المؤلفون: Ibragim Gaidarov, H. Kiyomi Komori, Dariusz T. Stepniak, Karin Bruinsma, Huong Dang, Xiaohua Chen, Todd Anthony, Joel Gatlin, Lisa Karimi‐Naser, Anh‐Tuan Ton, Tim Indersmitten, Paul E. Miller, Andre Ghetti, Najah Abi‐Gerges, David Unett, Hussien Al‐Shamma, Christopher J. Rabbat, Catherine Crosby, John W. Adams

المصدر: FEBS Open Bio, Vol 15, Iss 1, Pp 108-121 (2025)

مصطلحات موضوعية: etrasimod, pharmacodynamics, pharmacokinetics, sphingosine 1‐phosphate receptor modulator, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2211-5463

URL الوصول: https://doaj.org/article/cf79b53711654d2c96b13570cbd1bd08

المؤلفون: Kushal Seni, Aniket Saini, Rabin Debnath, Arshdeep Singh, Anjali Sharma, Deepak Singh Bisht, Viney Chawla, Pooja A Chawla

المصدر: Health Sciences Review, Vol 12, Iss , Pp 100196- (2024)

مصطلحات موضوعية: Ulcerative colitis, Etrasimod, Mechanism of action, Pharmacokinetic, FDA approval, Medicine

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772632024000497; https://doaj.org/toc/2772-6320

URL الوصول: https://doaj.org/article/f3b2b01692c74af4bf6e9f8dbcd48095

المؤلفون: Jingyue Qiu, Jiakuo Liu, Kexin Cai, Ting Xu, Wenwen Liu, Fei Lin, Ning Shi

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: S1PR modulator, etrasimod, ulcerative colitis, auto-immune disease, meta-analysis, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1420455/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/33a91b12b72a4e84aad5c47f954af0a2

المؤلفون: Mohammed S. Alasmari, Faleh Alqahtani, Fawaz Alasmari, Abdullah Alsultan

المصدر: Pharmaceutics, Vol 16, Iss 12, p 1540 (2024)

مصطلحات موضوعية: PBPK, etrasimod, liver impairment, precision dosing, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/12/1540; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/29f5466c1d6547d9978aa5a6d48280c0

المؤلفون: Jelena Kovačić, Daniela Amidžić Klarić, Nikša Turk, Željko Krznarić, Ana Mornar

المصدر: Heliyon, Vol 10, Iss 13, Pp e34066- (2024)

مصطلحات موضوعية: Etrasimod, Forced degradation study, Stability-indicating method, Green chemistry, Mass spectrometry, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024100977; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/b2a2d054d6db43dbaf377f40f305a1e8

المؤلفون: Matt Shirley

مصطلحات موضوعية: Medicine, etrasimod, Velsipity, ulcerative colitis (uc), review, Adis Insight Report

Relation: https://figshare.com/articles/online_resource/Etrasimod_First_Approval/24858873

الاتاحة: https://doi.org/10.6084/m9.figshare.24858873.v1
https://figshare.com/articles/online_resource/Etrasimod_First_Approval/24858873

المؤلفون: Chieh-Yu Liao, Fanta Barrow, Nanditha Venkatesan, Yasuhiko Nakao, Amy S. Mauer, Gavin Fredrickson, Myeong Jun Song, Tejasav S. Sehrawat, Debanjali Dasgupta, Rondell P. Graham, Xavier S. Revelo, Harmeet Malhi

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: lipotoxicity, fatty liver, sphingolipids, Etrasimod, Amiselimod, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1130184/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/04fb835c59e14dc881c914ebb1555452

المؤلفون: Zore, Matej, San-Martin-Galindo, Paola, Reigada, Inés, Hanski, Leena, Fallarero, Adyary, Yli-Kauhaluoma, Jari, Patel, Jayendra

المساهمون: Division of Pharmaceutical Chemistry and Technology, Bioactivity Screening Group, Pharmaceutical Design and Discovery group, Division of Pharmaceutical Biosciences, Anti-infectives research, The Academic Outreach Network, Helsinki One Health (HOH), Divisions of Faculty of Pharmacy, Drug Research Program, Explorations of Anti Infectives, Jari Yli-Kauhaluoma / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: Antibacterial activity, Derivatives, Etrasimod, Mrsa, Staphylococcus aureus, Pharmacy

وصف الملف: application/pdf

Relation: This work was supported by the Academy of Finland (grant numbers 307464, 322724, 324177, and 333291), the Finnish National Agency for Education (grant number TM-18-11021), and Jane and Aatos Erkko Foundation (Project: ABC-Health) . M.Z. would like to acknowledge financial support from Orion Research Foundation Sr.; Zore , M , San-Martin-Galindo , P , Reigada , I , Hanski , L , Fallarero , A , Yli-Kauhaluoma , J & Patel , J 2024 , ' Design and synthesis of etrasimod derivatives as potent antibacterial agents against Gram-positive bacteria ' , European Journal of Medicinal Chemistry , vol. 263 , 115921 . https://doi.org/10.1016/j.ejmech.2023.115921; ORCID: /0000-0003-0370-7653/work/150699482; ORCID: /0000-0002-7742-6363/work/150740780; ORCID: /0000-0002-2562-1888/work/150742318; ORCID: /0000-0002-3121-8542/work/150754771; ORCID: /0000-0003-4799-2011/work/152353256; http://hdl.handle.net/10138/569004; 51f7ae73-a08f-480c-ae83-9c53ead8651a; 001115077500001

الاتاحة: http://hdl.handle.net/10138/569004

المؤلفون: Sarah Bencardino, Ferdinando D’Amico, Ilaria Faggiani, Francesca Bernardi, Mariangela Allocca, Federica Furfaro, Tommaso Lorenzo Parigi, Alessandra Zilli, Gionata Fiorino, Laurent Peyrin-Biroulet, Silvio Danese

المصدر: Journal of Clinical Medicine; Volume 12; Issue 15; Pages: 5014

مصطلحات موضوعية: ulcerative colitis, inflammatory bowel disease, S1P1 receptor modulators, ozanimod, etrasimod, VTX-002, IBD

وصف الملف: application/pdf

Relation: Gastroenterology & Hepatopancreatobiliary Medicine; https://dx.doi.org/10.3390/jcm12155014

الاتاحة: https://doi.org/10.3390/jcm12155014

المؤلفون: Matej Zore, Shella Gilbert-Girard, Paola San-Martin-Galindo, Inés Reigada, Leena Hanski, Kirsi Savijoki, Adyary Fallarero, Jari Yli-Kauhaluoma, Jayendra Z. Patel

المصدر: Frontiers in Microbiology, Vol 13 (2022)

مصطلحات موضوعية: etrasimod, sphingosine-1-phosphate receptor modulators, repurposing, antimicrobials, biofilms, Staphylococcus aureus, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2022.926170/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/863128ab111b49538518df718cd32432

المؤلفون: Zore, Matej, Gilbert-Girard, Shella, San-Martin-Galindo, Paola, Reigada, Inés, Hanski, Leena, Savijoki, Kirsi, Fallarero, Adyary, Yli-Kauhaluoma, Jari, Patel, Jayendra

المساهمون: Division of Pharmaceutical Chemistry and Technology, Pharmaceutical Design and Discovery group, Divisions of Faculty of Pharmacy, Bioactivity Screening Group, Division of Pharmaceutical Biosciences, The Academic Outreach Network, Helsinki One Health (HOH), Drug Research Program, Explorations of Anti Infectives, Faculty of Pharmacy, Anti-infectives research, Department of Food and Nutrition, Jari Yli-Kauhaluoma / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: BIOFILMS, EFFICACY, Gram-positive bacteria, RESISTANCE, SAFETY, SUSCEPTIBILITY, Staphylococcus aureus, antimicrobials, etrasimod, repurposing, sphingosine-1-phosphate receptor modulators, 11832 Microbiology and virology, Pharmacy

وصف الملف: application/pdf

Relation: Zore , M , Gilbert-Girard , S , San-Martin-Galindo , P , Reigada , I , Hanski , L , Savijoki , K , Fallarero , A , Yli-Kauhaluoma , J & Patel , J 2022 , ' Repurposing the Sphingosine-1-Phosphate Receptor Modulator Etrasimod as an Antibacterial Agent Against Gram-Positive Bacteria ' , Frontiers in Microbiology , vol. 13 , 926170 . https://doi.org/10.3389/fmicb.2022.926170; ORCID: /0000-0003-0370-7653/work/115592619; ORCID: /0000-0002-3121-8542/work/115593231; ORCID: /0000-0002-7742-6363/work/115596186; ORCID: /0000-0002-2562-1888/work/115596495; ORCID: /0000-0003-2338-5698/work/115596697; ORCID: /0000-0003-4799-2011/work/152353252; http://hdl.handle.net/10138/345850; 427c6efe-4ab2-4793-ab83-6059a6b8dab2; 000813209600001

الاتاحة: http://hdl.handle.net/10138/345850

المؤلفون: Yarur, Andres J, Chiorean, Michael, Panés, Julián, Jairath, Vipul, Zhang, Jinkun, Rabbat, Christopher J, Sandborn, William J, Vermeire, Séverine, Peyrin-Biroulet, Laurent

المصدر: Articles, Abstracts, and Reports

مصطلحات موضوعية: S1P receptor modulator, endoscopic improvement-histologic remission, etrasimod, mucosal healing, ulcerative colitis. swedish, washington, Gastroenterology

Relation: https://digitalcommons.providence.org/publications/8467; https://www.ncbi.nlm.nih.gov/pubmed/38245818

الاتاحة: https://digitalcommons.providence.org/publications/8467
https://www.ncbi.nlm.nih.gov/pubmed/38245818

المؤلفون: Turk, Nikša, Kovačić, Jelena, Jeličić, Mario-Livio, Amidzic Klarić, Daniela, Krznarić, Željko, Mornar, Ana

مصطلحات موضوعية: IBD, etrasimod, green analytical chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::776ef1f33fdc20451e40501527253796
https://www.bib.irb.hr/1268665

المؤلفون: Cesarec, Vanja

مصطلحات موضوعية: etrasimod, ulcerozni kolitis, HPLC, validacija, AGREE kalkulator

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::40dc3fbb46514c54b1258c3bd9ba0c93
https://www.bib.irb.hr/1281603

المؤلفون: Chieh-Yu Liao, Fanta Barrow, Nanditha Venkatesan, Yasuhiko Nakao, Amy S. Mauer, Gavin Fredrickson, Myeong Jun Song, Tejasav S. Sehrawat, Debanjali Dasgupta, Rondell P. Graham, Xavier S. Revelo, Harmeet Malhi

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, lipotoxicity, fatty liver, sphingolipids, Etrasimod, Amiselimod

Relation: https://figshare.com/articles/figure/Image_1_Modulating_sphingosine_1-phosphate_receptor_signaling_skews_intrahepatic_leukocytes_and_attenuates_murine_nonalcoholic_steatohepatitis_tiff/22671790

الاتاحة: https://doi.org/10.3389/fimmu.2023.1130184.s001
https://figshare.com/articles/figure/Image_1_Modulating_sphingosine_1-phosphate_receptor_signaling_skews_intrahepatic_leukocytes_and_attenuates_murine_nonalcoholic_steatohepatitis_tiff/22671790

المؤلفون: Jurij Hanzel, Melanie S. Hulshoff, Joep Grootjans, Geert D’Haens

المصدر: Expert review of clinical immunology. 18(5)

مصطلحات موضوعية: filgotinib, Etrasimod, Immunology, ozanimod, Interleukin-23, upadacitinib, guselkumab, inflammatory bowel disease, Immunology and Allergy, Humans, Janus Kinase Inhibitors, mirikizumab, Colitis, Ulcerative, ulcerative colitis, Janus Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957ff6177913571edd0ca3d216479257
https://pubmed.ncbi.nlm.nih.gov/35477319

المؤلفون: Kovačić, Jelena, Jeličić, Mario-Livio, Amidžić Klarić, Daniela, Nigović, Biljana, Mužina, Katarina, Kurajica, Stanislav, Turk, Nikša, Jelaković, Mislav, Krznarić, Željko, Mornar, Ana

المساهمون: Šakić, Davor, Pavić, Kristina

مصطلحات موضوعية: rizik, etrasimod, CACD

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::e25f381e29d4aa5b2601e3150b678d49
https://www.bib.irb.hr/1225862

المؤلفون: Julián Panés, Michael Chiorean, Krisztina Lazin, Snehal Naik, Bruce E. Sands, Severine Vermeire, Christopher H Cabell, Jinkun Zhang, Preston Klassen, Laurent Peyrin-Biroulet, William J. Sandborn

المصدر: Journal of Crohn's & Colitis

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Randomization, Indoles, Medication Therapy Management, Etrasimod, Dose-Response Relationship, Immunologic, Long Term Adverse Effects, Acetates, Placebo, Endoscopy, Gastrointestinal, Eccojc/1040, Gastrointestinal Agents, Internal medicine, long-term extension study, Medicine, Humans, Adverse effect, Sphingosine-1-Phosphate Receptors, AcademicSubjects/MED00260, medicine.diagnostic_test, Drug Tapering, business.industry, Remission Induction, Gastroenterology, General Medicine, Original Articles, etrasimod, medicine.disease, Ulcerative colitis, Endoscopy, Safety profile, Treatment Outcome, Colitis, Ulcerative, Female, Long term safety, Open label, Drug Monitoring, business, Long-term extension study

وصف الملف: Print

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9603e53aa02975506bfbd1bb1d9bc2f4
https://pubmed.ncbi.nlm.nih.gov/33475734

المؤلفون: Matej Zore, Shella Gilbert-Girard, Paola San-Martin-Galindo, Inés Reigada, Leena Hanski, Kirsi Savijoki, Adyary Fallarero, Jari Yli-Kauhaluoma, Jayendra Z. Patel

مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, etrasimod, sphingosine-1-phosphate receptor modulators, repurposing, antimicrobials, biofilms, Staphylococcus aureus, Gram-positive bacteria

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Repurposing_the_Sphingosine-1-Phosphate_Receptor_Modulator_Etrasimod_as_an_Antibacterial_Agent_Against_Gram-Positive_Bacteria_docx/20002448

الاتاحة: https://doi.org/10.3389/fmicb.2022.926170.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Repurposing_the_Sphingosine-1-Phosphate_Receptor_Modulator_Etrasimod_as_an_Antibacterial_Agent_Against_Gram-Positive_Bacteria_docx/20002448

المؤلفون: Vermeire, Séverine, Chiorean, Michael, Panés, Julián, Peyrin-Biroulet, Laurent, Zhang, Jinkun, Sands, Bruce, Lazin, Krisztina, Klassen, Preston, Naik, Snehal, Cabell, Christopher, Sandborn, William

المساهمون: University Hospitals Leuven Leuven, Virginia Mason Medical Center, Clinic Barcelona Hospital Universitari, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Service d'Hépato-gastro-entérologie CHRU Nancy, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), ARENA Pharmaceuticals, Icahn School of Medicine at Mount Sinai New York (MSSM), University of California San Diego (UC San Diego), University of California (UC)

المصدر: ISSN: 1873-9946.

مصطلحات موضوعية: Ulcerative colitis, etrasimod, long-term extension study, MESH: Acetates, MESH: Adult, MESH: Indoles, MESH: Long Term Adverse Effects, MESH: Male, MESH: Medication Therapy Management, MESH: Remission Induction, MESH: Sphingosine-1-Phosphate Receptors, MESH: Treatment Outcome, MESH: Colitis, Ulcerative, MESH: Dose-Response Relationship, Immunologic, MESH: Drug Monitoring, MESH: Drug Tapering, MESH: Endoscopy, Gastrointestinal, MESH: Female, MESH: Gastrointestinal Agents, MESH: Humans, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/33475734; PUBMED: 33475734; PUBMEDCENTRAL: PMC8218705

الاتاحة: https://hal.univ-lorraine.fr/hal-04214574
https://doi.org/10.1093/ecco-jcc/jjab016