tadeusz Karcz, Tobias Werner, Katarzyna Kamińska, Jarosław Kupczyk, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Holger Stark, Katarzyna Kieć-Kononowicz, Dorota Łażewska

المصدر: Molecules; Volume 28; Issue 10; Pages: 4199

مصطلحات موضوعية: histamine H 4 receptor, biased signalling, anti-inflammatory activity, analgesic activity, antipruritic activity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28104199

الاتاحة: https://doi.org/10.3390/molecules28104199

المؤلفون: Dorota Łażewska, Maria Kaleta, Paula Zaręba, Justyna Godyń, Mariam Dubiel, Ewelina Honkisz-Orzechowska, Agata Doroz-Płonka, Anna Więckowska, Holger Stark, Katarzyna Kieć-Kononowicz

المصدر: Molecules; Volume 28; Issue 5; Pages: 2349

مصطلحات موضوعية: histamine H 3 receptor ligand, cholinesterase inhibitor, kinetic studies, toxicity, HepG2 lines, SH-SY5Y lines

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioorganic Chemistry; https://dx.doi.org/10.3390/molecules28052349

الاتاحة: https://doi.org/10.3390/molecules28052349

المؤلفون: Dorota Łażewska, Małgorzata Więcek, Grzegorz Satała, Paulina Chałupnik, Ewa Żesławska, Ewelina Honkisz-Orzechowska, Monika Tarasek, Gniewomir Latacz, Wojciech Nitek, Ewa Szymańska, Jadwiga Handzlik

المصدر: Molecules; Volume 28; Issue 3; Pages: 1108

مصطلحات موضوعية: serotonin 5-HT 6 receptor, 5-HT 6 R ligands, 1,3,5-triazine derivatives, solubility, crystal structure

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28031108

الاتاحة: https://doi.org/10.3390/molecules28031108

المؤلفون: Sabrina Garbo, Silvia Di Giacomo, Dorota Łażewska, Ewelina Honkisz-Orzechowska, Antonella Di Sotto, Rossella Fioravanti, Clemens Zwergel, Cecilia Battistelli

المصدر: Pharmaceutics; Volume 15; Issue 1; Pages: 104

مصطلحات موضوعية: selenium, cancer, cancer therapy, immunotherapy, small organic Se-containing compounds, Se-nanoparticles

وصف الملف: application/pdf

Relation: Drug Targeting and Design; https://dx.doi.org/10.3390/pharmaceutics15010104

الاتاحة: https://doi.org/10.3390/pharmaceutics15010104

المؤلفون: Dorota Łażewska, Agata Siwek, Agnieszka Olejarz-Maciej, Agata Doroz-Płonka, Anna Wiktorowska-Owczarek, Marta Jóźwiak-Bębenista, David Reiner-Link, Annika Frank, Wioletta Sromek-Trzaskowska, Ewelina Honkisz-Orzechowska, Ewelina Królicka, Holger Stark, Marek Wieczorek, Waldemar Wagner, Katarzyna Kieć-Kononowicz, Anna Stasiak

المصدر: Pharmaceutics; Volume 14; Issue 10; Pages: 2187

مصطلحات موضوعية: histamine H 3 receptor, histamine H 3 receptor ligand, monoamine oxidase B (MAO B), MAO B inhibitor, dual-target ligands, pitolisant, in vivo studies

وصف الملف: application/pdf

Relation: Drug Targeting and Design; https://dx.doi.org/10.3390/pharmaceutics14102187

الاتاحة: https://doi.org/10.3390/pharmaceutics14102187

المؤلفون: Gniewomir Latacz, Kinga Sałat, Anna Furgała-Wojas, Adrian Martyniak, Agnieszka Olejarz-Maciej, Ewelina Honkisz-Orzechowska, Ewa Szymańska

المصدر: Molecules; Volume 27; Issue 3; Pages: 875

مصطلحات موضوعية: AMPA antagonist, phenylalanine, neuroprotection, antioxidant activity, FRAP, ORAC-FL, MAO-B inhibition, anticonvulsant activity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioorganic Chemistry; https://dx.doi.org/10.3390/molecules27030875

الاتاحة: https://doi.org/10.3390/molecules27030875

المؤلفون: Sylwia Sudoł, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Ewelina Honkisz-Orzechowska, Barbara Mordyl, Natalia Wilczyńska-Zawal, Grzegorz Satała, Katarzyna Kucwaj-Brysz, Anna Partyka, Gniewomir Latacz, Agnieszka Olejarz-Maciej, Anna Wesołowska, Jadwiga Handzlik

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 19; Pages: 10773

مصطلحات موضوعية: 5-HT 6 ligands, 1,3,5-triazine, ADME-Tox parameters, procognitive effects, Alzheimer’s disease

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms221910773

الاتاحة: https://doi.org/10.3390/ijms221910773

المؤلفون: Ewelina Honkisz-Orzechowska, Katarzyna Popiołek-Barczyk, Zuzanna Linart, Jadwiga Filipek-Gorzała, Anna Rudnicka, Agata Siwek, Tobias Werner, Holger Stark, Jakub Chwastek, Katarzyna Starowicz, Katarzyna Kieć-Kononowicz, Dorota Łażewska

مصطلحات موضوعية: Pharmacology, Immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ac424a08557620521d417ef1b38124
https://ruj.uj.edu.pl/xmlui/handle/item/304866

المؤلفون: Alaa Alachkar, Dorota Łażewska, Gniewomir Latacz, Annika Frank, Agata Siwek, Annamaria Lubelska, Ewelina Honkisz-Orzechowska, Jadwiga Handzlik, Holger Stark, Katarzyna Kieć-Kononowicz, Bassem Sadek

المصدر: International Journal of Molecular Sciences; Volume 19; Issue 11; Pages: 3386

مصطلحات موضوعية: histamine H3 receptors, antagonists, anticonvulsant, maximal electroshock, pentylenetetrazole, strychnine, antiproliferative action, metabolic stability

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms19113386

الاتاحة: https://doi.org/10.3390/ijms19113386

المؤلفون: Ewelina, Honkisz-Orzechowska, Katarzyna, Popiołek-Barczyk, Zuzanna, Linart, Jadwiga, Filipek-Gorzała, Anna, Rudnicka, Agata, Siwek, Tobias, Werner, Holger, Stark, Jakub, Chwastek, Katarzyna, Starowicz, Katarzyna, Kieć-Kononowicz, Dorota, Łażewska

المصدر: Inflammation research : official journal of the European Histamine Research Society ... [et al.].

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::35d031673309b7b3afd6ed997b32ed75
https://pubmed.ncbi.nlm.nih.gov/36370200

المؤلفون: Wesam Ali, Sabrina Garbo, Annamária Kincses, Márta Nové, Gabriella Spengler, Elisabetta Di Bello, Ewelina Honkisz-Orzechowska, Tadeusz Karcz, Ewa Szymańska, Ewa Żesławska, Małgorzata Starek, Monika Dąbrowska, Wojciech Nitek, Katarzyna Kucwaj-Brysz, Patryk Pyka, Rossella Fioravanti, Claus Jacob, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzlik

مصطلحات موضوعية: Pharmacology, 03.03. Egészségtudományok, Lymphoma, Triazines, Organic Chemistry, Antineoplastic Agents, 03.01. Általános orvostudomány, General Medicine, Sulfides, Drug Resistance, Multiple, Neoplasm Proteins, Mice, Pharmaceutical Preparations, Drug Resistance, Neoplasm, Cell Line, Tumor, Drug Discovery, Animals, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 2

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3997da375cd717b517deccce5536b4
https://ruj.uj.edu.pl/xmlui/handle/item/303938

المؤلفون: Tomasz, Wichur, Anna, Pasieka, Justyna, Godyń, Dawid, Panek, Izabella, Góral, Gniewomir, Latacz, Ewelina, Honkisz-Orzechowska, Adam, Bucki, Agata, Siwek, Monika, Głuch-Lutwin, Damijan, Knez, Xavier, Brazzolotto, Stanislav, Gobec, Marcin, Kołaczkowski, Raimon, Sabate, Barbara, Malawska, Anna, Więckowska

المصدر: European journal of medicinal chemistry. 225

مصطلحات موضوعية: Amyloid beta-Peptides, Indoles, Dose-Response Relationship, Drug, Molecular Structure, tau Proteins, Hep G2 Cells, Ligands, Molecular Docking Simulation, Mice, Protein Aggregates, Structure-Activity Relationship, Butyrylcholinesterase, Receptors, Serotonin, Drug Discovery, Electrophorus, Acetylcholinesterase, Microsomes, Liver, Animals, Humans, Cholinesterase Inhibitors, Horses, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::077914f6dc7def7c5c689536d69bdbf6
https://pubmed.ncbi.nlm.nih.gov/34461507

المؤلفون: Justyna, Godyń, Paula, Zaręba, Dorota, Łażewska, Dorota, Stary, David, Reiner-Link, Annika, Frank, Gniewomir, Latacz, Szczepan, Mogilski, Maria, Kaleta, Agata, Doroz-Płonka, Annamaria, Lubelska, Ewelina, Honkisz-Orzechowska, Agnieszka, Olejarz-Maciej, Jadwiga, Handzlik, Holger, Stark, Katarzyna, Kieć-Kononowicz, Barbara, Malawska, Marek, Bajda

المصدر: Bioorganic chemistry. 114

مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Biphenyl Compounds, Ligands, Structure-Activity Relationship, Alzheimer Disease, Butyrylcholinesterase, Electrophorus, Acetylcholinesterase, Animals, Humans, Receptors, Histamine H3, Cholinesterase Inhibitors, Horses, Monoamine Oxidase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e68e231b6213058a056bf9df683473f3
https://pubmed.ncbi.nlm.nih.gov/34217977

المؤلفون: Xavier Brazzolotto, Izabella Góral, Anna Pasieka, Gniewomir Latacz, Anna Więckowska, Adam Bucki, Dawid Panek, Barbara Malawska, Marcin Kołaczkowski, Tomasz Wichur, Raimon Sabaté, Damijan Knez, Monika Głuch-Lutwin, Justyna Godyń, Ewelina Honkisz-Orzechowska, Stanislav Gobec, Agata Siwek

المصدر: European Journal of Medicinal Chemistry. 225:113783

مصطلحات موضوعية: Pharmacology, Indole test, cholinesterase inhibitors, biology, CYP3A4, β-amyloid, Chemistry, Amyloid beta, Organic Chemistry, General Medicine, Alzheimer's disease, In vitro, Biochemistry, Tacrine, multifunctional agents, 5-HT6 antagonists, Drug Discovery, Tau protein, medicine, 5-HT6 receptor, biology.protein, Butyrylcholinesterase, medicine.drug, Cholinesterase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e6511bad0aaf428df90277374a636a
https://doi.org/10.1016/j.ejmech.2021.113783

المؤلفون: Katarzyna Kieć-Kononowicz, Dorota Stary, Ewelina Honkisz-Orzechowska, Agnieszka Olejarz-Maciej, Agata Doroz-Płonka, Marek Bajda, Annamaria Lubelska, Paula Zaręba, Jadwiga Handzlik, Barbara Malawska, Szczepan Mogilski, David Reiner-Link, Annika Frank, Holger Stark, Maria Kaleta, Gniewomir Latacz, Dorota Łażewska, Justyna Godyń

المصدر: Bioorganic Chemistry. 114:105129

مصطلحات موضوعية: cholinesterase inhibitors, Pharmacology, 01 natural sciences, Biochemistry, monoamine oxidase B inhibitors, chemistry.chemical_compound, Drug Discovery, Molecular Biology, IC50, Butyrylcholinesterase, Cholinesterase, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Biological activity, multi-target-directed ligands, Acetylcholinesterase, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, biology.protein, biphenyl derivatives, Monoamine oxidase B, Histamine H3 receptor, Alzheimer’s disease, histamine H3 receptor ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e584eac3bbc506d43ce2aebcb21a6950
https://doi.org/10.1016/j.bioorg.2021.105129