المؤلفون: Scott Hackett, Daniela Siegmund, Sergey Nejentsev, Delphine Cuchet-Lourenço, Changxin Wu, Emma Goss, Harald Wajant, Chris M. Bacon, Miguel B. Gaspar, Mofareh AlZahrani, Peter D. Arkwright, Ali Alisaac, Rainer Doffinger, Olivier Papapietro, Lourdes Ceron-Gutierrez, Davide Eletto, Dinakantha S. Kumararatne, Vincent Plagnol, Eman AlIdrissi, Badr AlSaleem, Mario Abinun, Mailis Maes, James Curtis

المساهمون: Cuchet-Lourenço, Delphine [0000-0002-9501-6122], Eletto, Davide [0000-0002-2650-1968], Plagnol, Vincent [0000-0002-5597-9215], Papapietro, Olivier [0000-0001-5072-5235], Bacon, Chris M [0000-0002-8268-2812], Alsaleem, Badr [0000-0003-3348-4550], Maes, Mailis [0000-0002-0266-6557], Alisaac, Ali [0000-0003-1463-4488], Goss, Emma [0000-0002-5277-4249], AlIdrissi, Eman [0000-0003-2462-3571], Wajant, Harald [0000-0002-2005-3949], Kumararatne, Dinakantha [0000-0001-8438-4686], Arkwright, Peter D [0000-0002-7411-5375], Abinun, Mario [0000-0002-7050-3565], Doffinger, Rainer [0000-0002-9841-3617], Nejentsev, Sergey [0000-0002-7528-4461], Apollo - University of Cambridge Repository

المصدر: Cuchet-Lourenço, D, Eletto, D, Wu, C, Plagnot, V, Papapietro, O, Curtis, J, Ceron-Gutierrez, L, Bacon, C M, Hackett, S, Alsaleem, B, Maes, M, Gaspar, M, Alisaac, A, Goos, E, Alidrissi, E, Siegmund, D, Wajant, H, Kumararatne, D, AlZahrani, M S, Arkwright, P, Abinun, M, Doffinger, R & Nejentsev, S 2018, ' Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis and intestinal inflammation ', Science, vol. 361, no. 6404, pp. 810-813 . https://doi.org/10.1126/science.aar2641

مصطلحات موضوعية: 0301 basic medicine, Male, Severe Combined Immunodeficiency/genetics, Necroptosis, medicine.medical_treatment, Arthritis, Inflammation, 03 medical and health sciences, RIPK1, Immune system, Lymphopenia, Lymphopenia/genetics, medicine, Humans, Immunodeficiency, Alleles, Fibroblasts/metabolism, Inflammatory Bowel Diseases/genetics, Multidisciplinary, business.industry, Cytokines/metabolism, Fibroblasts, Receptor-Interacting Protein Serine-Threonine Kinases/genetics, Inflammatory Bowel Diseases, medicine.disease, 3. Good health, Pedigree, 030104 developmental biology, Cytokine, Receptor-Interacting Protein Serine-Threonine Kinases, Immunology, Cytokines, Severe Combined Immunodeficiency, Cytokine secretion, Female, Arthritis/genetics, Mitogen-Activated Protein Kinases, medicine.symptom, business, Mitogen-Activated Protein Kinases/metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4907946e07f00a22725a9c3066251f
https://doi.org/10.1126/science.aar2641

المؤلفون: Delphine, Cuchet-Lourenço, Davide, Eletto, Changxin, Wu, Vincent, Plagnol, Olivier, Papapietro, James, Curtis, Lourdes, Ceron-Gutierrez, Chris M, Bacon, Scott, Hackett, Badr, Alsaleem, Mailis, Maes, Miguel, Gaspar, Ali, Alisaac, Emma, Goss, Eman, AlIdrissi, Daniela, Siegmund, Harald, Wajant, Dinakantha, Kumararatne, Mofareh S, AlZahrani, Peter D, Arkwright, Mario, Abinun, Rainer, Doffinger, Sergey, Nejentsev

المصدر: Science (New York, N.Y.). 361(6404)

مصطلحات موضوعية: Male, Arthritis, Lymphopenia, Receptor-Interacting Protein Serine-Threonine Kinases, Cytokines, Humans, Female, Severe Combined Immunodeficiency, Fibroblasts, Mitogen-Activated Protein Kinases, Inflammatory Bowel Diseases, Alleles, Pedigree

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::201d8004ea923e556107f83c8b559692
https://pubmed.ncbi.nlm.nih.gov/30143752

المؤلفون: Emma Goss-Custard

Resource Type: eBook.

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