المؤلفون: Eric S. Nisenbaum, Thomas E. Salt, S.A. Neale, Caroline S. Copeland

المصدر: British Journal of Pharmacology. 179:1607-1619

مصطلحات موضوعية: Pharmacology, Agonist, Thalamic reticular nucleus, Allosteric modulator, Chemistry, medicine.drug_class, Thalamus, Glutamate receptor, Metabotropic receptor, medicine.anatomical_structure, Metabotropic glutamate receptor, medicine, Receptor, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f41892c318fde2875b78703fd6e11db1
https://doi.org/10.1111/bph.15640

المؤلفون: Paul L. Ornstein, David S. Bredt, Vanessa N. Barth, Eric S. Nisenbaum, Kar-Chan Choong, Wenhong Guo, Warren J. Porter, Kevin Matthew Gardinier, Emanuele Sher, Yue-Wei Qian, Jon K. Reel, Christian C. Felder, John T. Catlow, Rosa Maria A. Simmons, Kevin D. Burris, Kelly L. Knopp, Douglas Linn Gernert, Chunjin Ding, Steven Swanson, Anne B. Need, Theron M. Wall, He Wang, Akihiko Kato, Douglas A. Schober, Ruud Zwart, Benjamin L. Adams, Jeffrey M. Witkin

المصدر: Journal of Pharmacology and Experimental Therapeutics. 369:345-363

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Chemistry, Central nervous system, Glutamate receptor, Stimulation, AMPA receptor, Somatosensory system, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, nervous system, Synaptic plasticity, Excitatory postsynaptic potential, medicine, Molecular Medicine, Receptor, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0a148f5b308f73f0b2bd16ea57df7708
https://doi.org/10.1124/jpet.118.250126

المؤلفون: Caroline S, Copeland, Stuart A, Neale, Eric S, Nisenbaum, Thomas E, Salt

المصدر: British journal of pharmacologyREFERENCES. 179(8)

مصطلحات موضوعية: Mice, Knockout, Neurons, Mice, Thalamus, Animals, Glutamic Acid, Receptors, Metabotropic Glutamate, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e188d41d4abe7c9c0ee4f10dde1b6344
https://pubmed.ncbi.nlm.nih.gov/34355803

المؤلفون: Jeffrey L. Krajewski, Jeff S. McDermott, Xiaoming Jin, Theodore R. Cummins, Xingjie Ping, Shaun R. Patel, Eric S. Nisenbaum, Reesha R. Patel, Xian Xuan Chi

مصطلحات موضوعية: Gene isoform, Chemistry, Sodium channel, NAV1, HEK 293 cells, Ictal, Patch clamp, Local field potential, Inhibitory postsynaptic potential, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41f119a29b46482a4120d0997288620e
https://doi.org/10.1101/2020.05.29.124693

المؤلفون: Kojun Tsuji, Marian Kollarik, Qi Liu, Makoto Inoue, Jeff S. McDermott, Nikoleta Pavelkova, Takanori Tsujimura, Bradley J. Undem, Jeff Krajewski, Li Yu, Eric S. Nisenbaum, Brendan J. Canning, Sonya Meeker, Izumi Ujihara

المصدر: European Journal of Pharmacology. 907:174192

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, business.industry, Sodium channel, Ambroxol, Motility, Blockade, Guinea pig, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Blood pressure, Control of respiration, medicine, Respiratory system, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83f3b8670a3b717e295852cbb275c051
https://doi.org/10.1016/j.ejphar.2021.174192

المؤلفون: Dominic L. Li, Mark A. Muhlhauser, Denise Morrow, Lijuan Yang, James A. Monn, Michael P. Johnson, Kelly L. Knopp, Rosa Maria A. Simmons, Steven Swanson, Beth M. Forster, Eric S. Nisenbaum, Jeffrey D. Kennedy

المصدر: British Journal of Pharmacology. 174:822-835

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Agonist, business.industry, medicine.drug_class, Chronic pain, Visceral pain, Receptor antagonist, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Nociception, Allodynia, Metabotropic receptor, Hyperalgesia, Medicine, medicine.symptom, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::695acf8d9210d1c7b441e8cf3e534bb9
https://doi.org/10.1111/bph.13740

المؤلفون: Kelly L. Knopp, Akihiko Kato, Michael P. Johnson, Jeff S. McDermott, Theron M. Wall, Benjamin L. Adams, Eric S. Nisenbaum

المصدر: SATURDAY, 15 JUNE 2019.

مصطلحات موضوعية: 030203 arthritis & rheumatology, 0301 basic medicine, Oncology, medicine.medical_specialty, Baricitinib, business.industry, Chronic pain, Osteoarthritis, Plasma levels, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Joint mobility, Internal medicine, Rheumatoid arthritis, Joint pain, medicine, Tramadol, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f9482d744886ff4ba022d083b1363ab0
https://doi.org/10.1136/annrheumdis-2019-eular.1751

المؤلفون: Christian C. Felder, Ed Siuda, Chuanxi Xiang, Hongling Xiao, James A. Monn, Lourdes Prieto, Anne T. Quets, David L. McKinzie, Beverly A. Heinz, Marla L. Watt, Douglas A. Schober, Yuan Tu, Eric S. Nisenbaum

المصدر: Journal of Pharmacology and Experimental Therapeutics. 361:190-197

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, Pharmacology, Biology, Receptors, Metabotropic Glutamate, Partial agonist, Rats, Sprague-Dawley, Translational Research, Biomedical, Bridged Bicyclo Compounds, Mice, 03 medical and health sciences, 0302 clinical medicine, Excitatory Amino Acid Agonists, medicine, Animals, Humans, Inverse agonist, Receptor, Mice, Knockout, Dose-Response Relationship, Drug, Glutamate receptor, Brain, Triazoles, Rats, Drug Partial Agonism, 030104 developmental biology, Metabotropic receptor, Molecular Medicine, Signal transduction, 030217 neurology & neurosurgery, Endogenous agonist, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf1c55697faf52f729e7376c25a77a1
https://doi.org/10.1124/jpet.116.237859

المؤلفون: Akihiko Kato, Hong Yu, Stephen M. Fitzjohn, Francesca Pasqui, Thomas E. Fitch, Yue-Wei Qian, Jon K. Reel, Chunjin Ding, Ruud Zwart, He Wang, Keith A. Wafford, Paul L. Ornstein, Kurt Rasmussen, Matthew Lee, John T.R. Isaac, Kevin D. Burris, Scott D. Gleason, Warren J. Porter, David S. Bredt, Douglas A. Schober, John T. Catlow, Jeffrey M. Witkin, Beverly A. Heinz, Kevin Matthew Gardinier, Emanuele Sher, Douglas Linn Gernert, Yuan Tu, Eric S. Nisenbaum

المصدر: Nature Medicine. 22:1496-1501

مصطلحات موضوعية: 0301 basic medicine, Cerebellum, Antagonist, General Medicine, AMPA receptor, Hippocampal formation, Pharmacology, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Perampanel, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, nervous system, chemistry, Forebrain, medicine, Receptor, Long-term depression, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7cc9375065e97d80f12aadd0767c0493
https://doi.org/10.1038/nm.4221

المؤلفون: Kelly L, Knopp, Rosa Maria A, Simmons, Wenhong, Guo, Benjamin L, Adams, Kevin M, Gardinier, Douglas L, Gernert, Paul L, Ornstein, Warren, Porter, Jon, Reel, Chunjin, Ding, He, Wang, Yuewei, Qian, Kevin D, Burris, Anne, Need, Vanessa, Barth, Steven, Swanson, John, Catlow, Jeffrey M, Witkin, Ruud, Zwart, Emanuele, Sher, Kar-Chan, Choong, Theron M, Wall, Douglas, Schober, Christian C, Felder, Akihiko S, Kato, David S, Bredt, Eric S, Nisenbaum

المصدر: The Journal of pharmacology and experimental therapeutics. 369(3)

مصطلحات موضوعية: Male, Nociception, Neuronal Plasticity, Synaptic Transmission, Rats, Rats, Sprague-Dawley, Animals, Pyrazoles, Tissue Distribution, Benzothiazoles, Calcium Channels, Molecular Targeted Therapy, Receptors, AMPA, Chronic Pain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a0442d2d88bd4a44909afda3d2015420
https://pubmed.ncbi.nlm.nih.gov/30910921

المؤلفون: Andrew D. Piekarz, Daniel Ursu, Antoine Fouillet, Xiaofang Huang, Jake F. Watson, Baolin Li, Birgit T. Priest, Eric S. Nisenbaum, Emanuele Sher

المصدر: Molecular Pain

مصطلحات موضوعية: 0301 basic medicine, Dorsum, Male, Sensory Receptor Cells, Sodium channels, Sensory system, Hippocampus, protoxin-II, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, Calcium imaging, Functional expression, Ganglia, Spinal, Animals, dorsal root ganglia neurons, Nav1.7, Chemistry, Sodium channel, NAV1.7 Voltage-Gated Sodium Channel, Anatomy, electrical field stimulation, Electrical field stimulation, Electric Stimulation, Cell biology, calcium imaging, 030104 developmental biology, Anesthesiology and Pain Medicine, NAV1, Molecular Medicine, Calcium, Original Article, Sodium Channel Blockers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2ce0228231c1774da43eecd46b91a6
https://pubmed.ncbi.nlm.nih.gov/29166836

المؤلفون: Matthew Lee, Jeffrey M. Witkin, Yue-Wei Qian, Eric S. Nisenbaum, He Wang, Rebecca A. Wright, Kevin Matthew Gardinier, Douglas A. Schober, Akihiko Kato, Douglas Linn Gernert

المصدر: ACS chemical neuroscience. 8(12)

مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Protein Conformation, Cognitive Neuroscience, Protein subunit, AMPA receptor, Biology, Biochemistry, Hippocampus, Models, Biological, 03 medical and health sciences, Mice, Structure-Activity Relationship, Animals, Homology modeling, Benzothiazoles, Receptors, AMPA, Neurons, Binding Sites, Glutamate receptor, Antagonist, Cell Biology, General Medicine, biology.organism_classification, Cell biology, Molecular Docking Simulation, 030104 developmental biology, Models, Chemical, Forebrain, Pyrazoles, Stargazer, Ionotropic effect, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a881c8fc0ebca345e6a93945cef6170d
https://pubmed.ncbi.nlm.nih.gov/28825787

المؤلفون: David O. Calligaro, Eric S. Nisenbaum, Kory Schuh, Leslie M. Schuh, Mary Jeanne Kallman, Todd M. Durell, Himanshu P. Upadhyaya, Warren K. Bickel, Paula T. Trzepacz, Albert J. Allen, Frank P. Bymaster, Paul J. Emmerson, Clarke David O, Durisala Desaiah

المصدر: Psychopharmacology

مصطلحات موضوعية: medicine.medical_specialty, Nonstimulant, Substance-Related Disorders, Drug-Seeking Behavior, Pharmacology toxicology, Review, Atomoxetine Hydrochloride, Abuse potential, mental disorders, medicine, Atomoxetine (Strattera®), ADHD, Animals, Humans, Attention deficit hyperactivity disorder, Psychiatry, Pharmacology, Norepinephrine Plasma Membrane Transport Proteins, Adrenergic Uptake Inhibitors, Propylamines, Methylphenidate, Atomoxetine, medicine.disease, Receptors, Neurotransmitter, Behavior, Addictive, Attention Deficit Disorder with Hyperactivity, Potential assessment, Psychology, Protein Binding, medicine.drug, Atomoxetine hydrochloride

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abba3e26621f5c5896b55cf76deeab1a
https://doi.org/10.1007/s00213-013-2986-z

المؤلفون: Eric S. Nisenbaum, Kim E. Garbison, Kuklish Steven Lee, A.E. Kingston, Beverly A. Heinz, Lee A. Phebus, Ellen van der Aar, Vanessa N. Barth, Sean P. Hollinshead, Joseph Michael Gruber, Rosa Maria A. Simmons, Linglin Li, Ryan Thomas Backer, Matthew J. Fisher, Steven C. Peters, Smriti Iyengar

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:2514-2517

مصطلحات موضوعية: Clinical Biochemistry, Allosteric regulation, Administration, Oral, Biological Availability, Pain, Pharmaceutical Science, Pharmacology, Receptors, Metabotropic Glutamate, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, Oral administration, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, Pain Measurement, Analgesics, Isothiazole, Metabotropic glutamate receptor 5, Organic Chemistry, Antagonist, Brain, Stereoisomerism, Amides, Rats, Thiazoles, chemistry, Molecular Medicine, Metabotropic glutamate receptor 1, Excitatory Amino Acid Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c3d23b5f16371fd305689799984b9b
https://doi.org/10.1016/j.bmcl.2012.02.003

المؤلفون: Eric S. Nisenbaum, Stephen P. Arneric, Kelly L. Knopp

المصدر: Current Pharmaceutical Biotechnology. 12:1627-1643

مصطلحات موضوعية: Analgesics, medicine.medical_specialty, Pain and suffering, business.industry, Pain, Pharmaceutical Science, Cancer, Disease, medicine.disease, Primary tumor, Quality of life, Tumor progression, Neoplasms, Endophenotype, Quality of Life, medicine, Physical therapy, Animals, Humans, Intensive care medicine, Cancer pain, business, Neuroglia, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5a2f4dd5d820863829e1ccc27f6bed
https://doi.org/10.2174/138920111798357267

المؤلفون: Kathryn M. Partin, Morris Benveniste, Autumn M. Weeks, David E. Timm, Eric S. Nisenbaum

المصدر: Molecular Pharmacology. 80:267-280

مصطلحات موضوعية: Ampakine, CX614, medicine.drug_class, Stereochemistry, Allosteric regulation, AMPA receptor, Crystallography, X-Ray, Protein Structure, Secondary, Structure-Activity Relationship, chemistry.chemical_compound, Protein structure, Allosteric Regulation, Oxazines, medicine, Animals, Humans, Structure–activity relationship, Excitatory Amino Acid Agents, Receptors, AMPA, Pharmacology, Binding Sites, Chemistry, Articles, Protein Structure, Tertiary, Rats, HEK293 Cells, Mechanism of action, Molecular Medicine, Cyclothiazide, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d24126abb9973719c297cd5a040731
https://doi.org/10.1124/mol.110.070243

المؤلفون: Charles Chow, John P. Mayer, Eric S Nisenbaum, Liang Zeng Yan, Emily Rothstein, Junqing Li, Renee Vaughn, Renee Lynch, Deborah McCarty, Kevin L. McKnight, Kirk W. Johnson, Patrick J. B. Edwards, Baolin Li, Amy Clemens-Smith, Jirong Lu, David B. Flora

المصدر: Journal of Peptide Science. 17:383-386

مصطلحات موضوعية: Pharmacology, Agonist, chemistry.chemical_classification, medicine.medical_specialty, medicine.drug_class, Chemistry, Organic Chemistry, Antagonist, Peptide, General Medicine, Calcitonin gene-related peptide, medicine.disease, Biochemistry, Endocrinology, Calcitonin gene-related peptide receptor antagonist, Migraine, Structural Biology, Calcitonin, Internal medicine, Drug Discovery, medicine, Molecular Medicine, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3cdbb51d05816f3c0c0d8be550174cb5
https://doi.org/10.1002/psc.1358

المؤلفون: Jeff S. McDermott, Jeffrey L. Krajewski, Bin Wu, Eric S. Nisenbaum, Theodore R. Cummins, Zhi-Yong Tan, Kelly L. Knopp

المصدر: Molecular Pain. 15:174480691983710

مصطلحات موضوعية: Male, 0301 basic medicine, Extracellular signal-regulated kinases, Action Potentials, Tetrodotoxin, Membrane Potentials, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Dorsal root ganglion, Ganglia, Spinal, Extracellular, medicine, Animals, Extracellular Signal-Regulated MAP Kinases, Bisindolylmaleimide I, Protein Kinase C, Protein kinase C, Chemistry, Kinase, Sodium, Inflammatory pain, Rats, Cell biology, Electrophysiology, 030104 developmental biology, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Molecular Medicine, 030217 neurology & neurosurgery, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeae9109e9d01f713617c3a207d81a6a
https://doi.org/10.1177/1744806919837104

المؤلفون: Giuseppe Battaglia, Xushan Wang, Valeria Bruno, Anna Traficante, Barbara Riozzi, Beverly A. Heinz, Sara Merlo, Maria Laura Giuffrida, Maria Angela Sortino, Milena Cannella, Eric S. Nisenbaum, Ferdinando Nicoletti, Thomas C. Britton, Gemma Molinaro, Filippo Caraci, Agata Copani, Filippo Drago

المصدر: Molecular Pharmacology. 79:618-626

مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, Glutamate receptor, Biology, Receptor antagonist, Neuroprotection, Metabotropic receptor, Metabotropic glutamate receptor, medicine, Molecular Medicine, Receptor, Long-term depression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff6dad4de503022413b113b747983a
https://doi.org/10.1124/mol.110.067488

المؤلفون: Yue-Wei Qian, Susumu Tomita, Edward R. Siuda, Akihiko Kato, Yuan Tu, Hong Yu, Eric S. Nisenbaum, He Wang, David S. Bredt, Martin B. Gill, Michelle T. Ho

المصدر: Neuron. 68:1082-1096

مصطلحات موضوعية: Neuroscience(all), Gating, AMPA receptor, Hippocampal formation, Hippocampus, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Postsynaptic potential, Animals, Humans, Receptors, AMPA, Rats, Wistar, Long-term depression, Cells, Cultured, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Chemistry, General Neuroscience, Glutamate receptor, Membrane Proteins, Synaptic Potentials, Rats, HEK293 Cells, nervous system, Membrane protein, Silent synapse, Calcium Channels, Ion Channel Gating, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42491c3130473dd67f2bb3c146d4478f
https://doi.org/10.1016/j.neuron.2010.11.026