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1Academic Journal
المؤلفون: Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W. Grim, Filomena Fezza, Luciano de Petrocellis, Christoph Ullmer, Benno Rothenhäusler, Camille Perret, Noortje van Gils, David Finlay, Christa MacDonald, Andrea Chicca, Marianela Dalghi Gens, Jordyn Stuart, Henk de Vries, Nicolina Mastrangelo, Lizi Xia, Georgios Alachouzos, Marc P. Baggelaar, Andrea Martella, Elliot D. Mock, Hui Deng, Laura H. Heitman, Mark Connor, Vincenzo Di Marzo, Jürg Gertsch, Aron H. Lichtman, Mauro Maccarrone, Pal Pacher, Michelle Glass, Mario van der Stelt
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Elliot D, Mock, Wouter P F, Driever, Mario, van der Stelt
المصدر: Methods in molecular biology (Clifton, N.J.). 2576
مصطلحات موضوعية: HEK293 Cells, Pyridoxal, Phospholipase D, Humans, Fluorescence, Endocannabinoids
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3Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
المؤلفون: Elliot D. Mock, Berend Gagestein, Mario van der Stelt
المصدر: Progress in Lipid Research
مصطلحات موضوعية: Cell Biology, Biochemistry
وصف الملف: application/pdf
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4
المؤلفون: Mario van der Stelt, Constant A. A. van Boeckel, Wouter P F Driever, Elliot D. Mock, Ioli Kotsogianni, Jelle M Vooijs, Carmen S Fonseca, Hans den Dulk
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Pyrimidine, Stereochemistry, Phospholipase D, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Enzyme, chemistry, In vivo, Morpholine, Drug Discovery, Lipophilicity, Molecular Medicine, N-Acylphosphatidylethanolamine, Structure–activity relationship, 030304 developmental biology
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المؤلفون: Elliot D, Mock, Ioli, Kotsogianni, Wouter P F, Driever, Carmen S, Fonseca, Jelle M, Vooijs, Hans, den Dulk, Constant A A, van Boeckel, Mario, van der Stelt
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Structure-Activity Relationship, Pyrimidines, Phospholipases, Phosphatidylethanolamines, Carboxylic Acids, Enzyme Inhibitors, Amides, Article
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6
المؤلفون: Ozge Gunduz-Cinar, Laura I. Castillo, Antonius P A Janssen, Helma van den Hurk, Marjolein Soethoudt, Andrew Holmes, Resat Cinar, Cristina Miliano, Annelot C. M. van Esbroeck, Colleen M Donovan, Pal Pacher, Elliot D. Mock, Aron H. Lichtman, Alexander T Bakker, Jesse Wat, Matthew W. Buczynski, Anouk M F van der Gracht, Tom van der Wel, Ioli Kotsogianni, Vasudev Kantae, Tiemen J Wendel, Xinyu Di, Thomas Hankemeier, Matthias B. Wittwer, Matthew N. Hill, János Pálóczi, Gavin N. Petrie, Uwe Grether, Joshua K. Park, Andrea Martella, Zoltán Varga, Ming Jiang, Daisuke Ogasawara, Giulia Donvito, Benjamin F. Cravatt, Constant A. A. van Boeckel, Bogdan I. Florea, Mario van der Stelt, Mohammed A. Mustafa
المصدر: Nature Chemical Biology, 16(6), 667-675
Nat Chem Biolمصطلحات موضوعية: Male, Cannabinoid receptor, Nape, medicine.medical_treatment, Drug Evaluation, Preclinical, Article, Amidohydrolases, 03 medical and health sciences, chemistry.chemical_compound, Mice, Fatty acid amide hydrolase, Cell Line, Tumor, Lipidomics, medicine, Phospholipase D, Animals, Humans, Enzyme Inhibitors, Receptors, Cannabinoid, Molecular Biology, Cannabinoid Receptor Antagonists, 030304 developmental biology, 0303 health sciences, Behavior, Animal, Molecular Structure, Chemistry, Phosphatidylethanolamines, 030302 biochemistry & molecular biology, Brain, Cell Biology, Anandamide, Blood Proteins, Fear, Lipid Metabolism, Endocannabinoid system, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, lipids (amino acids, peptides, and proteins), Cannabinoid, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Tom van der Wel, Tiemen J Wendel, Gerard J. P. van Westen, Yvonne Tran, Ming Jiang, Florian Mohr, Karol Al Ayed, Anna F. Stevens, Andrea Martella, Vasudev Kantae, Mario van der Stelt, Tim P Ofman, Lindsey Burggraaff, Juan Zhou, Thomas Hankemeier, Elliot D. Mock, Xinyu Di, Nicky de Koster
المصدر: Journal of Medicinal Chemistry, 63(17), 9340-9359
International Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
International Journal of Medicinal Chemistry, 63(17), 9340-9359. AMER CHEMICAL SOCمصطلحات موضوعية: Models, Molecular, Protein Conformation, Inflammation, 01 natural sciences, Article, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Protein structure, Drug Discovery, medicine, Humans, Structure–activity relationship, Enzyme Inhibitors, 030304 developmental biology, 0303 health sciences, Phospholipase A, Hep G2 Cells, Anandamide, Amides, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Biochemistry, Phospholipases, Acyltransferase, Molecular Medicine, Arachidonic acid, medicine.symptom, Acyltransferases, Cysteine
وصف الملف: application/pdf
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المؤلفون: Hans den Dulk, Laura Mulder, Lindsey Burggraaff, Thomas Hankemeier, Juan Zhou, Marc P. Baggelaar, Andrea Martella, Bogdan I. Florea, Alexander T Bakker, Mario van der Stelt, Karol Al-Ayed, Chun T. Li, Gerard J. P. van Westen, Herman S. Overkleeft, Vasudev Kantae, Elliot D. Mock, Xinyu Di, Sebastian H. Grimm
المصدر: ACS Chemical Biology, 14(2), 164-169
ACS Chemical Biologyمصطلحات موضوعية: 0301 basic medicine, Proteomics, 01 natural sciences, Biochemistry, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Phospholipase A2, law, Lipolysis, Animals, Humans, Letters, Lipase, Enzyme Inhibitors, Host factor, biology, 010405 organic chemistry, Chemistry, Activity-based proteomics, Proteins, General Medicine, Amides, 0104 chemical sciences, Phospholipases A2, 030104 developmental biology, biology.protein, Recombinant DNA, Molecular Medicine, Arachidonic acid
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المؤلفون: Sascha Hoogendoorn, Hans van den Elst, Gijsbert A. van der Marel, Richard J. B. H. N. van den Berg, Anneke Strijland, Johannes M. F. G. Aerts, Elliot D. Mock, Wilma E. Donker-Koopman, Herman S. Overkleeft
المصدر: European Journal of Organic Chemistry. 2015:4437-4446
مصطلحات موضوعية: chemistry.chemical_classification, Inhibitory potency, Enzyme, chemistry, Stereochemistry, Organic Chemistry, Carborane, Glucosylceramide synthase, Physical and Theoretical Chemistry, Glucosylceramidase
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المؤلفون: Marjolein Soethoudt, Filomena Fezza, Tom van der Wel, Mauro Maccarrone, Annelot C. M. van Esbroeck, Marc P. Baggelaar, Chris I. De Zeeuw, Giel Hendriks, Guy Shpak, Bogdan I. Florea, Luciano De Petrocellis, Mario van der Stelt, Ilse L. Baak, Hui Deng, Daisuke Ogasawara, Marco Allarà, Vincenzo Di Marzo, Hans den Dulk, Elliot D. Mock, Zhanmin Lin, Armand B. Cognetta, Steven A. Kushner, Thomas Hankemeier, Benjamin F. Cravatt, Femke M.S. de Vrij, Mark van der Kroeg, Vasudev Kantae, Antonius P A Janssen, Herman S. Overkleeft
المساهمون: Psychiatry, Neurosciences, Netherlands Institute for Neuroscience (NIN)
المصدر: Science (N. Y., N.Y.) 356 (2017): 1084–1087. doi:10.1126/science.aaf7497
info:cnr-pdr/source/autori:van Esbroeck, Annelot C. M.; Janssen, Antonius P. A.; Cognetta, Armand B., III; Ogasawara, Daisuke; Shpak, Guy; van der Kroeg, Mark; Kantae, Vasudev; Baggelaar, Marc P.; de Vrij, Femke M. S.; Deng, Hui; Allara, Marco; Fezza, Filomena; Lin, Zhanmin; van der Wel, Tom; Soethoudt, Marjolein; Mock, Elliot D.; den Dulk, Hans; Baak, Ilse L.; Florea, Bogdan I.; Hendriks, Giel; de Petrocellis, Luciano; Overkleeft, Herman S.; Hankemeier, Thomas; De Zeeuw, Chris I.; Di Marzo, Vincenzo; Maccarrone, Mauro; Cravatt, Benjamin F.; Kushner, Steven A.; van der Stelt, Mario/titolo:Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474/doi:10.1126%2Fscience.aaf7497/rivista:Science (N. Y., N.Y.)/anno:2017/pagina_da:1084/pagina_a:1087/intervallo_pagine:1084–1087/volume:356
Science, 356(6342), 1084-1087. American Association for the Advancement of Science
Science, 356(6342), 1084-1087. American Association for the Advancement of Science (AAAS)
SCIENCE, 356(6342), 1084-1087
SCIENCEمصطلحات موضوعية: 0301 basic medicine, Nervous system, Drug, BIA 10-2474, Pyridines, media_common.quotation_subject, Biology, Pharmacology, Phase I as Topic, Cross Reactions, Amidohydrolases, Cell Line, Cyclic N-Oxides, 03 medical and health sciences, Fatty acid amide hydrolase, Cell Line, Tumor, medicine, Journal Article, Humans, Urea, Clinical Trials, FAAH, Protein Interaction Maps, Settore BIO/10, media_common, Neurons, Analgesics, Multidisciplinary, Tumor, Clinical Trials, Phase I as Topic, TRP channels, Activity-based proteomics, Neurotoxicity, Anti-Anxiety Agents, Pyridazines, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, nervous system, Cell culture, Lipase inhibitors
وصف الملف: application/pdf
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المؤلفون: Jaroslaw Mazurek, Gijsbert A. van der Marel, Adrianus M. C. H. van den Nieuwendijk, Gerjan de Bruin, Sascha Hoogendoorn, Herman S. Overkleeft, Elliot D. Mock, Bogdan I. Florea
المصدر: Chemical communications (Cambridge, England). 52(21)
مصطلحات موضوعية: Boron Compounds, Proteasome Endopeptidase Complex, Stereochemistry, Adamantane, Phenylalanine, Cell, Strecker amino acid synthesis, Sulfonium Compounds, Stereoisomerism, 010402 general chemistry, 01 natural sciences, Catalysis, Bortezomib, chemistry.chemical_compound, immune system diseases, hemic and lymphatic diseases, Cell Line, Tumor, Materials Chemistry, medicine, Humans, 010405 organic chemistry, Chemistry, Metals and Alloys, Enantioselective synthesis, General Chemistry, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, medicine.anatomical_structure, Proteasome, Ceramics and Composites, Proteasome inhibitor, Proteasome Inhibitors, medicine.drug
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المؤلفون: Jonathan A. Ellman, Hao Li, Wouter A. van der Linden, Kristina Oresic Bender, Leslie O. Ofori, Ehud Segal, Mateo Sanchez Lopez, Matthew Bogyo, Martijn Verdoes, Carl G. Figdor, Elliot D. Mock, Gopal K. Datta, Somenath Chowdhury
المصدر: Journal of the American Chemical Society, 137, 4771-7
Journal of the American Chemical Society, 137, 14, pp. 4771-7مصطلحات موضوعية: Proteases, Infrared Rays, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Color, Biochemistry, Catalysis, Article, Substrate Specificity, Mice, Colloid and Surface Chemistry, Immune system, In vivo, Animals, Humans, Cathepsin S, Fluorescent Dyes, Cathepsin, Chemistry, Optical Imaging, Mammary Neoplasms, Experimental, General Chemistry, Dendritic Cells, Cathepsins, In vitro, RAW 264.7 Cells, Drug Design, Function (biology), Cysteine
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13
المؤلفون: Alexei F. Kisselev, Paul P. Geurink, Annet E. M. Blom, Anne C. Mirabella, Christoph Driessen, Gijs A. van der Marel, Bogdan I. Florea, Herman S. Overkleeft, Mario van der Stelt, Wouter A. van der Linden, Elliot D. Mock, Gerjan de Bruin, Michael Groll, Nerea Gallastegui, Mathias J. Voges
المصدر: Journal of medicinal chemistry
مصطلحات موضوعية: Models, Molecular, Cell Membrane Permeability, Pharmacology, 01 natural sciences, Article, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Doxorubicin, Trypsin, Amino Acids, Multiple myeloma, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Bortezomib, medicine.disease, Carfilzomib, 0104 chemical sciences, 3. Good health, Amino acid, Proteasome, chemistry, Biochemistry, Cell culture, Drug Design, Molecular Medicine, Proteasome Inhibitors, medicine.drug
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