المؤلفون: Kristina Breitenecker, Viola Hedrich, Franziska Pupp, Doris Chen, Eva Řezníčková, Gregor Ortmayr, Heidemarie Huber, Gerhard Weber, Lorenz Balcar, Matthias Pinter, Wolfgang Mikulits

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: hepatocellular carcinoma, GAS6, Axl, tyrosine kinase inhibitors, Regorafenib, ErbB, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1238883/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/c7d00e5156d647469e16c383d6cf5ad0

المؤلفون: Beatričė Razmienė, Eva Řezníčková, Vaida Dambrauskienė, Radek Ostruszka, Martin Kubala, Asta Žukauskaitė, Vladimír Kryštof, Algirdas Šačkus, Eglė Arbačiauskienė

المصدر: Molecules, Vol 26, Iss 21, p 6747 (2021)

مصطلحات موضوعية: antiproliferation, cell death, cross-coupling, cycloiodination, pyrazole, pyridine, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/21/6747; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/c1e5ffbbb6c3420e803de16af82fd513

المؤلفون: Ana Paula Murray, Eva Řezníčková, Natalia Paola Alza, Radek Jorda, Valeria Cavallaro, Vladimír Kryštof

المصدر: Biological and Pharmaceutical Bulletin. 2017, 40(11):1923

المؤلفون: Kristina Breitenecker, Viola Hedrich, Franziska Pupp, Doris Chen, Eva Řezníčková, Gregor Ortmayr, Heidemarie Huber, Gerhard Weber, Lorenz Balcar, Matthias Pinter, Wolfgang Mikulits

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, hepatocellular carcinoma, GAS6, Axl, tyrosine kinase inhibitors, Regorafenib, ErbB, bFGF

Relation: https://figshare.com/articles/presentation/Presentation_1_Synergism_of_the_receptor_tyrosine_kinase_Axl_with_ErbB_receptors_mediates_resistance_to_regorafenib_in_hepatocellular_carcinoma_pptx/24104931

الاتاحة: https://doi.org/10.3389/fonc.2023.1238883.s001
https://figshare.com/articles/presentation/Presentation_1_Synergism_of_the_receptor_tyrosine_kinase_Axl_with_ErbB_receptors_mediates_resistance_to_regorafenib_in_hepatocellular_carcinoma_pptx/24104931

المؤلفون: Markéta Kovalová, Libor Havlíček, Stefan Djukic, Jana Škerlová, Miroslav Peřina, Tomáš Pospíšil, Eva Řezníčková, Pavlína Řezáčová, Radek Jorda, Vladimír Kryštof

المصدر: Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114492- (2023)

مصطلحات موضوعية: Cyclin-dependent kinase 7, pyrazolo[4,3-d]pyrimidine, Selectivity, Inhibitor, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332223002809; https://doaj.org/toc/0753-3322; https://doaj.org/article/ebadbe56eb674ba785bd3c09da68b0d5

الاتاحة: https://doi.org/10.1016/j.biopha.2023.114492
https://doaj.org/article/ebadbe56eb674ba785bd3c09da68b0d5

المؤلفون: Monika Tomanová, Karolína Kozlanská, Radek Jorda, Lukáš Jedinák, Tereza Havlíková, Eva Řezníčková, Miroslav Peřina, Pavel Klener, Alexandra Dolníková, Petr Cankař, Vladimír Kryštof

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16169

مصطلحات موضوعية: FLT3, cyclin-dependent kinase, purine, inhibitor, acute myeloid leukemia

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms232416169

الاتاحة: https://doi.org/10.3390/ijms232416169

المؤلفون: Neetu Dayal (1520278), Eva Řezníčková (1927012), Delmis E. Hernandez (11167597), Miroslav Peřina (6597020), Sandra Torregrosa-Allen (2917700), Bennett D. Elzey (3341810), Jana Škerlová (6597014), Haresh Ajani (2910749), Stefan Djukic (11167600), Veronika Vojáčková (11167603), Martin Lepšík (1265016), Pavlína Řezáčová (1265025), Vladimír Kryštof (1569754), Radek Jorda (1569763), Herman O. Sintim (1309977)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, AML cell lines, Acute Myeloid Leukemia Cells, FLT 3 kinase, compound, quinoline-Based Kinase Inhibitors I., IC 50 values, oncogenic FLT 3-ITD mutations, novel 3 H, kinase inhibitor core, 3 H, FLT 3 inhibitor quizartinib, leukemia, pyrazolo, quinoline-containing, nanomolar IC 50 values, mouse-disseminated AML model

Relation: https://figshare.com/articles/journal_contribution/3_i_H_i_Pyrazolo_4_3_i_f_i_quinoline-Based_Kinase_Inhibitors_Inhibit_the_Proliferation_of_Acute_Myeloid_Leukemia_Cells_In_Vivo/15031702

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00330.s001

المؤلفون: Wolfgang Mikulits, Vladimír Kryštof, Miroslav Strnad, Tomáš Gucký, Marek Zatloukal, Radek Jorda, Walter Berger, Walter Miklos, Hans Rotheneder, Thomas S. Weiss, Eva Řezníčková, Markus Grubinger, Christine Haider

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3c0d4cf0125212de11412147b3a81d
https://doi.org/10.1158/1535-7163.22498968.v1

المؤلفون: Wolfgang Mikulits, Vladimír Kryštof, Miroslav Strnad, Tomáš Gucký, Marek Zatloukal, Radek Jorda, Walter Berger, Walter Miklos, Hans Rotheneder, Thomas S. Weiss, Eva Řezníčková, Markus Grubinger, Christine Haider

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf26d254f2c41c95fa32ce8b973d975
https://doi.org/10.1158/1535-7163.22498959.v1

المؤلفون: Wolfgang Mikulits, Vladimír Kryštof, Miroslav Strnad, Tomáš Gucký, Marek Zatloukal, Radek Jorda, Walter Berger, Walter Miklos, Hans Rotheneder, Thomas S. Weiss, Eva Řezníčková, Markus Grubinger, Christine Haider

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabad803bebde6f2c8a448dab86a2a3d
https://doi.org/10.1158/1535-7163.22498962

المؤلفون: Wolfgang Mikulits, Vladimír Kryštof, Miroslav Strnad, Tomáš Gucký, Marek Zatloukal, Radek Jorda, Walter Berger, Walter Miklos, Hans Rotheneder, Thomas S. Weiss, Eva Řezníčková, Markus Grubinger, Christine Haider

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2955e3c3011effd76ec65a2c3d23da
https://doi.org/10.1158/1535-7163.22498956.v1

المؤلفون: Wolfgang Mikulits, Vladimír Kryštof, Miroslav Strnad, Tomáš Gucký, Marek Zatloukal, Radek Jorda, Walter Berger, Walter Miklos, Hans Rotheneder, Thomas S. Weiss, Eva Řezníčková, Markus Grubinger, Christine Haider

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752cdce85ead9afc9caf05d4c0fe7dd3
https://doi.org/10.1158/1535-7163.22498965.v1

المؤلفون: Hana Dostálová, Radek Jorda, Eva Řezníčková, Vladimír Kryštof

مصطلحات موضوعية: Pharmacology, Oncology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380048841ad736572c23d6ccfdfaf0d8
https://doi.org/10.1101/2023.02.23.529815

المؤلفون: Kristina Breitenecker, Viola Hedrich, Franziska Pupp, Doris Chen, Eva Řezníčková, Gregor Ortmayr, Heidemarie Huber, Gerhard Weber, Lorenz Balcar, Matthias Pinter, Wolfgang Mikulits

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, hepatocellular carcinoma, GAS6, Axl, tyrosine kinase inhibitors, Regorafenib, ErbB, bFGF

Relation: https://figshare.com/articles/dataset/Table_1_Synergism_of_the_receptor_tyrosine_kinase_Axl_with_ErbB_receptors_mediates_resistance_to_regorafenib_in_hepatocellular_carcinoma_docx/24104934

الاتاحة: https://doi.org/10.3389/fonc.2023.1238883.s002
https://figshare.com/articles/dataset/Table_1_Synergism_of_the_receptor_tyrosine_kinase_Axl_with_ErbB_receptors_mediates_resistance_to_regorafenib_in_hepatocellular_carcinoma_docx/24104934

المؤلفون: Haresh Ajani, Miroslav Peřina, Radek Jorda, Delmis E. Hernandez, Pavlína Řezáčová, Stefan Djukic, Neetu Dayal, Martin Lepšík, Eva Řezníčková, Veronika Vojáčková, Jana Škerlová, Sandra E. Torregrosa-Allen, Bennett D. Elzey, Vladimír Kryštof, Herman O. Sintim

المصدر: Journal of Medicinal Chemistry. 64:10981-10996

مصطلحات موضوعية: Kinase, Chemistry, Myeloid leukemia, medicine.disease, In vitro, chemistry.chemical_compound, Leukemia, Docking (molecular), Cell culture, hemic and lymphatic diseases, Drug Discovery, Cancer research, medicine, Molecular Medicine, FLT3 Inhibitor, Quizartinib

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c40f35a27294ccda9206f652f5548d75
https://doi.org/10.1021/acs.jmedchem.1c00330

المؤلفون: Kristýna Vlková, Růžena Padrtová, Tomáš Gucký, Miroslav Peřina, Eva Řezníčková, Vladimír Kryštof

المصدر: Bioorganic & Medicinal Chemistry Letters. 80:129096

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640dca68144abfacce1d8813ece67700
https://doi.org/10.1016/j.bmcl.2022.129096

المؤلفون: Eva Řezníčková, Soňa Krajčovičová, Miroslav Peřina, Markéta Kovalová, Miroslav Soural, Vladimír Kryštof

المصدر: European Journal of Medicinal Chemistry. 243:114792

مصطلحات موضوعية: Pharmacology, History, Polymers and Plastics, Organic Chemistry, Apoptosis, General Medicine, Cyclin-Dependent Kinase 9, Industrial and Manufacturing Engineering, Leukemia, Myeloid, Acute, fms-Like Tyrosine Kinase 3, Mutation, Proteolysis, Drug Discovery, Humans, Business and International Management, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e71983ff56fa5370589c51fe861f75b
https://doi.org/10.1016/j.ejmech.2022.114792

المؤلفون: Martin Porubský, Eva Řezníčková, Soňa Křupková, Vladimír Kryštof, Jan Hlaváč

المصدر: Bioorganic Chemistry. 129:106151

مصطلحات موضوعية: Enzyme Activation, Caspase 8, Organic Chemistry, Drug Discovery, Fluorescence Resonance Energy Transfer, Apoptosis, Molecular Biology, Biochemistry, Caspase 9, Fluorescent Dyes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae25f5470a8b7df49eb496e7f65431d9
https://doi.org/10.1016/j.bioorg.2022.106151

المؤلفون: Kristýna Vlková, Tomáš Gucký, Miroslav Peřina, Eva Řezníčková, Vladimír Kryštof

المصدر: Bioorganicmedicinal chemistry letters. 60

مصطلحات موضوعية: Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Cell Cycle Checkpoints, Biochemistry, Structure-Activity Relationship, Purines, Cell Line, Tumor, Drug Discovery, Molecular Medicine, Humans, Drug Screening Assays, Antitumor, Molecular Biology, Protein Kinase Inhibitors, Protein Kinases, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b02863784aa8adbbd7298d9a102961a
https://pubmed.ncbi.nlm.nih.gov/35124201

المؤلفون: Eva Řezníčková, Václav Bazgier, Urszula Kiełczewska, Radek Jorda, Jacek W. Morzycki, Lucie Rárová, Agnieszka Wojtkielewicz, Leszek Siergiejczyk, Jadwiga Maj, Karel Berka

المصدر: European Journal of Medicinal Chemistry. 179:483-492

مصطلحات موضوعية: Male, Galeterone, Cell Survival, medicine.medical_treatment, Antineoplastic Agents, 01 natural sciences, Cell Line, Steroid, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, Transcription (biology), Prostate, Drug Discovery, medicine, Humans, Cell Proliferation, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Prostatic Neoplasms, General Medicine, medicine.disease, In vitro, 0104 chemical sciences, Androstadienes, Androgen receptor, medicine.anatomical_structure, Docking (molecular), PC-3 Cells, Cancer research, Benzimidazoles, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bc86e4288760383580647699a830e0
https://doi.org/10.1016/j.ejmech.2019.06.040