المؤلفون: Ellen K Gagliani, Lisa M Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A Kovall

المصدر: PLoS Genetics, Vol 18, Iss 8, p e1010335 (2022)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/3d3ef8ff2e0245a7bfb1cb014a49f333

المؤلفون: Yi Kuang, Anna Pyo, Natanel Eafergan, Brittany Cain, Lisa M Gutzwiller, Ofri Axelrod, Ellen K Gagliani, Matthew T Weirauch, Raphael Kopan, Rhett A Kovall, David Sprinzak, Brian Gebelein

المصدر: PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/46e826c091ea4d9db920f08826b85963

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/journal_contribution/List_of_oligonucleotide_sequences_used_to_generate_the_labeled_probes_used_in_the_electrophoretic_mobility_shift_assays_/16679343

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s012

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/journal_contribution/List_of_DNA_sequences_used_to_generate_all_the_synthetic_reporter_and_expression_transgenic_constructs_/16679346

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s013

المؤلفون: Ellen K. Gagliani, Lisa M. Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J. Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A. Kovall

المصدر: PLoS genetics. 18(8)

مصطلحات موضوعية: Mammals, Cancer Research, Scalp, Receptors, Notch, Skull, Limb Deformities, Congenital, DNA, Scalp Dermatoses, Ectodermal Dysplasia, Genetics, Animals, Drosophila Proteins, Humans, Drosophila, Molecular Biology, Co-Repressor Proteins, Genetics (clinical), Ecology, Evolution, Behavior and Systematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dce116c72ecde6d05251bcac93ec40
https://pubmed.ncbi.nlm.nih.gov/35951645

المؤلفون: Ellen K. Gagliani, Brian Gebelein, Tilman Borggrefe, Yi Kuang, Patrick J. Dolph, Rhett A. Kovall, Phillipp Hoffmeister, Aleksandra Turkiewicz, Emily Harding-Theobald, Yoshinobu Odaka, Franz Oswald, Stefanie Hauff, Lisa M. Gutzwiller

مصطلحات موضوعية: Cofactor binding, RBPJ, Chemistry, Notch signaling pathway, Wild type, Allele, Transcription factor, Null allele, Cell biology, Hairless

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48a3d161f94cc06c845756d7f7deccc1
https://doi.org/10.1101/2021.09.24.461537

المؤلفون: Brian Gebelein, Ellen K. Gagliani, Raphael Kopan, Natanel Eafergan, Rhett A. Kovall, Yi Kuang, Matthew T. Weirauch, Anna Pyo, Brittany Cain, Lisa M. Gutzwiller, Ofri Axelrod, David Sprinzak

المصدر: PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)
PLoS Genetics

مصطلحات موضوعية: Cancer Research, Life Cycles, Gene Expression, Electrophoretic Mobility Shift Assay, Restriction Fragment Mapping, QH426-470, Biochemistry, Larvae, Genes, Reporter, Transcription (biology), Gene expression, Drosophila Proteins, Genetics (clinical), Receptors, Notch, Chemistry, Drosophila Melanogaster, Eukaryota, Animal Models, Cell biology, Insects, Enhancer Elements, Genetic, Experimental Organism Systems, Lac Operon, Drosophila, Chemical characterization, Research Article, Transcriptional Activation, Arthropoda, DNA transcription, Notch signaling pathway, DNA binding assay, Biology, Research and Analysis Methods, DNA-binding protein, Model Organisms, DNA-binding proteins, Binding analysis, Genetics, Animals, Electrophoretic mobility shift assay, Gene Regulation, Molecular Biology Techniques, Enhancer, Molecular Biology, Psychological repression, Transcription factor, Ecology, Evolution, Behavior and Systematics, Binding Sites, Gene Mapping, Organisms, Biology and Life Sciences, Proteins, Invertebrates, Regulatory Proteins, Hairless, Repressor Proteins, Gene Expression Regulation, Animal Studies, Notch binding, Zoology, Entomology, Transcription Factors, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de114790586f27d05d91e1e85e0921ad
https://doaj.org/article/46e826c091ea4d9db920f08826b85963

المؤلفون: Benedetto Daniele, Giaimo, Ellen K, Gagliani, Rhett A, Kovall, Tilman, Borggrefe

المصدر: Advances in experimental medicine and biology. 1287

مصطلحات موضوعية: Gene Expression Regulation, Receptors, Notch, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Humans, Chromatin, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e05702a6775b8f7ab35c5ce651b8dd99
https://pubmed.ncbi.nlm.nih.gov/33034023

المؤلفون: Tilman Borggrefe, Ellen K. Gagliani, Rhett A. Kovall, Benedetto Daniele Giaimo

المصدر: Advances in Experimental Medicine and Biology ISBN: 9783030550301

مصطلحات موضوعية: 03 medical and health sciences, 0302 clinical medicine, RBPJ, Notch signaling pathway, Context (language use), 030212 general & internal medicine, Signal transduction, HES1, Biology, Corepressor, Transcription factor, Cell biology, Chromatin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a77fd14225265a2b9ed29334d4bcf37
https://doi.org/10.1007/978-3-030-55031-8_2

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/EMSA_quantification_and_modeling_of_DNA_binding_states_/16679295

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s001

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Specificity_of_1xSPS_sub_15_sub_2xCSL_sub_17_sub_and_2xCSL_sub_17_sub_mut_probes_as_unlabeled_competitors_for_Su_H_/16679301

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s002

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/cisBP_analysis_of_2xCSL_sub_17_sub_1xSPS_sub_15_sub_2xCSL15_and_1xSPS17_sequences_for_additional_transcription_factor_binding_site_motifs_/16679304

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s003

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/CSL_and_SPS_probes_with_different_flanking_sequences_show_similar_behaviors_in_EMSAs_/16679310

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s004

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/2xCSL_sub_17_sub_and_1xSPS_sub_15_sub_reporters_fail_to_mediate_Notch_activation_in_mesectoderm_cells_/16679325

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s008

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/_i_12xCSL_sub_17_sub_-lacZ_i_and_i_6xSPS_sub_15_sub_-lacZ_i_transgenic_reporters_behave_similarly_in_two_different_loci_/16679316

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s006

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Synthetic_CSL_and_SPS_reporters_with_distinct_flanking_sequences_significantly_differ_in_expression_activity_in_larval_imaginal_discs_/16679322

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s007

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/lexA-H_sup_232_263_sup_fusion_protein_but_not_lexA_or_H_sup_232_263_sup_alone_represses_the_i_lacZ_i_reporters_driven_by_lexA_operator_and_CSL_SPS_binding_sites_/16679334

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s010

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Analysis_of_synthetic_SPS_and_CSL_reporter_activity_under_conditions_of_either_GFP_or_Hairless_overexpression_/16679328

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s009

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/dataset/Spreadsheet_containing_all_the_raw_data_used_to_generate_the_graphs_within_the_manuscript_/16679337

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s011

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/The_Notch-CSL-Mastermind_NCM_complex_binds_the_SPS_sequence_cooperatively_i_in_vitro_i_/16679349

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.g001