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1Academic Journal
المؤلفون: Weina Fan, Jian Huang, Fanglin Tian, Xin Hong, Kexin Zhu, Yuning Zhan, Xin Li, Xiangyu Wang, Xin Wang, Li Cai, Ying Xing
المصدر: Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)
مصطلحات موضوعية: alternative splicing, cisplatin resistance, DNA repair, ELAVL1, ERCC1, SNRPA, Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2198-3844
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2Conference
المؤلفون: Patrick Treat Paine, Cheyenne Rechsteiner, Francesco Morandini, Gabriela Desdín-Micó, Calida Mrabti, Alberto Parras, Amin Haghani, Robert Brooke, Steve Horvath, Andrei Seluanov, Vera Gorbunova, Alejandro Ocampo
مصطلحات موضوعية: Genetics, Molecular Biology, Cell Physiology, Cell Metabolism, Epigenetics (incl. Genome Methylation and Epigenomics), aging, DNA damage, ercc1, cellular reprogramming, TGFb
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3Academic Journal
المؤلفون: Andrés Barba, Laura López-Vilaró, Malena Ferre, Margarita Majem, Sergio Martinez-Recio, Olga Bell, María J. Arranz, Juliana Salazar, Ivana Sullivan
المصدر: Pharmaceutics, Vol 16, Iss 9, p 1121 (2024)
مصطلحات موضوعية: ERCC1, ERCC2, platinum-based chemotherapy, small cell lung cancer, pharmacogenomics, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Patrick Treat Paine, Cheyenne Rechsteiner, Francesco Morandini, Gabriela Desdín-Micó, Calida Mrabti, Alberto Parras, Amin Haghani, Robert Brooke, Steve Horvath, Andrei Seluanov, Vera Gorbunova, Alejandro Ocampo
المصدر: Frontiers in Aging, Vol 4 (2024)
مصطلحات موضوعية: aging, DNA damage, ercc1, cellular reprogramming, TGFb, Geriatrics, RC952-954.6
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Marc Donald Wilfried Adico, Abdou Azaque Zouré, Herman Karim Sombié, Touwendpoulimdé Isabelle Kiendrebeogo, Soayebo Dabré, Lanyo Jospin Amegnona, Bélélé Siméon Bakyono, Lassina Traoré, Teega‐Wendé Clarisse Ouedraogo, Rogomenoma Alice Ouedraogo, Théodora M. Zohoncon, Albert Théophane Yonli, Bagora Bayala, Hierrhum Aboubacar Bambara, Florencia W. Djigma, Jacques Simpore
المصدر: Molecular Genetics & Genomic Medicine, Vol 11, Iss 4, Pp n/a-n/a (2023)
مصطلحات موضوعية: breast cancer, Burkina Faso, ERCC1, ERCC2, polymorphism, Genetics, QH426-470
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2324-9269
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6Academic Journal
المؤلفون: Pei Du, Guangqing Li, Lu Wu, Minger Huang
المصدر: Frontiers in Immunology, Vol 13 (2023)
مصطلحات موضوعية: ercc1, cervical cancer, cisplatin, survival, mechanism, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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7Academic Journal
المؤلفون: Xiao-Dong Deng, Jian-Lin Ke, Tai-Yu Chen, Qin Gao, Zhuo-Lin Zhao, Wei Zhang, Huan Liu, Ming-Liang Xiang, Li-Zhen Wang, Ying Ma, Yun Liu
المصدر: Frontiers in Neurology, Vol 13 (2023)
مصطلحات موضوعية: ischemic stroke, polymorphism, susceptibility, expression, ERCC1, Neurology. Diseases of the nervous system, RC346-429
وصف الملف: electronic resource
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8Academic Journal
المؤلفون: Dhouha Jamai, Raja Gargouri, Boulbaba Selmi, Abdelmajid Khabir
المصدر: Genes; Volume 14; Issue 7; Pages: 1467
مصطلحات موضوعية: colorectal cancer, MGMT, ERCC1, methylation, relapse, FOLFOX response
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Human Genomics and Genetic Diseases; https://dx.doi.org/10.3390/genes14071467
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9Academic Journal
المؤلفون: Ming-Yii Huang, Yi-Jung Huang, Tian-Lu Cheng, Wun-Ya Jhang, Chien-Chih Ke, Yi-Ting Chen, Shih-Hsun Kuo, I-Ling Lin, Yu-Hsiang Huang, Chih-Hung Chuang
المصدر: Cells; Volume 12; Issue 11; Pages: 1475
مصطلحات موضوعية: 5-FU-based CRT, OXA-based CRT, ERCC1, XPF–ERCC1 blocker, colorectal cancer
وصف الملف: application/pdf
Relation: Cell Microenvironment; https://dx.doi.org/10.3390/cells12111475
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10Academic Journal
المؤلفون: D. S. Fedorinov, V. K. Lyadov, Sh. P. Abdullayev, A. A. Kachanova, R. N. Heydarov, I. A. Shashkov, V. M. Mikhailovich, S. A. Surzhikov, M. A. Lyadova, I. V. Sychev, V. N. Galkin, I. V. Poddubnaya, D. A. Sychev, Д. С. Федоринов, В. К. Лядов, Ш. П. Абдуллаев, А. A. Качанова, Р. Н. Гейдаров, И. А. Шашков, В. М. Михайлович, С. А. Суржиков, М. А. Лядова, И. В. Сычев, В. Н. Галкин, И. В. Поддубная, Д. А. Сычев
المساهمون: The work was conducted with the support of Russian Science Foundation Grant No. 20-75-10158 – Pharmacogenetic and pharmacokinetic approaches to gastrointestinal cancer chemotherapy based on total body composition., Работа проводилась при поддержке гранта Российского научного фонда №20-75-10158 «Фармакогенетические и фармакокинетические подходы к химиотерапии опухолей желудочно-кишечного тракта на основе анализа состава тела».
المصدر: Meditsinskiy sovet = Medical Council; № 18 (2023); 175-184 ; Медицинский Совет; № 18 (2023); 175-184 ; 2658-5790 ; 2079-701X
مصطلحات موضوعية: TYMS, colorectal cancer, pharmacogenetic testing, DPYD, ERCC1, колоректальный рак, фармакогенетическое тестирование
وصف الملف: application/pdf
Relation: https://www.med-sovet.pro/jour/article/view/7850/6971; Каприн АД, Старинский ВВ, Петрова ГВ (ред.). Состояние онкологической помощи населению России в 2018 году. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России; 2019. 236 с. Режим доступа: https://oncology-association.ru/wp-content/uploads/2020/09/sostoyanie_2018.pdf?ysclid=lnis28yzzl945263948.; Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignar D et al. FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study. J Clin Oncol. 2004;22(2):229–237. https://doi.org/10.1200/JCO.2004.05.113.; De Vita F, Orditura M, Matano E, Bianco R, Carlomagno C, Infusino S et al. A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. Br J Cancer. 2005;92(9):1644–1649. https://doi.org/10.1038/sj.bjc.6602573.; Onakpoya IJ, Heneghan CJ, Aronson JK. Worldwide withdrawal of medicinal products because of adverse drug reactions: a systematic review and analysis. Crit Rev Toxicol. 2016;46(6):477–489. https://doi.org/10.3109/10408444.2016.1149452.; Shahnam A, Ridha Z, Wiese MD, Kichenadasse G, Sorich MJ. Pharmacogenetic and ethnicity influence on oxaliplatin therapy for colorectal cancer: a meta-analysis. Pharmacogenomics. 2016;17(15):1725–1732. https://doi.org/10.2217/pgs-2016-0102.; Meulendijks D, Henricks LM, Sonke GS, Deenen MJ, Froehlich TK, Amstutz U et al. Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data. Lancet Oncol. 2015;16(16):1639–1650. https://doi.org/10.1016/S1470-2045(15)00286-7.; Wigle TJ, Medwid S, Ross C, Schwarz UI, Kim RB. DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation. Curr Oncol. 2023;30(1):663–672. https://doi.org/10.3390/curroncol30010051.; Khalil KA, Musallam HS, Hassan MA, Mahmoud IA. Triplet (FOLFOXIRI) Versus Doublet (FOLFOX or FOLFIRI) Regimen as First Line Treatment in Metastatic Colorectal Carcinoma, a Prospective Phase II, Randomized Controlled Trial. Asian Pac J Cancer Prev. 2022;23(10):3421–3429. https://doi.org/10.31557/APJCP.2022.23.10.3421.; Morel A, Boisdron-Celle M, Fey L, Soulie P, Craipeau MC, Traore S, Gamelin E. Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance. Mol Cancer Ther. 2006;5(11):2895–904. https://doi.org/10.1158/1535-7163.MCT-06-0327.; Sissung TM, Cordes L, Peer CJ, Gandhy S, Redman J, Strauss J, Figg WD. Case report: severe toxicity in an African-American patient receiving FOLFOX carrying uncommon allelic variants in DPYD. Pharmacogenomics. 2021;22(2):81–85. https://doi.org/10.2217/pgs-2020-0120.; Božina N, Bilić I, Ganoci L, Šimičević L, Pleština S, Lešnjaković L, Trkulja V. DPYD polymorphisms c.496A>G, c.2194G>A and c.85T>C and risk of severe adverse drug reactions in patients treated with fluoropyrimidine-based protocols. Br J Clin Pharmacol. 2022;88(5):2190–2202. https://doi.org/10.1111/bcp.15144.; Medwid S, Wigle TJ, Kim RB. Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype. Cancer Chemother Pharmacol. 2023;91(1):97–102. https://doi.org/10.1007/s00280-022-04491-7.; Glewis S, Alexander M, Khabib MNH, Brennan A, Lazarakis S, Martin J et al. A systematic review and meta-analysis of toxicity and treatment outcomes with pharmacogenetic-guided dosing compared to standard of care BSA-based fluoropyrimidine dosing. Br J Cancer. 2022;127(1):126–136. https://doi.org/10.1038/s41416-022-01779-6.; Федянин МЮ, Мамедли ЗЗ, Гордеев СС, Ачкасов СИ, Болотина ЛВ, Гладков ОА и др. Злокачественное новообразование ободочной кишки: клинические рекомендации. 2022. Режим доступа: https://cr.minzdrav.gov.ru/schema/396_3.; Van Triest B, Peters GJ. Thymidylate synthase: a target for combination therapy and determinant of chemotherapeutic response in colorectal cancer. Oncology. 1999;57(3):179–194. https://doi.org/10.1159/000012030.; Kawakami K, Omura K, Kanehira E, Watanabe Y. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res. 1999;19(4B):3249–3252. Available at: https://pubmed.ncbi.nlm.nih.gov/10652619.; Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J et al. Role of Genetic and Nongenetic Factors for Fluorouracil Treatment-Related Severe Toxicity: A Prospective Clinical Trial by the German 5-FU Toxicity Study Group. J Clin Oncol. 2008;26(13):2131–2138. https://doi.org/10.1200/JCO.2006.10.4182.; Sohn KJ, Croxford R, Yates Z, Lucock M, Kim YI. Effect of the Methylenetetrahydrofolate Reductase C677T Polymorphism on Chemosensitivity of Colon and Breast Cancer Cells to 5-Fluorouracil and Methotrexate. J Natl Cancer Inst. 2004;96(2):134–144. https://doi.org/10.1093/jnci/djh015.; Ramos-Esquivel A, Chinchilla R, Valle M. Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer. Anticancer Res. 2020;40(8):4263–4270. https://doi.org/10.21873/anticanres.14428.; Xie C, Zhao J, Hua W, Tan P, Chen Y, Rui J et al. Effect of XPC polymorphisms on the response to platinum-based chemotherapy: a meta-analysis. Onco Targets Ther. 2019;12:3839–3848. https://doi.org/10.2147/OTT.S202617.; Ban N, Takahashi Y, Takayama T, Kura T, Katahira T, Sakamaki S et al. Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide. Cancer Res. 1996;56(15):3577–3582. Available at: https://pubmed.ncbi.nlm.nih.gov/8758929.; Puerta-García E, Urbano-Pérez D, Carrasco-Campos MI, Pérez-Ramírez C, Segura-Pérez A, Calleja-Hernández et al. Effect of DPYD, MTHFR, ABCB1, XRCC1, ERCC1 and GSTP1 on chemotherapy related toxicity in colorectal carcinoma. Surg Oncol. 2020;35:388–398. https://doi.org/10.1016/j.suronc.2020.09.016.; Huang MY, Huang ML, Chen MJ, Lu CY, Chen CF, Tsai PC et al. Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy. Pharmacogenet Genomics. 2011;21(1):18–25. https://doi.org/10.1097/FPC.0b013e3283415124.; Keam B, Im SA, Han SW, Ham HS, Kim MA, Oh DY et al. Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. BMC Cancer. 2008;8:148. https://doi.org/10.1186/1471-2407-8-148.; Badary DM, Elkabsh MM, Mady HH, Gabr A, Kroosh SS. Prognostic and Predictive Role of Excision Repair Cross-complementation Group 1 and Thymidylate Synthase in Colorectal Carcinoma Patients Received FOLFOX Chemotherapy: An Immunohistochemical Study. Appl Immunohistochem Mol Morphol. 2020;28(10):741–747. https://doi.org/10.1097/PAI.0000000000000841.; https://www.med-sovet.pro/jour/article/view/7850
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11Academic Journal
المؤلفون: Aristotelis Bamias, Konstantinos Koutsoukos, Nikos Gavalas, Roubini Zakopoulou, Kimon Tzannis, Nikos Dedes, Anna Boulouta, Charalampos Fragkoulis, Eythymios Kostouros, Athanasios Dellis, Iraklis Mitsogiannis, Ioannis Adamakis, Ioannis Anastasiou, Andreas Skolarikos, Athanasios Papatsoris, Konstantinos Stravodimos, Nikolaos Ferakis, Stamatina Pagoni, Konstantinos Ntoumas, Dionysios Mitropoulos, Charalambos Deliveliotis, Constantinos A. Constantinides, Meletios A. Dimopoulos
المصدر: Current Oncology, Vol 28, Iss 6, Pp 4474-4484 (2021)
مصطلحات موضوعية: ERCC1, bladder cancer, chemotherapy, immunotherapy, vinflunine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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12Academic Journal
المؤلفون: Rahul Sreekumar, Hajir Al‐Saihati, Muhammad Emaduddin, Karwan Moutasim, Massimiliano Mellone, Ashish Patel, Seval Kilic, Metin Cetin, Sule Erdemir, Marta Salgado Navio, Maria Antonette Lopez, Nathan Curtis, Tamer Yagci, John N. Primrose, Brendan D. Price, Geert Berx, Gareth J. Thomas, Eugene Tulchinsky, Alex Mirnezami, A. Emre Sayan
المصدر: Molecular Oncology, Vol 15, Iss 8, Pp 2065-2083 (2021)
مصطلحات موضوعية: DNA repair, EMT, ERCC1, oxaliplatin, ZEB2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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13Academic Journal
المؤلفون: Wendy Muñoz-Montaño, Sae Muñiz-Hernández, Alejandro Avilés-Salas, Rodrigo Catalán, Luis Lara-Mejía, Suraj Samtani-Bassarmal, Andres F. Cardona, Jorge Mendoza-Desión, Daniel Hernández-Cueto, Altagracia Maldonado, Guillermina Baay-Guzmán, Sara Huerta-Yepes, Oscar Arrieta
المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
مصطلحات موضوعية: RRM1, ERCC1, Immunohistochemistry, Biomarkers, Mesothelioma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1471-2407
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14Academic Journal
المؤلفون: Yunxiang Tang, Ruike Zhang, Yinan Li, Shuyu Xu, Hao Wang, Jingzhou Xu, Lei Xiao, Yajing Wang, Jing Du, Yujia Huang, Tong Su
المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
مصطلحات موضوعية: ERCC1, ERCC2, Single nucleotide polymorphism, Quality of life, Depression, Anxiety, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1471-2407
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15Academic Journal
المؤلفون: Yuqiang Zhang, Sufen Cao, Chunyu Zhuang, Jiacheng Chen, Xiaojing Chen, Hong Sun, Shengying Lin, Bailang Lin
المصدر: Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-11 (2021)
مصطلحات موضوعية: Ovarian cancer, ERCC1, Platinum drugs, Meta-analysis, Gynecology and obstetrics, RG1-991
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1757-2215
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16Academic Journal
المؤلفون: Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
المصدر: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-20 (2021)
مصطلحات موضوعية: Purkinje cell degeneration, 5-Ethynylurdine, Nascent RNA, Transcription stress, DNA damage, Ercc1, Neurology. Diseases of the nervous system, RC346-429
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2051-5960
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17Academic Journal
المؤلفون: Sun Min Park, Sung Bong Choi, Yoon Suk Lee, In Kyu Lee
المصدر: Asian Journal of Surgery, Vol 44, Iss 5, Pp 715-722 (2021)
مصطلحات موضوعية: Colorectal neoplasm, KRAS, ERCC1, Oxaliplatin, Resistance, Surgery, RD1-811
وصف الملف: electronic resource
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18Academic Journal
المؤلفون: M. V. Matsko, D. E. Matsko, E. N. Imyanitov, S. S. Sklyar, A. Yu. Ulitin, I. V. Yakovenko, A. G. Ievleva, G. A. Ershov, A. A. Romanko, A. S. Nechaeva
المصدر: Сибирский онкологический журнал, Vol 20, Iss 1, Pp 105-114 (2021)
مصطلحات موضوعية: central nervous system embryonal tumors, neuroblastoma, ganglioneuroblastoma, mutations idh1/2 genes, mgmt gene, ercc1 gene, vegf gene, pdgfra gene, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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19Academic Journal
المصدر: Frontiers in Pharmacology, Vol 13 (2022)
مصطلحات موضوعية: pemetrexed, population pharmacokinetics, ERCC1, CYP3A5, polymorphisms, creatinine clearance, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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20Academic Journal
المؤلفون: Zhifei Liu, Liyong Xing, Yanfeng Zhu, Peng Shi, Gang Deng
المصدر: Heliyon, Vol 8, Iss 6, Pp e09643- (2022)
مصطلحات موضوعية: Bladder cancer, TOP2A, RRM1, ERCC1, Chemotherapy, Science (General), Q1-390, Social sciences (General), H1-99
وصف الملف: electronic resource